Clinical trials: Prolonged Mechanical Ventilation
Mechanical Ventilation
Retrospective Study on Prolonged Sedation Effects With Inhaled Agents in PICU
The objective of the study is to evaluate the effects of halogenated gases on sedation and analgesia, to describe the tolerance and to determine the risk factors for failure, in pediatric intensive care patients during prolonged…
- Trial name
- RESPIRE (NCT05064592)
- Where
- 2 sites in France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Critically Ill
Towards RECOVER: Outcomes and Needs Assessment in Intensive Care Unit (ICU) Survivors of Prolonged Mechanical Ventilation and Their Caregivers
Advances in critical care medicine have dramatically improved the survival of critically ill patients requiring prolonged mechanical ventilation.
- Trial name
- RECOVER (NCT00896220)
- Where
- 5 sites in Canada
- Volunteers
- 500 people
- Sponsor
- University Health Network, Toronto
Prolonged Mechanical Ventilation
Application of Early Bundle Management of Mechanical Ventilation to Prevent Ventilator Dependence in Children
This study is based on the risk factors of previous studies to formulate a bundle treatment plan to prevent ventilator dependence in children, in order to reduce the proportion of ventilator dependence in children and provide a…
- Trial name
- NCT06125210
- Testing
- early bedside rehabilitation, nutrition program, tracheotomy
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Children's Hospital of Fudan University
Mechanical Ventilation
Study of Muscle Effects of BYM338 in Mechanically Ventilated Patients
The purpose of this study is to evaluate the effect of BYM338 on muscle mass and function in Group III failure to wean patients, as compared to placebo controls.
- Trial name
- NCT01868685
- Testing
- BYM338
- Sponsor
- Novartis Pharmaceuticals
Critical Illness
Determination of Risk Factors and Mortality for Pediatric Chronic Critical Illness in Turkey
It is predicted that the number of Pediatric Chronic Critical Illness increases similar to adult all over the world. The prevalence of Pediatric Chronic Critical Illness in Turkey is unknown.
- Trial name
- NCT03308513
- Where
- Turkey (Türkiye)
- Volunteers
- 888 people
- Sponsor
- Yuzuncu Yil University
Premature Birth, Respiration Failure
Predictors of Prolonged Mechanical Ventilation in Preterm Infants
This prospective cohort study aims to identify the independent predictors of prolonged mechanical ventilation in preterm infants admitted to the Neonatal Intensive Care Unit of Assiut University Children Hospital.
- Conditions
- Premature Birth, Respiration Failure, Bronchopulmonary Dysplasia
- Trial name
- NCT07821632
- Volunteers
- 100 people
- Sponsor
- Assiut University
Mechanical Ventilator Weaning, Respiratory Muscle Training
Muscle Recruitment During Neck Flexion and Inspiratory Muscle Training
Respiratory muscle dysfunction is highly prevalent in patients with prolonged weaning from mechanical ventilation and is strongly associated with weaning failure.
- Trial name
- FLEX (NCT05710432)
- Testing
- Quasi-Isometric Neck Flexion, Inspiratory Muscle Training
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Unity Health Toronto
Preterm Birth
Repercussions of Respiratory Physiotherapy in Preterm Infants Under Mechanical Ventilation
Respiratory diseases are a major morbidity and mortality causes of neonatal requiring mechanical ventilation, especially in newborn preterm infants (PN), thus respiratory therapy becomes increasingly necessary in order to…
- Trial name
- preterm (NCT03159039)
- Testing
- Conventional Physiotherapy, Prolonged slow exhalation technique
- Volunteers
- 43 people
- Sponsor
- Universidade Cidade de Sao Paulo
Prolonged Mechanical Ventilation in Pediatric Intensive Care Unit
LongVentKids Study
Scientific advances, population growth, lower mortality, and increasing complexity of diseases have boosted up the number of patients requiring prolonged breathing assistance with mechanical ventilators in the pediatric intensive…
- Trial name
- LVK (NCT04112459)
- Testing
- prolonged mechanical ventilation
- Where
- Canada
- Volunteers
- 6,000 people
- Sponsor
- St. Justine's Hospital
Outcome
Outcome and Predictors of Mortality of Patients on Prolonged Mechanical Ventilation
Prolonged mechanical ventilation (PMV) and weaning failure are factors associated with prolonged hospital length of stay and increased morbidity and mortality.
- Trial name
- NCT06087939
- Testing
- Mechanical ventilation
- Volunteers
- 323 people
- Sponsor
- Wollo University
Prolonged Mechanical Ventilation
Epidemiological Survey of Children With Prolonged Mechanical Ventilation.
Mechanical ventilation is an effective treatment for respiratory failure, no more than ten percent of patients with respiratory failure need long-term mechanical ventilation.
- Trial name
- NCT04511741
- Testing
- no intervention, it is an observational study.
- Where
- China
- Volunteers
- 346 people
- Sponsor
- Children's Hospital of Fudan University
Mechanical Ventilation Complication
Mechanical Ventilator Weaning in Chronically Ventilated Patients
Mechanical ventilation is a commonly used life-saving hospital procedure for patients with severe breathing difficulty. Some patients have difficulty separating from the ventilator and need to be removed gradually.
- Trial name
- NCT06976554
- Testing
- weaning
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of California, Los Angeles
Mechanical Ventilation
Prognostic Estimates Among ICU Clinicians
One challenge with decision making for mechanically ventilated is that their prognosis is often uncertain. The ProVent-14 score incorporates clinical variables measured on the 14th day of mechanical ventilation to predict risk of…
- Trial name
- NCT06452797
- Testing
- ProVent-14 score
- Where
- 3 sites in United States
- Volunteers
- 238 people
- Sponsor
- Rush University Medical Center
Pediatric Liver Transplantation
Incidence and Risk Factors of Prolonged Post-Operative Mechanical Ventilation
The primary goal of the study is to identify incidence and risk factors for PPMV in pediatric patients undergoing liver transplantation.
- Trial name
- NCT05825703
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Critical Illness
Specialized Treatment, Rehabilitation and Outcome in Patients With Prolonged Critical Illness
This prospective observational study aims to describe the outcome for patients with persistent or chronic critical illness treated at Remeo, a clinic specialized for patients in need of prolonged intensive care and intensive care…
- Trial name
- CritillPro (NCT04247607)
- Where
- Sweden
- Volunteers
- 250 people
- Sponsor
- Remeo AB
Mechanical Ventilation, Surgeries Undergoing General Anesthesia
Preoperative Characteristics and Outcomes of Neonates Undergoing Surgical Procedures in the NICU
This retrospective observational study evaluates neonates who underwent surgical procedures during admission to a neonatal intensive care unit (NICU).
- Trial name
- NeoSurg-Resp (NCT07793812)
- Testing
- Surgical Procedures
- Where
- Turkey (Türkiye)
- Volunteers
- 183 people
- Sponsor
- Ayberk Ozkavakli