Clinical trials: Psychologic Adaptation
Pediatric Solid Tumor
UGT1A1 Genotype-drien Phase I Study of Irinotecan in VIT Regimen for the Treatment of Pediatric R/R Solid Tumors
Irinotecan is a commonly used salvage chemotherapy drug for children with relapsed and refractory solid tumors. Common dose-limiting toxicities of irinotecan include abdominal pain and diarrhea.
- Trial name
- NCT06760117
- Testing
- Irinotecan (CPT-11), Temozolomide (TMZ), Vincristine
- Where
- China
- Volunteers
- 39 people
- Sponsor
- Sun Yat-sen University
Anxiety Disorder/Anxiety State, Depressive Disorder/Psychology
Adapting Mental Health Interventions for War-Affected Youth Through Employment Programs
The research will first examine data obtained from YRI participants to investigate effects of the group sessions on psychosocial functioning outcomes in youth aged 15 - 24.
- Conditions
- Anxiety Disorder/Anxiety State, Depressive Disorder/Psychology, Social Problems/Psychology, Violence, Non-accidental
- Trial name
- NCT02561949
- Testing
- YRI, Income generating activity program
- Where
- Sierra Leone
- Volunteers
- 80 people
- Sponsor
- Boston College
Prodromal Schizophrenia, Prodromal Psychosis
Aripiprazole Treatment of the Prodrome
The RAP Program is conducting a research study of the antipsychotic medication Aripiprazole. This drug has been approved for treating symptoms associated with schizophrenia and is associated with fewer side effects.
- Trial name
- NCT00169949
- Testing
- aripiprazole
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Northwell Health
Inflammatory Bowel Diseases, Depressive Episode
Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health
This study is a large population-based analysis in the United Kingdom (UK) using routine primary care data to investigate the impacts on quality-of-life outcomes and use of healthcare services in people aged 5 - 25 years…
- Conditions
- Inflammatory Bowel Diseases, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorder
- Trial name
- NCT05206734
- Testing
- No specific intervention
- Where
- United Kingdom
- Volunteers
- 19,469 people, healthy volunteers welcome
- Sponsor
- Momentum Data
Myopia
Study of Viziatek ISL™ Refractive Phakic Intra Sulcus Lens for Refraction Adjustment in Blind Volunteers
This is a clinical investigation. A total of up to 5 subjects, but not less than 3 at one investigational site will undergo insertion of the ISL in one eye and will be followed through 6 months postoperative.
- Trial name
- NCT05518344
- Testing
- Viziatek ISL™ (hereinafter referred to as the "ISL") implanted in blind eye.
- Where
- Latvia
- Volunteers
- 4 people
- Sponsor
- Hanita Lenses
Depression
Group Interpersonal Psychotherapy for Depressed Adolescents in School-based Clinics
This study will assess the effectiveness of group interpersonal psychotherapy (IPT-AG) versus treatment as usual (TAU) in improving the treatment of depressed adolescents in school-based health clinics.
- Trial name
- NCT00270244
- Testing
- Group interpersonal psychotherapy for depressed adolescents (IPT-AG), Treatment as usual (TAU)
- Volunteers
- 16 people
- Sponsor
- New York State Psychiatric Institute
Lupus
Improving Quality of Life for African American Female Adolescents With Lupus
This study will evaluate a program designed to help African American adolescents with lupus (systemic lupus erythematosus or SLE) cope with the disease.
- Trial name
- NCT00068874
- Testing
- Coping skills and cognitive restructuring techniques, Educational training
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Medical University of South Carolina
Advanced Malignant Neoplasm
Enhancing Connections Program in Improving Family Adjustment in Patients With Incurable Cancer
This pilot clinical trial studies how well the Enhancing Connections program improves family adjustment in patients with incurable cancer.
- Trial name
- NCT03049397
- Testing
- Communication Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Psychological Distress, Suicidal Ideation
Flourish in Schools Pilot Study
This study will test Flourish, a digital suicide prevention intervention for cyberbullied youth, within schools. Specifically, the study aims to: 1.
- Trial name
- NCT07506525
- Testing
- Flourish
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Candice Biernesser
Chronic Motor or Vocal Tic Disorder, Tourette's Disorder
Aripiprazole in Children and Adolescents With Chronic Tic Disorder or Tourette's Disorder
The purpose of this trial is to demonstrate the efficacy and safety of aripiprazole in children and adolescents aged 6~18 years with chronic tic disorders or Tourette's disorder
- Trial name
- NCT00706589
- Testing
- aripiprazole
- Where
- 6 sites in South Korea
- Volunteers
- 61 people
- Sponsor
- Korea Otsuka Pharmaceutical Co., Ltd.
Congestive Heart Failure (CHF)
Group Psychotherapy Among Congestive Heart Failure Patients
This study will examine the efficacy of group therapy utilizing the Existential Approach in heart failure patients when compared to a control group of patients who are waiting for the same group treatment.
