Clinical trials: Pulmonary Disorder, Chronic Obstructive
Cystic Fibrosis Lung, Respiratory Infections, Recurrent, Chronic
A Double-Blind, Active-Controlled, Multiple-Ascending Dose Study of Aerosolized RSP-1502 in Subjects With CF and Chronic PA Lung Infection
A double-blind, active-controlled, multiple-ascending dose, safety study of aerosolized RSP-1502 in subjects with cystic fibrosis Pseudomonas aeruginosa lung infection.
- Conditions
- Cystic Fibrosis Lung, Respiratory Infections, Recurrent, Chronic, Pseudomonas Aeruginosa
- Trial name
- NCT06016088
- Testing
- RSP-1502, Tobramycin inhalation solution
- Where
- 22 sites in United States, Australia
- Volunteers
- 71 people
- Sponsor
- Respirion Pharmaceuticals Pty Ltd
Chronic (> 2 Weeks) Critical Ischemia With Skin Defect in Lower Limbs
Viennese Registry on Patients With Chronic Critical Limb Ischemia
The rationale of this study is to establish a registry to detect and follow patients with CLI treated in Vienna. The Vienna CLI registry is meant to document the incidence, prevalence, and actual outcome of CLI patients in a real…
- Trial name
- NCT01233141
- Where
- Austria
- Volunteers
- 400 people
- Sponsor
- Medical University of Vienna
Chronic Obstructive Pulmonary Disease
Physical Activity Counseling During Pulmonary Rehabilitation
This randomized controlled trial will assess the effect of adding intensive physical activity counseling to an outpatient pulmonary rehabilitation program.
- Trial name
- PAC (NCT00948623)
- Testing
- physical activity counseling program
- Where
- Belgium
- Volunteers
- 70 people
- Sponsor
- KU Leuven
Acute Exacerbation of COPD
Non Invasive Ventilation With NAVA vs ASV for AECOPD
Non invasive ventilation is the standard of care in managing patients with exacerbation of chronic obstructive pulmonary disease.
- Trial name
- NCT04414891
- Testing
- Non invasive ventilation
- Where
- India
- Volunteers
- 76 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Chronic Obstructive Pulmonary Disease
Effect of Remote Physiologic Monitoring (RPM) on Outcomes in COPD Patients
This pre/post study was a retrospective analysis of unplanned hospitalization rates in a cohort of COPD subjects started on remote physiologic monitoring (RPM) at a large, outpatient pulmonary practice.
- Trial name
- NCT05518981
- Testing
- Respiratory Remote Patient Monitor (Spire Health Tag)
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Spire, Inc.
Cancer, Heart Failure
Virtual Reality as an Adjunct to Management of Pain and Anxiety in Palliative Care
Virtual reality has been shown to be an effective way to treat pain and anxiety in various different settings. Palliative care is an area of medicine that often deals with patients suffering from pain and anxiety.
- Conditions
- Cancer, Heart Failure, Copd, ALS
- Trial name
- NCT04138095
- Testing
- Virtual Reality
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Riverview Health Centre
Asthma
Chronic Asthma Study in 2- to 5-Year-Old Patients (MK0476-072 )
A study in 2-5 year old children to evaluate the safety and tolerability of montelukast and placebo administered once daily at bed time.
- Trial name
- NCT00968201
- Testing
- montelukast sodium
- Volunteers
- 689 people
- Sponsor
- Organon and Co
Systemic Juvenile Idiopathic Arthritis
Study of Efficacy and Safety of Canakinumab in Japanese Patients With SJIA
This was a phase III study designed to provide efficacy and safety data for canakinumab administered for at least 48 weeks as subcutaneous (s.c.) injection every 4 weeks (q4wk) in Japanese patients with Systemic Juvenile…
- Trial name
- NCT02396212
- Testing
- Canakinumab
- Where
- 7 sites in Japan
- Volunteers
- 19 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Obstructive Pulmonary Disease, COPD
Do Blood Tests Help to Decide Which Patients With Flares of Chronic Obstructive Pulmonary Disease (COPD) Need Antibiotics and Steroids?
