Clinical trials: Reconstructive Surgical Procedure
Unilateral Cleft Lip
Philtrum Reconstruction Using Autogenous Fat Injection Versus a Surgical Repair in Secondary Unilateral Cleft Lip Revision
Two groups of patients with repaired unilateral cleft lip deformity having mild to moderate grooving and/or scarring of the philtral column and requiring a secondary cleft lip repair.
- Trial name
- NCT04735237
- Testing
- Autogenous fat injection, Surgical revision with orbicularis oris muscle reconstruction.
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
ACL Injury
Continuous Vs Single Shot Block After ACL
The investigators will be randomizing patients to either receive an adductor canal block in the operating room postoperatively as single shot of 20-30cc bupivacaine or to have a catheter inserted into the adductor canal which…
- Trial name
- NCT04101682
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Patellofemoral Dislocation
Patellar Stability After MPFL Reconstruction With Fascia Lata Allograft: Conventional CT vs Under Weight-bearing CT
The objective of the present study is to compare the stability and alignment of the patella in patients with previous recurrent dislocation treated with medial patellar femoral ligament reconstruction with fascia lata allograft…
- Trial name
- NCT04242732
- Testing
- CT scan of the knee under weight-bearing with the Cone Beam Computed Tomography (CBCT) scanner system., Conventional CT scan
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Ortopedico Rizzoli
Post Traumatic Soft Tissue Defects That Could be Reached by Pedicled Anterolateral Thigh Flap, Post Tumor Excision Soft Tissue Defects
Reliability and Versatility of Pedicled Anterolateral Thigh Flap in Reconstruction of Soft Tissue Defects
a prospective case series study for evaluation of the reliability and versatility of pedicled anterolateral thigh flap in the reconstruction of soft tissue defects as regards flap survival and complications, donor site morbidity…
- Conditions
- Post Traumatic Soft Tissue Defects That Could be Reached by Pedicled Anterolateral Thigh Flap, Post Tumor Excision Soft Tissue Defects, Post Debridement Soft Tissue Defects
- Trial name
- NCT06841419
- Testing
- surgical reconstruction of a soft tissue defects by a pedicled flap
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Anterior Cruciate Ligament Reconstruction Rehabilitation
ACL Reconstruction Rehabilitation With Exercise and Psychological Support
The purpose of this study is to examine ACLR Rehabilitation with Exercise and Psychological Support (REPS), comparing two approaches for providing psychological support along with exercise during ACL reconstruction…
- Trial name
- ACLR-REPS (NCT06991192)
- Testing
- Rehabilitation with Exercise and Psychological Support (REPS)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- HealthPartners Institute
Mandibular Injuries
Accuracy and Outcome of Computer-assisted Surgery for Bony Micro-vascular Reconstruction in the Head and Neck Region
Background: Functional and aesthetic reconstruction of mandibular defects due to tumour invasion, osteoradio- or chemonecrosis or trauma are challenging.
- Trial name
- NCT03054012
- Volunteers
- 30 people
- Sponsor
- AZ Sint-Jan AV
Orbital Bone Fracture, Maxillary Cyst
Application of CAD-CAM Technology in Orbital Bone Reconstruction
Reconstruction of orbital defects resulting after trauma; tumor resection; maxillary cyst; craniofacial anomalies and sequestrated bone….
- Conditions
- Orbital Bone Fracture, Maxillary Cyst, Maxillary Neoplasms, Zygomatic Fractures
- Trial name
- CAD-CAM (NCT05438784)
- Testing
- orbital bone reconstruction with patient specific titanium implant, orbital bone reconstruction with preformed titanium plate preoperatively bended on stereolithographic model
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Hatem Adel Aboelhassan
Brachial Plexus Injury
Enhancing Functional Hand Recovery Through Nerve Reconstruction in Total Brachial Plexus Birth Injury
Interpreting the published outcomes of hand function in total BPBI is confounded by a lack of clear documentation regarding detailed surgical findings and management strategies.
- Trial name
- NCT06313658
- Testing
- Total brachial plexus exploration and reconstruction
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Bone Facial Bone
Delayed Secondary Reconstruction of Alveolar Clefts Using Autogenous Symphyseal Particulate Bone Versus Iliac Cancellous Bone: A Randomized Clinical Trial
Patients with alveolar clefts whose ages are after 12 years (after eruption of all permanent dentition) were recruited and treated either by particulate bone grafting from the symphysis or from the anterior iliac crest
- Trial name
- NCT06455176
- Testing
- alveolar cleft Grafting from the symphysis, alveolar cleft Grafting from the iliac cancellous bone
- Volunteers
- 20 people
- Sponsor
- Cairo University
Upper Extremity Defects
Reconstruction of Hand and Upper Extremities Defects by Thin Random Pedicle Abdominal Flaps, Still a Valid Option in Developing Countries: A Cross Sectional Study
Traumatic defects of the soft tissues of the hand and upper extremities are common and may be challenging to the reconstructive surgeon.
