Clinical trials: Preventive Intervention
E-cigarette Use
Evaluation of the Be Vape Free Curriculum of the Tobacco Prevention Toolkit
The Stanford Tobacco Prevention Toolkit is a free online curriculum developed for use by educators and health professionals in providing tobacco-specific prevention education to middle and high school students.
- Trial name
- NCT05493982
- Testing
- Stanford Vaping Prevention curriculum
- Where
- United States
- Volunteers
- 2,779 people, healthy volunteers welcome
- Sponsor
- Stanford University
Domestic Violence, Mental Health Impairment
Trial of a Multi-pronged Intervention to Address Prevention of Violence in Zambia
This study evaluates the effectiveness of a multi-pronged intervention in reducing and preventing violence against women and children compared to a treatment as usual control group among families living in Lusaka, Zambia.
- Conditions
- Domestic Violence, Mental Health Impairment, Child Abuse, Alcoholism
- Trial name
- NCT02790827
- Testing
- CETA, Treatment as usual
- Where
- Zambia
- Volunteers
- 626 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Depressive Disorder
Neutral and Positive Attention Bias Modification Training for Young Adults With Depressive Symptoms
This study intends to explore the therapeutic effects of the development of negative attention bias modifaction and positive attention bias on depressive symptoms and redundancy through two different attention training methods…
- Trial name
- NCT03971942
- Testing
- Neutral ABMT, Positive ABMT
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Hunan Normal University
Hematologic Malignancy, Myeloid Malignancy
Pediatric Study of GVHD Ppx w/o Calcineurin Inhibitors After Day60 Post First Allo HSCT for Hematological Malignancies.
The participants are being asked to take part in this clinical trial because the participant have a lymphoid or myeloid based cancer diagnosis that requires a bone marrow transplant.
- Trial name
- NCT05579769
- Testing
- Ruxolitinib, Mesna, Anti-thymocyte globulin (ATG)
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- St. Jude Children's Research Hospital
Episodic Migraine
A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic Migraine
A migraine is a moderate to severe headache on one side of the head. A migraine attack is a headache that may be accompanied by throbbing, nausea, vomiting, sensitivity to light and sound, or other symptoms.
- Trial name
- NCT05711394
- Testing
- Atogepant
- Where
- 98 sites in United States, Belgium and 14 more
- Volunteers
- 450 people
- Sponsor
- AbbVie
Mental Illness
Homelessness Prevention: Psychiatric Care With Representative Payeeship
Money management is a neglected issue in maintaining persons with mental illness in the community. This randomized controlled trial (RCT) assessed whether a community-based representative payee program, i.e., money management of…
- Trial name
- NCT00057161
- Testing
- Coordinated Representative Payeeship with Case Management
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Thyroid Disease, Parathyroid Disease
Antimicrobial Prophylaxis in Thyroid and Parathyroid Surgery
The effectiveness of antimicrobial prophylaxis (AMP) for prevention of surgical site infection (SSI) following thyroid and parathyroid surgery remains uncertain.
- Trial name
- Ito-RCT1 (NCT01805856)
- Testing
- PIPC piperacillin sodium, CEZ, cefazolin sodium
- Where
- Japan
- Volunteers
- 2,164 people
- Sponsor
- Ito Hospital
Nurse's Role, Cancer
The Effect of Nurse Health Education and Follow-up Programme on Sun Protection Behaviors of Children
The aim of the study is to determine the effect of nurse health education and follow up program on sun protection behaviors of children.
- Trial name
- NCT04396431
- Testing
- education
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ege University
Severe Asthma, COPD
K-HEALTH in AIR - Barcelona Pilot - Cohort
The study protocol is part of the European (EU) project "Knowledge for improving indoor AIR quality and HEALTH" (K-HEALTHinAIR, 2022-2026 - registry 101057693), which focuses on enhancing our understanding of how poor indoor air…
- Trial name
- NCT06421402
- Testing
- Air quality monitoring at patient's home, Questionnaires: Baseline & every six months, Lung function Testing: Baseline & every six months & during exacerbations
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Institut d'Investigacions Biomèdiques August Pi i Sunyer
Phlebitis
Ointment Therapy and Prevention of Cannulation-Induced Superficial Phlebitis
The aim of this study was to determine the effect of Clobetasol ointment with nitroglycerin ointment on the prevention of superficial phlebitis caused by cannulation.
- Trial name
- OT (NCT04685031)
- Testing
- Nitroglycerin ointment, Clobetasol Topical
- Volunteers
- 110 people
- Sponsor
- Komar University of Science and Technology
Type 1 Diabetes Mellitus
Prevention of Hypoglycaemia With Predictive Insulin Suspend Using Sensor Augmented Insulin Pump in Children
The aim of the study is to prove whether the use of the SmartGuard feature of the MiniMed system significantly reduces hypoglycemic excursions and thus provide proactive protection to the user.
