Clinical trials: Randomised Controlled Trial
Video Game Addiction, Gaming Disorder
Community-Based Intervention to Reduce Problematic Video Game Use in First-Year Secondary School Students: A Cluster Randomised Controlled Trial
This cluster randomised controlled trial will evaluate whether a community-based, multicomponent intervention can reduce problematic video game use and gaming disorder among first-year secondary school students in Pontevedra…
- Trial name
- AQJ (NCT07357792)
- Testing
- Community-Based Component, Adolescent Mindfulness Component, Adult Mindfulness Component
- Where
- Spain
- Volunteers
- 492 people, healthy volunteers welcome
- Sponsor
- Fundacin Biomedica Galicia Sur
Adolescent Idiopathic Scoliosis, Patient Engagement
Designing Multimedia Patient Education for Adolescent Idiopathic Scoliosis
The goal of this triple-masked three-armed feasibility randomised controlled trial is to compare patient education materials for participants with adolescent idiopathic scoliosis.
- Trial name
- PEMAIS (NCT06090344)
- Testing
- Traditional video format, Evidence-informed video format
- Where
- Ireland
- Volunteers
- 46 people
- Sponsor
- University College Dublin
Attention Deficit Hyperactivity Disorder
A Controlled Study of Parent Training in the Treatment of ADHD in Young Children
The purpose of this study is to investigate the effectiveness of parent training in the treatment of ADHD in young children (ages 3-7) referred to Danish child mental health services.
- Trial name
- D'SNAPP (NCT01684644)
- Testing
- New Forest Parenting Programme, Treatment as usual
- Where
- Denmark
- Volunteers
- 164 people
- Sponsor
- University of Aarhus
Laparoscopic Cholecystectomy, Choledocholithiasis
Early vs Late Laparoscopic Cholecystectomy After Common Bile Duct Stones Clearance Through Ercp.
There is controversy about timing of cholecystectomy after the common bile duct is cleared of stones. our study aims to compare the results of early vs late cholecystectomy.
- Conditions
- Laparoscopic Cholecystectomy, Choledocholithiasis, ERCP, Bile Duct Injury
- Trial name
- NCT07130864
- Testing
- Early cholecystectomy, Late cholecystectomy
- Where
- Pakistan
- Volunteers
- 136 people
- Sponsor
- Khyber Teaching Hospital
Tuberculosis, Pulmonary, Quality of Health Care
The Effectiveness of Health Facility-based and Community-based Care for Tuberculosis
The purpose of the study is whether the provision of tuberculosis care using volunteer community health workers or self-administered treatment for 7 months is equally effective with the existing 8 months of TB care in public…
- Conditions
- Tuberculosis, Pulmonary, Quality of Health Care, Community Health Care, Volunteer Health Workers
- Trial name
- NCT00939419
- Testing
- Health workers TB care group, Community health workers TB care group, Self-administered treatment group
- Where
- Ethiopia
- Volunteers
- 924 people
- Sponsor
- University of Leeds
Malaria
Evaluating ATSBs for Malaria Reduction in Kenya
The effectiveness of long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) in western Kenya are threatened by insecticide resistance and vector behaviour changes toward early evening and outdoor biting malaria…
- Trial name
- NCT05219565
- Testing
- Attractive Targeted Sugar Bait (ATSB)
- Where
- 9 sites in Kenya
- Volunteers
- 2,962 people, healthy volunteers welcome
- Sponsor
- Liverpool School of Tropical Medicine
Human Immunodeficiency Virus
Nucleosides And Darunavir/Dolutegravir In Africa
This trial evaluates options for second-line antiretroviral therapy in patients failing on a non-nucleoside reverse transcriptase inhibitor (NNRTI) and tenofovir (TDF)-based first-line regimen in the setting of the public health…
- Trial name
- NADIA (NCT03988452)
- Testing
- Darunavir, Ritonavir, Dolutegravir
- Where
- Uganda
- Volunteers
- 465 people
- Sponsor
- Makerere University
Asthma Childhood, Respiratory Muscle Training
Effects of Expiratory Muscle Training in Children With Asthma: A Randomised Controlled Trial
The goal of this randomized clinical trial is to evaluate the effectiveness of expiratory muscle training (EMT) as an adjunct to conventional chest physiotherapy in children with asthma.
- Trial name
- NCT07169071
- Testing
- Home-based chest physiotherapy program, Expiratory Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Atlas University
Child Obesity
Efficacy of Nuts in Obese Children.
Obesity is a problem of ever-growing importance, especially in industrialized countries, both in adults and in the pediatric population.
- Trial name
- NCT03870984
- Testing
- wNUTS, low-caloric diet plus nuts, w/oNUTS, low-caloric diet without nuts
- Where
- Italy
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Infant, Very Low Birth Weight
High Protein and High Energy Intakes and Physical Activity on Growth of Extremely Low Birth Weight Infants
The aim of this study is to evaluate the effect of increasing amino acid and energy intake during parenteral and enteral nutrition with and without the stimulation of the infant's physical activity, on growth of extremely low…
- Trial name
- NCT03374033
- Testing
- NUTR +, STIMUL +
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Università Politecnica delle Marche
Obesity, Overweight
Early Stockholm Obesity Prevention Program
To study whether a targeted intervention can prevent the development of overweight and obesity among pre-school children in families with either one obese or two overweight parents.
