Clinical trials: Quantitative Sensory Testing
Intellectual Disability
Characterization of Nociception Phenotype in Individuals With Intellectual Disability
Background: People with intellectual disability (ID) often have physical disabilities as well. These physical problems can affect their bones, muscles, nerves, and gastrointestinal tracts. All of these issues can also cause pain.
- Trial name
- NCT05473429
- Testing
- TSA2 Thermosensory Stimulator
- Where
- United States
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Chronic Pancreatitis, Chronic Pain
Pancreatic Quantitative Sensory Testing (P-QST)
Quantitative Sensory Testing (QST) is a novel investigative technique used in other pain conditions to evaluate patterns of chronic pain, and in this study will be used to elucidate pain patterns in patients with Chronic…
- Conditions
- Chronic Pancreatitis, Chronic Pain, Acute Recurrent Pancreatitis
- Trial name
- NCT06996535
- Testing
- Quantitative Sensory Test 1, Quantitative Sensory Test 2, Quantitative Sensory Test 3
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Sickle Cell Disease, Pain
Integrative Medicine in Pain Management in Sickle Cell Disease
The proposed research is to determine the clinical efficacy and neurobiological mechanisms of acupuncture analgesia in patients with sickle cell disease.
- Conditions
- Sickle Cell Disease, Pain, Acupuncture, Quantitative Sensory Testing
- Trial name
- NCT05045820
- Testing
- needling acupuncture, laser acupuncture
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Indiana University
Fabry's Disease
Analysis of the Nervous System in Patients With Fabry's Disease
Fabry's disease a genetic disorder (X-linked recessive) due to the absence of the enzyme ceramidetrihexosidase. The disease is characterized by abnormal collections of glycolipids in cells (histiocytes) within blood vessel walls…
- Trial name
- NCT00001491
- Where
- United States
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Chronic Pain, Child
Exercise as Medicine for Pediatric Chronic Pain
Youth with chronic pain struggle to go to school, play sports, or spend time with friends and family due to pain. Medications are often ineffective, and aerobic exercise may improve both pain sensitivity and participation in…
- Conditions
- Chronic Pain, Child, Adolescent
- Trial name
- NCT07182006
- Testing
- Aerobic Exercise
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Neuropathic Pain, Sickle Cell Disease
Sickle Cell Pain: Intervention With Capsaicin Exposure
This study evaluates the safety and feasibility of using high dose topical capsaicin patches for the treatment of neuropathic pain in pediatric patients with sickle cell disease, as well as the feasibility of using a number of…
- Trial name
- SPICE (NCT03899246)
- Testing
- Eight Percent Topical Capsaicin
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital of Michigan
Sickle Cell Disease, Pain
Integrative Medicine in Pain Management in Sickle Cell Disease, 2.0
The proposed research is to determine the clinical efficacy and neurobiological mechanisms of acupuncture analgesia in patients with sickle cell disease.
- Conditions
- Sickle Cell Disease, Pain, Acupuncture, Quantitative Sensory Testing
- Trial name
- NCT06725550
- Testing
- needling acupuncture, laser acupuncture
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Exercise Training, Breast Cancer
Moderate-Intensity Exercise and Pain Sensitization in Breast Cancer Survivors: A Case-Based Study
The aim of this study was to evaluate the feasibility, safety, and acceptability of a supervised, combined moderate-intensity aerobic and resistance training program designed to reduce pain sensitization in BCS with persistent…
- Conditions
- Exercise Training, Breast Cancer, Pain Management
- Trial name
- NCT07128030
- Testing
- Exercise
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Universidad Rey Juan Carlos
Autism Spectrum Disorder (ASD), Pain Perception
Quantitative Sensory Testing to Study Pain Perception in Autism
This study aims at assess sensory perception, and pain perception, in neurodivergent children and adolescent in the autism spectrum.
- Trial name
- PPiA (NCT06659731)
- Testing
- Quantitative Sensory testing (QST), EEG
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Facial Pain
MRI & QST Analysis in Trigeminal Neuralgia and Persistent Idiopathic Facial Pain
Patients with a definite diagnosis of classical TGN and PIFP will undergo a structured clinical questionnaire and a trigeminal sensory profile using the quantitative sensory testing.
