Clinical trials: Prostate Cancer
Metastatic Cancer, Prostate Cancer
Docetaxel and Imatinib Mesylate in Treating Patients With Androgen-Independent Prostate Cancer and Bone Metastases That Progressed on the Docetaxel and Placebo Group of MDA-ID-030008
RATIONALE: Drugs used in chemotherapy such as docetaxel work in different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00084825
- Testing
- Docetaxel, Imatinib mesylate
- Where
- 3 sites in United States
- Volunteers
- 23 people
- Sponsor
- M.D. Anderson Cancer Center
Prostate Cancer
PROFIT - Prostate Fractionated Irradiation Trial
This trial is designed to determine whether an 8-week course of escalated dose conformal radiation can be compressed safely, and with similar efficacy into a 4-week course.
- Trial name
- NCT00304759
- Testing
- 7800 cGy/39 fractions in 8 weeks, 6000 cGy/20 fractions in 4 weeks
- Where
- 25 sites in Australia, Canada and 1 more
- Volunteers
- 1,204 people
- Sponsor
- Ontario Clinical Oncology Group (OCOG)
Localized Prostate Cancer
Hypofractionated Post-prostatectomy Radiotherapy (HYPORT)for Localized Prostate Cancer
The aim of this trial is to compare the safety outcomes of Hypofractionated postprostatectomy radiotherapy (HYPORT) and Conventionally fractionated postprostatectomy radiotherapy(COPORT) in treating patients with localized…
- Trial name
- NCT06325995
- Testing
- Conventional radiation therapy, Hypofractionated radiation therapy
- Where
- China
- Volunteers
- 428 people
- Sponsor
- Changhai Hospital
Cancer Survivor, Depression
Helping African American Prostate Cancer Survivors and Their Partners Cope With Challenges After Surgery for Prostate Cancer
RATIONALE: Telephone counseling after radical prostatectomy may help African American prostate cancer survivors and their intimate partners cope with the problems and challenges of surgery, and may reduce distress and improve…
- Conditions
- Cancer Survivor, Depression, Gastrointestinal Complications, Male Erectile Disorder
- Trial name
- NCT00869739
- Testing
- telephone-based intervention, educational intervention, partner-assisted coping skills training
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Prostate Cancer
High-Intensity Focused Ultrasound Ablation in Treating Patients With Progressive Prostate Cancer
RATIONALE: High-intensity focused ultrasound ablation uses high-energy sound waves to kill tumor cells. PURPOSE: This phase II trial is studying the side effects of high-intensity focused ultrasound ablation and to see how well…
- Trial name
- NCT00987675
- Testing
- pharmacological study, questionnaire administration, assessment of therapy complications
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- University College London Hospitals
Patients Scheduled for Prostate Biopsy Because of Increased Serum PSA and/or Abnormal Digital Rectal Examination
Medical Economics of Urinary PCA3 Test for Prostate Cancer Diagnosis
The ultrasound-guided biopsies of the prostate is the validated technique for the diagnosis of prostate cancer, the first human cancer and second leading cause of cancer death.
- Trial name
- NCT01632930
- Testing
- urinary PCA3 test using Progensa® PCA3 assay kit (Gen-Probe)
- Where
- 10 sites in France
- Volunteers
- 962 people
- Sponsor
- Hospices Civils de Lyon
Prostate Cancer
Prostate Cancer IMAGing IN Early Detection (IMAGINED Trial)
The researchers hope to learn if specific types of MRI software and techniques can help improve early prostate cancer detection at time of a MRI-guided prostate biopsy.
- Trial name
- IMAGINED (NCT05882253)
- Testing
- Restricted Spectrum Imaging-Magnetic Resonance Imaging (RSI-MRI)
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- University of California, San Diego
Prostate Cancer
Early Stage Prostate Cancer Cohort
Environmental factors such as diet and cigarette smoking may play a role in predicting the progression of early stage prostate cancer to advance disease.
- Trial name
- NCT00011349
- Where
- 13 sites in United States
- Volunteers
- 1,116 people
- Sponsor
- US Department of Veterans Affairs
Prostate Cancer
Gene-Environment Interaction in Prostate Cancer
The purpose of this study is to determine whether certain environmental factors, namely occupational exposures and diet, have a greater effect on prostate cancer risk in the presence of selected inherited genetic factors.
