Clinical trials: Randomized-controlled Trial
Class II Division 1 Malocclusion
Patient Outcomes Associated With Two Accelerated Method of Retraction of Upper Front Teeth
This study aimed to evaluate the levels of pain, discomfort, and functional impairment associated with traditional corticotomy and flapless corticotomy in the retraction of upper anterior teeth.
- Trial name
- NCT05928143
- Testing
- Traditional corticotomy, Flapless corticotomy
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Hyponatremia, Hypernatremia
Comparison of Isotonic Versus Hypotonic Fluids in Neonates for Maintenance Fluid Therapy After Surgery
The goal of this clinical trial is to determine if isotonic or hypotonic fluids are more effective in maintaining serum sodium levels in neonates undergoing maintenance fluid therapy post-surgery.
- Conditions
- Hyponatremia, Hypernatremia, Postoperative Care in Neonates, Edema
- Trial name
- NCT06484608
- Testing
- Isotonic Saline with Dextrose
- Where
- Pakistan
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Medical College
Down Syndrome
Inspiratory Muscle Training and Physical Fitness in Children With Down Syndrome Randomized Control Trial
The purpose of this study is to investigate the effect of inspiratory muscle training on physical fitness in Down syndrome children.
- Trial name
- NCT04767412
- Testing
- aerobic exercise training, inspiratory muscle training
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Undesired Intrauterine Pregnancy, First Trimester Pregnancy
Trial Comparing Intravenous and Oral Moderate Sedation for First Trimester Surgical Abortions
In the United States, the majority of first-trimester surgical abortions are performed in outpatient clinics that utilize a wide variety of oral and intravenous regimens for pain control.
- Trial name
- NCT01011634
- Testing
- Intravenous moderate sedation versus oral medication
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Rumination Syndrome
Baclofen for Children With Rumination Syndrome
The goal of this clinical trial is to learn about baclofen in pediatric patients with rumination syndrome. The main question it aims to answer is whether baclofen is effective in treating children with rumination syndrome.
- Trial name
- NCT05975684
- Testing
- Baclofen
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Calf Muscle Tightness
Neural Mobilisation Effect on Calf Muscle
The purpose of this study was to investigate Neural mobilisation effects on calf muscles length and strength is crucial to optimize ballet performance and prevent injuries.
- Trial name
- NCT07585084
- Testing
- Neural mobilisation, Gastrocnemius stretching
- Where
- Malaysia
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- INTI International University
Hearing Loss, Bilateral
Hearing Intervention Effects on Brain and Language Development in Children With Bilateral Mild Hearing Loss
This is a multicenter, prospective, randomized controlled clinical trial to evaluate the effects of hearing aid intervention on brain and language development in children with bilateral mild sensorineural hearing loss.
- Trial name
- HBD-RCT (NCT07774728)
- Testing
- Behind-the-ear (BTE) hearing aids, Hearing-care educational sessions
- Where
- 12 sites in China
- Volunteers
- 258 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Pediatric Crohn's Disease
Low Dose Oral Methotrexate in Pediatric Crohn's Disease Patients Initiating Anti-Tumor Necrosis Factor (Anti-TNF) Therapy
The purpose of this study is to determine whether adding low dose methotrexate to anti -TNF therapy is more effective than treatment with anti-TNF therapy alone in inducing and maintaining steroid-free remission for children with…
- Trial name
- COMBINE (NCT02772965)
- Testing
- Methotrexate
- Where
- 32 sites in United States
- Volunteers
- 306 people
- Sponsor
- University of North Carolina, Chapel Hill
Cerebral Palsy, Cognitive Orientation
The Effect of the CO-OP Approach for Children With Cerebral Palsy
In the literature, despite the reported positive findings of the Cognitive Orientation to daily Occupational Performance (CO-OP) approach, studies in this area have been limited and it is stated that studies involving more sample…
- Trial name
- NCT04308200
- Testing
- CO-OP approach, NDT
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- ZEYNEP KOLİT
Suicidal Ideation
Pilot Trial of Mobile Technology for Adolescent Suicidality
The primary objective of this study is to assess the efficacy of a digital intervention in reducing suicidal ideation in adolescents.
- Trial name
- NCT06454136
- Testing
- OTX-207, Comparator App + Treatment as Usual (TAU)
- Where
- 3 sites in United States
- Volunteers
- 228 people
- Sponsor
- Oui Therapeutics, Inc.
Abortion, Induced
Mifepristone Versus Laminaria for Cervical Ripening in Midtrimester Induction
Data from other countries have suggested that oral mifepristone used as a cervical ripening agent may decrease induction to delivery time in midtrimester inductions.
