Clinical trials: Prognostic Model
Gastric Cancer (GC)
Development and Validation of the Surgical Assessment and Healthcare (SAH) Index for Gastric Cancer Treatment Evaluation
This study develops the Surgical Assessment and Healthcare (SAH) Index, a new tool to fairly evaluate gastric cancer surgery outcomes.
- Trial name
- SAH (NCT07180966)
- Where
- China
- Volunteers
- 780 people
- Sponsor
- Ruijin Hospital
Hypertension
Prognostic Model of Hypertension
The aim of this study was to establish a registration and monitoring system for hypertension in Xinjiang from 2020 to 2030 to obtain real information about patient basic information, patient characteristics, diagnostic test…
- Trial name
- PHOP-HT (NCT06160921)
- Testing
- Standard therapy
- Where
- China
- Volunteers
- 50,000 people
- Sponsor
- Xinjiang Medical University
Emergency Care, Clinical Decision Support
Artificial Intelligence(AI) in the Emergency Department (ED) in Cologne
This retrospective, non-interventional study evaluates the prognostic performance of open-weight Large Language Models (LLMs) in the setting of a German academic emergency department.
- Conditions
- Emergency Care, Clinical Decision Support, Triage
- Trial name
- KINA-CO (NCT07725965)
- Where
- Germany
- Volunteers
- 100,000 people
- Sponsor
- University of Cologne
Neoplasms Pancreatic
A New Prognostic Score Model for Pancreatic Ductal Adenocarcinoma
The AJCC TNM staging system is the prevailing method in prognostic evaluation of pancreatic ductal adenocarcinoma (PDAC) at present , but it did not include factors such as the tumor immune microenvironment that are known to…
- Trial name
- NCT05547074
- Testing
- pancreatic cancer surgery
- Where
- China
- Volunteers
- 302 people
- Sponsor
- Zhejiang University
Traumatic Brain Injury (TBI)
Prognostic Model for Predicting Outcome After Moderate to Severe Paediatric Traumatic Brain Injury
Due to ethical and logistical challenges related to paediatric research, there is limited age-appropriate evidence for managing paediatric traumatic brain injury (pTBI).
- Trial name
- PROMPT (NCT07538440)
- Where
- United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Advanced Solid Tumors Cancer, Hospitalizations
Biological Age Predicts 90-Day Mortality in Advanced Cancer
This retrospective study evaluates whether biological age, calculated using the PhenoAge model, predicts short-term outcomes in patients with advanced cancer who were hospitalized.
- Trial name
- BIOAGE-CAN (NCT07035470)
- Testing
- PhenoAge-Based Biological Age Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 1,615 people
- Sponsor
- Ankara Etlik City Hospital
Duodenal, Gastrointestinal Stromal Tumors
Development and External Validation of a Prognostic Model for DFS After Curative Resection of Duodenal GIST
Gastrointestinal stromal tumour (GIST) is the most common mesenchymal neoplasm of the digestive tract, originating from the interstitial cells of Cajal.
- Trial name
- NCT07837271
- Where
- 2 sites in China
- Volunteers
- 288 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Gastric Cancer
Hematological Dynamic Scores for Predicting Survival and Treatment Response for Advanced Gastric Cancer After Neoadjuvant Therapy
HMDLS, based on hematological markers, could effectively distinguish the long-term efficacy of AGC patients after NAT. The predictive performance of nomogram-HMDLS was better than ypTNM stage, achieving better prognostic…
- Trial name
- NCT06573307
- Where
- China
- Volunteers
- 442 people
- Sponsor
- Chang-Ming Huang, Prof.
Spinal Cord Injuries (SCI)
A Rehabilitation Data Collection Study in Patients With Spinal Cord Injury
The goal of this observational study is to build a rehabilitation registry for people with spinal cord injury (SCI) in Korea and to create foundational data for predicting patients' long-term function.
- Trial name
- NCT07901985
- Where
- South Korea
- Volunteers
- 250 people
- Sponsor
- Seoul National University Hospital
Oncology
Assessing Perceptions of ML Explanations by Medical Oncologists
The objective of this proposal is to conduct a vignette-based survey among practicing oncology clinicians who treat non-small cell lung cancer to assess the trustworthiness of explainable predictions from a neurosymbolic AI vs.
- Trial name
- NCT06699615
- Testing
- Once time de-identified Qualtrics survey
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
CMT, CMT (Charcot Marie Tooth Disease)
A Multi-omic Approach to the Identification of Novel Biomarkers in Early Charcot-Marie-Tooth 1A Disease (CMT1A)
The most common inherited neuropathy is Charcot-Marie-Tooth disease type 1A (CMT1A), caused by a duplication of the gene expressing PMP22.