- Trial name
- NCT05147454
- Testing
- Quantitative Sensory Testing
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Walton Centre NHS Foundation Trust
Complex Regional Pain Syndromes
Markers of Trajectory in Pediatric CRPS
Complex Regional Pain Syndrome (CRPS) is a severe and complex chronic pain condition in children. Many psychosocial factors impact its development and recovery.
- Trial name
- NCT03838107
- Testing
- observation and measure of trajectory of recovery in CRPS
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pain
Screening Protocol
This study is a screening evaluation for volunteers who are interested in participating in National Center for Complementary and Integrative Health (NCCIH) research studies about pain and related processes, such as emotion, mood…
- Trial name
- NCT07712874
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Chronic Pain
Clinical Assessment of Pain Processes in Pediatric Patients With Chronic Musculoskeletal Pain
Musculoskeletal (MSK) pain is one of the most common types of pain among children and adolescents. Recurring episodes of MSK pain during childhood does not only impact physical and psychological aspects of daily life but may…
- Trial name
- MSK (NCT04308044)
- Where
- Canada
- Volunteers
- 518 people, healthy volunteers welcome
- Sponsor
- Shriners Hospitals for Children
Hip Osteoarthritis, Total Hip Arthroplasty
Clinical Phenotypes in Persons With Hip Osteoarthritis and Prognostic Factors for Outcome After Total Hip Arthroplasty
This prospective longitudinal cohort study aims (1) to identify clinical phenotypes in persons with hip osteoarthritis and after total hip arthroplasty, and (2) to identify prognostic factors for outcomes after total hip…
- Trial name
- HIPPROCLIPS (NCT05265858)
- Testing
- Total Hip Arthroplasty
- Where
- 2 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- Hasselt University
Sickle Cell Disease, Chronic Pain
Predictors of Pain in Sickle Cell Disease
Sickle cell disease is a painful inherited disorder that affects approximately 100,000 people in the United States, and more than half of these individuals develop chronic or persistent pain that is often severe and disabling.
- Trial name
- NCT06139510
- Testing
- Quantitative sensory testing
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Duke University
ADPKD, Pain
Somatosensory Phenotyping of ADPKD
Over 60% of patients with ADPKD suffer from pain, mostly in the abdomen, flank and back, often leading to the diagnosis. It is challenging to manage and cure the pain; approximately 39% of patients are not satisfied with their…
- Trial name
- NCT06970028
- Testing
- Quantitative Sensory Testing, Questionnaires regarding pain and quality of life
- Where
- Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Sickle Cell Disease, Neuropathic Pain
Neuropathic Pain in Jamaicans With Sickle Cell Disease
Pain is the most common component of the morbidity seen in sickle cell disease (SCD), and may be acute or chronic. It is most commonly acute and a result of the hallmark vaso-occlusive episodes of the disease.
- Trial name
- NCT04015401
- Where
- Jamaica
- Volunteers
- 257 people
- Sponsor
- The University of The West Indies
SCD With Severe Phenotype (HbSS, HbSβ0 Thalassemia, HbSOARab)
QST-Pupillometry in Sickle Cell Disease Patients
There has been little progress for effective treatment of pain in sickle cell disease (SCD) patients. Many organizations have recognized that understanding the causes and reducing the burden of pain in SCD is critical in order to…
- Trial name
- QST (NCT02242058)
- Testing
- Quantitative sensory testing
- Where
- 2 sites in United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Julia Finkel
Adolescent Idiopathic Scoliosis, Cerebral Palsy
Pain Assessment in Children Undergoing Spine Surgery
Musculoskeletal (MSK) pain is one of the most common types of pain among children and adolescents. Recurring episodes of MSK pain conditions have a major impact on the daily lives.
- Trial name
- NCT04244760
- Testing
- Pain assessment for verbal patients, Pain assessment for non-verbal patients
- Where
- Canada
- Volunteers
- 240 people
- Sponsor
- Catherine Ferland