The goal of this clinical trial is to see if the use of two simple blood tests: C reactive protein and eosinophils, can reduce the use of steroids and antibiotics in patients with flares of chronic obstructive pulmonary disease…
- Conditions
- Chronic Obstructive Pulmonary Disease, COPD, Exacerbation of COPD, AECOPD
- Trial name
- Bidex (NCT06929767)
- Testing
- biomarker-guided decision making, GOLD recommendations
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Ottawa Hospital Research Institute
Hypertension, Diabetes
Development and Testing of a Sub-district Specific Model of 'Whole-of-government', and 'Whole-of-society' Approaches for the Prevention and Control of Non-communicable Diseases in a Sub-district of Bangladesh
Globally, non-communicable diseases (NCDs) are the leading cause of both mortality and morbidity. This intervention study aims to prevent and manage NCDs by adopting the World Health Organization's (WHO) comprehensive…
- Conditions
- Hypertension, Diabetes, Asthma, Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- NCT06453382
- Testing
- Behavioural change modification, Screening, NCD related knowledge practice and attitude
- Where
- Bangladesh
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- BRAC University
Chronic Obstructive Pulmonary Disease, COPD
The Effect of Breathing Helium-Hyperoxia During Pulmonary Rehabilitation in Patients With COPD
The purpose of this study is to examine whether breathing helium-hyperoxia during exercise in a pulmonary rehabilitation program can improve the exercise tolerance and health related quality of life of patients with Chronic…
- Conditions
- Chronic Obstructive Pulmonary Disease, COPD, Emphysema, Lung Diseases
- Trial name
- NCT00406705
- Testing
- Helium-Hyperoxia
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- University of Alberta
Acute-graft-versus-host Disease, Chronic Graft-versus-host-disease
Study of Ruxolitinib for Acute and Chronic Graft Versus Host Disease
While hematopoietic stem cell transplant (HSCT) is an effective therapy, graft versus host disease (GVHD) is the most significant complication after HSCT.
- Conditions
- Acute-graft-versus-host Disease, Chronic Graft-versus-host-disease, Solid Organ Transplant
- Trial name
- NCT05121142
- Testing
- Ruxolitinib
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Asthma (Diagnosis)
Chronic Effects of Photobiomodulation With an LED Vest on Functional Capacity, Inflammatory Markers, and Muscle Perfusion in Children With Asthma
Asthma is a chronic inflammatory disease of the airways that results in tissue remodeling, airflow limitation, and bronchial hyperresponsiveness.
- Trial name
- Asthma PBM (NCT07613671)
- Testing
- Photobiomodulation, Exercise
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Nove de Julho
Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive
Is the Short Physical Performance Battery a Useful Outcome Measure in Chronic Obstructive Pulmonary Disease
Patients with Chronic Obstructive Lung Disease (COPD) often develop muscle problems, particularly in their legs which makes them more limited in what they can do.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive, Pulmonary Emphysema, Bronchitis, Chronic
- Trial name
- NCT01515709
- Where
- United Kingdom
- Volunteers
- 445 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Asthma
Effects of Particle Size in Small Airways Dysfunction
The airways in the lungs get smaller the further into the lungs they go. Most simple measurements of lung function only reflect the larger 'central' airways and do not provide information on the smaller 'peripheral' airways.
- Trial name
- MAN03 (NCT01892787)
- Testing
- Formoterol, Salmeterol
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- University of Dundee
COPD
Case Method Education on COPD to General Practitioners
Background: COPD is an inflammatory and chronic obstructive lung disease, mainly caused by smoking. Most patients with COPD are discovered and treated in primary health care.
- Trial name
- PRIMAIR (NCT02213809)
- Testing
- Case method education in COPD, Traditional education in COPD
- Where
- Sweden
- Volunteers
- 822 people
- Sponsor
- Karolinska Institutet
Pediatric Feeding Disorder, Chronic, Avoidant Restrictive Food Intake Disorder
The Use of Cyproheptadine in Pediatric Feeding Disorders
The goal of this clinical trial is to learn if Cyproheptadine, an appetite stimulant, can improve eating habits in children with Pediatric Feeding Disorders.
- Trial name
- NCT06751290
- Testing
- Cyproheptadine, Nutritional Counseling, Behavioral Counseling
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Miami
Asthma in Children, Protracted Bacterial Bronchitis
Biomarkers and Respiratory Omics as New CHildren Opportunities - Study of Clinical Outcomes and Predictivity Evaluation
The goal of this observational study is to improve the identification of biomarkers that predict disease progression and to assess the effectiveness of current therapies in children with asthma and protracted bacterial…
- Conditions
- Asthma in Children, Protracted Bacterial Bronchitis, Chronic Cough
- Trial name
- BRONCHOSCOPE (NCT07232550)
- Testing
- fiberoptic bronchoscopy, blood sample collection, Respiratory functional tests
- Where
- Poland
- Volunteers
- 160 people
- Sponsor
- Medical University of Warsaw
Chronic Obstructive Pulmonary Disease (COPD)
Management of Patients With Respiratory Symptoms in Sweden
This is a web-based randomized survey to evaluate management of respiratory symptoms among physicians in Sweden. The aim of this study is to determine if there is a gender bias in the diagnosis of COPD and how often physicians…
- Trial name
- NCT02728674
- Testing
- Person in the case is a male., Person in the case is a female., Symptom in the case is breathlessness.
- Where
- Sweden
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Skane University Hospital
Asthma
Extended Safety Study of Montelukast in Infants and Young Children With Chronic Asthma (0476-232)
Patients were treated with either montelukast 4 mg oral granules or usual care. Patients who completed Protocol MK0476-176-01 (NCT00943683) had the option to enroll in this study.
- Trial name
- NCT00943397
- Testing
- montelukast sodium, Comparator: Usual Care
- Volunteers
- 190 people
- Sponsor
- Organon and Co