Clinical trials: Preterm Neonates
Infant, Very Low Birth Weight
Urine VEGF Levels in Very Low Birth Weight (VLBW) Infants
VLBW infants are at risk of developing retinopathy of prematurity (ROP). In the first phase of ROP there is a down-regulation of retinal VEGF-expression because of postnatal relative hyperoxia, followed by an upregulation of VEGF…
- Trial name
- NCT00799721
- Where
- Germany
- Volunteers
- 160 people
- Sponsor
- Charite University, Berlin, Germany
Neonatal Disease, Nursing Caries
Effect of an Incubator Cover on Term and Preterm Neonates' Vital Signs
The aim of this study is to evaluate the effect of an incubator cover on the vital signs of term and preterm neonates hospitalized in a neonatal intensive care unit.
- Trial name
- NCT05892809
- Testing
- use an incubator cover
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people
- Sponsor
- Maltepe University
Preterm Infants, Infant, Low Birth Weight
Effects of Early Yakson Touch and Kinesthetic Stimulation on the Development of High Risk Neonates
The role of physiotherapy interventions in treatment of high risk infants has not been established even after a number of studies.
- Trial name
- YTKS (NCT02815904)
- Testing
- Yakson touch, Conventional handling, Kinesthetic stimulation
- Where
- India
- Volunteers
- 28 people
- Sponsor
- Asir John Samuel
Milk Expression, Breast, Nutrition
Effect of Cırcadıan Feedıng on Growth Parameters of Preterm Newborn
This study was planned as a randomized controlled experimental study to determine the effect of circadian feeding on the growth parameters of preterm newborns.
- Trial name
- NCT06857149
- Testing
- Human milk, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ayse Sonay Turkmen, Prof.Dr
Preterm Birth, Prematurity
Parent-child Interactions, Child Developmental Health, and Health System Costs at 6 Months Corrected Age
The aim of this novel health services research proposal is to assess the longer-term outcomes, to 6 months corrected age, of an adapted Family Integrated Care (FICare) model of care for moderate and late preterm infants admitted…
- Conditions
- Preterm Birth, Prematurity, Infant,Premature, Infant Development
- Trial name
- NCT03357458
- Testing
- Family Integrated Care
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- University of Calgary
Premature Infant, Developmental Delay
A Parent Administered Sensorimotor Intervention and Developmental Outcome of Preterm Infants
Advances in medical technologies over the last three decades have increased survival rates in infants born preterm . Preterm infants are at high risk of developing developmental delays.
- Trial name
- NCT03836326
- Testing
- Sensorimotor intervention, Control, Story telling attention refocusing intervention
- Where
- Canada
- Volunteers
- 94 people
- Sponsor
- Dr. Sandra Fucile
Neonatal Resuscitation, Infant, Premature
Heart Rate Evaluation and Resuscitation Trial in Preterm Neonates
The purpose of this study is to determine whether using electrocardiograms (ECGs) during resuscitation of preterm infants (less than 31 weeks gestation) will decrease the amount of time it takes from birth for heart rate (HR) to…
- Trial name
- HEART (NCT03133663)
- Testing
- Electrocardiogram group, Pulse oximeter and auscultation group
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Texas Southwestern Medical Center
Premature, Retinopathy of Prematurity
Comfort Level in Premature Infants Undergoing Retinopathy of Prematurity Screening
Retinopathy of prematurity (ROP) screening is a routine yet painful procedure for premature infants, often necessitating pharmacological mydriasis.
- Conditions
- Premature, Retinopathy of Prematurity, Pain
- Trial name
- NCT07016984
- Testing
- standard phototherapy eye patches
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Istanbul Nisantasi University
Hypertension, Diabetes
Renin and Aldosterone Levels in the Preterm Neonate At Risk for Hypertension
The purpose of this study is to find out if mothers with high blood pressure (Hypertension) and/or diabetes have babies with high levels of different substances (that help to regulate blood pressure, called Renin and Aldosterone)…
- Conditions
- Hypertension, Diabetes, Infants Small for Gestational Age
- Trial name
- NCT01549444
- Testing
- presence of maternal risk factor for hypertension
- Where
- 2 sites in Canada
- Volunteers
- 76 people
- Sponsor
- Ottawa Hospital Research Institute
Bronchopulmonary Dysplasia
Early Prediction of Bronchopulmonary Dysplasia in Preterm Infants Using Clinical Data
Early Prediction of Bronchopulmonary Dysplasia in Preterm Infants Using Clinical Data from the First Three Postnatal Weeks with Large Language Models: A Retrospective Study This retrospective, observational study aims to evaluate…
- Trial name
- NCT07525167
- Testing
- Artificial Intelligence-Based Risk Prediction
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Konya City Hospital
Preterm Birth Complication
Serial Brain MRI in Hospitalized Preterm Infants
The purpose of this research study is to use serial magnetic resonance imaging (MRI) to define the timing and factors associated with brain injury as well as the pattern of brain growth of very preterm infants during…
- Trial name
- NCT06052865
- Testing
- SENSE-plus: The Supporting and Enhancing NICU Sensory Experiences 2nd Edition (SENSE II) program, SENSE: The Supporting and Enhancing NICU Sensory Experiences 2nd Edition (SENSE II) program, Reference/ Standard of care
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Brigham and Women's Hospital
Infant, Premature, Infant, Newborn
A Study of Cisapride in Premature Infants With Feeding Problems
The purpose of this study is to evaluate the effectiveness of Cisapride in improving feeding problems in premature newborn infants.
