Clinical trials: Pulmonary Function
Adhd, ALS
National Multicenter Interventional Study Aimed at Evaluating the Effect on the Intestinal Microbiota in Chronically Frail Patients Who Share Alterations in Intestinal Function.
The objective of the study will be to understand whether a supplementation of the diet with an active symbiotic, i.e. characterized by a mix of probiotics and a specially selected fiber with prebiotic activity combined with a…
- Conditions
- Adhd, ALS, Bronchial Asthma
- Trial name
- sPATIALS3 (NCT06005506)
- Testing
- Prebiotic fiber, Dietary fiber, Probiotic
- Where
- 4 sites in Italy
- Volunteers
- 64 people
- Sponsor
- Institute of Biomedical Technologies-National Research Council, Italy
Pulmonary Regurgitation After Repair of Tetralogy of Fallot
Tetralogy of Fallot Seed Grant
Patients with pulmonary regurgitation after surgical correction of ToF over 13 years old will be recruited from the UCSF adult congenital heart disease clinic.
- Trial name
- NCT00722826
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of California, San Francisco
Migraine Disorders, COVID-19 Pandemic
The Impact of nCoV-2019 on Children With Migraine
Executive functions, anxiety and their relation to social participation and quality of life among children with Migraine during COVID-19 Backgrounds: Among children, especially adolescents, migraine stands out as one of the most…
- Trial name
- NCT06077006
- Testing
- questionnaires Only
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Bnai Zion Medical Center
Leiomyomatosis
Official Record of Patients Diagnosed With Lymphangioleiomyomatosis (LAM)
Pulmonary lymphoangioleiomyomatosis (LAM) is a rare destructive lung disease typically affecting women of childbearing age. Currently, there is no effective therapy for the disease and the prognosis is poor.
- Trial name
- NCT00001869
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Mesothelioma, Lung Neoplasms
Chest Wall Motion Analysis in Disease
Breathing movements, called chest wall motion, are very complex. The investigators are studying how movement of the abdomen, ribs and diaphragm contribute to breathing and how this differs with different diseases in the chest.
- Conditions
- Mesothelioma, Lung Neoplasms, Surgery, Cystic Fibrosis
- Trial name
- CWM (NCT02958683)
- Testing
- Chest wall motion analysis
- Where
- United Kingdom
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Heart of England NHS Trust
Asthma
Effect of an add-on Treatment With Ivy Leaves Dry Extract on Lung Function in Bronchial Asthma
The trial aims to record possible effects of a supplementary treatment with ivy leaves dry extract on different lung function parameter, on bronchial hyperreactivity, on individual markers of asthmatic inflammation and on the…
- Trial name
- HeHe (NCT01692041)
- Testing
- ivy leaves dry extract
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Technische Universität Dresden
Cystic Fibrosis
Cystic Fibrosis and Endothelial Function: At Rest and During Exercise
Perhaps one of the most disturbing aspects of Cystic Fibrosis (CF) is the associated premature death. Oxidative stress has been observed in patients with CF and exercise intolerance has been shown to predict mortality in patients…
- Trial name
- NCT01772758
- Testing
- BH4 5mg, BH4 20mg, Antioxidant Cocktail
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Augusta University
Respiratory Failure, Covid19
COVID-19 Advanced Respiratory Physiology (CARP) Study
The anticipated second wave of COVID-19 cases will present healthcare system challenges, including requirement to monitor large numbers of patients for deteriorating respiratory failure.
- Conditions
- Respiratory Failure, Covid19, Biosensor
- Trial name
- CARP (NCT04668313)
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- NHS Greater Glasgow and Clyde
Bronchopulmonary Dysplasia, Necrotizing Enterocolitis
Effects of Delayed Cord Clamping in Very Low Birth Weight Infants
The purpose of this study was to see if a brief delay in cord clamping for 30 to 45 seconds would result in higher hematocrit levels, fewer transfusions, healthier lungs, and better motor function at 40 wks and 7 months of age.
- Conditions
- Bronchopulmonary Dysplasia, Necrotizing Enterocolitis, Intraventricular Hemorrhage, Late Onset Neonatal Sepsis
- Trial name
- NCT00840983
- Testing
- delayed cord clamping
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Rhode Island
Cystic Fibrosis in Children
Determinants of Early Cystic Fibrosis Lung Disease
The overall objective of this study is to determine the impact early nutritional and respiratory indices have on early CF lung disease.