- Trial name
- NCT01414439
- Testing
- Existential Group Therapy
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Meir Medical Center
Mental Disorders
Regulating Emotions Through Adapted Dialectical Behavior Skills for Youth (READY-Nepal)
Published research on the development of mental health symptomatology among adolescents has expanded in recent years and indicates the presence of a growing public health concern.
- Trial name
- READY-Nepal (NCT03807427)
- Testing
- READY-Nepal
- Where
- Nepal
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Brandon A Kohrt, MD, PhD
Hemolytic-Uremic Syndrome, Children
Haemolytic Uraemic Syndrome in Childhood: Clinical, Cognitive and Psychological Aspects
The purpose of this study is to investigate the clinical, cognitive outcome and psychosocial outcome of haemolytic uraemic syndrome in childhood.
- Conditions
- Hemolytic-Uremic Syndrome, Children, Parents, Psychological Adjustment
- Trial name
- NCT01666548
- Where
- Switzerland
- Volunteers
- 89 people
- Sponsor
- University Children's Hospital, Zurich
Pediatric Cancers
School Reintegration Outcomes in Pediatric Cancer Patients
Primary Objectives: 1. To examine illness-related factors (i.e., severity of illness, quality of life rating) as predictors or correlates of child adjustment to pediatric cancer. 2.
- Trial name
- NCT00477256
- Testing
- Questionnaires
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Major Depressive Disorder, Dysthymic Disorder
The Efficacy of Parent Involvement in the Treatment of Adolescent Depression
The primary aim of this study is to examine whether adolescent depression and the family context in which it develops is best treated using an individual adolescent intervention or an intervention that includes both the…
- Conditions
- Major Depressive Disorder, Dysthymic Disorder, Depressive Disorder NOS, Adjustment Disorder
- Trial name
- NCT00883519
- Testing
- Interpersonal Psychotherapy for Depressed Adolescents, Interpersonal Psychotherapy for Depressed Adolescents and Parents
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- New York State Psychiatric Institute
Type One Diabetes Mellitus
Evaluation of a Mobile Application Designed to Support Type 1 Diabetic Patients in Adjusting Their Insulin Doses.
Title: Evaluating a Mobile Application for Insulin Management in Iraqi Type 1 Diabetes Patients. The goal of this clinical trial is to determine whether a mobile health application can improve insulin management and blood sugar…
- Trial name
- NCT07234500
- Testing
- mHealth Mobile Application, Standard Care (in control arm)
- Where
- Iraq
- Volunteers
- 50 people
- Sponsor
- University of Baghdad
Breast Cancer
Impact of a Rehabilitation Programme for Mothers With Breast Cancer and Their Children
About 1/3 of newly diagnosed breast cancer patients are mothers of children who still live at home. They face additional challenges and stress, their children are also affected by the mother's illness.
- Trial name
- NCT00916825
- Testing
- rehabilitation programme "getting better together"
- Where
- Germany
- Volunteers
- 801 people
- Sponsor
- Philipps University Marburg
To Examine the Effects of Mobile App Support Provided to Expectant Fathers, Based on Transition Theory, on Anxiety, Bonding With the Fetus, and Marital Harmony
MOBİLE APP SUPPORT BASED ON TRANSİTİON THEORY FOR EXPECTANT FATHERS
THİS STUDY; İS DESİGNED TO EXAMİNE THE EFFECTS OF A MOBİLE APPLİCATİON-DEVELOPED BASED ON TRANSİTİON THEORY-PROVİDED TO EXPECTANT FATHERS ON ANXİETY, FETAL BONDİNG, AND MARİTAL ADJUSTMENT.
- Trial name
- NCT07767045
- Testing
- Mobile app support
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Ege University
Type 1 Diabetes
Use of Insulin Adjustment Device DreaMed Endo Digital During Routine Clinical Use for Subjects With Diabetes Type 1
The DreaMed Endo.Digital is indicated for use by healthcare professionals treating individuals with Type 1 Diabetes (T1D) who use insulin pump or multiple daily injections (MDI) as their insulin delivery therapy and monitor their…
- Trial name
- Endo digital (NCT05610722)
- Testing
- DreaMed Endo Digital
- Where
- Israel
- Volunteers
- 1 people
- Sponsor
- Rabin Medical Center
Cerebral Palsy, Traumatic Brain Injuries
Effects of an Adapted Ski/Snowboarding Program on Quality of Life in Children With Physical Disabilities
This study is assessing quality of life in children with a physical disability who participate in the Children's Hospital Colorado Hospital Sports Program (HSP), where children with physical disabilities are able to participate…
- Conditions
- Cerebral Palsy, Traumatic Brain Injuries, Spinal Cord Injuries, Physical Disability
- Trial name
- NCT02110290
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of Colorado, Denver