Clinical trials: Randomized-controlled Trial
Lumbar Intervertebral Disc Herniation
A Randomized Trial of Annular Repair With Discectomy Versus Discectomy Alone for Lumbar Disc Herniation
The goal of this study is to explore the indications and application scope of spinal endoscopy combined with annulus fibrosus repair technology, with a focus on verifying the effectiveness of annulus fibrosus suture technology…
- Trial name
- NCT07250581
- Testing
- Repair of the annulus fibrosus
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Prematurity, Respiratory Distress Syndrome
Trial of Non Invasive Ventilation for Respiratoy Distress Syndrome
The purpose of this study is to evaluate the hypothesis that nasal intermittent positive pressure(NIPP), used as a primary mode of ventilation in preterm infants with RDS, will decrease the need for conventional endotracheal…
- Trial name
- NCT00821119
- Testing
- nasal intermittent positive pressure ventilation
- Where
- 2 sites in Brazil
- Volunteers
- 200 people
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Ultrasonography, Interventional, Peripheral Venous Catheterization
Comparing Ultrasound Guided PICC Line Insertion in Neonates With Standard Procedure
This is a randomized controlled study comparing US guided vs standard procedure for PICC line placement in newborns admitted to Children's Hospital of Eastern Ontario Neonatal Intensive Care Unit who require a PICC line.
- Trial name
- NCT02584530
- Testing
- Ultrasound guidance for PICC line placement
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Children's Hospital of Eastern Ontario
Gingival Recession
Effect of Low-Level Laser on Pain and Healing of Donor Site Following Free Gingival Graft
The aim of this randomized split-mouth design clinical trial is to clinically evaluate the effectiveness of diode laser in the healing of donor site of palate in free gingival graft.
- Trial name
- NCT02896283
- Testing
- Low-level laser therapy, Turned-off laser
- Where
- Iran
- Volunteers
- 12 people
- Sponsor
- Tehran University of Medical Sciences
Local Anesthesia Injection Pain
Effectiveness of Laser Photobiomodulation Therapy in Reducing Child Pain During Local Anesthesia Injection
This study aimed to evaluate the impact of laser photobiomodulation therapy used as pre-anesthetic technique to reduce child pain during local anesthesia administration
- Trial name
- NCT05861154
- Testing
- Photobiomodulation, Benzocaine Gel
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Aliaa Hamouda
Type 2 Diabetes Mellitus
Lifestyle Therapy for Youth With Type 2 Diabetes
Background: Little is known about the efficacy of intensive lifestyle therapy (i.e. increased physical activity and dietary changes) for the management of glycemia and cardiometabolic risk factors in children and adolescents with…
- Trial name
- BDT (NCT01597154)
- Testing
- Lifestyle Counselling
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of Manitoba
Obesity, Overweight and Obesity
Solution Focused Approach in Adolescents (SFA)
Aims-objectives: This study assessed the effect of the Solution Focused Approach (SFA) interview technique on overweight/obese adolescents' nutrition-exercise attitudes and behaviors.
- Conditions
- Obesity, Overweight and Obesity, Adolescent Obesity
- Trial name
- SFA (NCT03364205)
- Testing
- solution-focused interview technique
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Peanut Allergy
Pinpoint Trial: Prebiotics IN Peanut Oral ImmunoTherapy
The purpose of this research is to gather information on the safety and efficacy of using a prebiotic as an adjunctive therapy to peanut oral immunotherapy.
- Trial name
- NCT05138757
- Testing
- Prebiotic
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Chicago
Diabetes, Hypertension
Pharmacy Interventions to Improve Chronic Disease Medication Refill
Compare the effectiveness of 3 strategies by pharmacists to decrease the time to refill of prescriptions for common chronic diseases (diabetes, hypertension, hyperlipidemia, heart failure, depression, psychoses).
- Conditions
- Diabetes, Hypertension, Hyperlipidemia, Heart Diseases
- Trial name
- NCT00469365
- Testing
- pharmacist contact with the patient via telephone, Pharmacist contact with the patient's physician via fax, Usual care
- Where
- United States
- Volunteers
- 3,048 people
- Sponsor
- Medical University of South Carolina
Malocclusion, Angle Class II
Effect of Low-Intensity Pulsed Ultrasound on Functional Treatment of Class II Malocclusion
This experimental study will evaluate the effect of combined treatment with low-intensity pulsed ultrasound (LIPUS) and functional appliances (twin-block) on the correction of class II malocclusion, compared with the control…
- Trial name
- NCT03251807
- Testing
- Twin-block, LIPUS (Low-intensity pulsed ultrasound)
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Stomach Neoplasm
Treatment Strategy for Stage IV Gastric Cancer with Positive Peritoneal Cytology As the Only Non-curable Factor
Gastric cancer with positive is defined as stage IV disease in 7th AJCC/UICC TNM staging system. Controversy exists on the treatment of this part of patients.
