Clinical trials: Randomized-controlled Trial
Premature Loss of Primary Second Molars, Unilateral Space Loss
Banded Helical vs Gerber Space Regainers for Unilateral Space Loss in Children
This pilot randomized controlled clinical trial will evaluate and compare Banded Helical and Gerber space regainers in children aged 7-9 years with unilateral space loss following premature loss of a primary second molar.
- Trial name
- BHR-GSR (NCT07853313)
- Testing
- Banded Helicle Space Regainer, Gerber Space Regainer
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Cairo University
Gastroenteritis, Dehydration
Study Investigating the Use of Intravenous Fluids With Dextrose for Dehydrated Children
Infants and young children often become infected with gastroenteritis leading to vomiting and diarrhea. This can lead to dehydration, one of the most common complaints in the Pediatric Emergency Department.
- Trial name
- NCT01343758
- Testing
- 5% dextrose in normal saline
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Severe Malaria
Inhaled Nitric Oxide for the Adjunctive Therapy of Severe Malaria: a Randomized Controlled Trial
Despite the use of highly effective anti-malarial medications, 10-30% of African children with severe malaria will die, underscoring the need for adjunctive therapies that can be applied in endemic areas.
- Trial name
- NCT01255215
- Testing
- Inhaled Nitric Oxide
- Where
- Uganda
- Volunteers
- 180 people
- Sponsor
- University Health Network, Toronto
Septic Shock
Anisodamine Critically Ill SeptIc Shock
Anisodamine has been widely used in China for its pharmacological effect on improving microcirculation during shock. It has been reported that anisodamine is effective in reducing mortality rate in children with meningitis.
- Trial name
- ACIdoSIS (NCT02442440)
- Testing
- anisodamine
- Where
- 15 sites in China
- Volunteers
- 355 people
- Sponsor
- Jinhua Central Hospital
Premature Ovarian Insufficiency, Ovarian Reserve Function
Therapeutic Effect of Vitamin C Supplementation in Patients With Ovarian Aging
The goal of this clinical trial is to learn if Vitamin C works to improve ovarian reserve in women with ovarian aging. It will also learn about the safety of Vitamin C.
- Trial name
- NCT06794060
- Testing
- Vitamin C (Ascorbic Acid)
- Volunteers
- 354 people
- Sponsor
- Peking University Third Hospital
Health Behavior
A Brief Outpatient Problem-solving Intervention to Promote Healthy Eating and Activity Habits in Adolescents
The purpose of this study is to refine, evaluate the feasibility, and to estimate the effect of the "healthy Living Study," a brief outpatient problem-solving intervention to promote healthy eating and activity habits in…
- Trial name
- NCT01699958
- Testing
- Problem-solving intervention
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Stanford University
Breast Cancer, Chemotherapy Effect
Simvastatin Effect in Combination With Neoadjuvant Chemotherapy to Clinical Response and Tumor-Free Margin in Locally Advanced Breast Cancer
Introduction: Neoadjuvant chemotherapy (NACT) has been the standard therapy for treating patients with locally advanced breast cancer (LABC). Doxorubicin-based regimen showed a clinical response for 70-80%.
- Trial name
- NCT04418089
- Testing
- Simvastatin 40mg
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Universitas Indonesia
Propranolol, Labour Induction
Effects of Oral Propranolol on Induction-Delivery Interval During Induction of Labour With Oxytocin
Prolonged pregnancy could lead to perinatal and maternal complications. Oxytocin has been wildly used for induction of labour, but prolonged labour continued to occur with its attendant sequelae.
- Trial name
- NCT06960850
- Testing
- Propranolol
- Where
- Nigeria
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- Federal Teaching Hospital Abakaliki
Colonoscopy
Pico-Salax Versus Poly-Ethylene Glycol for Bowel Cleanout Before Colonoscopy in Children
The purpose of this trial is to compare patient's satisfaction from Pico-Salax with the standard of care, Poly-Ethylene Glycol and electrolyte solution, for bowel cleanout before colonoscopy in children, and to compare…
- Trial name
- NCT00380497
- Testing
- PEG-Lyte®, Pico-Salax®
- Where
- Canada
- Volunteers
- 83 people
- Sponsor
- The Hospital for Sick Children
Test Anxiety
Neuman Systems Model-Based Yoga Program for Test Anxiety in Secondary School Students
This cluster randomized controlled trial evaluated the effects of a yoga program based on the Neuman Systems Model on test anxiety, quality of life, and mindfulness among eighth-grade students.
- Trial name
- NCT07644182
- Testing
- School-Based Yoga Program
- Where
- Turkey (Türkiye)
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Pregnancy, Childbirth and the Puerperium
A Pilot Randomized Controlled Trial of Repeated Hands-and-Knees Positioning During Labour
The investigators designed a pilot randomized controlled trial to assess the feasibility and acceptability of repeated hands-and-knees positioning during labour.
