Clinical trials: Randomized-controlled Trial
Deep Caries
Multicenter Trial Comparing One-step Partial Caries Removal to Complete Caries Removal for the Treatment of Deep Carious Lesions in Permanent Teeth. (DECAT : DEep CAries Treatment).
This clinical trial is a national multicenter randomized controlled trial performed in parallel groups aiming to validate a treatment that preserves pulp vitality of mature permanent posterior teeth through partial removal of…
- Trial name
- DECAT (NCT02286388)
- Testing
- A one-step partial caries removal procedure for the treatment of deep carious lesions in posterior permanent teeth., A complete caries removal procedure for the treatment of deep carious lesions in posterior permanent teeth., The application of an antibacterial dental adhesive (ClearfilTM SE Protect, Kuraray Dental).
- Where
- 15 sites in France
- Volunteers
- 464 people
- Sponsor
- Hospices Civils de Lyon
Bronchial Asthma
Study of MG-ZG122 Humanized Monoclonal Antibody in Asthma Subjects
A Randomized, Double-Blind, Placebo-Controlled Phase II Clinical Trial to Evaluate the Efficacy and Safety of MG-ZG122 Humanized Monoclonal Antibody Injection in Asthma Subjects, with Dosing Every 12 or 24 Weeks for 48 Weeks
- Trial name
- NCT07054034
- Testing
- MG-ZG122 Humanized Monoclonal Antibody Injection
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Shanghai Mabgeek Biotech.Co.Ltd
Attention Deficit Hyperactivity Disorder
Standardized Lycium Chinense Fruit Extract Enhances Attention and Cognitive Function in Healthy Young People
Lycium chinense fruit (LCF) is widely distributed in East Asia that has been used traditionally for anti-aging purposes. This study was performed to examine the effects of LCF on attention and cognitive function in healthy young…
- Trial name
- NCT03439111
- Testing
- Standardized Lycium chinense Fruit Extract (LCF) capsules
- Where
- South Korea
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Biomix
Complete Uterine Evacuation After Use of Study Drugs
Medical Abortion With Mifepristone + Misoprostol (13 - 22 Weeks)
A double-blind randomized controlled trial to compare a shorter interval between the administration of mifepristone and misoprostol (simultaneous administration compared to 24hours from administration of mifepristone to receipt…
- Trial name
- NCT01768299
- Testing
- Mifepristone, Misoprostol
- Where
- 3 sites in Vietnam
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Substance Use Disorders
Effect of Mindfulness-Based Relapse Prevention Program on Readiness for Change and Self-efficacy Among Clients With Substance Use Disorders
The treatment process of substance addiction is applied principally by psychiatrists, psychologists, and psychiatric mental health nurses. In this respect, psychiatric mental health nurses have a crucial role to play.
- Trial name
- NCT05990699
- Testing
- Mindfulness-Based Relapse Prevention program
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
Gynecology, Gynecology/Obstetrics Conditions
Gynaecological Examination Gown and Patient Satisfaction
The attitude of the health personnel before, during and after the examination and the positive examination experience of the person have a significant impact on ensuring the continuity of the subsequent examination and increasing…
- Trial name
- NCT06324019
- Testing
- putting on an examination gown
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- ayşegül muslu
Gastro Esophageal Reflux
Effect of Right Lateral Position on Ventilated Preterm Neonates
Objective: to evaluate the effect of right lateral positioning in comparison with supine positioning on tracheal aspirate pepsin levels as a marker of aspiration of gastric contents in ventilated preterm neonates.
- Trial name
- NCT03258528
- Testing
- positioning
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Osteomyelitis
Dalbavancin vs Comparator in Pediatric Subjects With Acute Hematogenous Osteomyelitis
Dalbavancin for Pediatric Osteomyelitis
- Trial name
- AHOM (NCT02344511)
- Testing
- Dalbavancin, cefazolin, nafcillin, oxacillin or vancomycin
- Sponsor
- Durata Therapeutics International BV (an Affiliate of Actavis, Inc.)
Ventilator Lung
Effect of Sustained Inflations on Lung Atelectasis During Pediatric Laparoscopic Surgery
The aim of our study is to assess the beneficial effect of sustained inflations as a recruitment manoeuvre, using LUS examinations, on the degree of lung atelectasis that occurs in pediatric patients undergoing laparoscopic…
- Trial name
- NCT05647434
- Testing
- sustained inflations
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Pain, Fear
The Effect of Buzzy® and a Stress Ball on Reducing Pain and Fear During Peripheral Intravenous Cannulation in Children
This study aims to compare the effects of Buzzy®, a device that applies cold and vibration, and a stress ball on pain and fear during intravenous catheter insertion in children aged 7-12 years.