- Trial name
- NCT01281566
- Testing
- Cisapride
- Volunteers
- 8 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Infant, Newborn, Diseases, Cardiovascular Insufficiency
Hydrocortisone for Term Hypotension
This trial will evaluate the effects of a 7-day course of hydrocortisone therapy on short-term morbidity, cardiovascular function, long-term neurodevelopment, and mortality in critically ill, term and late preterm infants…
- Trial name
- NCT01954056
- Testing
- Hydrocortisone
- Where
- 18 sites in United States
- Volunteers
- 12 people
- Sponsor
- NICHD Neonatal Research Network
Premature Birth
HeartLight Pulse Study: Evaluation of Heart Rate Using an Electronic Stethoscope and Pre Placed ECG in the Delivery Room
This study will evaluate the accuracy of both an electronic stethoscope and electrocardiogram (ECG) to evaluate heart rate in neonatal patients in the delivery suite.
- Trial name
- HLPulseS (NCT02747069)
- Testing
- NICU electronic stethoscope, Newborns <32 weeks and ECG
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Nottingham
Bronchopulmonary Dysplasia
Analysis of BPD in Premature Infants With Typical Imaging Changes
Bronchopulmonary dysplasia (BPD) is a common chronic respiratory disease in preterm infants. The increase in the survival rate of premature babies following the improvement of perinatal treatment and care has caused an increase…
- Trial name
- NCT04163822
- Testing
- no intervention
- Where
- China
- Volunteers
- 256 people
- Sponsor
- Wang Jianhui
Prematurity, Neonatal Encephalopathy
Evaluating the NeoTree in Malawi and Zimbabwe
Neonatal mortality remains unacceptably high. Globally, the majority of mothers now deliver in health facilities in low resource settings where quality of newborn care is poor.
- Conditions
- Prematurity, Neonatal Encephalopathy, Neonatal Sepsis, Neonatal Death
- Trial name
- NCT05127070
- Testing
- Neotree
- Where
- 5 sites in Malawi, Zimbabwe
- Volunteers
- 19,000 people
- Sponsor
- University College, London
Preterm Birth, Oxygen Toxicity
Fetal Haemoglobin and Cerebral and Peripheral Oxygenation.
The aim of this study is to investigate the relationship between cerebral and peripheral oxygenation and oxygen extraction, as measured by NIRS (near-infrared spectroscopy ), and the FHbF (fraction of fetal hemoglobin) and…
- Conditions
- Preterm Birth, Oxygen Toxicity, Fetal Hemoglobin
- Trial name
- HbFIN (NCT04802629)
- Testing
- Near-infrared spectroscopy
- Where
- Austria
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Infant, Newborn, Diseases, Prematurity
Prophylactic Surfactant by Thin Endotracheal Catheter for Preterm Infants At Birth: the ProTeCt Trial
The goal of this clinical trial is to learn whether giving surfactant through a thin endotracheal catheter to extremely premature babies shortly after birth reduces the number of them who are ventilated in the first 3 days of…
- Conditions
- Infant, Newborn, Diseases, Prematurity, Prematurity; Extreme, Respiratory Distress Syndrome in Premature Infant
- Trial name
- proTeCt (NCT06557551)
- Testing
- Thin catheter surfactant
- Where
- Ireland
- Volunteers
- 164 people
- Sponsor
- University College Dublin
Perinatal Care
Effects of Hydrotherapy in Pain and Quality of Sleep's Cycles in Preterm Newborn on Neonatal Intensive Care Units
Researchers suggest that the protection of the cycles of sleep is essential for neurodevelopment, learning, memory and preservation of brain plasticity to the individual's life.
- Trial name
- hydrotherapy (NCT00785837)
- Testing
- Aquatic Physical Therapy
- Where
- Brazil
- Volunteers
- 8 people
- Sponsor
- Universidade Luterana do Brasil
Respiratory Distress Syndrome
Impact of Different Modes of Noninvasive Ventilation on Regional Oximetry and Hemodynamics in Premature Newborn
The purpose of this study is to examine the blood flow and the delivery of oxygen to the brain and gut in preterm babies while they are supported with two modes of breathing machine and compare these two methods to see if one…
- Trial name
- NCT01942967
- Testing
- Echocardiography, Near Infrared Spectroscopy Monitoring
- Where
- 2 sites in Canada
- Volunteers
- 10 people
- Sponsor
- University of Manitoba
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