- Trial name
- NCT00383032
- Testing
- mifepristone
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Pain, Postoperative, Developmental Dysplasia of the Hip
Postoperative Analgesic Effect of Two Peripheral Nerve Blocks for Hip Surgery in Pediatrics
Hip joint surgery for developmental dysplasia of the hip (DDH) in children is extremely painful and associated with considerable postoperative pain despite the use of systemic opioids.
- Conditions
- Pain, Postoperative, Developmental Dysplasia of the Hip, Regional Anesthesia Morbidity
- Trial name
- NCT05348421
- Testing
- FTPB, PENG Block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Patients Who Gain Weight or Stop Losing Weight After barıatrıc Surgery, Absence of Cognitive or Psychiatric Illness
THE EFFECT OF MOTİVATİONAL INTERVİEWİNG-BASED MİNDFULNESS INTERVENTION ON WEİGHT MANAGEMENT AFTER WEİGT LOSS,7SLİMMİNG SURGERY: A RANDOMİZED CONTROLLED TRIAL.
Obesity is one of the most critical health problems in developed and developing countries, recognized as a chronic disease that adversely affects both individual and societal health.
- Conditions
- Patients Who Gain Weight or Stop Losing Weight After barıatrıc Surgery, Absence of Cognitive or Psychiatric Illness, Not Having Previously Received Cognitive Awareness Training, Not Having Undergone Revision Surgery
- Trial name
- NCT07351214
- Testing
- A MİNDFULNESS İNİTİATİVE BASED ON MOTİVATİONAL İNTERVİEWİNG
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Duygu Ateş
Psychiatric Disorder, Mental Health Issue
The Impact of Running Therapy on Mental Health of Youth in a Psychiatric Adolescent Department
A randomized controlled trial, whereby the intervention group will participate in a 12-week running program and will also continue their routine treatment program. The control group will continue the treatment program as usual.
- Trial name
- NCT05430607
- Testing
- Running therapy
- Where
- Israel
- Volunteers
- 18 people
- Sponsor
- Tali Bertler
Attention Deficit Hyperactivity Disorder
Improving Self-regulation in Individuals With ADHD Through Adapted Karate Training
The goal of this clinical trial is to examine the effectiveness of Adaptive Karate Training (AKT) in improving self-regulation and daily function in children with ADHD, exploring the underlying mechanisms.
- Trial name
- NCT07430436
- Testing
- Adapted karate training
- Where
- Israel
- Volunteers
- 55 people
- Sponsor
- Tel Aviv University
Depression, Anxiety
Progressive Muscle Relaxation in Nursing Students: Effects on Psychological and Biopsychosocial Outcomes
This randomised controlled trial aims to investigate the effects of progressive muscle relaxation exercises (PMRE) on depression, anxiety, stress, future-oriented attitudes, and biopsychosocial responses in nursing students.
- Conditions
- Depression, Anxiety, Stress, Psychological, Mental Health
- Trial name
- PRMNURSE (NCT07038109)
- Testing
- Progressive relaxation exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Development Coordination Disorder
Active Video Games in Children With DCD
Developmental Coordination Disorder (DCD) is a condition that affects a child's ability to perform coordinated motor activities and may also impact visual perception and motor planning skills.
- Trial name
- NCT07631832
- Testing
- Active Video Game Training, Conventional Occupational Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- ZEYNEP KOLİT
Respiratory Distress Syndrome
High Flow Nasal Cannula in Comparison With Nasal Continuous Positive Airway Pressure in the Management of Respiratory Distress Syndrome
To compare the primary outcome, failure of extubation defined by the need for re-intubation and mechanical ventilation within 5 days of initial extubation and secondary outcomes, morbidities and mortality after using of heated…
- Trial name
- NCT02587832
- Testing
- HHHFNC, NCPAP
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Sidra Medicine
Hand Hygiene
Education Program of Hand Hygiene for Nursing Students
The goal of this observational study is to design and test a multicomponent education program of hand hygiene in nursing students. The main aims are: 1.
- Trial name
- NCT05872581
- Testing
- Hand scanner instant feedback, Video training
- Where
- Hong Kong
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Polycystic Ovary Syndrome (PCOS) Women, Obesity
Semaglutide in Women With Polycystic Ovary Syndrome and Obesity
Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder that is frequently associated with metabolic features, including obesity.
- Trial name
- NCT06896981
- Testing
- Metformin with Semaglutide
- Where
- Bangladesh
- Volunteers
- 31 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
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