Clinical trials: Preterm Labour
Preterm Birth, Obstetric Labor, Premature
Prevention of Preterm Labor in Patients With a Previous Episode of Threatened Preterm Labor With Progesterone
The purpose of this study is to determine if the use of 250 mg of intramuscular progesterone biweekly can reduce the incidence of preterm labor in patients with an episode of threatened preterm labor during the current pregnancy.
- Trial name
- NCT01317225
- Testing
- 17 α hydroxyprogesterone caproate
- Where
- Panama
- Volunteers
- 80 people
- Sponsor
- Saint Thomas Hospital, Panama
Pregnancy, Vulvovaginitis
Maternal and Perinatal Outcome in Women With History of Premature Labor in Previous Pregnancy
Introduction: Preterm labor (PTL) is an important obstetric intercurrence that affects 5 to 10% of pregnancies. Among the known factors of PTL etiology are PTL occurrence in previous pregnancies, multiple pregnancies…
- Conditions
- Pregnancy, Vulvovaginitis, Uterine Cervicitis, Pregnancy Outcome
- Trial name
- NCT01375439
- Testing
- Active search of lower genital tract infections
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Pregnancy Complications, Preterm Birth
Group Antenatal/Postnatal Care in Rwanda
The focus of this work is to improve antenatal care (ANC) and postnatal care (PNC) at the health center level in five districts in Rwanda (Bugesera, Burera, Nyamasheke, Nyarugenge, and Rubavu).
- Conditions
- Pregnancy Complications, Preterm Birth, Preterm Labor, Stillbirth
- Trial name
- PTBi Rwanda (NCT03154177)
- Testing
- Group ANC/PNC, Ultrasound+Pregnancy Testing
- Where
- 2 sites in Rwanda
- Volunteers
- 26,381 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Apnea of Newborn, Preterm Labor
Analyze Changes in Respiratory Rate When Using the Scare Respirator
Pilot study of 10 preterm, who are going to be randomly placed to 3 phases : 2 hour of basal observation of respiratory rate, heart rate, saturation, NIPS and aEEG recording, 2 hours with a 20cycles/minute with "scare…
- Trial name
- RESPSUS (NCT04584814)
- Testing
- without any device, scare ventilator at 20, scare ventilator at 40
- Where
- Chile
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Cesarean Delivery Affecting Fetus, Preterm Labor
Baby Smell Visual Stimulus Program Cortical and Breast Oxygenation Milk Amount Mother-Infant Attachment
In this study, the effect of infant odor and visual stimulus program applied to mothers who had delivered by cesarean section and whose babies were taken to the NICU on cortical and breast oxygenation (rSO2), amount of breast…
- Trial name
- NCT06058208
- Testing
- Olfactory stimulation, Visual stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Preterm Labor, Preterm Labor With Preterm Delivery in Third Trimester
The Effect of Facilitated Tucking After Vaginal Delivery on Late Preterm Stress, Comfort and Physiological Parameters
Objective: It is aimed to examine the effect of facilitated tucking after vaginal delivery on late preterm stress, comfort and physiological parameters. Design: The study was designed randomized controlled study.
- Conditions
- Preterm Labor, Preterm Labor With Preterm Delivery in Third Trimester, Preterm Spontaneous Labor With Preterm Delivery
- Trial name
- NCT05430321
- Testing
- Assessment of physiological parameters, Assessment of Stress, Assessment of Comfort
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Fetal Heart Rate or Rhythm Abnormality Affecting Fetus
Effect of Dexamethasone on Fetal Heart Rate Variables In Case Of Imminent Preterm Labor
Effect of dexamethasone on fetal heart rate variability in case of preterm labour: prospective cohort study
- Trial name
- NCT05374135
- Where
- Egypt
- Volunteers
- 97 people
- Sponsor
- Assiut University
Placenta Previa
Nifedipine Versus Magnesium Sulfate for Prevention of Preterm Labor in Symptomatic Placenta Previa
Antepartum hemorrhage is defined as bleeding from or within the female genital tract, occurring from 28+0 weeks of pregnancy and till delivery of the fetus.
- Trial name
- NCT03542552
- Testing
- Magnesium Sulfate, Nifedipine
- Where
- Egypt
- Volunteers
- 176 people
- Sponsor
- Assiut University
Obstetric Labour, Premature
Follow up Study to Assess Long Term Safety and Outcomes in Infants and Children Born to Mothers Participating in Retosiban Treatment Studies
The primary objective of this study is to assess the safety and outcomes of infants and children who were exposed to retosiban or comparator in utero in the Phase III spontaneous preterm labor (SPTL) treatment studies, to provide…
- Trial name
- ARIOS (NCT02292784)
- Testing
- Retosiban, Atosiban
- Where
- 26 sites in United States, Belgium and 9 more
- Volunteers
- 98 people
- Sponsor
- GlaxoSmithKline
RSV Infections, RSV Immunisation
A Clinical Trial on Safety in Pregnant Women and How Well the Infant is Protected Against RSV-associated Lower Respiratory Tract Infection When the Pregnant Woman Receives the Approved RSV Vaccine Compared to a Placebo.