- Trial name
- Cy-plus (NCT02969122)
- Testing
- standard gastrectomy with D2 lymphadenectomy, hyperthermic intraperitoneal chemotherapy, Extensive intraperitoneal lavage
- Where
- China
- Volunteers
- 59 people
- Sponsor
- Peking University
Childhood Lymphoblastic Lymphoma
Evaluation of Therapeutic Video Games for Pre-school Children With Acute Lymphoblastic Leukemia
The purpose of this study is to evaluate the effectiveness of therapeutic video game.
- Trial name
- NCT04199637
- Testing
- TVG
- Where
- Taiwan
- Volunteers
- 15 people
- Sponsor
- National Yang Ming Chiao Tung University
Mycobacterium Ulcerans Infection
WHO Drug Study for Buruli Ulcer - Comparison of SR8 and CR8
This is a WHO-sponsored trial. Combination therapy with streptomycin and rifampicin has been the standard antibiotic treatment for M. ulcerans infection since 2004.
- Trial name
- NCT01659437
- Testing
- Clarithromycin Extended Release, Streptomycin intramuscular injection
- Where
- 5 sites in Benin, Ghana
- Volunteers
- 310 people
- Sponsor
- University Medical Center Groningen
Treatment 1:Dialectical Behavior Therapy (DBT), Treatment as Usual
Efficacy of "DBT-LIVE", an Identity Skills Training Program, for Borderline Personality Disorder.
The main objective of this project is to adapt and evaluate the LIVE Skill module in the Spanish population. LIVE Skill is a psychological intervention protocol specifically designed to address identity disturbances in…
- Trial name
- NCT07684872
- Testing
- DBT LIVE, TAU
- Where
- Spain
- Volunteers
- 112 people
- Sponsor
- Universidad Europea de Valencia
Child, Sleep
Effectiveness of the Sleep Island WeChat Mini-Program for Promoting Sleep in Preschool Children
Behavioral sleep problems are common during the preschool years and are strongly influenced by parental sleep-related practices and the home environment.
- Conditions
- Child, Sleep, Promotion, Digital Intervention
- Trial name
- Sleep Island (NCT07792577)
- Testing
- Sleep Island (安睡岛) Digital Behavioral Sleep Promotion Program
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Autism Spectrum Disorder
Integrated Life Skill Training and Executive Function Strategies in Children With ASD
The goal of this clinical trial is to test if using what is called executive function strategies like strategies for improving self-regulation ,strategies for improving planning and problem solving work well when applied within…
- Trial name
- ASD (NCT05829577)
- Testing
- Executive Function Strategies and Training, Daily Life skill training, Sensory Integration /Processing training
- Where
- Qatar
- Volunteers
- 92 people
- Sponsor
- Hamad General Hospital
Microstomia, Systemic Sclerosis
The Effect of a Home-based Orofacial Exercise Program on Oral Aperture of Systemic Sclerosis Patients
Systemic sclerosis is a systemic disease which may involve multiple organ systems and cause functional disabilities. Microstomia is one of the most common complications of the disease which may result in difficulties performing…
- Trial name
- NCT04336475
- Testing
- orofacial exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cukurova University
Neck Pain
Evaluation of Pain Quality in Young Swimmers Suffering From Myofascial Pain Syndrome Using Lidocaine Phonophoresis
To evaluate pain quality by pain quality assessment scale (PQAS) using lidocaine phonophoresis on myofascial pain syndrome (MPS) in athletic children.
- Trial name
- MPS (NCT06573775)
- Testing
- pulsed ultrasound, myofascial release, lidocaine phonophoresis
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- New Ismailia National University
Cerebral Palsy, Prematurity
Best Practices Fo Early Diagnosis of Cerebral Palsy
In this research, the investigators are using an implementation science approach to enhance the uptake of a clinical practice guideline for earlier diagnosis of cerebral palsy (i.e.
- Trial name
- CP (NCT06537622)
- Testing
- Implementation group, Standard of care
- Where
- Canada
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Rabies
A Clinical Trial of Rabies Vaccine（Human Diploid Cell）for Human Use,Freeze-dried in a Population Aged 10 to 60 Years
A total of 3,000 participants will be enrolled, stratified by age into two groups: 600 participants aged 10-17 years and 2,400 participants aged 18-60 years.
- Trial name
- NCT07275645
- Testing
- Rabies Vaccine（Human Diploid Cell）for Human Use,Freeze-dried
- Where
- 5 sites in China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Ab&B Bio-tech Co., Ltd.JS
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