Clinical trials: Prostate
Prostate Cancer
Trial of IV Injection of CV787 in Hormone Refractory Metastatic Prostate Cancer
This is a multi-center, open-label, dose finding study of CV787 adenovirus in patients with hormone refractory metastatic prostate cancer.
- Trial name
- NCT00116155
- Testing
- CV787 (CG7870)
- Sponsor
- Cell Genesys
Breast Cancer, Prostate Cancer
Eligibility Screening for the NIH Intramural Research Program Clinical Protocols
The purpose of this protocol is to provide patients with adequate informed consent to understand that screening tests with minimal health risk will be performed to evaluate their eligibility for a research study.
- Conditions
- Breast Cancer, Prostate Cancer, Lung Cancer, Sarcoma
- Trial name
- NCT00026754
- Where
- United States
- Volunteers
- 19,522 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Prostate Cancer
Clinical Trial to Study Quality of Life in Prostate Cancer Patients by Randomizing Anti-androgen Versus Total Androgen Blockage Prior to Curative Intended Radiation Therapy
Phase III clinical trial to study quality of life in prostate cancer patients by randomizing anti-androgen versus total androgen blockage prior to curative intended radiation therapy.
- Trial name
- NCT02382094
- Testing
- Bicalutamide
- Volunteers
- 110 people
- Sponsor
- Karolinska University Hospital
Pancreatic Cancer, Osteosarcoma
BLESSED: Expanded Access for DNG64-CAR-V for Advanced Pancreatic Cancer, Sarcoma and Carcinoma of Breast
Forty patients with pancreatic cancer, sarcoma and carcinoma of breast will receive DNG64-CAR-V intravenously or intratumorally at a dose of 1-4 x 10e11 colony forming units (cfu) or equivalent 1.0-6.0 x 10e10 Vector Copies (VC)…
- Conditions
- Pancreatic Cancer, Osteosarcoma, MPNST (Malignant Peripheral Nerve Sheath Tumor), Chondrosarcoma
- Trial name
- NCT04091295
- Testing
- DNG64-CAR-V
- Where
- United States
- Sponsor
- Aveni Foundation
Urinary Incontinence, Prostate Cancer
Perioperative Post-Prostatectomy Incontinence Home Telehealth Program
Many men develop urine leakage after prostate cancer surgery. Usually it is temporary, but pelvic floor muscle training and exercise (including urine control strategies) have been shown to reduce the time to regaining urine…
- Trial name
- ProsTel (NCT01960998)
- Testing
- Pelvic Floor Muscle Training, Perioperative Care and Wetness Management
- Where
- 3 sites in United States
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Prostate Cancer
Positron Emission Tomography in Prostate Cancer
RATIONALE: Diagnostic procedures, such as positron emission tomography using carbon-11 acetate, may help find metastases from prostate cancer and may help predict whether prostate cancer will come back after treatment.
- Trial name
- NCT00121212
- Testing
- carbon-11 acetate PET scan
- Where
- United States
- Volunteers
- 179 people
- Sponsor
- Washington University School of Medicine
Prostate Cancer Metastatic
Radiotherapy to Consolidate Systemic Response in Metastatic Prostate Cancer (ANCHOR-Prostate)
This will be a pragmatic, phase II, registry-based cohort-multiple randomized controlled trial (cmRCT) embedded within an ongoing prospective cancer radiotherapy registry.
- Trial name
- ANCHORProstate (NCT05457699)
- Testing
- Metastasis directed radiotherapy (MDRT), no MDRT
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Prostate Cancer
APC8015 and Bevacizumab in Treating Patients With Prostate Cancer
Phase II trial to study the effectiveness of APC8015 combined with bevacizumab in treating patients who have undergone radiation therapy and/or surgery and who have progressive prostate cancer.
- Trial name
- NCT00027599
- Testing
- bevacizumab, prostatic acid phosphatase-sargramostim fusion protein, sipuleucel-T
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- National Cancer Institute (NCI)
Prostate Cancer
Focused Stereotactic Radiation Treatment of Prostatic Adenocarcinoma
Focused stereotactic radiation treatment of localized prostatic adenocarcinoma. in order to quantify the delay between the focused treatment and the salvage procedure.
- Trial name
- NCT03284151
- Testing
- Cyberknife
- Where
- Luxembourg
- Volunteers
- 26 people
- Sponsor
- Centre Francois Baclesse, Luxembourg
Prostatic Hyperplasia
Safety Profile of Secotex ® in Patients With Benign Prostatic Hyperplasia
The Objective of this study is to conduct a Prescription Event Monitoring (PEM) involving patients treated with Secotex® (Tamsulosin) in "real life" settings.
