Clinical trials: Prostatic Biopsy
Prostate Cancer
Ketoconazole, Hydrocortisone, Dutasteride and Lapatinib (KHAD-L) in Prostate Cancer
The purpose of this research study is to determine the safety of giving ketoconazole, hydrocortisone and dutasteride (KHAD) with lapatinib.
- Trial name
- KHLAD (NCT00953576)
- Testing
- ketoconazole, hydrocortisone, dutasteride
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- Dana-Farber Cancer Institute
Prostate Cancer, Benign Prostatic Hyperplasia
3D Recording of a Trans-rectal Prostate Biopsy
Prostate biopsy is performed by multiple consecutive biopsy needle insertion into the prostate gland under a trans-rectal ultrasound probe guidance.
- Trial name
- NCT01314456
- Testing
- NaviGo
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- HaEmek Medical Center, Israel
Prostate Cancer
Radioactive Counts From PSMA PET/CT-Targeted Biopsy Specimens for Real-time Diagnosis of Prostate Cancer: A Prospective Study
This study aims to establish the diagnostic threshold and efficacy of radioactive counts (CPM) from biopsy specimens in distinguishing cancer-containing from non-cancer-containing cores, using prostate biopsy pathology as the…
- Trial name
- NCT07709403
- Testing
- No intervention (observational study)
- Volunteers
- 20 people
- Sponsor
- Peking University First Hospital
Prostate Cancer
Prostate Cancer Upgrading Reference Set
Research repository designed to establish prostate cancer upgrading reference set and development of a risk prediction tool. Repository will include clinical information and biologics on a cohort of 240 men, to predict presence…
- Trial name
- NCT02189486
- Where
- United States
- Volunteers
- 382 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Prostate Cancer (Diagnosis)
Virtual Biopsy of Prostate Cancer Using PSMA PET and AI
Prostate cancer is the most common type of cancer in Norwegian men, but many tumors are slow-growing and do not require treatment.
- Trial name
- NCT07266129
- Where
- Norway
- Volunteers
- 220 people
- Sponsor
- University Hospital of North Norway
Prostate Cancer, Clinically Significant Prostate Cancer
Transperineal Versus Transrectal Cognitive Fusion Prostate Biopsy
This prospective randomized controlled trial aims to compare transperineal and transrectal cognitive fusion prostate biopsy techniques in patients with suspicious prostate lesions detected by multiparametric magnetic resonance…
- Conditions
- Prostate Cancer, Clinically Significant Prostate Cancer, Cognitive Fusion
- Trial name
- PROCOG (NCT07710807)
- Testing
- Transrectal Cognitive Fusion Prostate Biopsy, Transperineal Cognitive Fusion Prostate Biopsy
- Where
- Turkey (Türkiye)
- Volunteers
- 280 people
- Sponsor
- Ankara Etlik City Hospital
Prostate Cancer, Prostate Adenocarcinoma
MRI-Based Active Surveillance to Avoid the Risks of Serial Biopsies in Men With Low-Risk Prostate Ca
Phase II non-inferiority randomized trial of annual systematic biopsies versus mpMRI and targeted biopsies for men with low risk prostate cancer on active surveillance with any volume Gleason's Score 6, but no prior MRI imaging…
- Conditions
- Prostate Cancer, Prostate Adenocarcinoma, Multiparametric MRI, Gleason's Score 6
- Trial name
- NCT02564549
- Testing
- TRUS-guided biopsy, mpMRI with targeted biopsy
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Virginia Commonwealth University
Prostate Cancer
Improving Prostate Cancer Detection Using MRI-Targeted TRUS-Guided Biopsy
The purpose of this study is to determine if using MRI can improve cancer detection by identifying potential cancer targets prior to TRUS-guided biopsy in populations that have previous inconclusive results from TRUS-guided…
- Trial name
- NCT02488096
- Testing
- TRUS-Guided Biopsy, MRI + TRUS-Guided Biopsy
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Saskatchewan Health Authority - Regina Area
Elevated PSA, Prostate Cancer
Functional and Morphologic MRI in the Detection of Prostate Cancer in Patients With Prior Negative Biopsy
Prostate specific antigen (PSA) and digital rectal exam (DRE) are used to screen for prostate cancer. Patients with abnormal DRE or elevated PSA undergo transrectal ultrasound guided biopsy (TRUS-Bx).