- Conditions
- Pain, Fear, Pain Management
- Trial name
- NCT07851909
- Testing
- Buzzy, Stress Ball
- Where
- Turkey (Türkiye)
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Amblyopia
CURESIGHT BINOCULAR AMBLYOPIA TREATMENT STUDY
Screening A child is considered for the study after undergoing a standard of care and study specific eye examinations (by a study investigator as part of standard of care) that identifies amblyopia appearing to meet the…
- Trial name
- NCT04785690
- Testing
- CureSight, Patching
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- NovaSight
Pain, Acute, Procedural Pain
Neonatal Pain Management and Pain Monitoring Using New Methods
The aim of this randomized controlled study with crossover design is to examine the effectiveness of mother-driven interventions, skin-to-skin contact (SSC) and recorded mother's heartbeats as sound and vibration (MHB), compared…
- Conditions
- Pain, Acute, Procedural Pain, Infant
- Trial name
- NCT04967118
- Testing
- Skin-to-skin contact, Mother's heartbeats as sound and vibration, 30% oral glucose
- Where
- Finland
- Volunteers
- 36 people
- Sponsor
- University of Oulu
Osteoporosis
A Randomized Controlled Trial of a Bone Density Decision Aide
This research study is being conducted to determine if a modified bone mineral density (BMD) test report that contains additional fracture risk information will be a useful physician decision aide in selecting patients for…
- Trial name
- NCT00285168
- Testing
- Bone Density Decision Aide
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Manitoba
Dental Pulp Exposure
Comparative Evaluation of Clinical and Radiographic Outcomes of Mustard Gel (Brassica Nigra) and Mineral Trioxide Aggregate (MTA) as Pulpotomy Agents in Deciduous Molars- A Randomized Controlled Trial
The aim of this clinical trial is to compare two materials to treat baby molars with deep cavities. When the cavity is very deep and reaches the nerve of a baby tooth, dentist perform a treatment called "Pulpotomy".
- Trial name
- MG-MTA-RCT2026 (NCT07557290)
- Testing
- Intervention 1: Mustard Gel, Intervention 2 : Mineral Trioxide Aggregate (MTA)
- Volunteers
- 72 people
- Sponsor
- Dr Nida Farooq
Breast Cancer
A Study to Investigate the Effects of Tibolone (Livial®) on Breast Tissue in Postmenopausal Women With Breast Cancer (Study 32971)(P06469)
The primary purpose of this study is to compare changes in the expression of the proliferation marker Ki-67 in malignant breast tissue after treatment with tibolone or placebo in postmenopausal women who need to undergo surgery…
- Trial name
- STEM (NCT00725374)
- Testing
- tibolone
- Volunteers
- 102 people
- Sponsor
- Organon and Co
Obesity, Childhood, Hypertension
Family Meals on Prescription- a Randomized Controlled Trial
"Matkassen - effekten av tre månaders intensiv kostintervention hos barn med fetma/ Family Meals on Prescription.- a randomized controlled trial : The aim of the study was to explore a novel approach for the treatment of obesity…
- Conditions
- Obesity, Childhood, Hypertension, Metabolic Syndrome, Dietary Habits
- Trial name
- NCT05225350
- Testing
- Dietary Intervention
- Where
- Sweden
- Volunteers
- 89 people
- Sponsor
- Göteborg University
Colic
Human Milk Oligosaccharide (HMO) Supplementation in Colic Management
Efficacy and tolerability of a composition comprising of HMO in a supplement format on colic management: a double-blind, randomized, placebo-controlled trial
- Trial name
- NCT05554991
- Testing
- HMO, Parental reassurance and support
- Where
- 7 sites in Italy, Spain
- Volunteers
- 5 people
- Sponsor
- Société des Produits Nestlé (SPN)
Warts
Salicylic Acid Versus Cryotherapy for the Treatment of HPV1-induced Plantar Warts
To evaluate whether salicylic acid was superior to cryotherapy for plantar warts
- Trial name
- NCT05617950
- Testing
- salicylic acid, cryotherapy
- Volunteers
- 174 people
- Sponsor
- The 306 Hospital of People's Liberation Army
Systemic Lupus Erythematosus
A Study of Telitacicept for the Treatment of Moderately to Severely Active Systemic Lupus Erythematosus (REMESLE-1)
The purpose of this study is to evaluate the efficacy and safety of telitacicept in the treatment of moderately to severely active SLE.
- Trial name
- NCT05306574
- Testing
- Telitacicept
- Where
- 78 sites in United States, Argentina and 13 more
- Volunteers
- 91 people
- Sponsor
- Vor Biopharma
Faculty, Medical
Improving Faculty's Ability to Speak Up to Others in the Operating Room
Importance Team members speaking-up by raising concerns about inappropriate or unsafe actions of others within the team can have direct, immediate, and preventive effect on adverse outcomes.
- Trial name
- NCT02170818
- Testing
- Educational Workshop on Speaking-Up, Unrelated Education (CPR)
- Where
- United States
- Volunteers
- 310 people
- Sponsor
- Massachusetts General Hospital
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