Clinical trials: Randomised Controlled Trial
Labor Stage, Second, Labor and Delivery
Visual Biofeedback Through Transperineal Ultrasound During the Expulsive Phase of Labour to Improve Maternal Childbirth Satisfaction
Childbirth is generally regarded as a positive life-changing experience. Up to 44% of women may however experience this as a traumatic event, with 3% suffering from post-traumatic stress disorder after childbirth.
- Conditions
- Labor Stage, Second, Labor and Delivery, Satisfaction With Care, Childbirth
- Trial name
- RCT:VB-TPU (NCT06847308)
- Testing
- visual biofeedback through trans-perineal ultrasound
- Where
- Belgium
- Volunteers
- 488 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cystic Fibrosis
Crossover Trial Determining the Efficacy of Dry Powder Mannitol to Improve Lung Function in Subjects Aged 6-17 Years
It is hypothesised that inhaled mannitol 400 mg b.d. will lead to a significant improvement in the absolute change in percentage of predicted FEV1 from baseline following eight-weeks of trial treatment compared to treatment with…
- Trial name
- NCT01883531
- Testing
- Inhaled Mannitol
- Where
- United Kingdom
- Volunteers
- 95 people
- Sponsor
- Syntara
Skin Condition, Cleft Lip and Palate
Online Psychosocial Support for Young People With a Visible Difference: A Randomised Control Study
A visible difference can have a profound impact in a society with a massive emphasis on appearance and "looks". A vulnerable group is adolescents with a condition affecting their appearance as a result of injuries (burns…
- Conditions
- Skin Condition, Cleft Lip and Palate, Burns, Other Conditions Leading to a Visible Difference
- Trial name
- UNGFaceIT (NCT03165331)
- Testing
- Ung Face IT
- Where
- Norway
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Gastrointestinal Bleeding
Haemorrhage Alleviation With Tranexamic Acid- Intestinal System
Severe bleeding in the digestive system is a common symptom of many diseases. Each year, about 50,000 people end up in British hospitals because of this problem and about 5,000 of them die.
- Trial name
- HALT-IT (NCT01658124)
- Testing
- Tranexamic Acid
- Where
- United Kingdom
- Volunteers
- 12,009 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Education, Midwifery
Effects of Concurrent Irrelevant Visual Stimuli on Learning Outcomes in Midwifery Education
This randomized controlled trial was designed to evaluate the effects of concurrent instructionally irrelevant visual stimuli on learning-related outcomes among third-year midwifery students.
- Conditions
- Education, Midwifery, Midwifery Education
- Trial name
- NCT07904923
- Testing
- Split-Screen Educational Presentation With Irrelevant Visual Stimulus, Standard PowerPoint-Supported Education
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Fatma Şule Bilgiç
Acute Bronchiolitis
The SABRE Trial of Hypertonic Saline in Acute Bronchiolitis
Acute bronchiolitis is a common, distressing illness affecting children. A virus infects the lungs, and then the airways become blocked, leading to difficulties with breathing.
- Trial name
- SABRE (NCT01469845)
- Testing
- 3% hypertonic saline
- Where
- 9 sites in United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sheffield Children's NHS Foundation Trust
Attitudes Towards Tobacco Industry
A Brief Intervention Programme for TID
The brief RCT will be conducted in the form of a questionnaire survey, with two kinds of leaflets embedded in the same questionnaire.
- Trial name
- NCT03800966
- Testing
- Leaflet
- Where
- Hong Kong
- Volunteers
- 1,069 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Developmental Language Disorder and Language Impairment, Anxiety Disorders and Symptoms
Reducing Anxiety Problems Among Children Indicated to Have Developmental Language Disorder
This study aims to pilot a world-first intervention, a mental health intervention augmented for children indicated with developmental language disorder (DLD).
- Trial name
- RAP-iDLD (NCT05552365)
- Testing
- Adapted Cognitive Behavioural, Treatment as Usual
- Where
- Singapore
- Volunteers
- 9 people
- Sponsor
- Nanyang Technological University
Autism Spectrum Disorder, Parent
The Effect of Applied Group Training Given to Mothers With Children With Autism on Perceived Social Support, Depressive Symptoms and Self-compassion
Autism Spectrum Disorder (ASD), which can also be defined as a type of special need, is a congenital neurodevelopmental disorder whose symptoms are observed in early childhood.
- Trial name
- NCT06862804
- Testing
- practical group training
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Kastamonu University
Malaria, Anemia
Evaluation of a Comprehensive School Health Programme in Zambia
In Zambia, the health and well-being of children aged 5 to 14 has often been overlooked, leading to various health challenges affecting their development and education.