- Trial name
- NCT00041847
- Where
- United States
- Volunteers
- 881 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Prostate Cancer
Comparison of Duration of Treatment Interruption With or Without Curcumin During the Off Treatment Periods in Patients With Prostate Cancer Undergoing Intermittent Androgen Deprivation Therapy
This was a placebo-controlled, double-blind, randomized trial designed with the aim of establishing whether curcumin influenced the duration of treatment interruption and rate of prostatic specific antigen(PSA) progression…
- Trial name
- NCT03211104
- Testing
- curcumin
- Volunteers
- 107 people
- Sponsor
- Samsung Medical Center
Prostate Cancer, Cardiovascular Death
Influence of Hormone Therapy on Heart Attack Incidence in Men Undergoing Prostate Brachytherapy
The purpose of this study is to review cause of death in patients undergoing prostate brachytherapy at a single institution. Furthermore, we are analyzing patients undergoing androgen deprivation therapy and whether or not this…
- Trial name
- NCT00651222
- Testing
- No intervention was required
- Where
- United States
- Sponsor
- Prostate Cancer Foundation of Chicago
Prostatectomy
A Comparison of Radical Prostatectomy and Precision Prostatectomy in Low- and Intermediate-risk Prostate Cancers.
Prostate cancer (PCa) management for low- and intermediate-risk patients often involves radical prostatectomy (RP), which achieves oncologic control but is associated with significant functional impairments, such as erectile…
- Trial name
- NCT07348367
- Testing
- Radical Prostatectomy, Precision Prostatectomy
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Henry Ford Health System
Adenocarcinoma of the Prostate
Pilot Study of DRibble Vaccine for Prostate Cancer Patients
This is a pilot study of the DRibble vaccine in patients with advanced prostate cancer.
- Trial name
- DRibble (NCT02234921)
- Testing
- Cyclophosphamide, DRibble Vaccine, HPV Vaccinations
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- UbiVac
Prostate Cancer
Shared Decision Making: Prostate Cancer Screening
Interventions to Improve Shared Decision-Making: Prostate Cancer Screening is a prospective study of educational interventions to improve the interaction of physicians and their patients about prostate cancer screening.
- Trial name
- NCT00207649
- Testing
- Shared decision-making for PSA screening tool
- Where
- United States
- Volunteers
- 641 people, healthy volunteers welcome
- Sponsor
- Lisa Richarson
Prostate Cancer
Dolastatin 10 in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Previous Hormone Therapy
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of dolastatin 10 in treating patients with metastatic…
- Trial name
- NCT00003626
- Testing
- dolastatin 10
- Where
- 3 sites in United States
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Prostate Cancer, Quality of Life
Clinical and Quality of Life Outcomes After Open or Robotic-Assisted Laparoscopic Radical Prostatectomy
The goal of the study is to look at surgical recovery and quality of life for men who have an open versus robotic-assisted laparoscopic radical prostatectomy (RP). RP is a procedure that removes the prostate gland.
- Trial name
- NCT00578123
- Testing
- Quality of Life Questionnaires
- Where
- United States
- Volunteers
- 959 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Prostatic Neoplasms, Prostatectomy
Impact of Tamsulosin on Voiding Patterns Following Early Catheter Removal After Robot-assisted Laparoscopic Radical Prostatectomy
To date, there is a lack of consensus concerning the optimal timing for removal of the urethral catheter, its related complications, the effectiveness in prophylactic drug use to reduce complication, and the patient reported…
- Trial name
- NCT01209988
- Testing
- tamsulosin 0.4mg, No medication
- Where
- South Korea
- Volunteers
- 220 people
- Sponsor
- Asan Medical Center
Prostate Cancer
Quality of Life Analysis of Treatment in Patients With Prostate Cancer on Adjuvant Zoladex Therapy
This is an open label, non-interventional quality of life analysis for Zoladex treated prostate cancer patients by investigator's questionnaire
- Trial name
- AZTEK EXT (NCT00692874)
- Where
- 20 sites in Hungary
- Volunteers
- 1,646 people
- Sponsor
- AstraZeneca
Prostate Cancer
Biological Therapy in Treating Patients With Prostate Cancer
RATIONALE: Biological therapies use different ways to stimulate the immune system and stop tumor cells from growing. Treating a person's T cells in the laboratory and then reinfusing them may cause a stronger immune response and…
- Trial name
- NCT00039299
- Testing
- therapeutic autologous lymphocytes
- Where
- United States
- Sponsor
- Jonsson Comprehensive Cancer Center
Prostate Cancer
Pain Comparison: Transrectal vs. Transperineal Prostate Biopsy
Prostate biopsy remains the gold standard for the diagnosis of prostate cancer and is most commonly performed using either the transrectal or transperineal approach.
- Trial name
- TRAP-PAIN (NCT07577895)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Kayseri Education and Research Hospital