Clinical trials: Randomized-controlled Trial
Scabies
Better Disease Control by Multidrug Regimen in Scabies
Scabies is associated with significant discomfort and social taboo. Existing treatment regimen frequently fails due to lack of patient compliance.
- Trial name
- NCT05198947
- Testing
- Permethrin Lotion 5%, Permethrin Lotion 5% and Oral Ivermectin 200 mcg/kg
- Volunteers
- 212 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Randomized Controlled Trial
Web-based Tool to Improve Reporting of Randomized Controlled Trials
The CONSORT (Consolidated Standards of Reporting Trials) Statement aims to improve the reporting of randomized trials. If trials are not well reported it is difficult for clinicians to use best evidence to inform clinical…
- Trial name
- WebCONSORT (NCT01891448)
- Testing
- WebCONSORT tool, Modified WebCONSORT tool
- Where
- 2 sites in France, United Kingdom
- Volunteers
- 324 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Growth, Infections
Effects of an Infant Formula and follow-on Formula Containing Bio-active Ingredients on Growth, Tolerance and Infections
In this clinical trial, the growth (weight for age), product tolerance (product intake, comfort) and infection-related symptoms of healthy infants consuming an IF and FOF containing bio-active ingredients will be evaluated and…
- Trial name
- NCT06137235
- Testing
- cows milk infant formula and follow-on formula with bioactive ingredients, standard cows milk infant formula and follow-on formula
- Where
- 3 sites in Greece
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- FrieslandCampina
Pregnancy, Prematurity
Clindamycin to Reduce Preterm Birth in a Low Resource Setting
Preterm birth has been linked to certain types of vaginal infections. The goal of this study is to determine if giving women pregnant between 13-20 weeks with an elavated vaginal pH(evidence of this type of infection)Oral…
- Conditions
- Pregnancy, Prematurity, Preterm Birth, Bacterial Vaginosis
- Trial name
- NCT01800825
- Testing
- Clindamycin
- Where
- India
- Volunteers
- 1,726 people
- Sponsor
- Christiana Care Health Services
Pediatric Obesity, Mobile Technology
An Addiction-Based Mobile Health Weight Loss Intervention With Coaching
The proposed multi-site randomized control trial (RCT) will test the effectiveness of an addiction-based weight loss intervention, embodied first as a smartphone app with telephone coaching and second as an identical approach…
- Conditions
- Pediatric Obesity, Mobile Technology, Addiction
- Trial name
- NCT03500835
- Testing
- App, Coaching, Clinic: Modified KidsNFitness
- Where
- United States
- Volunteers
- 161 people
- Sponsor
- Children's Hospital Los Angeles
Vocal Fold Nodules
Randomized Controlled Trial of Voice on Children With Vocal Nodules
The primary objective of this study is to determine the impact of voice therapy on voice-related quality of life in children age 6-10 years old with apparent vocal fold nodules, as measured by the validated Pediatric…
- Trial name
- NCT01255735
- Where
- 4 sites in United States, Canada
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Respiration, Artificial, Ventilator Weaning
Pressure Support Reduction Versus Spontaneous Breathing Trials in Weaning From Ventilation
This study is a comparison of two most commonly used modes of weaning and the outcomes in the two groups.
- Trial name
- NCT00911378
- Testing
- Pressure support ventilation, Spontaneous breathing trials
- Where
- India
- Volunteers
- 130 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Breastfeeding
Maxolon to Improve Breastmilk Supply in Diabetic Women: a Randomised Controlled Trial
Early use of oral maxalon can hasten and improve the establishment of breastfeeding in diabetic mothers after preterm and term deliveries.
- Trial name
- Maxalon (NCT00477776)
- Testing
- Metoclopramide (Maxolon)
- Where
- Singapore
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Preeclampsia
Aggressive Versus Expectant Management of Severe Preeclampsia Remote From Term
How best to manage preeclampsia remote from term is controversial because of conflicting maternal and neonatal risks. Gestational age is the most important determinant of neonatal outcome.
- Trial name
- MEXPRE-Latin (NCT01164852)
- Testing
- Delivery
- Where
- 8 sites in Ecuador, Guatemala and 4 more
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Complejo Hospitalario Dr. Arnulfo Arias Madrid
Inflammatory Bowel Disease, Ulcerative Colitis
Pediatric FEcal Microbiota Transplant for Ulcerative Colitis
The PediFETCh study is a pilot trial designed to assess the feasibility of fecal microbiota transplants for the therapy of pediatric ulcerative colitis (UC) and pediatric inflammatory bowel disease-unclassified (IBD-U).