- Trial name
- NCT04007497
- Where
- Jordan
- Volunteers
- 34 people
- Sponsor
- University of Jordan
Alveolar Cleft Operated on an Alveolar Bone Graft
Alveolar Bone Graft Cortical Nasal Floor
Alveolar bone graft is one of the main step of the surgical care of the patients who are suffering from cleft lip and palate. They are usually performed before the lateral incisor eruption, at about 5 years old and using…
- Trial name
- NCT03883373
- Testing
- alveolar bone graft with cancellous bone and a cortical block, alveolar bone graft with cancellous bone only
- Where
- France
- Volunteers
- 302 people
- Sponsor
- University Hospital, Montpellier
Anterior Cruciate Ligament Reconstruction
Operation ACL: Rehabilitation After Anterior Cruciate Ligament Reconstruction
Scientific Research Question Overall Purpose: Regarding rehabilitation after anterior cruciate ligament reconstruction (ACLR), there is a knowledge gap - a lack of evidence.
- Trial name
- NCT06318039
- Testing
- Novel program, Traditional program
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Linnaeus University
Autografts, Blood Flow Restriction Therapy
Blood Flow Restriction Following ACLR w/Quad Autograft
This project is intended to acquire objective measurements of implementing BFR rehabilitation in ACL reconstructions to show any changes upon completion of the BFR protocol.
- Conditions
- Autografts, Blood Flow Restriction Therapy, Rehabilitation Outcome, Quadriceps Muscle Strength
- Trial name
- BFR Quad Delay (NCT06636045)
- Testing
- Not applicable- observational study
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Kansas Medical Center
Maxillary Defect Reconstruction
Manual Dexterity of Patients With Bilateral Complete Maxillectomy Rehabilitated by Different Approaches (A Cross-over Study)
10 participants received 2 piece obturators connected with magnet attachment, after 3 months the magnets were replaced by dowel pins and given to the participants for a further 3 months.
- Trial name
- NCT07756983
- Testing
- Dowel Pin
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- October University for Modern Sciences and Arts
Finger Tip Amputations
The Use of Composite Bone and Nail Bed Graft Combined With Cutaneous Flaps for Reconstruction of Finger Tip Amputations
Fingertip injuries are among the most common hand injuries regardless of age, as the fingertip is a prominent and frequently used part of the hand.
- Trial name
- NCT05961891
- Testing
- The Use of Composite Bone and Nail Bed Graft Combined With Cutaneous Flaps for Reconstruction of Finger Tip Amputations
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Post-operational Pain
A Randomized, Double Blind, Placebo-controlled Study to Assess the the Preemptive Benefit of Etoricoxib in Patients Receiving Anterior Cruciate Ligament Reconstruction
Post surgical pain associated with ligament reconstruction may persist for few days after the surgical procedure. Arcoxia is a new anti-inflammatory and analgesic drug that alleviate pain through oral administration.
- Trial name
- NCT00554346
- Testing
- Arcoxia(etoricoxib 90 mg/tablet)
- Where
- Taiwan
- Volunteers
- 64 people
- Sponsor
- National Taiwan University Hospital
Alveolar Cleft
Bilateral Alveolar Cleft Reconstruction Using Double Iliac Bone Blocks vs Particulate Grafting
This study aims to compare the clinical outcomes of bilateral alveolar cleft reconstruction using double iliac corticocancellous bone block grafts versus conventional autogenous particulate bone grafting.
- Trial name
- NCT07442279
- Testing
- Iliac Corticocancellous Bone Block Graft, Autogenous Particulate Bone Graft
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Anterior Cruciate Ligament Reconstruction
Pediatric ACL: Understanding Treatment Options
Pediatric ACL: Understanding Treatment Outcomes (PLUTO) is a multi-center, prospective cohort study. Specific aims of PLUTO are to evaluate the safety and comparative effectiveness of non-operative treatment, as well as four…
- Trial name
- PLUTO (NCT02772770)
- Testing
- Non-operative treatment group will undergo standardized treatment which will include rehabilitation, bracing and certain activity restrictions, Surgical technique: Transphyseal reconstruction, Surgical technique: Partial transphyseal reconstruction
- Where
- 10 sites in United States
- Volunteers
- 765 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Anterior Cruciate Ligament Reconstruction
Study of RNS60 on Pain and Function After Knee Anterior Cruciate Ligament Surgery
The purpose of this study is to see if use of RNS60 during ACL reconstruction surgery decreases pain and improves functional capacity post-operation.
- Trial name
- NCT01922427
- Testing
- RNS60
- Sponsor
- Revalesio Corporation
ACL Injury, Post Operative Pain
iPACK for Post-op Pain Following ACL Reconstruction
This study will consist of patients 12 years and older undergoing ACL reconstruction using a quadriceps or bone-patella tendon bone (BTB) graft.
- Trial name
- NCT05498870
- Testing
- Adductor Canal Block (ACB) Only, Adductor Canal Block (ACB) + iPACK Block
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Medical University of South Carolina