Clinical trials: Pulmonary Function
Cystic Fibrosis
A Study to Evaluate ELX/TEZ/IVA on Cough and Physical Activity in Participants With Cystic Fibrosis (CF)
This study will evaluate the effects of elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA) on cough and physical activity using wearable technology in CF participants.
- Trial name
- NCT04969224
- Testing
- ELX/TEZ/IVA, IVA
- Where
- 19 sites in Australia, Belgium and 2 more
- Volunteers
- 82 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
COPD (Chronic Obstructive Pulmonary Disease)
Effects of Alternate Nostril Breathing and Bellows Breath in COPD Patients
COPD is a common respiratory disease characterized by progressive airflow obstruction, dyspnea, chronic cough, and sputum production.
- Trial name
- NCT07719192
- Testing
- alternate nostril breathing, bellows breath
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Asthma
Impact of Educational Intervention Protocol on the Level of Knowledge, Clinical Control and Lung Function of People With Asthma
The goal of this randomized controlled clinical trial is to evaluate the effects of a proposed educational intervention on people with asthma.
- Trial name
- NCT06878352
- Testing
- Educational intervention BUNDLE, prepared in accordance with the recommendations of the Global Initiative for Asthma- GINA (2024)).
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- Federal University of Paraíba
Pulmonary Tuberculoses, Pulmonary Function; Newborn, Abnormal
Lung Health After Tuberculosis: Clinical and Functional Assessment in Post Pulmonary Tuberculosis Egyptian Patients.
Some of pulmonary tuberculous patients who completed their medication course experience lung function impairment
- Trial name
- NCT05097638
- Testing
- spirometry
- Where
- Egypt
- Volunteers
- 210 people
- Sponsor
- Assiut University
Asthma
Intervention Study to Improve Adherence in Asthma
We wanted to investigate if it was possible to improve adherence to prescriptions and advice in pre-school children with newly diagnosed asthma.
- Trial name
- NCT00516633
- Testing
- Extra information and support
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Värmland County Council, Sweden
High Altitude Pulmonary Hypertension
Right Ventricular Function During Exercise in Highlanders/Lowlanders
The purpose of the current study is to evaluate the right ventricular function during graded cycling on an ergometer by transthoracic echocardiography in Kyrgyz highlanders with high altitude pulmonary hypertension (HAPH) by…
- Trial name
- NCT03165032
- Where
- Kyrgyzstan
- Volunteers
- 173 people
- Sponsor
- University of Zurich
Over Weight, School Age Children
Structured Wii Aerobic Protocol on Reaction Time and Pulmonary Functions in Over Weight School- Aged Children
Childhood overweight have emerged as major global health concerns and are linked to lower pulmonary functions and reaction time levels among school-aged children.
- Trial name
- NCT07513298
- Testing
- The Nintendo Wii Fit operates on the Wii system, produced by Nintendo Co., Ltd, based in Kyoto, Japan., Chest physical therapy and diet therapy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Zaytoonah University of Jordan
COPD Exacerbation, COPD
Impulse Oscillometry in COPD Exacerbation
This study aimed to evaluate small airway function during ECOPD and recovery periods using IOS. In this prospective single-center study, patients with ECOPD underwent evaluation of their pulmonary functions using IOS and…
- Trial name
- NCT07185581
- Testing
- Impulse Oscillometry
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Deniz Bilici
Acute Lymphoblastic Leukemia, Hodgkin Disease
Imaging of Chemotherapy-induced Morphological and Functional Lung Changes in Childhood ALL and HD
With increasing cure rates of childhood cancer there is growing recognition of late effects of treatments. However, there is a lack of non-invasive and child-friendly procedures that can indicate possible late damage.
- Conditions
- Acute Lymphoblastic Leukemia, Hodgkin Disease, Allogeneic Stem Cell Transplantation
- Trial name
- MinimALL (NCT06093334)
- Testing
- Low-field magnetic resonance imaging, Cardiopulmonary testing, Pulmonary testing
- Where
- Germany
- Volunteers
- 27 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Lung Cancer, Ventricular Failure, Right
Right Side of Heart Function After Lung Surgery
The purpose of this study is explore the impact of lung cancer surgery on the function of the right side of the heart.