- Trial name
- NCT02245529
- Testing
- Tamsulosin
- Volunteers
- 982 people
- Sponsor
- Boehringer Ingelheim
Prostate Cancer
The BIOPRES Trial: Transrectal BIOpsies of the PRostate: End Versus Side-firing
The purpose of this study is to study the difference in prostate cancer between two prostate biopsy techniques, namely end-firing and side-firing. These differ in the angle at which the prostate is biopsied.
- Trial name
- BIOPRES (NCT00851292)
- Testing
- TRUS probe
- Where
- Netherlands
- Volunteers
- 800 people
- Sponsor
- Amphia Hospital
Benign Prostatic Hyperplasia
Optilume BPH Catheter System in Benign Prostatic Hyperplasia (BPH)
A post-marketing study using Optilume Catheter System for benign prostatic hyperplasia.
- Trial name
- SUMMIT (NCT05567666)
- Testing
- Optilume Catheter System
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Dean Elterman
Prostate Cancer, PSA
Prostate Biopsy, Transrectal vs. Transperineal: Efficacy and Complications
This study evaluates the difference between 2 prostate biopsy methods, transrectal (through the rectal wall) and transperineal (through the skin) needle biopsy.
- Conditions
- Prostate Cancer, PSA, Infection
- Trial name
- ProBE-PC (NCT04081636)
- Testing
- Systematic Transrectal biopsy (TR-Bx), Targeted Transrectal biopsy (TR-Bx), Systematic Transperineal biopsy (TP-Bx)
- Where
- United States
- Volunteers
- 840 people
- Sponsor
- Albany Medical College
Prostate Cancer
Intraprostatic MAXimal Simultaneous Boost
This trial uses a type of radiotherapy called intensity modulated radiotherapy (IMRT), which is able to deliver the radiation to the prostate while delivering less dose to the surrounding normal organs compared with standard 3D…
- Trial name
- NCT00798837
- Testing
- Intraprostatic maximal simultaneous boost
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- British Columbia Cancer Agency
Prostate Cancer
Testing the Helpfulness of 2 Decision Aids for Prostate Cancer
The purpose of this study is to test different methods for communicating information about prostate cancer treatment to men. The investigators are studying how best to present information so men can make informed decisions about…
- Trial name
- NCT00432601
- Testing
- type of decision aid
- Where
- 4 sites in United States
- Volunteers
- 1,028 people
- Sponsor
- VA Office of Research and Development
Carcinoma Prostate
Multiparametric Assessment of Bone Response in mCRPC Patients Treated With Cabozantinib
Multiparametric assesment of bone response in mCRPC patients treated with Cabozantinib upon progression to chemotherapy and next generation hormonal agents: a phase II study
- Trial name
- MERIDIAN (NCT05265988)
- Testing
- Cabozantinib
- Where
- Italy
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Alfredo Berruti
Simulation Study on Urethral Catheter Traction for Postoperative Hemorrhage Control After TURP
Development and Pilot Evaluation of a Urethral Catheter Traction Device for Post-TURP Hemorrhage Control
Benign prostatic hyperplasia (BPH) is a common condition among elderly men. Transurethral resection of the prostate (TURP) is the gold standard surgical procedure, but postoperative bleeding is a frequent complication.
- Trial name
- NCT07287488
- Testing
- Innovative Urethral Catheter Traction Device, Routine Urethral Catheter Traction
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Bone Cancer, Bone Tumor
A Dose Finding Study to Treat Bone Tumor(s)
To determine the Maximum Tolerated Dose (MTD) of CycloSam®, Samarium-153-DOTMP (Sm-153-DOTMP), a radiopharmaceutical that delivers radiation to the bone when injected, given as a tandemly administered pair of doses to subjects…
- Conditions
- Bone Cancer, Bone Tumor, Solid Tumor, Metastatic Cancer to the Bone
- Trial name
- NCT06008483
- Testing
- 153-Sm-DOTMP (Samarium-153-DOTMP)
- Where
- 4 sites in United States
- Volunteers
- 5 people
- Sponsor
- QSAM Therapeutics, Inc.
Prostate Hyperplasia
Inflammatory Markers: HOLEP Versus TURP
Aim of the study is to compare the systemic inflammatory markers and surgical stress response in patients undergoing HOLEP or TUR-P surgery.
- Trial name
- NCT05108662
- Testing
- Surgery method
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Adana City Training and Research Hospital
Benign Prostatic Hyperplasia, Ejaculation
Factors Predicting The Success of Ejaculation Sparing Transurethral Resection of Prostate in Benign Prostatic Hyperplasia Patients
evaluate the factors predicting the success of ejaculation-sparing TURP in patients with BPH after surgery, in terms of voiding improvement and preserved ejaculation post-operatively.
- Trial name
- NCT07513896
- Testing
- ejaculatory preserving TURP
- Where
- Egypt
- Volunteers
- 108 people
- Sponsor
- Ain Shams University