- Conditions
- CMT, CMT (Charcot Marie Tooth Disease), CMT - Charcot-Marie-Tooth Disease, CMT1A
- Trial name
- CMT-MODs (NCT07476365)
- Where
- Germany
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen
Traumatic Brain Injury
Transforming Research and Clinical Knowledge in TBI Pilot
The global aim of this proposal is to test and refine Common Data Elements (CDEs), neuroimaging standards, and best practices for genetics and proteomics in Traumatic Brain Injury (TBI) studies.
- Trial name
- NCT01565551
- Testing
- N/A (Observational Study)
- Where
- 4 sites in United States
- Volunteers
- 650 people
- Sponsor
- University of California, San Francisco
Acute Liver Failure
Etiology and Prognostic Factors in Patients With Acute Liver Failure
Acute liver failure (ALF) is a rare but life-threatening condition with high mortality. Despite advances in supportive care and liver transplantation, prognosis varies significantly across etiologies, particularly in patients…
- Trial name
- NCT07556055
- Volunteers
- 400 people
- Sponsor
- Li-Ying Sun
Mycosis Fungoides, Non-Hodgkin's Lymphoma
ID Of Prognostic Factors In Mycosis Fungoides/Sezary Syndrome
The purpose of the study is to develop a prognostic index model for the rare disease of mycosis fungoides and sezary syndrome. This will be done by collecting standardized clinical data at various institutions.
- Trial name
- NCT02848274
- Where
- 13 sites in United States, Argentina and 5 more
- Volunteers
- 2,000 people
- Sponsor
- Stanford University
Gliomas Harboring IDH1 and/or IDH2 Mutations, Glioma Glioblastoma Multiforme
Multicenter Prospective Study on MRI AI Model for Midline Glioma Subtyping and Prognosis:
A vision-language model using preoperative MRI and clinical variables has been developed to simultaneously predict three key molecular markers in midline gliomas: H3K27M, IDH, and 1p/19q.
- Conditions
- Gliomas Harboring IDH1 and/or IDH2 Mutations, Glioma Glioblastoma Multiforme, Glioma of Brainstem, Glioma, Diffuse Midline, H3K27M-mutant
- Trial name
- NCT07608003
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Xiangya Hospital of Central South University
Pulmonary Atresia With Intact Ventricular Septum, Congenital Heart Disease
Prognostic Model of Postnatal Circulation in Pulmonary Atresia-critical Stenosis With Intact Ventricular Septum
Pulmonary atresia (PA)/critical stenosis (CS) with intact ventricular septum (PA/CS-IVS) is a rare congenital heart disease (CHD), that presents heterogeneously.
- Conditions
- Pulmonary Atresia With Intact Ventricular Septum, Congenital Heart Disease, Fetal Cardiac Disorder
- Trial name
- NCT07095829
- Testing
- No intervention
- Where
- 2 sites in Spain, Sweden
- Volunteers
- 150 people
- Sponsor
- Hospital Universitario 12 de Octubre
Hepatocellular Carcinoma
The AI Prognostic Assessment and Pathological Basis Research of Early HCC After Minimally Invasive Treatment
The study evaluates artificial intelligence method based on multimodal magnetic resonance imaging (MRI) images and clinical data in preoperative prediction of prognosis in early hepatocellular carcinoma (HCC) patients treated…
- Trial name
- NCT04299919
- Testing
- Minimally invasive treatment, Hepatectomy
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Multiple Myeloma
Cohort Construction and Prognostic Model Construction for Multiple Myeloma
Multiple myeloma (MM) is a disease caused by malignant plasma cell proliferation disorder. Survival outcomes continue to vary widely even within uniformly treated clinical trial populations.
- Trial name
- NCT06366802
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Sepsis
A Prognostic Model Based on POCUS at ICU Admission in Critically Ill Patients With Sepsis
Sepsis is responsible for one in three patient deaths. Understanding the severity of the disease, directing medications, prognosticating, and communicating with family members depend on the ability to predict outcomes in a…
- Trial name
- NCT06082154
- Testing
- ultrasound
- Where
- Nepal
- Volunteers
- 175 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Rhabdomyolysis
Pediatric Rhabdomyolysis in the Pediatric Intensive Care Unit: A Retrospective Cohort Study
This retrospective observational cohort study aims to evaluate the clinical characteristics, causes, intensive care management, and outcomes of pediatric patients with rhabdomyolysis admitted to the Pediatric Intensive Care Unit…
- Trial name
- NCT07851987
- Where
- Germany
- Volunteers
- 55 people
- Sponsor
- Hannover Medical School