Clinical trials: Prophylaxis
Gastric or Duodenal Ulcers
Long-term Use of Takepron on the Prevention of Recurrence of Gastric/Duodenal Ulcer in Patients Receiving Non-steroidal Anti-inflammatory Drugs
The purpose of this study is to investigate the safety and efficacy of long-term administration of lansoprazole (Takepron) therapy for up to 12 months in the routine clinical setting in patients receiving oral non-steroidal…
- Trial name
- NCT02099708
- Testing
- Lansoprazole
- Volunteers
- 3,502 people
- Sponsor
- Takeda
Hip Fractures, Prevention
Prevention of Hip Fractures With Soft and Hard Hip Protectors
The aim of this study is to compliance with and effect of soft and hard hip protectors in Norwegian nursing homes.
- Trial name
- NCT00397410
- Testing
- Hip protectors
- Where
- Norway
- Volunteers
- 1,236 people
- Sponsor
- Norwegian Institute of Public Health
Disability Physical, Developmental Disability
Virtual Reality Exercise in a Community Highschool for Children With Disabilities
The purpose of this study is to work with a community engagement group to develop and pilot a protocol for a virtual reality exergaming program for children with special needs at a high school.
- Conditions
- Disability Physical, Developmental Disability, Physical Inactivity
- Trial name
- NCT05935982
- Testing
- Virtual reality exercise
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Fruit and Vegetable Consumption in Children
Kokkerelli Learning Street Effect Evaluation
In 2012, the Kids University for Cooking Foundation BV has developed a nutrition education programme called 'Kokkerelli Learning Street'.
- Trial name
- NCT04190680
- Testing
- Kokkerelli Learning Street
- Where
- Netherlands
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Body Image Disturbance, Disordered Eating Behaviors
Adolescent Chatbot
The purpose of this study is to test an eating disorders prevention digital chatbot program in a diverse group of adolescents.
- Conditions
- Body Image Disturbance, Disordered Eating Behaviors, Eating Disorder Prevention
- Trial name
- EMBody (NCT07094503)
- Testing
- Wysa Digital Chatbot Program
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Washington University School of Medicine
Malaria
Innovative Intermittent Preventive Treatment Approaches to Reduce Malaria Burden in School-age Children in Burkina Faso
This will be an open label cluster randomized study with two active intervention and one control arm. A cluster will be defined as a selected village.
- Trial name
- BF-IPTsc (NCT05946642)
- Testing
- Sulphadoxine-Pyrimethamine/Amodiaquine, Dihydroartemisinin/Piperaquine (DP) plus Ivermectin (IVM)
- Where
- Burkina Faso
- Volunteers
- 13,000 people
- Sponsor
- Malaria Consortium
Prophylaxis of Ross River Virus Infection
Ross River Virus (RRV) Vaccine Study
The purpose of the study is to verify the safety and adequacy of the immune response produced by a 2.5 µg, adjuvanted (aluminium hydroxide) dose of Ross River Virus (RRV) vaccine and to demonstrate the consistency of manufacture…
- Trial name
- NCT01242670
- Testing
- Ross River Virus Vaccine
- Where
- 17 sites in Australia
- Volunteers
- 1,968 people, healthy volunteers welcome
- Sponsor
- Alachua Government Services, Inc.
Wounds and Injuries
Strength Training for Injury Prevention
The purpose of this study is to explore the effects of a strength \& conditioning (S \& C) program on risk factors for injury (Y-balance and Functional Movement Screen scores), as well as parent reported injury occurrence in…
- Trial name
- NCT02927418
- Testing
- Strength & Conditioning, Control
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Health Promotion and Obesity Prevention
The Wildcat Wellness Coaching Trial
Female children (aged 8-13 years) will be recruited through posted flyers, newspaper ads, and word of mouth in the Manhattan, KS area.
- Trial name
- NCT01845480
- Testing
- Wellness coaching
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Kansas State University
Depressive Symptoms
Internet-based Program for Prevention and Early Intervention of Adolescent Depression
Background: Depression is prevalent and can have devastating effects on the life of adolescents. Computerized intervention programs for depression have shown positive results.
- Trial name
- NCT03521388
- Testing
- Take care of your mood (CUIDA TU ANIMO in Spanish), Control
- Where
- Chile
- Volunteers
- 947 people
- Sponsor
- University of Chile
Graft Versus Host Disease
Alefacept for Prevention of Graft Versus Host Disease (GVHD)
Alefacept (AMEVIVE®) is an immunosuppressive dimeric fusion protein. It was shown to interfere with lymphocyte activation by specifically binding to the lymphocyte antigen, CD2, and inhibiting LFA-3/CD2 interaction.
