Clinical trials: Randomized-controlled Trial
Caries
Effectiveness of an ICCMS™ Caries Management Program.
The aim of this study is to compare in schoolchildren the effectiveness of an updated caries management program based on the current caries paradigm with the ICCMS™ system (International Caries Classification and Management…
- Trial name
- NCT04676230
- Testing
- Experimental group, Control group
- Where
- Colombia
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Universidad El Bosque, Bogotá
Mandibular Advancement
Sensory Re-Training Following Facial Surgery for Correction of Facial Skeletal Disharmony
The purpose of this study is to determine whether facial exercises in conjunction with opening exercises routinely provided after facial surgery to correct a facial skeletal disharmony will shorten the time until a patient…
- Trial name
- NCT00078507
- Testing
- Sensory Re-training, Sensory Retraining, Opening Exercises
- Where
- 2 sites in United States
- Volunteers
- 186 people
- Sponsor
- University of North Carolina, Chapel Hill
Prevention Program, Wait List Control
School-Based Eating Disorder Prevention
This is a cluster randomized controlled trial with two assessment points (baseline and 24-week follow-up) comparing the Claudia Carraro prevention program to a no-intervention control group.
- Trial name
- NCT07158593
- Testing
- Claudia carraro prevention program
- Where
- Italy
- Volunteers
- 1,205 people
- Sponsor
- Villa Garda Hospital
Prostate Cancer
Non-inferiority Trial Omitting Drainage After Robot-assisted Radical prostatectomY
This is a multicenter, prospective, randomized, controlled, open-label, assessor-blinded, non-inferiority trial evaluating whether pelvic drainage can be safely omitted after robot-assisted radical prostatectomy (RARP).
- Trial name
- POND-RARP (NCT07887321)
- Testing
- No Pelvic Drain Placement, Pelvic Drain Placement
- Where
- 3 sites in China
- Volunteers
- 400 people
- Sponsor
- Shanghai East Hospital
Neonatal Intubation Performance
Impact of Stress on Performance of Neonatal Endotracheal Intubation
This study will be a randomized controlled trial designed to analyse the impact of stress on the success rate of a simulated neonatal endotracheal intubation.
- Trial name
- NCT02758704
- Testing
- High stress, Low stress, Endotracheal intubation on mannequin
- Where
- 2 sites in Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Family Violence, Domestic Violence
How Can Child Health Services Identify and Respond to Family Violence
Family violence has severe impacts on children's health and development. The Child Health Services (CHS) in Sweden reaches almost 100% of families with young children and provides a unique setting to facilitate identification of…
- Conditions
- Family Violence, Domestic Violence, Intimate-partner Violence
- Trial name
- NCT06299501
- Testing
- Routine questions, Questions on evidence based indication, Treatment as usual
- Where
- Sweden
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Functional Abdominal Pain Syndrome, Abdominal Pain
A Randomized-controlled Study of a Cognitive-behavioral Intervention for Children With Functional Abdominal Pain
This trial aims to compare two training programs for children suffering functional abdominal pain. These two programs are comparable in number of sessions and group sizes, but show differences in content (very focused on pain…
- Trial name
- Stop-FAP (NCT02030392)
- Testing
- Intervention group, Active control group
- Where
- 6 sites in Germany
- Volunteers
- 127 people
- Sponsor
- University of Potsdam
Supracondylar Humerus Fractures, Nerve Examination
Rock-Paper-Scissors-OK in Nerve Examination
Patients presenting to the Orthopedics and Traumatology Clinic of Ankara Bilkent City Hospital with supracondylar humerus (elbow) fractures will initially undergo closed reduction.
- Trial name
- NCT07480798
- Testing
- Conventional Neurological Examination, Preoperative video-based training module
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Ankara City Hospital Bilkent
Dental Caries in Children
Evaluation of the Antibacterial Effect of Probiotics on Cariogenic Bacteria in Children
This randomized controlled clinical trial aims to evaluate the effect of oral probiotic lozenges containing Streptococcus salivarius, Lactobacillus reuteri, and Lactobacillus paracasei on cariogenic bacteria (Streptococcus…
- Trial name
- NCT07904221
- Testing
- Probiotic lozenges containing Streptococcus salivarius, Lactobacillus reuteri, and Lactobacillus paracasei, Xylitol-based moisturizing lozenges
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Developmental Delay
Development and Effectiveness of Home-based Programs for Preschool Children With Developmental Delay
Early intervention refers to the provision of early detection, early diagnosis, and early intervention for infants and young children with special needs.
- Trial name
- NCT02115334
- Testing
- professional therapists delivering the PHPA, parents executing the PHPA, health education
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Vitamin D Deficiency
Effects of Vitamin D Dose and Genotype of the Binding Protein in Infants and Children
The purpose of this study is to determine if the vitamin D binding protein genotype influences circulating vitamin D levels and if it may have functional consequences on vitamin D activity.