- Trial name
- NCT03579173
- Testing
- Infant PFT, Lung Clearance Index, Passive tidal breathing
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Indiana University
Left Ventricular Hypertrophy
Postnatal Steroids Effects on Cardiac Function in Extremely Preterm
Hypothesis/Study question In infants born at less than 29 weeks of estimated gestational age, what are the effects of dexamethasone use on cardiac structure/performance and lung water content? Study objectives To measure effects…
- Trial name
- SPEC (NCT04644094)
- Testing
- Echocardiography (ECHO) and lung ultrasound (LUS) studies before and after Dexamethasone administration
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Coronary Artery Disease, Obesity
Structured Physiotherapy Program in Obese and Non-obese Patients
A routine physiotherapy program has been shown to be effective in the prevention and treatment of cardiopulmonary diseases. It also significantly increases functional capacity following coronary artery bypass grafting.
- Trial name
- NCT05357937
- Testing
- standard physiotherapy program
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- University of Jazan
Pulmonary Stenosis
Pulmonary Arteriopathy-Diagnostics and Therapy
Postoperative stenoses of the pulmonary artery vascular system seldom occur alone; they are frequently found in connection with congenital heart defects or malformation syndromes.
- Trial name
- NCT00266175
- Where
- 5 sites in Germany
- Volunteers
- 53 people
- Sponsor
- Competence Network for Congenital Heart Defects
Cystic Fibrosis
LBM & Lung Function in Adolescents With CF
In patients with cystic fibrosis (CF) the commonest cause of death is respiratory failure. Respiratory failure can have many causes.
- Trial name
- NCT02797912
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 29 people
- Sponsor
- King's College Hospital NHS Trust
Bronchopulmonary Dysplasia
MRI of Lung Structure and Function in Preterm Children
The MRI tools developed by the investigators are well positioned for assessing regional changes in lung structure and function in preterm children with bronchopulmonary dysplasia (BPD), in which airway limitation similar to…
- Trial name
- NCT03475264
- Testing
- Lung MRI
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
High-altitude Training Adaptations in Adolescent Male Rowers
Effects of a 4-Week Altitude Training on Sport-Specific Performance, Body Composition, and Cardiac and Pulmonary Function in Adolescent Male Rowers
This study aims to investigate the effects of a 4-week altitude training program on adolescent male rowers. The research will examine changes in athletic performance, athletic body composition, athletic cardiac function, athletic…
- Trial name
- NCT07612956
- Testing
- 4-Week Altitude Training
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Macao Polytechnic University
Kidney Transplant
A Study of Factors That Affect Long-Term Kidney Transplant Function
The causes of deterioration of transplanted kidney function are poorly understood. The purpose of this study is to determine the disease processes that cause transplanted kidney dysfunction and loss in patients who received a…
- Trial name
- DeKAF (NCT00270712)
- Where
- 7 sites in United States, Canada
- Volunteers
- 3,175 people
- Sponsor
- University of Minnesota
Esophageal Atresia, Oesophageal Atresia
Evaluation of the Respiratory Impact After Conventional or Minimally Invasive Esophageal Atresia Surgery
Right thoracotomy, conventional approach to esophageal atresia repair, leads to up to 60% radiological chest wall sequelae anomalies. The impact of these anomalies on the patient's respiratory function remains unknown.
- Conditions
- Esophageal Atresia, Oesophageal Atresia, Restrictive Lung Disease, Chest Wall Anomaly
- Trial name
- RestriMIS (NCT04136795)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Angers
Covid19
Respiratory Muscle Strength in Volleyball Players Suffered From COVID-19
In literature, there is no data evaluating respiratory functions in volleyball players during Covid-19 pandemic. The aim of this study is to evaluate and compared pulmonary functions, respiratory muscle strength, body…
- Trial name
- NCT04789512
- Testing
- Respiratory functions
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Gazi University
Cystic Fibrosis
Combined Inspiratory Muscle and 'Whole Muscle' Training in Children With Cystic Fibrosis
To study the effects of an 8-week combined inspiratory muscle training and exercise (resistance+aerobic) program on of a lung volume, inspiratory muscle strength (maximal inspiratory pressure, PImax) and cardiorespiratory fitness…
- Trial name
- NCT01706445
- Testing
- Other
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidad Europea de Madrid