Clinical trials: Puerperal Disorders
HIV
Clinical Study of an Aluvia-based HAART Regimen for Prevention of Mother-to-child HIV Transmission in Africa
Therapeutic options to prevent vertical transmission of HIV remain limited. Combination antiretroviral therapy in the form of HAART (Highly Active Anti Retroviral Therapy) is generally recommended in the developed world, both for…
- Trial name
- NCT01088516
- Testing
- Lopinavir/Ritonavir (200/50 mg) Tablets + Zidovudine + 3TC
- Where
- Zambia
- Volunteers
- 280 people
- Sponsor
- University of Zambia
Immunization; Infection
Mobile Phone Reminders (and Photovoice) for Routine Immunization in Nigeria - The MOPING Study
This study aims to implement and test the efficacy of photovoice, Short Messaging Service (SMS) and phone call reminders in improving childhood immunization coverage (uptake, timeliness and completion rates) and reducing…
- Trial name
- MOPING (NCT03402646)
- Testing
- Reminder module (SMS and Phone call), Photovoice
- Volunteers
- 1,813 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Postpartum Hemorrhage, Pregnancy
RCT of Misoprostol for Postpartum Hemorrhage in India
Death rates for pregnant women in rural India are approximately forty-five times higher than in the United States. Bleeding after the birth of a child and underlying anemia are the primary causes of mothers' deaths and sickness…
- Trial name
- NCT00097123
- Testing
- Misoprostol
- Where
- India
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Pregnancy, Childbirth and Puerperal Disorders
Effects of Pregnancy and Childbirth on Pelvic Floor Morphology and Sexual Function in Egyptian Women
To evaluate levator ani muscle morphology following normal vaginal delivery and cesarean section (elective and emergent), using three-dimensional (3D) transperineal ultrasound, and to study the effect of mode of delivery on…
- Trial name
- NCT02245386
- Testing
- transperineal pelvic floor ultrasound
- Volunteers
- 120 people
- Sponsor
- Al-Azhar University
Postpartum Depression
Mother-Infant Intervention for Postpartum Depression and Associated Mother-Infant Relationship Dysfunction
Maternal depression and mother-infant relationship dysfunction have reciprocal effects on each other. An integrated approach addressing both problems simultaneously may improve outcomes.
- Trial name
- NCT02057627
- Testing
- Perinatal Dyadic Psychotherapy
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Spaulding Rehabilitation Hospital
Depression, Postpartum
Cerebral Synchronization Between Mothers and Their Newborns During Breastfeeding
Different reciprocal positions of mother and newborn during breastfeeding may be adopted. Other than the one derived from UNICEF guidelines, or standard position, an approach called biological nurturing has been recently…
- Trial name
- NCT05821569
- Testing
- Standard approach, Biological nurturing
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Burlo Garofolo
Preeclampsia
Postpartum Hemorrhage Prevention in Patients With Preeclampsia (PHP3 Study)
Evaluation of the efficacy of postpartum 24 hour oxytocin infusion to reduce blood loss in patients with pre-eclampsia (PE)
- Trial name
- PHP3 (NCT02221830)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Colorado, Denver
Congenital Heart Disease
Parenting After Infant Congenital Heart Defect Diagnosis
The purpose of this research study is to learn about parents' experiences following diagnosis of a fetal/neonatal Congenital Heart Defect (CHD).
- Trial name
- NCT01503307
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Medical College of Wisconsin
Postpartum Depression
The Effect of Early Dyadic Psychotherapy for Mothers Suffering From PPD on Oxytocin Level and on Childrens' Emotional Development
Background: Postpartum depression follows approximately 10-15% of deliveries. Maternal functional disability, particularly in the relationship with the infant, a hallmark of PPD, causes impairment in the mother's ability to bond…
- Trial name
- NCT04138368
- Testing
- dyadic psychotherapeutic intervention, supportive intervention
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- HaEmek Medical Center, Israel
Postpartum Hemorrhage
Misoprostol for the Treatment of Postpartum Hemorrhage
The purpose of this study is to test whether misoprostol is as effective as oxytocin for treating primary postpartum hemorrhage (PPH) with uterine atony as the suspected cause in two circumstances: 1) where women have received…
- Trial name
- NCT00116350
- Testing
- Misoprostol, Oxytocin
- Where
- 6 sites in Burkina Faso, Ecuador and 3 more
- Volunteers
- 1,786 people
- Sponsor
- Gynuity Health Projects
Antepartum Hemorrhage, Postpartum Hemorrhage
Strengthening Maternal Neonatal and Child Health Services in a Rural District of Pakistan
The Maternal Neonatal and Child health indicators in District Dadu of Pakistan portrays a dismal pictures and after the floods of 2010-2011 the health infrastructure of this district was badly affected.
