Clinical trials: Prostatic Biopsy
Prostate Cancer (Diagnosis)
Virtual Biopsy of Prostate Cancer Using PSMA PET and AI
Prostate cancer is the most common type of cancer in Norwegian men, but many tumors are slow-growing and do not require treatment.
- Trial name
- NCT07266129
- Where
- Norway
- Volunteers
- 220 people
- Sponsor
- University Hospital of North Norway
Prostate Cancer, PSA
Prostate Biopsy, Transrectal vs. Transperineal: Efficacy and Complications
This study evaluates the difference between 2 prostate biopsy methods, transrectal (through the rectal wall) and transperineal (through the skin) needle biopsy.
- Conditions
- Prostate Cancer, PSA, Infection
- Trial name
- ProBE-PC (NCT04081636)
- Testing
- Systematic Transrectal biopsy (TR-Bx), Targeted Transrectal biopsy (TR-Bx), Systematic Transperineal biopsy (TP-Bx)
- Where
- United States
- Volunteers
- 840 people
- Sponsor
- Albany Medical College
Diagnoses Disease
Micro-Ultrasound/Magnetic Resonance Imaging 001
Micro-ultrasound is a novel real-time imaging modality which maintains the clinical workflow of conventional ultrasound-guided prostate biopsy, while potentially maintaining a similar ability to detect clinically significant…
- Trial name
- NCT03938376
- Testing
- Micro-Ultrasound guided biopsy
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
Patients With Suspected Prostate Cancer
Multicentric Comparative Prospective Study of the Benefits and Risks of Biopsy Prostate Using Transrectal or Transperineal Procedure for the Prostate Cancer Diagnostic
The performance of prostatic biopsies is an essential element to confirm the diagnosis of prostate cancer and to specify the characteristics of the tumor in terms of stage and grade.
- Trial name
- BIOPROSTABORD (NCT05763355)
- Testing
- Biopsy
- Where
- 2 sites in France
- Volunteers
- 101 people
- Sponsor
- Elsan
Infectious Complications Following Prostate Biopsy, Prostate Cancer
A Study Comparing Infectious Complications After Transperineal Prostate Biopsy With or Without Antibiotic Prophylaxis
Prostate biopsy performed through the perineal skin (the area between the testicles and the anus), known as a transperineal biopsy, is currently considered the standard procedure for diagnosing prostate tumors, having replaced…
- Trial name
- NCT07557901
- Testing
- No antibiotic prophylaxis for prostate biopsy, Antibiotic prophylaxis (fosfomycin-trometamol) for prostate biopsy.
- Where
- Slovakia
- Volunteers
- 300 people
- Sponsor
- F.D. Roosevelt Teaching Hospital with Policlinic Banska Bystrica
Prostate Cancer, Genetic Predisposition
In Situ Clonal Heterogeneity in Prostatic Diagnostic Biopsies
This is a retrospective, proof of concept study, which aims at reconstructing the cellular heterogeneity of the tumor in multi-needle diagnostic prostate biopsy as well as any biopsy containing potentially pre-malignant tissue…
- Trial name
- NCT04873427
- Testing
- clonal heterogeneity evaluation
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Clinica Luganese Moncucco
Prostatic Neoplasms
Prostate Hyperfixation on PET-choline in Patients With Prostate Cancer: Correlation With MRI and Pathological Data (LOC-CHOLINE)
In France, when prostate cancer is suspected, multiparametric MRI is the reference imaging technique for tumor localization, and is used to guide biopsies in order to characterize the tumor as accurately as possible.
- Trial name
- LOC-CHOLINE (NCT06836154)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Brest
Prostate Cancer
PSMA PET/CT vs. mpMRI in Patients With a High Suspicion of Prostate Cancer: a Head to Head, Parallel, Prospective Trial
This is prospective single-arm case-control study designed to compare in parallel PSMA PET/TRUS (trans-rectal or trans-perineal) fusion biopsy ("experimental test") with mpMRI/TRUS fusion prostate biopsy ("standard test") in men…
- Trial name
- PROSPET-BX (NCT05297162)
- Testing
- PSMA PET/TRUS (trans-rectal or trans-perineal) fusion biopsy
- Where
- Italy
- Volunteers
- 128 people
- Sponsor
- Istituto Clinico Humanitas
Prostate Cancer
Randomized Controlled Trial of MRI Target Biopsy: Transrectal vs. Transperineal
This prospective study of comparing between Transrectal and transperineal prostate MRI targeted biopsy to provide evidence for clinicians to select the appropriate biopsy approach under different conditions.
- Trial name
- NCT03650153
- Testing
- Trans-rectal MRI targeted Biopsy, Trans-perineal MRI targeted Biopsy
- Where
- Saudi Arabia
- Volunteers
- 165 people
- Sponsor
- Princess Al-Johara Al-Ibrahim Cancer Research Center
Prostate Infection
Antibiotic Prophylaxis for Transrectal Prostate Biopsy-Ciprofloxacin vs. Trimethoprim/Sulfamethoxazole
This study will examine if a single dose of Ciprofloxacin and Trimethoprim/Sulfamethoxazole are equivalent for prophylaxis immediately prior to prostate biopsy, when a patient has a suspected prostate cancer.
