Clinical trials: Randomised Controlled Trial
Pain
Non-Nutritive Sucking and Swaddling for Pain Relief in Term Neonates: Randomised Controlled Trial
Non pharmacological approaches are important in pain control in neonates, specially in term healthy neonates. Non-nutritive sucking and swaddling are considered effective strategies for pain control in these population, but the…
- Trial name
- NCT00547807
- Testing
- Non-nutritive sucking, Swaddling
- Where
- Brazil
- Volunteers
- 34 people
- Sponsor
- Sociedade Hospital Samaritano
Peritoneal Inflammation
Humidification in Laparoscopic Colonic Surgery
Laparoscopic surgery allows surgeons to remove bowel via small incisions. To allow insertion of a camera and instruments, cold and dry gas is blown into the abdominal cavity.
- Trial name
- NCT00642005
- Testing
- Fisher and Paykel Humidifier (MR860), Standard insufflation
- Where
- 3 sites in New Zealand
- Volunteers
- 82 people
- Sponsor
- University of Auckland, New Zealand
HPV Infection, HPV-Related Carcinoma
A Phase I Clinical Trial to Evaluate the Safety of 15-valent HPV Vaccine in Healthy Chinese People Aged 18-45 Years
To evaluate the safety and tolerability of 15-valent HPV vaccine in 9-45year-old participants.
- Conditions
- HPV Infection, HPV-Related Carcinoma, Genital Wart, HPV-Related Intraepithelial Neoplasia
- Trial name
- NCT06454175
- Testing
- 15-valent recombinant human papillomavirus vaccine (Hansenulapolymorpha)
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Shanghai Bovax Biotechnology Co., Ltd.
Infectious Disease, Infections
L-citrulline to Improve Adverse Outcomes in Admitted Children (EChiLiBRiST, Clinical Trial 2, Inpatients)
In low and middle-income countries, children admitted to hospital are not similarly ill, and do not all have a comparable prognosis.
- Conditions
- Infectious Disease, Infections, Child, Only
- Trial name
- NCT06426147
- Testing
- L-citrulline
- Where
- 2 sites in Ethiopia, Mozambique
- Volunteers
- 2,200 people
- Sponsor
- Barcelona Institute for Global Health
Emotions
An In-situ, Child-led Intervention To Promote Emotion Regulation Competence in Middle Childhood: Protocol For an Exploratory Randomised Control Trial
The aim of this study is to examine, for the first time, the efficacy of a new intervention model for child-led emotion regulation -Purrble- that could be deployed across prevention and treatment contexts.
- Trial name
- NCT04810455
- Testing
- Purrble, Active control toy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- King's College London
Human Immunodeficiency Virus
Nucleosides And Darunavir/Dolutegravir In Africa
This trial evaluates options for second-line antiretroviral therapy in patients failing on a non-nucleoside reverse transcriptase inhibitor (NNRTI) and tenofovir (TDF)-based first-line regimen in the setting of the public health…
- Trial name
- NADIA (NCT03988452)
- Testing
- Darunavir, Ritonavir, Dolutegravir
- Where
- Uganda
- Volunteers
- 465 people
- Sponsor
- Makerere University
Soft Tissue Injuries
Cost-effectiveness of Two Painkillers for Treating Pain After Limb Injuries
Background: Paracetamol and non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen are commonly used oral analgesics in emergency departments (ED) not only in Hong Kong but throughout the world.
- Trial name
- NCT00528658
- Testing
- Paracetamol, Ibuprofen
- Where
- Hong Kong
- Volunteers
- 782 people
- Sponsor
- Chinese University of Hong Kong
Growth; Stunting, Nutritional, Child Development
SPRING Cluster Randomised Controlled Trial
A large number of children in developing countries lack access to known effective interventions. Almost 9 million die each year before reaching their fifth birthday, and over 200 million children who survive fail to achieve their…
- Conditions
- Growth; Stunting, Nutritional, Child Development, Depression, Postpartum, Death
- Trial name
- SPRING (NCT02059863)
- Testing
- SPRING
- Where
- 2 sites in India, Pakistan
- Volunteers
- 12,000 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Renal Failure
Effects of Dexmedetomidine on Postoperative Renal Function Recovery After Kidney Transplantation in Adult Patients
Postoperative renal function recovery is very important to value the operation quality after kidney transplantation. Dexmedetomidine is a selective alpha-2 agonist,enhances urine flow rate and perioperative renal function.
- Trial name
- NCT02874378
- Testing
- Dexmedetomidine, 0.9%NaCl solution
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Mental Health Services
DAWBA as a Rapid Online Assessment Tool
The European Union is funding this randomised trial in Scotland as part of the larger eCAP project (http://www.interreg-npa.eu/projects/funded-projects/project/139/).