- Conditions
- Malaria, Anemia, Diarrhea
- Trial name
- NCT06560853
- Testing
- Comprehensive School Health Programme, Deworming and vitamin A supplementation delivery
- Where
- 6 sites in Zambia
- Volunteers
- 28,700 people, healthy volunteers welcome
- Sponsor
- London School of Economics and Political Science
Pain
Continuous Versus Interrupted Sutures for Repair of Episiotomy or Second Degree Tears: a Randomised Controlled Trial
The best technique for this repair would be that which requires least time in realisation, least consumption of material for the repair and that which produces less pain at short and long-term permitting the resumption of…
- Trial name
- NCT00777270
- Testing
- repair of episiotomy or second degree tears
- Where
- Spain
- Volunteers
- 445 people
- Sponsor
- Hospital Universitario Principe de Asturias
Pyelonephritis
Short-term Antibiotic Therapy for Pyelonephritis in Childhood
The purpose of this study is to evaluate the efficacy of oral ceftibuten for 7 days versus 10 days in acute pyelonephritis in children.
- Trial name
- STUTI (NCT00724256)
- Testing
- ceftibuten
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- IRCCS Burlo Garofolo
Epilepsy
An Exploratory RCT of a Psychosocial Group Intervention for Epilepsy
Children and young people with epilepsy are at increased risk of poorer outcomes related to emotional and psychological adjustment, peer relationship problems, lower academic attainment and mental health problems across the…
- Trial name
- PIE (NCT02349529)
- Testing
- Psychosocial Intervention Group, Waiting list control
- Volunteers
- 200 people
- Sponsor
- NHS Greater Glasgow and Clyde
Female Breast Cancer
Acupuncture for Joint Symptoms in Patients With Breast Cancer
Joint symptoms including stiffness, local pain and aches are common adverse reactions among breast cancer (BC) patients undergoing hormone treatments, while effective interventions for managing such symptoms have not been well…
- Trial name
- NCT03836872
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 64 people
- Sponsor
- The Hong Kong Polytechnic University
Peri-implantitis
Surgical and Non-surgical Treatment of Peri-implantitis
This study will compare surgical and non surgical treatments of peri-implantitis. Peri-implantitis is an inflammation around dental implants that can lead to the loss of the implant over time if no treatment is established.
- Trial name
- Perio-implants (NCT02241577)
- Testing
- Surgical treatment, Non-surgical treatment
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Federal University of Rio Grande do Sul
Dysmenorrhea, Heavy Menstrual Bleeding
Effectiveness of an mHealth Innovation on the Impact of Menstrual Complaints in Adolescents
The aim of this study is to improve menstrual health-related quality of life in adolescents by using a mobile menstrual health tracker.
- Conditions
- Dysmenorrhea, Heavy Menstrual Bleeding, Menstrual Cramps, Menstrual Bleeding, Heavy
- Trial name
- MGA (NCT07457957)
- Testing
- Menstrual Tracker and Education Application
- Where
- Netherlands
- Volunteers
- 874 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Pes Planus
Orthotics for Treatment of Symptomatic Flat Feet in Children
Update 13.12.2021 To mitigate the effects the COVID-19 pandemic, and due to difficulties in sites setting up the custom orthoses arm of the protocol an amendment was approved to change the design of the study from a 3 to a 2 arm…
- Trial name
- OSTRICH (NCT04104555)
- Testing
- Birthday card, Prefabricated orthoses, Signposting to multimedia
- Where
- 16 sites in United Kingdom
- Volunteers
- 134 people
- Sponsor
- University of York
Early Childhood Caries (ECC)
Aesthetic and Functional Evaluation of a Universal One-Shade Composite in Primary Maxillary Incisors
Use of tooth-coloured fillings is an essential part of Pediatric dentistry as most patients desire fillings which look like natural teeth.
- Trial name
- NCT07716033
- Testing
- Tokuyama Palfique Omnichroma composite restoration, 3M Filtek Z350 composite restoration
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Goa Dental College
Arthropathy of Hip
Study Comparing BoneMaster Hydroxyapatite Coating With Plasma-sprayed Hydroxyapatite Coating on Acetabular Cups
The randomised controlled trial will be carried out on patients that require a total hip replacement (THR) to reduce pain and restore their function.
- Trial name
- NCT00859976
- Testing
- BoneMaster coated acetabular shell., Plasma Coated Acetabular Shell
- Where
- United Kingdom
- Volunteers
- 167 people
- Sponsor
- Zimmer Biomet
Otitis Media
Long-term Antibiotics for Treatment and Prevention of Otitis Media in Aborignal Children
This clinical trial was conducted in a population where tympanic membrane perforation occurs in 60% infants in the first year of life.
- Trial name
- COMIT1 (NCT00539149)
- Testing
- Amoxycillin
- Where
- Australia
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Menzies School of Health Research
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