Clinical trials: Psychology
Evidence of Liver Transplantation, Rejection
Safety and Efficacy of Alemtuzumab in Pediatric Intestinal Transplantation
This open-label clinical trial will evaluate the safety and efficacy of Alemtuzumab (Campath, Bayer Corp., Pittsburgh) in children (0-17) and adults (18-25) receiving intestinal transplant.
- Conditions
- Evidence of Liver Transplantation, Rejection, ALEMTUZUMAB
- Trial name
- NCT01208337
- Testing
- Alemtuzumab
- Volunteers
- 23 people
- Sponsor
- University of Pittsburgh
Emotions
Effect of Emotion Mindsets on Emotion Processing
The guiding scientific premise for this research is that a growth emotion mindset will promote more adaptive emotion processing than a fixed emotion mindset.
- Trial name
- NCT03978871
- Testing
- Growth Mindset, Brain Education
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- University of Illinois at Urbana-Champaign
Type 1 Diabetes Mellitus
Check It! Positive Psychology Intervention to Improve Adherence in Adolescents With T1D
Problems with diabetes management in adolescents with type 1 diabetes are common - occurring at rates as high as 93% - and have serious health consequences, including poor blood sugar control and risk for later complications.
- Trial name
- NCT02746627
- Testing
- Positive Affect, Education
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Vanderbilt University Medical Center
Kidney Failure, Chronic, End-Stage Renal Disease
Clazakizumab in Highly-HLA Sensitized Patients Awaiting Renal Transplant
Patients who have had a previous allograft failure represent a major problem for transplant centers as they are highly-human leukocyte antigen (HLA) sensitized and unlikely to receive another transplant without significant…
- Conditions
- Kidney Failure, Chronic, End-Stage Renal Disease, Transplant Glomerulopathy, Transplant;Failure,Kidney
- Trial name
- NCT03380962
- Testing
- Clazakizumab
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Stanley Jordan, MD
Pediatric Heart Transplantation, Immunosuppression
Tacrolimus/Everolimus vs. Tacrolimus/MMF in Pediatric Heart Transplant Recipients Using the MATE Score
The TEAMMATE Trial will enroll 210 pediatric heart transplant patients from 25 centers at 6 months post-transplant and follow each patient for 2.5 years.
- Conditions
- Pediatric Heart Transplantation, Immunosuppression, Chronic Kidney Diseases, Cardiac Allograft Vasculopathy
- Trial name
- TEAMMATE (NCT03386539)
- Testing
- Everolimus, Tacrolimus, Mycophenolate Mofetil
- Where
- 25 sites in United States
- Volunteers
- 211 people
- Sponsor
- Boston Children's Hospital
Renal Transplant Rejection
Imaging Kidney Transplant Rejection Using Ferumoxytol-Enhanced Magnetic Resonance
The goal of this study is to develop a non-invasive imaging test for in vivo detection of kidney transplant rejection. The hypotheses are that 1) Ferumoxytol-MRI can generate accurate estimates of tissue iron concentrations and…
- Trial name
- NCT02006108
- Testing
- Feraheme, MRI-GE Healthcare 3 Tesla magnet
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Stanford University
Mental Well-being, Happiness
Joyful Parenting Pilot Project RCT Study
Aims: To enhance mental well-being of adolescents, adults and their families by creating a positive, happy and joyful environment in the community. Targets: Parents aged 12-59 and their family members in Hong Kong.
- Trial name
- NCT03282071
- Testing
- Joyful Parenting Intervention
- Where
- 2 sites in Hong Kong
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Psychology, Social, Adolescent Behavior
Exposure to Gun Violence in Video Games Increases Interest in Real Guns
More American children die by accidental gun use than children in other developed countries. One factor that can influence children's interest in guns is exposure to media containing guns.
- Trial name
- NCT03259139
- Testing
- Video games and violence
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Psychology, Social, Adolescent Behavior
Viewing Movie Violence & Interest in Guns
More American children die by accidental gun use than children in other developed countries. One factor that can influence children's interest in guns is exposure to media containing guns.
- Trial name
- NCT03220412
- Testing
- Movies with Guns
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Pediatric Cancer
Mindfulness-based Intervention for Teenagers With Cancer
The purpose of this study is to evaluate the effects of a mindfulness-based meditation intervention on quality of life, sleep and mood in adolescents with cancer compared to a control group.
- Trial name
- NCT01783418
- Testing
- Mindfulness Intervention
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- St. Justine's Hospital
Vaccination Refusal, Communication
Emails Promoting COVID-19 Vaccination Among Healthcare Workers
In this evaluation, two versions of emails will be sent to Geisinger employees who have not been vaccinated against COVID-19. A delayed-contact control group will be emailed after a delay of at least two days.
- Trial name
- NCT04728594
- Testing
- Social Proof, Reframing, Scarcity Message
- Where
- United States
- Volunteers
- 9,566 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Heart Transplant Failure and Rejection
Precision Guided Tacrolimus Dosing in Pediatric Heart Transplant
Immunosuppressive therapy is required to prevent organ rejection, however, dosing of immunosuppressive agents is complicated by patient-specific differences impacting the body's absorption and elimination of these agents.
- Trial name
- NCT04380311
- Testing
- Tacrolimus Dosing Support Tool
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- University of Utah
Type1diabetes
Check It! 2.0: Positive Psychology Intervention for Adolescents With Type 1 Diabetes
The treatment regimen for type 1 diabetes is complex and demanding, and many adolescents have problems with adherence. The proposed study will pilot test a positive psychology intervention for adolescents with type 1 diabetes…
- Trial name
- NCT02984709
- Testing
- Positive Psychology Intervention, Education
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Vanderbilt University
Psychology, Social, Adolescent Behavior
Follow-up Gun Study: Can Safety Videos Mitigate Interest in Guns in Children?
The investigators' previous research has shown that children exposed to media characters with guns in movies and video games are more likely to use real guns themselves (e.g., touch them, hold them, pull the trigger).
- Trial name
- NCT05257837
- Testing
- Gun handling behavior, Debriefing
- Where
- United States
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Acute Graft Rejection, Chronic Allograft Nephropathy
Study Cyclosporine (CsA) Versus Tacrolimus (Tacro) After Campath Induction in Kidney Transplantation
After alemtuzumab induction, followed with kidney transplantation, patients will be randomly assigned to receive either tacrolimus or cyclosporine microemulsion in combination with mycophenolates.
- Conditions
- Acute Graft Rejection, Chronic Allograft Nephropathy, Polyomavirus-related Transplant Nephropathy
- Trial name
- RSCS-Campath (NCT01346397)
- Testing
- cyclosporine or tacrolimus
- Where
- Russia
- Volunteers
- 170 people
- Sponsor
- Russian Academy of Medical Sciences
Type 1 Diabetes Mellitus
Positive Psychology Intervention to Treat Diabetes Distress in Teens With Type 1 Diabetes
The treatment regimen for type 1 diabetes is complex and demanding, and many adolescents experience diabetes distress related to the daily demands of diabetes care, which can cause problems with diabetes management and glycemic…
- Trial name
- T1D (NCT03845465)
- Testing
- Positive Affect + Education, Education
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- Vanderbilt University Medical Center