Clinical trials: Prevention & Control
Bloody Diarrhea, STEC, Unspecified
Phase 2/3 Study to Evaluate PK, Safety & Efficacy of INM004 in STEC Positive Pediatric Patients for Prevention of HUS
The investigational medicinal product (IMP), INM004, proposes to neutralize the toxin in the bloodstream to prevent the interaction of the Stx with the specific receptor, by means of a polyclonal antibody to be administered upon…
- Conditions
- Bloody Diarrhea, STEC, Unspecified, Hemolytic-Uremic Syndrome, Pediatric Kidney Disease
- Trial name
- NCT04132375
- Testing
- INM004
- Where
- 7 sites in Argentina
- Volunteers
- 11 people
- Sponsor
- Inmunova S.A.
Tuberculosis
Randomized Controlled Trial of Percutaneous and Intradermal BCG Vaccination.
An open label, randomized, controlled, equivalency trial to compare the efficacy of the percutaneous route of administration with the intradermal route of administration of Japanese (Tokyo) 172 BCG, in the prevention of…
- Trial name
- NCT00242047
- Testing
- Japanese (Tokyo) 172 Bacille Calmette Guerin (BCG).
- Where
- South Africa
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Diarrhea, Antibiotic Associated Diarrhea
Lactobacillus Reuteri DSM 17938 in the Prevention of Antibiotic-associated Diarrhea in Children: Protocol of a Randomized Controlled Trial
The aim of this study is to assess the effect of Lactobacillus reuteri DSM 17938 administration for the prevention of diarrhea and AAD in children.
- Trial name
- NCT02871908
- Testing
- Lactobacillus reuteri DSM 17938
- Where
- Poland
- Volunteers
- 250 people
- Sponsor
- Medical University of Warsaw
Depressive Symptoms, Remited Major Depressive Disorder
Cognitive Control Emotion Training to Prevent Major Depression in Youth At-Risk
The goal of this clinical trial is to learn if intervention of positive emotion working memory (PEWM), or negative emotion working memory (NEWM), or positive attention bias training (PABT) can prevent major depressive disorder…
- Trial name
- CTE 2019 (NCT04346784)
- Testing
- positive emotion working memory(PEWM) training, negative emtion working memory(NEWM) training, PABT
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Hunan Normal University
Adolescent Athletic Performance, Muscle Strength Development
Effects of Back Squat Exercise with or Without Blood Flow Restriction in Healthy Adolescent Basketball Athletes
The goal of this clinical trial is to assess the effectiveness of Blood Flow Restriction (BFR) training compared to traditional high-intensity training in adolescent basketball players aged 16-18.
- Conditions
- Adolescent Athletic Performance, Muscle Strength Development, Jump Height Improvement, Ground Reaction Force (GRF) Enhancement
- Trial name
- BFR (NCT06684093)
- Testing
- Back squat with Blood flow restriction machine, Back squats
- Where
- Lebanon
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- St Joseph University, Beirut, Lebanon
Control Condition, Intervention Condition
TEPS for At-Risk Youth
The goal of this aim was to conduct a randomized pilot trial evaluating the feasibility and acceptability of the co-created digital mental health program for anxiety among youth with elevated anxiety.
- Trial name
- NCT07660133
- Testing
- Technology Enabled Prevention Services, Library-As-Usual Control Condition
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Northwestern University
Intensive Care Nurses, Bacterial Colonization
Hand Hygiene Compliance and Bacterial Colonization on Personal Belongings
This study aims to examine whether intensive care nurses' hand hygiene practices are related to the presence and amount of bacteria on their frequently used personal belongings, such as mobile phones, pens, and identification…
- Conditions
- Intensive Care Nurses, Bacterial Colonization, Hand Hygiene Compliance
- Trial name
- HHC-BC (NCT07782385)
- Volunteers
- 57 people
- Sponsor
- Uludag University
Severe Bronchopulmonary Dysplasia
PNEUMOSTEM for the Prevention and Treatment of Severe BPD in Premature Infants
This study is to evaluate the efficacy and safety of PNEUMOSTEM® for the Prevention and Treatment of Severe Bronchopulmonary Dysplasia (Severe BPD) in Premature Infants.
- Trial name
- NCT03392467
- Testing
- PNEUMOSTEM
- Where
- 2 sites in South Korea
- Volunteers
- 60 people
- Sponsor
- Medipost Co Ltd.
Landing Biomechanics, Jumping Performance
Effectiveness of Core Training on the Biomechanics of Jump Landing in Amateur Female Basketball Players
The goal of this clinical trial is to evaluate the effectiveness of a core training intervention on jump-landing biomechanics in female amateur basketball players.
- Conditions
- Landing Biomechanics, Jumping Performance, Trunk Stability
- Trial name
- NCT06633237
- Testing
- Core training program in female amateur basketball players
- Where
- Spain
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Injuries, Trauma
Handlebar Grip Related Injury Prevention (GRIP) Study: Are Exposed Metal Handlebar Ends a Risk Factor for Injury?
Cycling injuries are the 3rd most common mechanism of injury in 7-13 year olds[1]. Bicycle injuries have remained one of the commonest causes of paediatric abdominal trauma for over 60 years[2,3].