- Trial name
- SportGuard (NCT02179281)
- Testing
- Medtronic MiniMed™ 640G system
- Where
- 2 sites in Israel, Slovenia
- Volunteers
- 100 people
- Sponsor
- University of Ljubljana, Faculty of Medicine
HIV-1-infection
Reversing the Epidemic in Africa With Choices in HIV Prevention (REACH)
Participants will be randomized (1:1) to one of two sequences of a vaginal ring (VR) containing 25mg of dapivirine to be inserted monthly for 24 weeks and 200 mg FTC/300 mg TDF oral tablets taken daily for 24 weeks.
- Trial name
- NCT03074786
- Testing
- Dapivirine, Truvada
- Where
- South Africa
- Volunteers
- healthy volunteers welcome
- Sponsor
- International Partnership for Microbicides, Inc.
Cytokine Release Syndrome
A Study of Itacitinib for the Prevention of Cytokine Release Syndrome Induced by Immune Effector Cell Therapy
"The purpose of this study is to assess the safety and efficacy of oral administration of itacitinib for the prevention of cytokine release syndrome (CRS) in male or female participants aged 12 years or older and who are planning…
- Trial name
- NCT04071366
- Testing
- Itacitinib, Immune effector cell therapy, Yescarta
- Where
- 10 sites in United States
- Volunteers
- 112 people
- Sponsor
- Incyte Corporation
Heart Block, CIED Related Infection
Biomarkers & Infection After Prophylactic Antibiotic in Cardiac Implantable Electronic Device Implantation
Effect of single dose \& intrapocket prophylactic antibiotic to cardiac implantable electronic device-related infection \& biomarkers
- Conditions
- Heart Block, CIED Related Infection, CIED-related Infections, Antibiotic Prophylaxis
- Trial name
- BI-PACED (NCT06448624)
- Testing
- Ampicillin sulbactam 3 days
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Universitas Diponegoro
School Readiness, Developmental Delays
Early Intervention Foster Care: A Prevention Trial
The Early Intervention Foster Care [EIFC] project is an efficacy trial of the Oregon Social Learning Center Multidimensional Treatment Foster Care Program, a preventive intervention that targets 3 commonly co-occurring variables…
- Trial name
- EIFC (NCT00701194)
- Testing
- Early Intervention Foster Care (EIFC)
- Where
- United States
- Volunteers
- 177 people
- Sponsor
- Oregon Social Learning Center
Cytomegalovirus Infections, HIV Infections
A Randomized, Double-Blind Study of the Efficacy and Safety of Oral Ganciclovir for the Prevention of CMV Disease in People Infected With the Human Immunodeficiency Virus
To evaluate the efficacy of oral ganciclovir in preventing progression to cytomegalovirus (CMV) disease (e.g., CMV retinitis, gastrointestinal CMV disease) in CMV-infected people with HIV infection and CD4 lymphocyte counts <=…
- Trial name
- NCT00002095
- Testing
- Ganciclovir
- Where
- 19 sites in United States
- Volunteers
- 700 people
- Sponsor
- Hoffmann-La Roche
Infections, Papillomavirus
Human Papilloma Virus (HPV) Vaccine Efficacy Trial Against Cervical Pre-cancer in Young Adults With GlaxoSmithKline (GSK) Biologicals HPV-16/18
Human Papilloma virus (HPV) are viruses that cause a common infection of the skin and genitals in men and women. Several types of HPV infection are transmitted by sexual activity and, in women, can infect the cervix (part of the…
- Trial name
- NCT00122681
- Testing
- Cervarix™, Havrix™-based investigational formulation
- Where
- 138 sites in United States, Australia and 12 more
- Volunteers
- 18,729 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Diaper Dermatitis
Neonatal Intensive Care Unit (NICU) Diaper Dermatitis: Prevention and Treatment With Airtime
The purpose of this study is to investigate the use of 3-5 minutes air therapy for the prevention and treatment of diaper dermatitis in infants 30 weeks and older receiving care in the neonatal intensive care unit (NICU).
- Trial name
- NCT06958003
- Testing
- Air Therapy
- Where
- United States
- Volunteers
- 320 people
- Sponsor
- TriHealth Inc.
Healthy Participants
Randomized Controlled Trial of ADAPT
This trial examines the effectiveness of a novel neurodevelopmentally informed intervention - Adolescent Developmentally-Appropriate health Promotion Therapy (ADAPT) - on preventing alcohol use and promoting well-being among…
- Trial name
- NCT07132866
- Testing
- ADAPT
- Where
- Denmark
- Volunteers
- 1,000 people
- Sponsor
- University of Aarhus
Hiv, Adolescent Behavior
A Pragmatic Trial of An Adaptive eHealth HIV Prevention Program for Diverse Adolescent MSM
This pragmatic trial of an HIV prevention program focuses on HIV risk-reduction in men who have sex with men (MSM) ages 13-18. The design is a three-tiered, internet-based HIV prevention intervention series that uses a sequential…
- Conditions
- Hiv, Adolescent Behavior, Sex, Safe
- Trial name
- SMART (NCT03511131)
- Testing
- Queer Sex Ed, Keep It Up, Keep It Up-Control
- Where
- United States
- Volunteers
- 1,306 people, healthy volunteers welcome
- Sponsor
- Northwestern University
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