- Trial name
- VitaD (NCT01050387)
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Yale University
Seasonal Influenza
Clinical Trial to Evaluate the Safety and Immunogenicity of Quadrivalent Influenza Vaccine (15µg/0.5ml)
The purpose of this study is to evaluate the safety and immunogenicity of quadrivalent influenza vaccine in healthy subjects aged over 3 years
- Trial name
- NCT03853993
- Testing
- Quadrivalent influenza vaccine, Trivalent influenza vaccine (contains B/Victoria strain), Trivalent influenza vaccine (contains B/Yamagata strain)
- Where
- 2 sites in China
- Volunteers
- 2,380 people, healthy volunteers welcome
- Sponsor
- Sinovac Biotech Co., Ltd
Anterior Cruciate Ligament Injury
Motor Imagery to Facilitate Sensorimotor Relearning After ACL Injury
Anterior cruciate ligament injury is a common issue in sports involving cutting and jumping. Treatment may include surgical intervention followed by physical therapy, or no surgical intervention with the main treatment being…
- Trial name
- MOTIFS (NCT03473821)
- Testing
- MOTIFS
- Where
- Sweden
- Volunteers
- 106 people
- Sponsor
- Lund University
Autism Spectrum Disorder
Study of Two Exercises Protocols for Autism Spectrum Disorder
Introduction: Autism Spectrum Disorder (ASD) is characterized as a neurodevelopmental disorder, with motor symptoms that may predispose to falls and gait changes.
- Trial name
- STEP-TEA (NCT05908357)
- Testing
- Exergaming, Booklet
- Where
- Brazil
- Volunteers
- 22 people
- Sponsor
- Federal University of Bahia
Idiopathic Scoliosis
Effect of Bifidobacterium Breve Supplementation on the Onset and Progression of Idiopathic Scoliosis
Researchers hypothesized that Bifidobacterium breve Supplement could reduce the progression rate of idiopathic scoliosis in children and potentially prevent the occurrence of new cases of scoliosis.
- Trial name
- NCT07466511
- Testing
- Bifidobacterium breve, Lifestyle Education
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Pediatric Cancer
WASPE Sleep Adjustment for Children Aged 0-4 Years Undergoing Radiation Therapy
This prospective, randomized controlled feasibility trial aims to evaluate the feasibility and effectiveness of a behavioral sleep adjustment protocol (WASPE: Watching videos, Activities outdoors, Stimulation to stay awake…
- Trial name
- NCT06443632
- Testing
- WASPE Sleep Adjustment Protocol, Chloral Hydrate
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Shandong Cancer Hospital and Institute
Arthritis, Osteoarthritis
The SOAR (Stop OsteoARthritis) Program Proof-of-Concept Study
Adolescents and young adults who hurt their knees playing sports or doing recreational activities can develop joint damage, muscle weakness, inactivity, and weight gain which might lead to an increased risk of osteoarthritis…
- Conditions
- Arthritis, Osteoarthritis, Arthritis Knee, Osteo Arthritis Knee
- Trial name
- SOARPOC (NCT04956393)
- Testing
- Immediate 8-Week SOAR Program, Delayed 8-Week SOAR Program
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Type 1 Diabetes Mellitus
Examining the Influence of Guided Meditation on Diabetes-related Distress and Glycemic Control
The study aims to investigate the effects of Guided Meditation on diabetes-related distress and glycemic control in hospitalized Type 1 adolescent diabetic patients.
- Trial name
- NCT06151821
- Testing
- Guided meditation
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Shifa International Hospital
Antibiotic Side Effect
Evaluation of Bifidobacterium Breve PRL2020 in Preventing Antibiotic-Associated Side Effects From Amoxicillin or Amoxicillin/Clavulanic Acid
This study aims to evaluate the efficacy and safety of the probiotic Bifidobacterium breve PRL2020 in preventing gastrointestinal and extra-intestinal side effects caused by Amoxicillin or Amoxicillin/Clavulanic Acid in pediatric…
- Trial name
- NCT06850714
- Testing
- Bifidobacterium breve PRL2020 (Brevicillin®), Amoxicillin or Amoxicillin/Clavulanic Acid
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Allergic Rhinitis, Perennial Allergic Rhinitis
Clinical Trial to Evaluate the Safety and Efficacy of AGR Tablet as a Treatment of Perennial Allergic Rhinitis in Korean
The purpose of this study is to evaluate treatment of perennial allergic rhinitis in Korean patients with AGR tablet.
- Conditions
- Allergic Rhinitis, Perennial Allergic Rhinitis, Non-seasonal Allergic Rhinitis
- Trial name
- NCT01982916
- Testing
- AGR tablet, Active Comparator
- Where
- 9 sites in South Korea
- Volunteers
- 324 people
- Sponsor
- Ahn-Gook Pharmaceuticals Co.,Ltd
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