- Trial name
- PediFETCh (NCT02487238)
- Testing
- Fecal Microbiota Enema, Normal Saline Enema
- Where
- 3 sites in Canada
- Volunteers
- 35 people
- Sponsor
- McMaster Children's Hospital
Anxiety, Dental
Comparative Evaluation Between the Effectiveness of Vibration Assisted Syringe and Conventional Syringe
The study will be conducted to evaluate the effect of the vibration assisted syringe on pain perception and anxiety in children during intra oral injection of local anesthesia in comparison with conventional syringe.
- Trial name
- NCT04215055
- Testing
- vibraject
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Accretions; Teeth
Effects of Micro-osteoperforation on the Maxillary First Molar Distalization
the study aimed to evaluate the effect of different types of Micro-osteoperforation on the rate of distal movement of maxillary first molars as a primary out come.
- Trial name
- NCT05167708
- Testing
- Micro-osteoperforation
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Sepsis, Gastroenteritis
Utility of Ultrasound Assessment of the Inferior Vena Cava in Patients With Sepsis and Dehydration
Conduct a randomized, controlled trial looking at how the use of ultrasound analyzing the inferior vena cava impacts the management and outcomes of pediatric emergency department patients undergoing evaluation and treatment of…
- Conditions
- Sepsis, Gastroenteritis, Dehydration
- Trial name
- NCT02568189
- Testing
- SonoSite Maxx Series Ultrasound System
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Family Witnessed Resuscitation, Empathy Education
VIDEO LEARNING FOR EMPATHY, ETHICS AND FAMILY WITNESSED RESUSCITATION
This clinical trial (randomized controlled experimental study) aims to learn about the effects of presenting the family-witnessed CPR process from a patient's perspective through 360° virtual reality and 2D video within…
- Conditions
- Family Witnessed Resuscitation, Empathy Education, Ethics Nursing, Education Nursing
- Trial name
- NCT07692568
- Testing
- 360 Degree Virtual Reality Video, 2D Standard Video
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Kocaeli Sağlık ve Teknoloji Üniversitesi
Epilepsy, Treatment
Probiotic in Treatment of Adult Patients With Drug-resistant Epilepsy
This study is a randomized, double-blind parallel group placebo-controlled clinical trial with the aim of investigating the effect of probiotic versus placebo on drug-resistant adult patients with epilepsy.
- Trial name
- NCT05160350
- Testing
- Probiotic
- Where
- Iran
- Volunteers
- 42 people
- Sponsor
- Mazandaran University of Medical Sciences
Cerebral Palsy, Autism
Rehabilitation of Children With Multiple Disabilities
The objective of the study is to compare the usual care and treatment of children and youth (0-19 years) with multiple developmental delays and disabilities and their families in Simcoe York with a co-ordinated, navigated…
- Conditions
- Cerebral Palsy, Autism, Down's Syndrome, Brain Injury
- Trial name
- NCT01379443
- Testing
- CTN model of care for children and their families
- Where
- Canada
- Volunteers
- 445 people
- Sponsor
- Children's Treatment Network
Severe Pneumonia
Feasibility and Acceptability Followed by Effectiveness of bCPAP for Treatment of Children Aged 1-59 Months With Severe Pneumonia in Ethiopia
Principal Investigator: Mohammod Jobayer Chisti Research Protocol Title: Feasibility and Acceptability Followed by Effectiveness of Bubble Continuous Positive Airway Pressure (bCPAP) for Treatment of Children aged 1-59 months…
- Trial name
- NCT03870243
- Testing
- Bubble CPAP, Low flow oxygen
- Where
- Bangladesh
- Volunteers
- 1,240 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Toe Flexor Strength
Improving Foot Strength in Vocational Ballet Dancers
Professional dancers subject their feet to high forces through frequent jumping, repeated heel rises, insufficient shoe cushioning, and a high degree of foot mobility.
- Trial name
- NCT06589050
- Testing
- "Toe flexor device" experimental group, "Inclined Heel Rise" experimental group
- Where
- United Kingdom
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Bern
Systemic Lupus Erythematosus
A Study of Telitacicept for the Treatment of Moderately to Severely Active Systemic Lupus Erythematosus (REMESLE-1)
The purpose of this study is to evaluate the efficacy and safety of telitacicept in the treatment of moderately to severely active SLE.
- Trial name
- NCT05306574
- Testing
- Telitacicept
- Where
- 78 sites in United States, Argentina and 13 more
- Volunteers
- 91 people
- Sponsor
- Vor Biopharma
Tracheal Intubation Morbidity
Videolaryngoscopy vs. Direct Laryngoscopy for Elective Airway Management in Pediatric Anesthesia
Videolaryngoscopy can lead to superior airway conditions and to the possible higher success compared to standard direct laryngoscopy.
- Trial name
- Videoscopy (NCT03747250)
- Testing
- Videolaryngoscopy, Direct laryngoscopy
- Where
- Czechia
- Volunteers
- 501 people
- Sponsor
- Brno University Hospital
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