- Trial name
- NCT01892800
- Testing
- Lung resection
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- University of Glasgow
Asthma
Fenzian Asthma Multicenter Outcomes Study
The purpose of this study is to investigate the effects of Fenzian™ treatment on symptoms (such as shortness of breath), lung function (how well the lungs work), and albuterol/salbutamol (rescue medication) use in people with…
- Trial name
- FAMOUS (NCT00784758)
- Testing
- Fenzian Device
- Where
- 6 sites in United States, South Africa and 1 more
- Volunteers
- 81 people
- Sponsor
- University of California, Los Angeles
Scoliosis; Idiopathic, Infantile, Scoliosis; Juvenile
Physical Activity, Motor Competence, Pulmonary Function, and Quality of Life in Children With Severe Spinal Disease
Observation study about physical activity, motor competence, pulmonary function, and health related quality of life in children, surgically treated for early onset scoliosis
- Conditions
- Scoliosis; Idiopathic, Infantile, Scoliosis; Juvenile, Scoliosis Neuromuscular, Scoliosis in Neurofibromatosis
- Trial name
- NCT03494829
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Oslo University Hospital
Muscular Dystrophies, Muscular Dystrophy, Duchenne
A Study of CAP-1002 in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy
HOPE-2 is a double-blind clinical trial evaluating the safety and efficacy of a cell therapy called CAP-1002 in study participants with Duchenne Muscular Dystrophy (DMD).
- Conditions
- Muscular Dystrophies, Muscular Dystrophy, Duchenne, Muscular Disorders, Atrophic, Muscular Diseases
- Trial name
- HOPE-2 (NCT03406780)
- Testing
- CAP-1002
- Where
- 9 sites in United States
- Volunteers
- 20 people
- Sponsor
- Capricor Inc.
Pulmonary Arterial Hypertension Related to Eisenmenger Physiology
Effects of Tracleer (Bosentan) on Pulmonary Arterial Hypertension Related to Eisenmenger Physiology
This study evaluates the effects of bosentan on oxygen saturation, hemodynamics and exercise capacity in patients with pulmonary arterial hypertension related to Eisenmenger physiology.
- Trial name
- NCT00317486
- Testing
- bosentan
- Volunteers
- 54 people
- Sponsor
- Actelion
Atelectasis, Pulmonary Infection
Bi-PAP vs Sham Bi-PAP on Pulmonary Function in Morbidly Obese Patients After Bariatric Surgery
The effect of biphasic positive airway pressure (Bi-PAP) at individualized pressures on the postoperative pulmonary recovery of morbidly obese patients (MOP) undergoing open bariatric surgery (OBS) and possible placebo…
- Conditions
- Atelectasis, Pulmonary Infection, Chronic Obstructive Pulmonary Disease (COPD), Pulmonary Disease
- Trial name
- NCT03438383
- Testing
- Bi-PAP
- Volunteers
- 48 people
- Sponsor
- Evangelismos Hospital
COPD, Interstitial Lung Disease
Autologous Stem Cell Treatment for Chronic Lung Disease Study
The purpose of the Lung Institute is to collect and isolate a patient's own cells and platelet rich plasma (PRP) and deliver the product back to the patient the same day.
- Trial name
- NCT03044431
- Testing
- Cell therapy
- Where
- United States
- Volunteers
- 207 people
- Sponsor
- Lung Institute
Bronchopulmonary Dysplasia, Necrotizing Enterocolitis
Effects of Delayed Cord Clamping in Very Low Birth Weight Infants
The purpose of this study was to see if a brief delay in cord clamping for 30 to 45 seconds would result in higher hematocrit levels, fewer transfusions, healthier lungs, and better motor function at 40 wks and 7 months of age.
- Conditions
- Bronchopulmonary Dysplasia, Necrotizing Enterocolitis, Intraventricular Hemorrhage, Late Onset Neonatal Sepsis
- Trial name
- NCT00840983
- Testing
- delayed cord clamping
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Rhode Island
Cystic Fibrosis
Modeling of Chest Physiotherapy Using Impedance Measurements (PHYSIOMOD)
"The usefulness of respiratory physiotherapy and its execution modalities remains highly debated even though reviews of the literature show that respiratory physiotherapy is able to improve the drainage of bronchial secretions…
- Trial name
- PHYSIOMOD (NCT04094441)
- Testing
- chest physiotherapy
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Copd, COVID-19
Physiology and Structure of the Small Airways in Patients With Chronic Airflow Obstruction or COVID-19
The purpose of this research project is to study small airways physiological function in patients with chronic obstructive lung disease or COVID-19 and explore the relationship with in-vivo microanatomical small airway structure…
- Conditions
- Copd, COVID-19, Asthma, Small Airways Disease
- Trial name
- PASSPORT (NCT04716023)
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- Imperial College London
Vitamin D3 Deficiency, Prematurity
Vitamin D and Health Outcomes in Preterm Born Population
Improved survival of very preterm newborn population during the last decades has challenged us neonatologists to study and improve nutritional practices including vitamin D (VitD) supplementation.
- Conditions
- Vitamin D3 Deficiency, Prematurity, Lung Diseases, Heart Rate Variability
- Trial name
- ViDePrePop (NCT04342078)
- Testing
- Vitamin D
- Where
- Finland
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Oulu