- Conditions
- Injuries, Trauma, Wounds and Injuries, Children
- Trial name
- GRIP (NCT02378311)
- Volunteers
- 50 people
- Sponsor
- Andrew Neilson
Behavior, Health, Behavior, Smoking
Evaluation of The Stanford Tobacco Prevention Toolkit
The Stanford Tobacco Prevention Toolkit is a free online curriculum developed for use by educators and health professionals in providing tobacco-specific prevention education to middle and high school students.
- Trial name
- NCT04467034
- Testing
- Stanford Tobacco Prevention Toolkit curriculum
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stanford University
Premature Birth
Iron-fortified Parenteral Nutrition in the Prevention and Treatment of Anemia in Premature Infants
The purpose of this study is to determine whether iron-fortified PN is effective in the preventative and treatment of preterm infants. Preterm infants are at risk for anemia especially in preterm infants.
- Trial name
- NCT02743572
- Testing
- iron sucrose-1, iron sucrose-2, iron sucrose-3
- Where
- China
- Volunteers
- 129 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Bacteremia
Prophylactic Antimicrobial Catheter Lock
This is a randomized, double blinded, prospective, multicenter, clinical trial of the use of Heparin versus Gentamicin as a pos-dialysis catheter lock solution.
- Trial name
- ALLOCK (NCT00571259)
- Testing
- Heparin 1000U/mL, 4% Sodium Citrate with Gentamicin 320 mcg/mL
- Where
- United States
- Volunteers
- 303 people
- Sponsor
- Satellite Healthcare
Obesity & Overweight, Eating Disorders
Lifestyle Intervention for Obesity and Eating Disorder Prevention in Transgender Adolescents
Transgender and gender-diverse adolescents are at increased risk for obesity, disordered eating behaviors, body dissatisfaction, and reduced quality of life due to minority stress and structural inequities.
- Conditions
- Obesity & Overweight, Eating Disorders, Body Image Disturbance, Gender Diverse Populations
- Trial name
- NCT07466069
- Testing
- TransForm Health Program
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- University of Sao Paulo
Human Immunodeficiency Virus (HIV), HIV Pre-Exposure Prophylaxis
A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011)
Researchers are looking for new medicines to prevent HIV-1 (Human Immunodeficiency Virus Type 1) infection. The goals of this study are to learn: If taking MK-8527 once a month works to prevent HIV-1 infection as well as or…
- Trial name
- NCT07044297
- Testing
- MK-8527, FTC/TDF
- Where
- 81 sites in United States, Argentina and 14 more
- Volunteers
- 4,390 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Injury;Sports, Biomechanical Lesions
Effectiveness of Basketball Pre-injury Attack Program to Reduce the Susceptibility of Injury in Youth Basketball Players
Basketball is an impact, coordination-opposition sport with continuous contact among players and it is considered a sport of medium-high injury incidence.
- Conditions
- Injury;Sports, Biomechanical Lesions, Musculoskeletal Injury, Sports Physical Therapy
- Trial name
- DPL2 (NCT05256186)
- Testing
- Basketball Pre-injury Attack program
- Where
- Spain
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Hereditary Angioedema (HAE)
Study to Evaluate the Clinical Efficacy and Safety of Subcutaneously Administered C1 Esterase Inhibitor for the Prevention of Angioedema Attacks in Adolescents and Adults With Hereditary Angioedema
The purpose of this study is to assess the efficacy and safety of subcutaneous administration of a liquid formulation of C1 esterase inhibitor for the prevention of angioedema attacks in adolescent and adult subjects with…
- Trial name
- NCT02584959
- Testing
- C1 esterase inhibitor [human] liquid
- Where
- 27 sites in United States, Canada and 5 more
- Volunteers
- 75 people
- Sponsor
- Shire
Mental Disorders
Regulating Emotions Through Adapted Dialectical Behavior Skills for Youth (READY-Nepal)
Published research on the development of mental health symptomatology among adolescents has expanded in recent years and indicates the presence of a growing public health concern.
- Trial name
- READY-Nepal (NCT03807427)
- Testing
- READY-Nepal
- Where
- Nepal
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Brandon A Kohrt, MD, PhD
Myopia, Prevention and Control
Effectiveness of Digital Defocus Vision Training With Low-Concentration Atropine on the Prevention and Control of Myopia in Children: A Clinical Study
Based on existing theories of myopia development and progression, our preliminary work has leveraged the features of virtual reality (VR) technology to digitally simulate myopic defocus signals through image-based emulation.
- Trial name
- NCT07724210
- Testing
- For the experimental group,Virtual reality-based digital defocus training combined with 0.02% atropine eye drops, For the control group, one drop of 0.02% atropine eye drops was instilled into each eye at bedtime daily, combined with full-time wear of fully corrected multi-zone positive optical defocus (DIMS) spe
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Tuberculosis
Evaluation of Safety, Immunogenicity, and Prevention of TB With AERAS-404 and BCG Revaccination in Healthy Adolescents
Randomized, Placebo Controlled, Partially Blinded Phase II Study to Evaluate Safety, Immunogenicity, and Prevention of Infection with Mycobacterium tuberculosis of AERAS-404 and BCG Revaccination in Healthy Adolescents
- Trial name
- NCT02075203
- Testing
- AERAS-404, Bacillus Calmette-Guérin (BCG)
- Where
- 2 sites in South Africa
- Volunteers
- 989 people, healthy volunteers welcome
- Sponsor
- Aeras
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