- Conditions
- Antepartum Hemorrhage, Postpartum Hemorrhage, Anemia, Eclampsia
- Trial name
- SRC (NCT02797353)
- Testing
- Maternal Neonatal and Child Health Interventions
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Gestational Diabetes, Type 2 Diabetes Mellitus
Face-it: Health Promotion for Women With Prior Gestational Diabetes
This project focuses on evaluating a health promotion intervention among families where the mother has prior gestational diabetes mellitus (GDM) in the first year after delivery.
- Conditions
- Gestational Diabetes, Type 2 Diabetes Mellitus, Quality of Life
- Trial name
- Face-it (NCT03997773)
- Testing
- Face-it Intervention
- Where
- 3 sites in Denmark
- Volunteers
- 277 people
- Sponsor
- Steno Diabetes Center Copenhagen
Breastfeeding, Ankyloglossia
Physiotherapy in the Treatment of Breastfeeding Difficulties
The objective of this randomized, single-blind clinical trial is to compare the efficacy of two treatments (Myofunctional Therapy and breastfeeding sessions) in infants who have difficulty breastfeeding during the first week of…
- Conditions
- Breastfeeding, Ankyloglossia, Lactation Disorders
- Trial name
- NCT05843279
- Testing
- Myofunctional therapy
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Universidad de Almeria
Postpartum Bleeding
When and How to Administer Oxytocin for Active Management of Third Stage of Labour
To compare the efficacy of the route and timing of oxytocin administration for Active management of third stage of labour (AMTSL).
- Trial name
- NCT01954186
- Testing
- intravenous & intramuscular oxytocin, after delivery of the fetus & when anterior shoulder seen
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people
- Sponsor
- Etlik Zubeyde Hanim Womens' Health and Teaching Hospital
Herpes Simplex, Pregnancy
A Study of HSV Testing Among Pregnant Women
The objective of the study is to evaluate the acceptance and effect of type- specific HSV serologic testing of pregnant women on sexual behavior at the end of pregnancy.
- Trial name
- NCT00194415
- Testing
- Safer-sex counseling, Type specific serologic HSV testing
- Where
- Canada
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- University of Washington
Pregnancy Hemorrhage, Postpartum Hemorrhage
Implementation of the NPMS Obstetric Hemorrhage Bundle at a Tertiary Center: Utilization of the Delphi Method
The National Partnership for Maternal Safety (NPMS) developed an obstetric hemorrhage consensus bundle to provide every United States birthing facility consistent, validated practice guidelines.
- Trial name
- NCT03018119
- Testing
- Survey
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Hypertension
NSAID Use in Postpartum Hypertensive Women
Women who have the diagnosis of hypertension (pre-pregnancy and pregnancy induced) and deliver an infant via vaginal delivery will be placed into two groups in the postpartum period.
- Trial name
- NCT02902172
- Testing
- Acetaminophen, NSAID
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Postpartum Depression, Quality of Life
Whether Probiotics Use in Neonate and Infant Improve Their Mother's Life Quality
Postpartum depression and poor quality of life during postpartum were an vital issue in recent years. Infant's health condition was thought to be a possible reasons related mother's postpartum quality of life, and functional…
- Conditions
- Postpartum Depression, Quality of Life, Functional Gastrointestinal Disorders, Probiotics
- Trial name
- NCT04741971
- Testing
- Probiotics group, Non-probiotics group
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Buddhist Tzu Chi General Hospital
Healthy Diet, Health Behaviour
Effectiveness of Educational Intervention on Sustainable Breastfeeding: The GREEN MOTHER Project
Breastfeeding is the healthiest form of nutrition for the baby and is recommended to use exclusive breastfeeding (EB) until 6 months.
- Conditions
- Healthy Diet, Health Behaviour, Environmental-Pollution-Related Condition, Mothers
- Trial name
- NCT05729581
- Testing
- The educational programme on sustainable and healthy diet and breastfeeding
- Where
- Spain
- Volunteers
- 429 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Infant Development, Breastfeeding
The Effects of Massage Therapy on Term Neonates Development and on Maternal Bonding
This study collects data from 2 groups of mother- term neonate pairs at the Neonatal Department of Children Hospital II, Ho Chi Minh City (in group M: neonates are massaged by their mothers during the first 2 months after birth…
- Conditions
- Infant Development, Breastfeeding, Postnatal Depression
- Trial name
- NCT04285437
- Testing
- infant massage
- Where
- Vietnam
- Volunteers
- 120 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City