Respiratory syncytial virus (RSV) is a virus that often affects children during childhood. Even though most cases of RSV are mild, it can cause serious disease and even death - especially in very young babies, babies born too…
- Conditions
- RSV Infections, RSV Immunisation, Preterm Labour
- Trial name
- NCT06955728
- Testing
- Vaccine
- Where
- 11 sites in Ghana, Kenya and 2 more
- Volunteers
- 13,000 people, healthy volunteers welcome
- Sponsor
- University of Witwatersrand, South Africa
Preterm Labor
Uterine Electrical Activity Before and After Progesterone Treatment for Preterm Labor
This study will examine the effects of various formulations of progesterone on uterine electromyographic (EMG) activity in pregnant patients in premature labor to determine if progesterone will suppress uterine electrical…
- Trial name
- NCT01406197
- Testing
- Experimental: Vaginal progesterone, Experimental: Topical progesterone, Experimental: Intramuscular progesterone
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Term Delivery With Preterm Labor, Third Trimester, Term Delivery With Preterm Labor, Unspecified Trimester
Tidal Neonatal NO, Vitamins A and D, and Infant Lung Disease - The AD-ON Study
Children born prematurely are of greater risk of developing chronic lung disease (Bronchopulmonary Dysplasia). With an increase in the amount of premature children, we expect an increasing number of children with BPD.
- Conditions
- Term Delivery With Preterm Labor, Third Trimester, Term Delivery With Preterm Labor, Unspecified Trimester, Bronchopulmonary Dysplasia
- Trial name
- NCT01722760
- Testing
- measurements
- Where
- 2 sites in Denmark
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Hillerod Hospital, Denmark
Obstetric Labor, Premature
Vaginal Indomethacin for Preterm Labor
Indometacin is a cyclooxygenase agent from the NSAID family that has been used to treat preterm contractions since the 70's by preventing the synthesis of prostaglandins.
- Trial name
- TOCOMED (NCT04404686)
- Testing
- Indomethacin, Nifedipine
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Anxiety During Pregnancy, Mental Fatigue
The Effect of Mandala Coloring on Anxiety and Mental Fatigue in Pregnant Women Diagnosed With Threatened Preterm Labor
The research will be conducted in a pre-test-post-test control group randomized control design. The aim is to examine the effect of mandala work on anxiety and mental fatigue in pregnant women diagnosed with threatened preterm…
- Conditions
- Anxiety During Pregnancy, Mental Fatigue, Mandala
- Trial name
- NCT06589648
- Testing
- mandala painting
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Preterm Labor, Tobacco Use Disorder
Omega-3 Fatty Acids for Smoking Cessation in Pregnancy
Smoking is the most important modifiable risk factor for adverse pregnancy outcomes including preterm birth, neonatal death, and maternal complications.
- Trial name
- INFANTS (NCT04417595)
- Testing
- Fish Oil (Containing Omega-3 Acids), Olive Oil
- Where
- United States
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Premature Birth, Preterm Labor
Lockdown Impact on Spontaneous Premature Birth in a Level III NICU
Preterm labor (PL) is the leading cause of hospitalization during pregnancy and premature birth the leading cause of fetal morbidity and mortality in France.
- Trial name
- CONFINéo (NCT04605172)
- Testing
- hospitalization for premature birth
- Where
- France
- Volunteers
- 812 people
- Sponsor
- Central Hospital, Nancy, France
Preterm Labor
Use of Pessary in Case of Cervical Insufficiency and Short Cervix
Prematurity is the most important cause of obstetric morbidity and mortality. Health centers and obstetricians are trying to reduce the preterm birth rate by taking into account the permanent effects of premature birth on human…
- Trial name
- NCT03096691
- Testing
- cervical pessary
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Bedrest, Premature Labor
Bed Rest for Threatened Preterm Labor. Pilot Study
The aim of the pilot trial is to assess at what extend women with arrested threatened preterm labor change their activity patterns at home in response to bed rest prescription.
- Trial name
- NCT00873314
- Testing
- Bed rest, Activity restriction
- Where
- Uruguay
- Volunteers
- 46 people
- Sponsor
- Institute for Clinical Effectiveness and Health Policy
Polycystic Ovary Syndrome, Preterm Birth
Metabolic and Endocrine Status in Women With Prior Preterm Birth
The prevalence of preterm birth is rising in most western countries. The causes of preterm birth is not fully understood and seem to be multifactorial.
- Conditions
- Polycystic Ovary Syndrome, Preterm Birth, Diabetes Mellitus
- Trial name
- NCT01355536
- Where
- Norway
- Volunteers
- 262 people
- Sponsor
- Namsos Hospital
Cervical Length, Preterm Birth
Development of a Screening Tool By Utilising Cervical Length Measurement In Relation To Body Mass Index (BMI) For Early Identification And Intervention Of Preterm Birth
This is a prospective study where pregnant women between 16-24 weeks gestation attending the Antenatal Clinic, Fetomaternal clinic or Obstetrics \& Gynaecology Admission Centre (OGAC) at Hospital Serdang or Hospital Pengajar UPM…
- Trial name
- NCT04922671
- Where
- 2 sites in Malaysia
- Volunteers
- 145 people
- Sponsor
- Universiti Putra Malaysia