- Trial name
- eCAP:DAWBA (NCT03120338)
- Testing
- The Development and Wellbeing Assessment
- Where
- United Kingdom
- Volunteers
- 71 people
- Sponsor
- University of Aberdeen
Behavior Problem, Parenting
Internet-based Parent Training for Parents of Children With Externalising Behavior Problems
The study aims to evaluate the efficacy of a 5-week, therapist-guided, internet-delivered parent management training program (BIP SAMBA) targeting children aged 5 - 11 years with externalising behavior problems.
- Trial name
- BIP-SAMBA (NCT04670185)
- Testing
- BIP SAMBA
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet
Anxiety Acute, Anxiety Fear
Paediatric Peri-operative Anxiety: Does the Little Journey App Help?
To evaluate the clinical effectiveness of a virtual reality psychological preparation app at reducing peri-operative anxiety and its associated sequelae in children aged 3-12 years old undergoing ambulatory surgery compared to…
- Conditions
- Anxiety Acute, Anxiety Fear, Peri-operative, Psychological Distress
- Trial name
- NCT03797716
- Testing
- Little Journey app
- Where
- 17 sites in United Kingdom
- Volunteers
- 596 people, healthy volunteers welcome
- Sponsor
- University College, London
Body Dysmorphic Disorder
Cognitive Behaviour Therapy (CBT) for Body Dysmorphic Disorder (BDD)
The aim of the research is to determine if Cognitive Behaviour Therapy (CBT) specific for BDD is more effective than a credible non-specific form of CBT for treating BDD and its delusional variant in adults aged 17 or over.
- Trial name
- NCT00871143
- Testing
- CBT specific for BDD, Non specific CBT
- Where
- United Kingdom
- Volunteers
- 46 people
- Sponsor
- Institute of Psychiatry, London
Autism Spectrum Disorder, Parenting Stress
Feasibility and Acceptability of Laughter Yoga in Children With Autism Spectrum Disorder and Their Parents
This is a pilot randomised controlled trial to explore the acceptability and feasibility of laughter yoga about anxiety and depression reduction in children with ASD and parenting stress reduction for their parents.
- Conditions
- Autism Spectrum Disorder, Parenting Stress, Depression, Anxiety
- Trial name
- NCT06326255
- Testing
- laughter yoga
- Where
- Hong Kong
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- LAM Chung Yan Hemio
Local Anaesthetic Drug Adverse Reaction
Computer - Controlled Intraligamentary Local Anaesthesia In Extraction of Primary Molars
Background: Exodontia poses a psychological threat for children, increasing the need for profound local anesthesia to assure painless extraction and maintain child cooperation on the dental chair.
- Trial name
- NCT04739735
- Testing
- Dental Local Anaesthesia
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Hepatitis C, Chronic, Opioid Dependence, on Agonist Therapy
Integrated Treatment of Hepatitis C Virus Infection
INTRO-HCV is a multicentre randomised controlled clinical trial that will compare the efficacy of integrated treatment of chronic hepatitis C virus infection (HCV) within medically assisted rehabilitation (MAR) clinics providing…
- Trial name
- INTRO-HCV (NCT03155906)
- Testing
- Health care delivery
- Where
- 2 sites in Norway
- Volunteers
- 298 people
- Sponsor
- Haukeland University Hospital
Adult
Communicating Evidence From Systematic Reviews to the Public
The purpose of this randomised controlled trial is to compare a new standardised summary format for presentation of synthesised evidence from systematic reviews for the public (a new plain language summary format) to the current…
- Trial name
- PLSRCT (NCT01939925)
- Testing
- New plain language summary format, Current plain language summary format
- Where
- 5 sites in Argentina, Canada and 3 more
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Norwegian Knowledge Centre for the Health Services
Anxiety
Feasibility Study of a Music and Social Support Intervention for Postnatal Mothers/Infants
This research study aims to assess the feasibility of conducting a full scale trial of Mamas in Harmony, a group music and social support class delivered by a professional musician for mothers and their babies.
- Trial name
- NCT05930990
- Testing
- Mamas in Harmony
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Mental Disorder, Depressive Symptoms
Module-Based Psychological (MBP) for Community Youths
This waitlist, randomised controlled trial (RCT) aims to examine the effectiveness of the Module-Based Psychological (MBP) intervention in reducing mental distress for youths aged 12-30 years in Hong Kong.
- Conditions
- Mental Disorder, Depressive Symptoms, Anxiety Symptoms
- Trial name
- MBP_RCT (NCT06005961)
- Testing
- Module-Based Psychological (MBP) Intervention
- Where
- Hong Kong
- Volunteers
- 400 people
- Sponsor
- The University of Hong Kong
Acute Gastroenteritis
Efficacy of Lactose-free Milk in Treating Acute Gastroenteritis in Infants
The purpose of this study is to determine whether lactose-free milk will change diarrhea duration and severity in formula-fed infants with acute gastroenteritis presenting to pediatric wards.
- Trial name
- NCT05634603
- Testing
- Lactose-free milk formula (Frisolac LF ®)
- Where
- Vietnam
- Volunteers
- 66 people
- Sponsor
- The Women and Children Hospital of An Giang
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.