- Trial name
- LPT2 (NCT01720004)
- Testing
- Repeated hands-and-knees positioning during labour
- Where
- 2 sites in United States, Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Athletic Injuries, Soccer Injury
FIFA 11+ Warm-Up and Injury Risk Classification in Youth Amateur Soccer Players
This randomized controlled trial evaluated whether an eight-week, supervised FIFA 11+ neuromuscular warm-up program improves multifactorial injury risk classification, functional performance, and time-loss injury incidence in…
- Conditions
- Athletic Injuries, Soccer Injury, Lower Extremity Injury, Sprains and Strains
- Trial name
- NCT07713004
- Testing
- FIFA 11+ Neuromuscular Warm-Up Program, Routine Warm-Up
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Thyroid Diseases
Systematic Administration of Calcium and Vitamin D After Thyroidectomy
Transient hypocalcaemia consist the most common postoperative complication after thyroidectomy (10-45%). It may be mild and subclinical or cause mild or severe symptoms and may lead to longer hospital stay as well as in…
- Trial name
- NCT03777033
- Testing
- Prophylactic protocol with Ca and Vit D
- Where
- Greece
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Hellenic Red Cross Hospital
Intravenous Catheterization
The Effect of Toy IV Catheter on Children's Pain, Fear and Emotional Indicators
Aim: Research was conducted to determine the effect of preparation for the procedure with a toy IV catheter before IV catheterization in children aged 6-10 years, on children's pain, fear and emotional indicators.
- Trial name
- NCT05747833
- Testing
- Children Preparation With a Toy IV Catheter Before Peripheral Cannula application
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Type 2 Diabetes, Depression
Learning to BREATHE: A Randomized Controlled Trial to Lower Diabetes Risk in Adolescent Girls
Type 2 diabetes is a chronic disease that puts people at risk for major health problems like heart disease. Type 2 diabetes is the most common type of diabetes in adults.
- Conditions
- Type 2 Diabetes, Depression, Obesity
- Trial name
- NCT02218138
- Testing
- Learning 2 BREATHE, Colorado Blues
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Osteo Arthritis Knee, Arthroplasty, Replacement, Knee
Sharp Dissection Versus Monopolar Electrocautery in Primary Total Knee Arthroplasty Performed Under Tourniquet
This study compares the use of sharp dissection with diathermy for the approach to a total knee replacement. Half of the patients will be randomly assigned each intervention.
- Trial name
- NCT03559478
- Testing
- Sharp dissection with scalpel plus electrocautery to vessels, Electrocautery for all dissection
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Royal Infirmary of Edinburgh
Plaque Control
Triphala Tooth Wipes in Reduction of Streptococcus Mutans Colonies
This double-blind randomized clinical trial will be conducted among differently abled institutionalized children. Sixty participants aged 6-12 years with mild intellectual disability (ID) will be enrolled in the study and divided…
- Trial name
- NCT06575335
- Testing
- Triphala Tooth Wipe, Chlorhexidine Tooth Wipe
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences
Varicella
A Phase III Clinical Trial to Evaluate the Efficacy and Safety of the Live Attenuated Varicella Vaccine
The goal of this clinical trial is to evaluate the efficacy, safety and immunogenicity of a live attenuated varicella vaccine manufactured by Beijing Institute of Biological Products Co., Ltd in healthy children.
- Trial name
- NCT05669625
- Testing
- Investigational live attenuated varicella vaccine
- Where
- 13 sites in China
- Volunteers
- 12,440 people, healthy volunteers welcome
- Sponsor
- China National Biotec Group Company Limited
Cerebral Palsy (CP)
Effect of rESWT Session Frequency on Spasticity and Function Assessed by Sonoelastography in Children With Cerebral Palsy
Spasticity is a major contributor to functional limitations in children with cerebral palsy. Radial extracorporeal shock wave therapy (rESWT) has emerged as a non-invasive method for reducing spasticity; however, the optimal…
- Trial name
- CP-rESWT-FREQ (NCT07476690)
- Testing
- Real radial extracorporeal shock wave therapy (rESWT), Conventional physical therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Prostate Cancer
Comparison of Duration of Treatment Interruption With or Without Curcumin During the Off Treatment Periods in Patients With Prostate Cancer Undergoing Intermittent Androgen Deprivation Therapy
This was a placebo-controlled, double-blind, randomized trial designed with the aim of establishing whether curcumin influenced the duration of treatment interruption and rate of prostatic specific antigen(PSA) progression…
- Trial name
- NCT03211104
- Testing
- curcumin
- Volunteers
- 107 people
- Sponsor
- Samsung Medical Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.