Clinical trials: Psychopathology
Socioemotional Development, Cognitive Ability
Early Institutionalization Intervention Impact Project
The purpose of this study is to determine the effects of early intervention (placement into foster care, and a caregiving training) on physical, cognitive, social and brain development and psychiatric symptomatology in children…
- Conditions
- Socioemotional Development, Cognitive Ability, Behavioral and Neural Patterns of Attention, Brain Function
- Trial name
- EI-3 (NCT04165746)
- Testing
- Foster Care, Caregiving Intervention
- Where
- Brazil
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Chronic Stress, Anxiety
Preventing Internalizing in Preadolescents Exposed to Chronic Stress
Racial and socioeconomic disparities in physical and mental health problems are large, persistent, and severe; begin during childhood; and stem from in part damage to physiologic stress response systems caused by chronic stress.
- Conditions
- Chronic Stress, Anxiety, Depression
- Trial name
- NCT02764138
- Testing
- Building a Strong Identity and Coping Skills
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Penn State University
Transitional Care, Mental Disorder in Adolescence
Psychiatry of Transition in a World in Transition
This clinical study evaluates risk and protective factor to develop psychopathology in transitional age youth. 300 patients will be recruited at the age of 17 years old and assessed at baseline and 2 years later.
- Conditions
- Transitional Care, Mental Disorder in Adolescence, Mental Health
- Trial name
- Transition_psy (NCT04333797)
- Testing
- Risk and Protective Factors Assessment
- Where
- 4 sites in Belgium
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Queen Fabiola Children's University Hospital
Posttraumatic Stress Disorder (PTSD)
Trajectories of Psychopathology in Response to NET
Narrative Exposure Therapy (NET) has been proven to be effective in the treatment of Posttraumatic Stress Disorder (PTSD) and trauma-related depression in more than a dozen controlled clinical trials.
- Trial name
- TOP-NET (NCT02852616)
- Testing
- Narrative Exposure Therapy
- Where
- Germany
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Konstanz
Bipolar Disorder, Attention Deficit Disorder With Hyperactivity
Brain Imaging and Computer Games in Children With Either Bipolar Disorder, ADHD, Anxiety or Healthy Controls
The purpose of this research is to learn more about how children with mental health problems, including bipolar disorder (BD), attention deficit hyperactivity disorder (ADHD), and generalized anxiety disorder (GAD), differ from…
- Conditions
- Bipolar Disorder, Attention Deficit Disorder With Hyperactivity, Attention Deficit Disorder Without Hyperactivity, Generalized Anxiety Disorder
- Trial name
- BBPP (NCT01570426)
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Bradley Hospital
Early Intervention, Child of Impaired Parents
VIA Family - Family Based Early Intervention Versus Treatment as Usual
This RCT aims to investigate the effect of an early family-based intervention (VIA Family) focusing on reducing risk and increasing resilience for children in families where at least one parent has a severe mental illness.The…
- Conditions
- Early Intervention, Child of Impaired Parents, Child, Adolescent
- Trial name
- NCT03497663
- Testing
- VIA Family intervention, Treatment As Usual
- Where
- Denmark
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Eating Disorders in Adolescence, Eating Disorders in Children
A Study of the Intestinal Microbiota in Children and Adolescents With Eating Disorders. A Perspective From Psychoneuroimmunology
The goal of this observational study is to learn if behavioral and psychological factors are associated with the intestinal microbiota composition and function in children and adolescents with eating disorders (ED).
- Trial name
- PSYNIGED (NCT07066033)
- Where
- 2 sites in Spain
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Esther Nova
HIV Infections, Mental Disorders
Psychiatric Problems in Children and Adolescents Infected With HIV at Birth
The purpose of this study is to determine whether HIV and anti-HIV drugs cause mental health problems or make mental health problems worse in children and adolescents who were infected with HIV at birth.
- Trial name
- NCT00100542
- Testing
- Psychiatric interviews
- Where
- 32 sites in United States, Puerto Rico
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- International Maternal Pediatric Adolescent AIDS Clinical Trials Group
Child Maltreatment, Interpersonal Relations
Beneficial or Fostering Future Struggles (B.F.F.s)? Characterizing the Role of Friends in the Development of 13- to 17-Year-Old Adolescents
The goal of this clinical trial is to investigate how the friendship experiences of maltreated (i.e., abused and/or neglected) and non-maltreated adolescents differentially influence their risk for adverse outcomes.