- Trial name
- NCT00361413
- Testing
- Alefacept (AMEVIVE®), control group
- Where
- Israel
- Volunteers
- 26 people
- Sponsor
- Hadassah Medical Organization
Tobacco Prevention
A Pilot RCT on the Feasibility of an Online Quiz Game to Promote Tobacco-related Knowledge, Attitudes and Behaviours Among Primary School Students
The goal of this pilot RCT is to test the feasibility of an online quiz game to promote tobacco-related knowledge, attitudes and behaviours in local primary 5-6 school students.
- Trial name
- NCT06812962
- Testing
- Online quiz competition
- Where
- Hong Kong
- Volunteers
- 921 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Malaria, Falciparum
Study of the Impact of Intermittent Preventive Treatment in Schools on Malaria, Anaemia and Education.
This study seeks to establish whether intermittent preventive treatment (IPT) can reduce malaria among school-going children and its consequent impact on school performance.
- Trial name
- NCT00142246
- Testing
- Intermittent preventive treatment (SP and amodiaquine)
- Where
- Kenya
- Volunteers
- 6,758 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Congenital Heart Disease
Imaging by 4 DFlow in Patients With Tetralogy of Fallot
Conventionnal cadiac magnetic resonance (CMR) is the reference to assess changes in right heart flow and pulmonary artery hemodynamics in patients with repaired Tetralogy of Fallot.
- Trial name
- 4DFlowFallot (NCT03542968)
- Testing
- magnetic resonance imaging
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Infant, Very Low Birth Weight, Infant, Premature
Trial of Indomethacin Prophylaxis in Preterm Infants (TIPP)
This trial was to determine whether giving low-dose indomethacin to infants weight 500 to 999 grams (approximately 1 to 2 pounds) at birth improves their survival without cerebral palsy or developmental problems at 18 to 22…
- Conditions
- Infant, Very Low Birth Weight, Infant, Premature, Ductus Arteriosus, Patent
- Trial name
- TIPP (NCT00009646)
- Testing
- indomethacin
- Where
- 9 sites in United States
- Volunteers
- 1,202 people
- Sponsor
- NICHD Neonatal Research Network
Malaria
Evaluation of the Public Health Impact of Seasonal Intermittent Preventive Treatment (IPT) in Children in Senegal
In areas of seasonal malaria transmission the burden of severe disease and mortality due to malaria is mainly among children under 5 years of age.
- Trial name
- NCT00712374
- Testing
- sulfadoxine-pyrimethamine plus amodiaquine
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Upper Respiratory Tract Infection
Montelukast as Prophylaxis for Upper Respiratory Tract Infections in Children: a Randomised, Double-blind, Placebo-controlled Study
Viral upper respiratory tract infection (URI) is one of the most common diseases among toddlers and pre-school children.Complete and effective prevention measures for URI are currently unavailable.
- Trial name
- NCT00551382
- Testing
- Muntelukast
- Where
- 3 sites in Israel
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Street-crossing Ability, Pedestrian Safety
Using Virtual Reality to Train Children in Pedestrian Safety
Pedestrian injuries are among the leading causes of morbidity and mortality in American children ages 7-8, but existing behavior-oriented interventions achieve only modest success.
- Trial name
- NCT00850759
- Testing
- virtual pedestrian environment, computer and video, streetside training
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
HIV (Human Immunodeficiency Virus), Continuum of Care
Adaptation and Implementation of an Evidence-based Approach to Advance HIV Prevention and Care
Transgender women in the intervention condition will attend TransAction individual risk reduction sessions; skill building and open group support sessions, and social events between baseline and 3-month assessment.
- Conditions
- HIV (Human Immunodeficiency Virus), Continuum of Care, Stigma
- Trial name
- NCT07495059
- Testing
- TransAction
- Where
- Vietnam
- Volunteers
- 80 people
- Sponsor
- University of California, Los Angeles
Leprosy
Bedaquiline Enhanced Post ExpOsure Prophylaxis for Leprosy (Phase 2)
This study will evaluate a combination of bedaquiline and rifampicin as post exposure prophylaxis (PEP) for leprosy in Comoros. It will be a follow-up to the PEOPLE trial on PEP with rifampicin, which is ending in 2022.
- Trial name
- BE-PEOPLE P2 (NCT05406479)
- Testing
- BE-PEP (Bedaquiline), SDR-PEP, BE-PEP (Rifampicine)
- Where
- Comoros
- Volunteers
- 313 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
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