Clinical trials: Randomized-controlled Trial
Peripheral T-cell Lymphoma
Treatment of Peripheral T-cell Lymphoma
The purpose of this study is to evaluate the efficacy and safety of GDPT regiment (gemcitabine，cisplatin,Prednisone ,Thalidomide ) for patients with Peripheral T-cell lymphoma.
- Trial name
- NCT01664975
- Testing
- GDPT regimen, CHOP regimen
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Mingzhi Zhang
Infections, Meningococcal
Trial to Assess Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Meningococcal ABCWY Vaccine as Compared to Meningococcal B Vaccine in Adolescents
The main purposes for conducting the study are firstly to assess immunological non-inferiority of the MenABCWY vaccine, administered according to 0, 2 month schedule to healthy adolescents 10 to 18 years of age, to those of the…
- Trial name
- NCT02212457
- Testing
- Bexsero, Havrix, MenABCWY
- Where
- 32 sites in United States, Finland and 1 more
- Volunteers
- 1,063 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Antibiotic-associated Diarrhea
Bacillus Particles Prevent Children Antibiotics Associated Diarrhea
This prospective, multicenter, randomized, double-blind, placebo-controlled clinical study, into the group of children in the hospital that use clinical antibiotics from one month to three years old，by observing the given…
- Trial name
- NCT02993419
- Testing
- Bacillus licheniformis Intervention
- Volunteers
- 480 people
- Sponsor
- Jiangsu Famous Medical Technology Co., Ltd.
Sleep Disturbance, Sleep Problems
Transdiagnostic Sleep Intervention to Improve Mental Health in Adolescents
This cluster randomized controlled trial will evaluate whether a brief, school-based group adaptation of the Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C) improves sleep and mental health in…
- Conditions
- Sleep Disturbance, Sleep Problems, Substance Use (Drugs, Alcohol), Anxiety
- Trial name
- SLEEP-TEEN (NCT07865728)
- Testing
- Transdiagnostic Intervention for Sleep and Circadian Dysfunction, Healthy habits psychoeducation
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Universidad Pública de Navarra
Appendicectomy
Hand-made Extracorporeal Knotting Versus Clip for Stump Closure in Laparoscopic Appendectomy
Acute appendicitis is one of the most common causes of emergency abdominal surgery. Laparoscopic appendectomy is now widely used because it offers advantages such as shorter hospital stay, less postoperative pain, and better…
- Trial name
- NCT07281612
- Testing
- Hand-made Extracorporeal Knotting, Clip Closure
- Where
- Pakistan
- Volunteers
- 190 people
- Sponsor
- Punjab Health Care Commission
Urinary Tract Infections in Children, Dexamethasone
Efficacy of Corticosteroids in Reducing Renal Scarring in Acute Pyelonephritis in Children
Urinary tract infection (UTI) is the most frequently occurring serious bacterial infection in young children and accounts 5 to 14% of emergency department visits Formation of renal scarring in children has been associated with…
- Conditions
- Urinary Tract Infections in Children, Dexamethasone, Kidney Scarring, Acute Pyelonephritis
- Trial name
- NCT04654507
- Testing
- Dexamethasone Oral
- Where
- Qatar
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Injury Prevention in Sports, Sports Performance
Effectiveness of a Judo-specific Injury Prevention Programme on Performance in Judo Athletes
Judo is a popular international combat sport with an estimated 20 million active participants world-wide and participation in judo entails a substantial risk of injury in both elite and recreational judo.
- Conditions
- Injury Prevention in Sports, Sports Performance, Sports
- Trial name
- JUDO-RCT (NCT06929377)
- Testing
- IPPON warm-up programme
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Head Injury, Traumatic Brain Injury
Outcomes of Early Versus Late Tracheostomy in Critically Ill Patients Due to Head Injury: A Randomized Controlled Trial
Tracheostomy is a surgical procedure that involves creating an opening in the trachea and bringing it to the skin surface to form a stoma. It may be performed as an emergency or elective operation.
- Trial name
- NCT07872865
- Testing
- Tracheostomy
- Where
- Iraq
- Volunteers
- 100 people
- Sponsor
- University Of Anbar
Otitis Media
Wait and See Antibiotic Prescription for Acute Otitis Media: A Randomized Controlled Trial
To determine if a wait and see prescription for ear infections in childhood reduces use of antibiotics compared to an immediate prescription
- Trial name
- NCT00250900
- Testing
- Prescription Fill Status
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Yale University
Attention Deficit Hyperactivity Disorder (ADHD)
A Random Controlled Trial of Home-based Digital Therapy for Treating ADHD in Children
Explore the interventional effects of neurofeedback games on school-aged children with mild to moderate ADHD, with the aim of providing evidence-based new methods for intervening in the core symptoms of ADHD in children.