- Conditions
- Child Maltreatment, Interpersonal Relations, Victimisation, Psychopathology
- Trial name
- BFFs (NCT05893459)
- Testing
- Debrief
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Psychopathology
Virtual Mom Power With High-Adversity Mothers and Children (MPHAMC)
This study is a randomized controlled confirmatory efficacy trial of virtual Mom Power (MP), a group-based, relationship-focused multifamily preventive intervention.
- Trial name
- NCT05129397
- Testing
- Mom Power, Mom Power Informational Mailing
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Tulane University
Adolescent, Psychopathology
An Evidence-based Family Support Program for Parents and Children in Palestine: A Theory-based Intervention
Few evidence-based programs exist to support children and families affected by sociopolitical conflict, despite documented evidence of their heightened risk for emotional and behavioral adjustment problems associated with…
- Conditions
- Adolescent, Psychopathology, Parent-Child Relations, Violence
- Trial name
- NCT05706376
- Testing
- Promoting Positive Family Futures, Treatment as Usual
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of Notre Dame
Bipolar Disorder, Involutional Depression
Study of the Psychological Development of Children of Parents With and Without Affective Disorders
This research study is the continuation of a study started more than 20 years ago. The study was designed to explore the effect that depressed parents have on their children and to better understand the factors that contribute to…
- Conditions
- Bipolar Disorder, Involutional Depression, Mood Disorder
- Trial name
- NCT00001170
- Where
- United States
- Volunteers
- 1,045 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Emotional Problem, Behavior Problem
Enhancement of Emotion Regulation Skills in Adolescents
For the current study, a prevention program is developed and applied to enhance the emotion regulation skills of adolescents. Before and after the application of the prevention program, all participants will be assessed for their…
- Trial name
- NCT04001140
- Testing
- Enhancement of emotion regulation skills
- Where
- Cyprus
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Cyprus
Distress, Emotional, Internalizing Mental Health Symptoms
Piloting a School-Based Distress Tolerance Skills Program for Adolescents
Research suggests that an individual's perceived ability to withstand distressing or upsetting emotions (i.e., distress tolerance; DT) is a common risk factor across several mental health conditions that commonly emerge during…
- Trial name
- STRIDE (NCT06638853)
- Testing
- Distress Tolerance Skills Training
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Chromosome 22q11.2 Deletion Syndrome
Genetics and Psychopathology in the 22q11 Deletion Syndrome
The purposes of this study are to: 1. study the nature and longitudinal course of psychiatric symptoms in children with the 22q11.2 deletion syndrome and 2. identify genes that contribute to the occurrence of these symptoms.
- Trial name
- NCT00161109
- Where
- 2 sites in United States, Netherlands
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Medical Education
Add-on Video-based Training on Mental Status Examination Skills
The goal of this clinical triall is to investigate the training effect of access to authentic patient video on mental status examination performance among 5th year Danish medical students.
- Trial name
- VV-RCT (NCT05795387)
- Testing
- Video-based self-regulated training on the mental status exam, E-course with written material on the mental status exam
- Where
- 2 sites in Denmark
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Psychiatric Research Unit, Region Zealand, Denmark
Personality Disorder
An Evolutionarily Informed Conceptualization of Personality Pathology
The purpose of this study is to explore the reliability of a new evolutionarily-informed model for conceptualizing personality pathology.
- Trial name
- EIC-PP (NCT06623838)
- Testing
- Evolutionarily informed case conceptualization
- Where
- Italy
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Tages Onlus
Rejection Sensitivity, Puberty
Rejection Sensitivity and Puberty in Mental Health Vulnerability to Social Media Experiences in Early Adolescent Girls
This longitudinal study is designed to test bidirectional relationships between preteen girls' mental health and social media experiences.
- Conditions
- Rejection Sensitivity, Puberty, Psychopathology
- Trial name
- NCT06777823
- Testing
- Social Rejection Task
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Anxiety Symptoms, Depressive Symptoms
Effects of a Single-session Implicit Theories of Personality Intervention on Early Adolescent Psychopathology
The goal of the project is to test whether a single-session intervention teaching incremental theories of personality, or the belief that one's personality is malleable, can strengthen recovery from social stress and reduce the…
- Trial name
- NCT03132298
- Testing
- Implicit Theories of Personality Program, Control Program
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Harvard University
Developmental Psychological Disorder
Developmental Psychopathology and the Gene-environment Interaction
The present is a followup study that aims at investigating the effect of genetic and environmental factors on the possible development of psychopathological conditions in a longitudinal perspective.
- Trial name
- TwinAger (NCT04489069)
- Testing
- MRI, Clinical and Neuropsychological evaluations, Drawing DNA sample
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea