Clinical trials: Randomised Controlled Trial
Approximal Dental Caries (ICDAS 3-5) in Primary Molars of Children
A Randomized Clinical Trial Comparing Hall vs. Conventional Technique in Primary Molars.
This study aims to assess the comparative effectiveness of the Hall technique (HT) and the conventional technique (CT) for placing Stainless Steel Crowns (SSCs) in primary molars with approximal caries.
- Trial name
- NCT06350578
- Testing
- Hall Crown Technique, Conventional SSC Technique
- Where
- Qatar
- Volunteers
- 80 people
- Sponsor
- Primary Health Care Corporation, Qatar
Pyloric Stenosis
Open vs Laparoscopic Pyloromyotomy for Pyloric Stenosis
Comparison of open and laparoscopic pyloromyotomy
- Trial name
- NCT00144924
- Testing
- laparoscopy pyloromyotomy, open pyloromytomy
- Where
- United Kingdom
- Volunteers
- 180 people
- Sponsor
- Institute of Child Health
Foetal Growth Problem, Small for Gestational Age
Growth Hormone Treatment in Children Born Small for Gestational Age (SGA)
This study is conducted in Japan. The aim of this trial is to assess the efficacy and safety of somatropin in children born small for gestational age (SGA) in Japan.
- Trial name
- NCT00184717
- Testing
- somatropin
- Where
- Japan
- Volunteers
- 98 people
- Sponsor
- Novo Nordisk A/S
Visual Fatigue
The Effect of 3D Autostereoscopic Video-game Play on the Visual Fatigue in Children
This study aims to examine the specific effect that 3D game play has on the control of the eyes horizontal movements. It will examine the youngest group of consumers this technology is marketed to, 7 to 11-year-olds and no…
- Trial name
- NCT02407015
- Testing
- Nintendo 3DS gameplay
- Where
- United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
Pediatric Cancer
Nurse-led Transitional Care to Improve Symptom Management in Childhood Cancer Survivors
This study aims to evaluate the feasibility and preliminary effectiveness of a nurse-facilitated interdisciplinary transitional care programme, based on the Omaha system, for Chinese childhood cancer survivors (CCSs) and their…
- Trial name
- NCT07273682
- Testing
- Counseling based on Omaha system, Usual Care
- Volunteers
- 68 people
- Sponsor
- The Hong Kong Polytechnic University
Pelvic Organ Prolapse
PEssary Plus Physiotherapy for Pelvic Organ Prolapse (PEPPY)
1. To determine the feasibility of conducting a randomised controlled trial (RCT) of the effectiveness of a PFMT intervention in conjunction with vaginal pessary management versus vaginal pessary management alone for women with…
- Trial name
- PEPPY (NCT01136889)
- Testing
- PFMT
- Where
- 4 sites in United Kingdom
- Volunteers
- 16 people
- Sponsor
- Glasgow Caledonian University
HIV Infections
Reducing HIV in Adolescents
The purpose of this study is to assess the impact of a cash-incentivised prevention intervention on reducing HIV incidence rates in high-school learners in rural KwaZulu-Natal.
- Trial name
- RHIVA (NCT01187979)
- Testing
- Cash incentives, Life skills curriculum
- Where
- South Africa
- Volunteers
- 3,217 people, healthy volunteers welcome
- Sponsor
- Centre for the AIDS Programme of Research in South Africa
Infertility
Trial Comparing hCG Triggering Versus hCG Associated With GnRH Agonist
The purpose of this study is to see whether patients triggered with only human Chorion Gonadotropin (hCG) have higher number of Metaphase II oocytes (MII) and implantation rate than patients triggered with hCG combined with…
- Trial name
- NCT01607203
- Testing
- Decapeptyl Daily, pregnyl
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- AZ Jan Palfijn Gent
Proteinuric Kidney Diseases
PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney Disease
This study is open to adults with certain kidney conditions, including secondary focal segmental glomerulosclerosis (sFSGS), treatment-resistant primary minimal change disease (TR-pMCD), Alport Syndrome (AS), and…
- Trial name
- NCT07355296
- Testing
- BI 764198
- Where
- 154 sites in United States, Argentina and 30 more
- Volunteers
- 132 people
- Sponsor
- Boehringer Ingelheim
Diarrhea, Respiratory Tract Infections (RTI)
Impact Evaluation of Accelerating Climate-Resilient Water, Sanitation and Hygiene Services for Schools and Healthcare Facilities in Karamoja
Karamoja, in north-eastern Uganda, is among the most water-insecure regions in sub-Saharan Africa. Only 24 per cent of households can access the WHO-recommended 20 litres of water per person per day.
- Conditions
- Diarrhea, Respiratory Tract Infections (RTI), Menstrual Hygiene, Absenteeism
- Trial name
- NCT07823231
- Testing
- Climate-resilient school WASH infrastructure package, WASH and menstrual health capacity building and social and behaviour change package
- Where
- Uganda
- Volunteers
- 16,380 people, healthy volunteers welcome
- Sponsor
- Elijah Kipchumba
Difficulty Writing
Effectiveness of the Occupational Therapy Handwriting Intervention Guideline on Children
This study aims to evaluate the effectiveness of the Occupational Therapy Handwriting Interventions Guidelines (OTHIG) in enhancing handwriting performance among children.
- Trial name
- NCT05217394
- Testing
- OTHIG
- Where
- 4 sites in Malaysia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Allergic Rhinitis
Efficacy and Safety Trial of Pangramin SLIT HDM-mix in Subjects With House Dust Mite Induced Rhinitis
Primary aim is to evaluate the efficacy of specific immunotherapy with Pangramin SLIT HDM-mix compared to placebo in the treatment of House Dust Mite (HDM) induced rhinitis with or without asthma.
- Trial name
- NCT01603056
- Testing
- Pangramin SLIT HDM mix.
- Where
- China
- Volunteers
- 617 people
- Sponsor
- ALK-Abelló A/S
Asthma
Efficacy and Safety of 3 Doses of Tiotropium Compared to Placebo in Adolescents (12 to 17 Yrs) With Moderate Asthma
The primary objective of this trial is to evaluate the efficacy and safety of tiotropium 1.25 mcg (2 actuations of 0.625 mcg), tiotropium 2.5 mcg (2 actuations of 1.25 mcg) and tiotropium 5 mcg (2 actuations of 2.5 mcg) once…
- Trial name
- NCT01122680
- Testing
- Tiotropium bromide
- Where
- 19 sites in United States, Germany and 3 more
- Volunteers
- 105 people
- Sponsor
- Boehringer Ingelheim
Hematopoietic Cell Transplantation
Randomised Controlled Trial Comparing CD62L and CD45RA Depleted Donor Lymphocyte Infusion With T-cell Depleted Haploidentical Hematopoietic Stem Cell Transplantation
The goal of clinical trial is to compare the efficacy and safety of CD62L depleted donor lymphocyte infusion (DLI) with CD45RA depleted DLI in children who receive T-cell depleted haploidentical hematopoietic stem cell…
- Trial name
- NCT07867769
- Testing
- CD62L depleted DLI, CD45RA depleted DLI, Haploidentical HSCT
- Where
- Hong Kong
- Volunteers
- 46 people
- Sponsor
- Hong Kong Children's Hospital
Cystic Fibrosis
A 4-week Study to Test Different Doses of BI 1265162 in Adolescents and Adults With Cystic Fibrosis Using the Respimat® Inhaler - BALANCE - CF™1
The primary objective of this trial is to assess the efficacy, safety and pharmacokinetics of twice daily inhaled doses of BI 1265162 delivered by Respimat® inhaler versus placebo in adolescents and adult patients with cystic…
- Trial name
- NCT04059094
- Testing
- BI 1265162
- Where
- 26 sites in United States, Belgium and 6 more
- Volunteers
- 52 people
- Sponsor
- Boehringer Ingelheim
Osteoporosis, Liver Transplantation
The Effect of Zoledronic Acid on Bone Density in Liver Transplant Patients
Following liver transplantation, rapid bone loss occurs, particularly within the first 6 months post-transplant. This may be associated with fractures, most notable vertebral.
- Conditions
- Osteoporosis, Liver Transplantation, Fractures
- Trial name
- NCT00114556
- Testing
- zoledronic acid
- Where
- Australia
- Volunteers
- 100 people
- Sponsor
- Royal Prince Alfred Hospital, Sydney, Australia
Local Anesthesia
Effectiveness of Sodium Bicarbonate Buffered Anaesthetic Solution on Pain During Injection
This study will test the effectiveness of addition of Sodium Bicarbonate as a buffering agent to the anaesthetic solution on minimizing the pain of injection and increasing the onset time and potency of the anaesthetic solution…
- Trial name
- NCT05473819
- Testing
- Buffered Local Anesthesia, Conventional Unbuffered Local Anesthesia
- Where
- Egypt
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Neonatal Respiratory Failure
Trial of Weaning by Synchronized Ventilation
During assist control ventilation and pressure support ventilation (PSV), the start of ventilator inflation is determined by the start of the infant's inspiratory effort.
- Trial name
- NCT01376544
- Testing
- Treatment protocol designed to evaluate (SLE 5000 ventilator)
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- King's College London
Mental Distress, Insomnia
Cognitive Behavioural Therapy for Insomnia Among Young People With Moderate Level of Mental Distress in Hong Kong
This randomized controlled trial (RCT) aims to evaluate the effectiveness of a Cognitive Behavioral Therapy for Insomnia (CBTi) intervention in enhancing sleep quality, overall quality of life, functional ability, and reducing…
- Trial name
- NCT07230899
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Volunteers
- 160 people
- Sponsor
- The University of Hong Kong
Peripheral Vascular Disease
RCT to Evaluate the Renal Protective Effects of Remote Ischaemic Preconditioning in Peripheral Angioplasty
This study aims to demonstrate if remote ischaemic preconditioning (RIPC) may confer renal protection in patients undergoing peripheral angioplasty.
- Trial name
- NCT02054871
- Testing
- RIPC
- Where
- Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mid Western Regional Hospital, Ireland
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