Clinical trials: Radiation Tolerance
Radiation Tolerance
Radiation Dosimetry in Teeth
Irradiation of any tissue creates changes in that tissue. Ionizing radiation imparts charges to the tissue as it interacts with tissue components, changing the tissue structure.
- Trial name
- NCT00178347
- Testing
- Exposure to irradiation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Rochester
Conscious Sedation Failure During Procedure
Ketamine Tolerance in Children After Repeated Administrations During Radiotherapy Sessions
Ketamine provides a safety zone for sedated but spontaneously ventilated children especially in remote conditions such as radiotherapy units where sedation is an essential practice for children to keep calm and motionless In this…
- Trial name
- NCT02512055
- Testing
- Ketamine
- Volunteers
- 33 people
- Sponsor
- Baskent University
Cancer
Genetic Susceptibility and Risk of Second Cancers in Patients Who Have Undergone Stem Cell Transplant for Cancer
RATIONALE: Identifying genes that increase a person's susceptibility to second cancers may help the study of cancer treatment. PURPOSE: This study is looking at genetic susceptibility and risk of second cancers in patients who…
- Trial name
- NCT00949052
- Testing
- DNA analysis, polymorphism analysis, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Cancer-related Problem/Condition
Description of Individual Radiosensitivity With Molecular Biomarkers in a Pediatric Oncology Population
This study aims to explore prospectively the distribution of individual radiosensitivity in the pediatric population and to determine the predictive power of individual radiosensitivity biomarkers from an immunofluorescence…
- Trial name
- ARPEGE BioM (NCT02827552)
- Testing
- skin biopsy
- Where
- 11 sites in France
- Volunteers
- 40 people
- Sponsor
- Institut de Cancérologie de Lorraine
Radiosensitivity, Pediatric Cancer
Integrative Molecular Analysis of Individual Radiosensitivity in Pediatric Oncology
Analysis of the individual radiosensitivity in pediatric oncology
- Conditions
- Radiosensitivity, Pediatric Cancer, Radiation Toxicity
- Trial name
- FOCUSO (NCT06033183)
- Testing
- Blood sample
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- Neolys
Cancer
Unusual Toxicity Induced by Radiotherapy
In order to evaluate the physiopathological knowledge of the different pathological manifestations associated with individual radiosensitivity, it seems essential to carry out this pilot study.
- Trial name
- CRYOTOX (NCT03980977)
- Testing
- skin biopsy, tumor biopsy, blood sample
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Institut de Cancérologie de Lorraine
Sickle Cell Disease
Phase I/II Pilot Study of Mixed Chimerism to Treat Hemoglobinopathies
The goal of this research study is to establish chimerism and avoid graft-versus-host disease in patients with Hemoglobinopathies to halt disease progression.
- Trial name
- NCT00777231
- Testing
- Enriched Hematopoetic Stem Cell Infusion
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- Talaris Therapeutics Inc.
Prostate Cancer
Blood Test to Measure DNA Damage in Blood
To check the radiosensitivity level in individual patients based on their DNA damage level.
- Trial name
- NCT00523471
- Testing
- Blood test
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- AHS Cancer Control Alberta
Genotoxicity, Cytotoxicity
Assessment of Cytotoxicity, Genotoxicity
Goal: The goal of this observational study is to evaluate the genotoxic and cytotoxic effects of OPG and CBCT on exfoliated buccal mucosal cells Main question: Does CBCT cause greater genotoxic and cytotoxic effects on buccal…
- Conditions
- Genotoxicity, Cytotoxicity, Ionizing Radiation Exposure, Dental X-Ray Exposure
- Trial name
- NCT07330401
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yaxin Wang