- Trial name
- NCT07552909
- Testing
- Home-based digital therapy with brain-controlled games
- Where
- China
- Volunteers
- 146 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Colonic Adenomatous Polyps
Effectiveness and Safety of the Colonoscopy With "Visualization" Balloon
Colonoscopy has become the "gold standard" in detection of colonic polyps and colon cancer. However, colonoscopy causes significant abdominal discomfort and abdominal pain during and after the procedure, requiring intravenous…
- Trial name
- NCT02117232
- Testing
- Visualization balloon, Traditional CO2 insufflation colonoscopy
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Mercy Medical Center
Anemia
Impact of Full Correction of PTA in Renal Transplant Recipients
Background: Post-transplant anemia (PTA) might be associated cardiovascular morbidity and even increased mortality. Objectives: We aimed to assess the impact of full correction of chronic PTA on cardiovascular system and quality…
- Trial name
- NCT03861637
- Testing
- ESA for correction of PTA to 12-13g/dl
- Volunteers
- 280 people
- Sponsor
- Hamid Al-Essa Organ Transplant Center
Colonic Adenomatous Polyps
Effectiveness and Safety of the Endoscopic Removal of Large and Flat Colonic Polyps With LumenR RetractorTM
Colorectal cancer accounted for 142,570 new cancer cases and 51,370 cancer deaths in USA in 2010 and worldwide has become the third most common cancer and second leading cause of cancer related deaths.
- Trial name
- NCT02051465
- Testing
- LumenR Retractor, Removal without overtube
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Mercy Medical Center
Airway Management
Laryngoscopy for Neonatal and Infant Airway Management wIth Supplemental Oxygen at Different Flow Rates (OPTIMISE-2)
This study aims to investigate the optimal oxygen flow rate needed during tracheal intubation with the C-MAC video laryngoscope (Karl Storz, Tuttlingen, Germany) using Miller-blade or Macintosh-blade size No. 0 or No.
- Trial name
- OPTIMISE-2 (NCT05967507)
- Testing
- Low-flow nasal supplemental oxygen with a conventional nasal cannula during tracheal intubation with the C-MAC video laryngoscope, High-flow nasal supplemental oxygen (Fisher & Paykel, Auckland, New Zealand) during tracheal intubation with the C-MAC video laryngoscope
- Where
- 11 sites in United States, Australia and 5 more
- Volunteers
- 1,192 people
- Sponsor
- Thomas Riva
Irritability, Neurodevelopmental Disorders
A Scalable Trans Diagnostic Intervention Targeting Adolescent Agency Supported by Conversational AI (AGENCIA)
The aim of this clinical trial is to evaluate whether AGENCIA, a brief psychological program supported by digital technology and artificial intelligence, can help reduce emotional and behavioral difficulties in adolescents aged…
- Conditions
- Irritability, Neurodevelopmental Disorders, Impulsivity, Emotional Dysregulation
- Trial name
- AGENCIA (NCT07560072)
- Testing
- AGENCIA Digital Self-Guided, AGENCIA In-person With Digital Assistant
- Where
- Spain
- Volunteers
- 465 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Constipation
Comparison of Circular(Soave) and Heart-shaped Anastomosis in Hirschsprung's Disease
Comparison of Circular(Soave)and Heart-shaped Anastomosis in Hirschsprung's disease.
- Trial name
- NCT02234219
- Testing
- Heart-shape anastomosis, Soave anastomosis
- Where
- China
- Volunteers
- 177 people
- Sponsor
- Tongji Hospital
Substance Use Disorders
3M Study - Maria Malmö Mobile Telephone Study
The present study, in an out-patient setting for substance use treatment in adolescents, examines the effect on treatment retention of a mobile telephone follow-up technique (interactive voice response), with or without personal…
- Trial name
- NCT01706380
- Testing
- Interactive voice response with personal feedback, Interactive voice response without personal feedback
- Where
- Sweden
- Volunteers
- 73 people
- Sponsor
- Region Skane
Cycloplegic Refraction
Efficacy and Safety of Cyclopentolate Microdrops for Cycloplegic Refraction in Children
The purpose is to test the hypothesis that microdrop instillation of cyclopentolate 1% is non-inferior to standard of care, i.e., standard drop instillation of cyclopentolate 1%.
- Trial name
- NCT06885242
- Testing
- Microdrop instillation of cyclopentolate 1%, Standard drop instillation of cyclopentolate 1%
- Where
- Greece
- Volunteers
- 63 people
- Sponsor
- Aristotle University Of Thessaloniki
Dental Procedures
Virtual Reality vs. Standard-of-Care for Comfort During Dental Procedures in Children
Children sometimes need dental procedures which can be painful and associated with child pain and anxiety. In addition to pain medication, distraction may help children cope with the pain.
- Trial name
- NCT03862573
- Testing
- Virtual Reality
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- University of British Columbia
Periodontal Pocket, Periodontitis
Use of Ozone Gel as an Antimicrobial in Treatment of Periodontitis
Periodontitis is an inflammatory disease that destroys tooth-supporting structures through oral bacterial plaque. ozone gel's act as an antimicrobial effect as an adjunct to conventional periodontal therapy (scaling and root…
- Trial name
- NCT05905445
- Testing
- ozone gel
- Where
- Iraq
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Ghufran Falih Hassan
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.