- Trial name
- NCT02734732
- Testing
- Trimethoprim/Sulfamethoxazole, Ciprofloxacin
- Where
- 5 sites in Sweden
- Volunteers
- 2,800 people
- Sponsor
- Umeå University
Prostate Cancer
Magnetic Resonance Imaging-Transrectal Ultrasound Fusion Image-Guided Prostate Biopsy Following Radical Prostatectomy in Patients With Prostate Cancer
This pilot clinical trial studies magnetic resonance imaging (MRI)-transrectal ultrasound (TRUS) fusion image-guided prostate biopsy following radical prostatectomy in patients with prostate cancer.
- Trial name
- NCT01764347
- Testing
- therapeutic conventional surgery, ultrasound-guided prostate biopsy, magnetic resonance imaging
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Southern California
Prostatic Neoplasms, Diagnostic Techniques and Procedures
SmartTarget: BIOPSY
The purpose of this study is to determine how well SmartTarget guided prostate biopsies perform, compared with our current standard of "visually directed biopsies" in the detection of prostate cancer.
- Trial name
- NCT02341677
- Testing
- SmartTarget - Biopsy
- Where
- United Kingdom
- Volunteers
- 134 people
- Sponsor
- University College, London
Prostate Cancer
Biopsy Study Comparing MRI and Ultrasound Soft Image Fusion Guided Biopsies and Gold Standard Prostate Biopsies.
Background: Prostate biopsies are usually performed due to accidentally discovered elevated prostate specific antigen (PSA) and/or abnormal digital rectal examination.
- Trial name
- NCT01455792
- Testing
- Biopsies using image fusion, Gold standard biopsy
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Prostate Cancer
Virtual Prostate Biopsy Protocol for Patients on Active Surveillance and at Risk of Prostate Cancer
The purpose of this study is to examine the use of MRI surveillance for patients with no prostate cancer, potential prostate cancer, or diagnosed low-grade prostate cancer.
- Trial name
- NCT03823001
- Testing
- virtual biopsy (VB) monitoring protocol
- Where
- United States
- Sponsor
- Case Comprehensive Cancer Center
Prostate Cancer
Clinical Study Evaluating Targeted Biopsies and Cytological Imprints in Prostate Cancer
The investigators will evaluate the accuracy of performing cytological imprints of targeted biopsies when diagnosing prostate cancer.
- Trial name
- NCT01745718
- Testing
- Cytological imprints
- Where
- Norway
- Sponsor
- Oslo University Hospital
Prostate Cancer
A Prospective Randomized Trial of Prostate Biopsy Protocols Comparing the Vienna Nomogram and a Standard 10-core Biopsy Scheme
In this study, the investigators aim to determine if the Vienna nomogram increases the detection rate of TRUS-guided prostate biopsies by conducting a prospective randomized study comparing the Vienna nomogram with a 10-core…
- Trial name
- NCT01752140
- Testing
- 10-core prostate biopsy protocol, Vienna nomogram prostate biopsy protocol
- Where
- Portugal
- Volunteers
- 463 people
- Sponsor
- Hospital de Santa Maria, Portugal
Prostate Neoplasms, Prostate Biopsy
Effects of Music and Conversation in Prostate Biopsy
The goal of this observational study is to learn about the effects of music and conversation on pain and anxiety levels during Transrectal Ultrasound-Guided Prostate Biopsy.
- Trial name
- TRUS-BX (NCT07006779)
- Testing
- Music intervention, Conversation
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bozok University
Prostate Cancer
Comparison of a Novel Transperineal Targeted Fusion Biopsy System to Conventional Transrectal Targeted Fusion Biopsy
This study is designed as a randomized control trial which intends to determine if transperineal (TP) targeted biopsy is not inferior to transrectal (TR) targeted biopsy for diagnosis of clinically significant prostate cancer…
- Trial name
- NCT03936127
- Testing
- Ultrasound (US) Targeted Fusion Biopsy
- Where
- Canada
- Volunteers
- 360 people
- Sponsor
- Dr. Nicola Schieda
Prostate Cancer
Early Staged Consent Before Prostate Biopsy
This is a study and a novel approach to clinical trials, testing the feasibility and acceptability of two-stage consent in the context of a trial integrated into routine clinical practice.
- Trial name
- NCT03507725
- Testing
- Meditation, Prostate Biopsy, Questionnaires
- Where
- United States
- Volunteers
- 390 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Prostate Cancer
Pathological Positivity Rate in Prostate Cancer Patients with PI-RADS 4 and First Negative Biopsy
The purpose of this prospective, single-center, single-arm trial was to evaluate the pathologic type of re-treatment based on a clear PI-RADS score of ≥4 with a first negative prostate biopsy, belonging to the high-risk group of…
- Trial name
- NCT06677775
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Anhui Provincial Hospital