- Trial name
- EarlySTOPP (NCT01198847)
- Testing
- Dietary, physical activity and sleeping
- Where
- Sweden
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
BPD - Bronchopulmonary Dysplasia, NEC - Necrotizing Enterocolitis
Targeted vs Standard Fortification of Breast Milk
BACKGROUND: Human milk (HM) is recommended for all very low birth infants (VLBW)). Breast-milk is highly variable in nutrient content, failing to meet the nutritional demands of VLBW.
- Conditions
- BPD - Bronchopulmonary Dysplasia, NEC - Necrotizing Enterocolitis, Weight Gain, VLBW - Very Low Birth Weight Infant
- Trial name
- NCT03775785
- Testing
- Tailored enteral nutrition
- Where
- 2 sites in Poland
- Volunteers
- 200 people
- Sponsor
- Princess Anna Mazowiecka Hospital, Warsaw, Poland
Hip Fractures
Cemented Hemiarthroplasty Versus Uncemented Furlong Hemiarthroplasty
In England each year over 9,000 people fracture their hip. Most of these are elderly females with the fracture occurring after a fall.
- Trial name
- NCT02998034
- Testing
- Uncemented Furlong Hemiarthroplasty, Cemented tapered stem hemiarthroplasty
- Where
- United Kingdom
- Volunteers
- 400 people
- Sponsor
- Peterborough and Stamford Hospitals NHS Foundation Trust
Health Knowledge, Attitudes, Practice, Drinking Behaviour
Promoting Alcohol-related Attitudinal and Behavioural Change Amongst Adolescents Through Internet Intervention
Objectives The aims of this study are to test the effectiveness of an online quiz competition in changing adolescents' alcohol-related attitudes and behaviour and to explore the fe¬asibility of using Internet viral marketing to…
- Trial name
- NCT02450344
- Testing
- Interactive health promotion, Passive health promotion
- Volunteers
- 7,933 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Seizures
Doxycycline for the Treatment of Nodding Syndrome
Nodding syndrome (NS) is a devastating neurologic disorder affecting thousands of children in Africa. A number of toxic, nutritional, infectious, para-infectious and environmental causes have been studied but the only consistent…
- Trial name
- NCT02850913
- Testing
- Doxycycline
- Where
- Uganda
- Volunteers
- 230 people
- Sponsor
- Makerere University
Failed Induction (of Labor) by Oxytocin
Continuous Oxytocin Infusion Versus Pulsatile Intravenous Oxytocin for Augmentation of First Stage of Labor
Comparing continuous intravenous oxytocin infusion with pulsatile administration of intravenous oxytocin for augmentation of the first stage of labor.
- Trial name
- NCT02723461
- Testing
- Pulsatile Oxytocin, Continuous Oxytocin
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Atopy, Asthma
Vitamin A Supplementation at Birth and Atopy in Childhood
INTRODUCTION Eight trials studying the effect of providing neonatal vitamin A supplementation (NVAS) have been reported, and another four are underway to test whether NVAS should become WHO policy.
- Conditions
- Atopy, Asthma, Eczema, Food Allergy
- Trial name
- NCT01779180
- Where
- Guinea-Bissau
- Volunteers
- 2,000 people
- Sponsor
- Bandim Health Project
Acute Respiratory Distress Syndrome
Efficacy Study of Dexamethasone to Treat the Acute Respiratory Distress Syndrome
BACKGROUND: Currently, there is no proven pharmacologic treatment for patients with the acute respiratory distress syndrome (ARDS).
- Trial name
- DEXA-ARDS (NCT01731795)
- Testing
- Dexamethasone
- Where
- 2 sites in Spain
- Volunteers
- 277 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Anxiety Disorders
Internet-delivered Cognitive Behavior Therapy (CBT) for Children Age 8-12 Years With Anxiety Disorders
The purpose of this study is to investigate whether a 10 week Internet-delivered CBT is a feasible approach to treat children (age 8-12 years) with anxiety disorder (social phobia, panic disorder, specific phobia, generalized…
- Trial name
- NCT01533402
- Testing
- therapist support, Internet-delivered CBT
- Where
- Sweden
- Volunteers
- 128 people
- Sponsor
- Karolinska Institutet
Healthy
Investigating the Acute Effects of Blueberry (Poly)Phenols on Vascular Function and Cognition in Healthy Individuals.
This study aims to determine the effect of blueberry (poly)phenol vs placebo on vascular function and cognitive performance with an insight into cerebral blood flow velocity changes, across all ages of the general healthy…
- Trial name
- BluLife (NCT03592966)
- Testing
- Wild Blueberry Powder
- Where
- United Kingdom
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- King's College London
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