- Trial name
- NCT00242060
- Testing
- MRI
- Where
- Canada
- Sponsor
- University Health Network, Toronto
Prostate Cancer
68Ga-PSMA PET/MRI in Conjunction With mpMRI for Evaluating Prospective Prostate Cancer Risk
The goal of this observational study is to learn if Ga-68 PSMA PET/MRI can better diagnose prostate cancer than mpMRI in males between 40 to 85 years old who is naive to prostate biopsy and is suspicious for prostate cancer by…
- Trial name
- NCT06494696
- Testing
- Ga-68 PSMA PET/MRI
- Where
- Taiwan
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Prostate Cancer
Prospective Evaluation of Proclarix® Test to Improve Risk Stratification in Men Scheduled for MpMRI and Prostate Biopsy in Cantonal Hospital Aarau
The use of prostate-specific antigen (PSA) for the screening of prostate cancer has led to higher detection rates and a shift to lower and therefore potentially more curative disease stages at diagnosis and thus subsequently to a…
- Trial name
- NCT06637267
- Testing
- Proclarix®
- Where
- Switzerland
- Volunteers
- 480 people
- Sponsor
- Kantonsspital Aarau
Prostate Cancer
A Study of Vismodegib in Men With Metastatic CRPC With Accessible Metastatic Lesions for Tumor Biopsy
This is a single-arm pharmacodynamic study with mandatory metastatic tumor biopsies in men with castration-resistant prostate cancer.
- Trial name
- NCT02115828
- Testing
- Vismodegib
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Prostate Neoplasm
Targeted Biopsy or Standard Biopsy for Clinical Significant Prostate Cancer Detection
This randomized controlled trial aims to assess the detection rate of clinically significant and clinically insignificant cancer of mpMRI-targeted biopsy compared to transperineal standard biopsy in men with clinical suspicion of…
- Trial name
- NCT03572946
- Testing
- Targeted prostate biopsy, Standard biopsy
- Where
- China
- Volunteers
- 400 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Cancer of Prostate
Pain Comparison Whit Visual Analog Scale (EVA) Between Four Analgesic Methods During Trans Rectal Prostatic Biopsy
Define the best analgesic method between peri prostatic blockage, analgesic suppository, oral analgesic and topic anesthetic gel, during trans rectal prostate biopsy
- Trial name
- NCT03442075
- Where
- Mexico
- Volunteers
- 70 people
- Sponsor
- Instituto Mexicano del Seguro Social
Cancer of Prostate
Dynamic Focusing Evaluation for Prostate Cancer Treatment
Define the best acoustic parameters for the dynamic focusing HIFU transducer in the treatment of localized Prostate Cancer.
- Trial name
- FOC/DYN (NCT03632980)
- Testing
- "Ablatherm Foc/Dyn" or "Focal One" HIFU treatment
- Where
- France
- Volunteers
- 180 people
- Sponsor
- EDAP TMS S.A.
Urinary Tract Infections
Efficacy Study of Prophylaxis With Fosfomycin Versus Ciprofloxacin Prior Prostate Biopsy
The purpose of this clinical trial is compare the incidence of symptomatic or asymptomatic bacteriuria after transrectal ultrasound guided prostate biopsy using a single dose of fosfomycin 3 g one hour before the biopsy compared…
- Trial name
- BIPROST (NCT01803191)
- Testing
- Fosfomycin 3 g, Ciprofloxacin 500 mg
- Where
- 3 sites in Spain
- Volunteers
- 461 people
- Sponsor
- Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
Prostate Cancer, Pathology
Decade-Long Insights Into Transperineal Prostate Biopsy in a West China Population
Prostate cancer (PCa) remains one of the most prevalent malignancies affecting men globally. The disease spectrum of PCa ranges from indolent tumors, which may require minimal to no intervention, to aggressive, potentially lethal…
- Trial name
- NCT06366308
- Testing
- Transperineal Prostate Biopsy
- Volunteers
- 10,000 people
- Sponsor
- West China Hospital
Prostate Cancer
Focal Therapy Using HIFU for Localised Prostate Cancer
To evaluate the rate of patients without cancer detected by biopsies performed six months after hemi-ablation with high intensity focused ultrasound (HIFU) (Ablatherm ®).
- Trial name
- NCT02016040
- Testing
- High Intensity Focused Ultrasound
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Jewish General Hospital
Prostate Cancer
Optimizing Prostate Cancer Treatment in Men With Advanced Local Disease
Multi-modality therapy that includes a brachytherapy implant improves outcomes in locally advanced prostate cancer when compared to other radiation-based treatments, but is also associated with more adverse side effects.
- Trial name
- OPTiMAL (NCT03836196)
- Testing
- LDR Brachytherapy and External Beam Radiation Therapy
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- British Columbia Cancer Agency
Prostate Cancer, PSA
Prostate Biopsy, Transrectal vs. Transperineal: Efficacy and Complications
This study evaluates the difference between 2 prostate biopsy methods, transrectal (through the rectal wall) and transperineal (through the skin) needle biopsy.
- Conditions
- Prostate Cancer, PSA, Infection
- Trial name
- ProBE-PC (NCT04081636)
- Testing
- Systematic Transrectal biopsy (TR-Bx), Targeted Transrectal biopsy (TR-Bx), Systematic Transperineal biopsy (TP-Bx)
- Where
- United States
- Volunteers
- 840 people
- Sponsor
- Albany Medical College