Clinical trials: Refractive Disorders
Myopia, Progressive
Myopia Prevention Through Monitoring and Motivating Outdoor Activities With Smartwatches
The goal of this multi-center, randomized, parallel-controlled clinical trial is to evaluate the effectiveness of outdoor activities monitoring and motivating by smartwatches to prevent myopia progression in children.
- Trial name
- NCT05760911
- Testing
- Outdoor activities motivation with smartwatches
- Volunteers
- 1,200 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Visual Acuity, Astigmatism
LFR-260 vs Traditional Phoropter in Visual Acuity Testing
The purpose of this study is to establish if LFR-260 (investigational device) is not inferior in effectiveness to a traditional phoropter (control device) when applied in visual acuity test in subjects undergoing a full routine…
- Conditions
- Visual Acuity, Astigmatism, Anisometropia
- Trial name
- NCT05259163
- Testing
- LFR-260 portable phoropter, Traditional phoropter (SOC)
- Where
- 2 sites in United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Evolution Optiks Limited
Myopia
Clinical Evaluation of a Silicone Hydrogel Lens
The purpose of this study is to assess the performance of an investigational contact lens among contact lens wearers.
- Trial name
- NCT01016132
- Testing
- lotrafilcon A contact lens
- Volunteers
- 152 people
- Sponsor
- CIBA VISION
Myopia, Pre-myopia
Virtual Far-sight Reading Device for Myopia Intervention Among Pre-myopic Children
This clinical trial wants to find out if the Virtual Far-sight Reading Device can help prevent or slow down myopia progression in children and teenagers with pre-myopia.
- Trial name
- NCT06995911
- Testing
- Virtual Far-sight Reading Device
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
Impact of Electronic Devices on Myopia Development and Progression
The aim of the stuy is to investigate the effects of the adoption of a curriculum with electronic devices for teaching materials and textbooks in Hong Kong schoolchildren on their changes in refractive error and visual function.
- Trial name
- NCT02150421
- Where
- China
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia
The Evaluation of Safety and Myopia Progression Control Using Novel Spectacle Lens
The goal of this clinical trial is to test Novel spectacle lenses in myopic children. The main question it aims to answer are: safety and efficacy of the lenses.
- Trial name
- NCT05886348
- Testing
- Model-A Novel spectacle lens, Model-B Novel spectacle lens, Single vision spectacle lens
- Where
- 5 sites in China
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- HOYA Lens Thailand LTD.
Myopia
Using Contact Lenses and Spectacle Lenses as Myopia Interventions.
Effect of alternating contact lenses and spectacles for myopia control.
- Trial name
- NCT07845721
- Testing
- Test Spectacle Lens & Contact Lens, Control Spectacle Lens & Contact Lens
- Where
- 2 sites in Canada, United Kingdom
- Volunteers
- 58 people
- Sponsor
- CooperVision International Limited (CVIL)
Amblyopia, Refractive Errors
Vision Screening for the Detection of Amblyopia
INTRODUCTION. Amblyopia is defined as the loss of visual acuity (VA) in one or both eyes, without any obvious structural or pathological anomalies.
- Conditions
- Amblyopia, Refractive Errors, Anisometropia, Strabismus
- Trial name
- NCT01430247
- Testing
- Amblyopia screening
- Where
- Croatia
- Volunteers
- 7,000 people
- Sponsor
- Mladen Busic
Myopia
Visual Performance of Center Distance Daily Disposable Multifocal Lenses
The purpose of this study is to compare visual performance (high and low contrast acuity, reading acuity, contrast sensitivity, stereoacuity, accommodative response, eye hand coordination, far near vision, and dynamic vision)…
- Trial name
- ViPCD3 (NCT06475053)
- Testing
- NaturalVue Enhanced Multifocal 1 Day contact lens, MiSight 1 Day contact lens
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Visioneering Technologies, Inc
Near Vision, Refractive Error Correction
Clinical Outcomes of the Use of a Femtosecond Laser Treatment in a Patient With Implanted Monofocal IOLs
This study aims to assess the safety and efficacy of evaluating near vision or refractive error in eyes implanted with a mono focal intraocular lens (IOL) using a low-energy femtosecond laser.
- Trial name
- NCT07447622
- Testing
- Device
- Where
- Czechia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Perfect Lens, LLC
Nearsightedness, Farsightedness
Advanced Surface Ablation (ASA) vs Laser-Assisted In Situ Keratomileusis (LASIK)
The purpose of this combined retrospective and prospective chart review analysis is to investigate the safety, efficacy, and predictability obtained via Laser-Assisted In Situ Keratomileusis (LASIK) and Advanced Surface Ablation…
- Conditions
- Nearsightedness, Farsightedness, Astigmatism
- Trial name
- NCT00778570
- Where
- Canada
- Volunteers
- 4,000 people
- Sponsor
- Ottawa Hospital Research Institute
Refractive Errors
Post-market Clinical Follow-up Study of Alcon PRECISION1™ Spherical and PRECISION1™ for Astigmatism Soft Contact Lenses
The purpose of this study is to assess long term performance and safety of verofilcon A soft contact lenses in a real-world setting in a population of 7 years or older having at least 1 year of verofilcon A (sphere or toric)…
- Trial name
- NCT06462456
- Testing
- Verofilcon A spherical soft contact lenses, Verofilcon A toric soft contact lenses
- Where
- 12 sites in United States
- Volunteers
- 140 people
- Sponsor
- Alcon Research
Myopia
A Comparison of AIR OPTIX® COLORS Versus FRESHLOOK® COLORBLENDS
The purpose of this study was to evaluate the overall comfort of AIR OPTIX® COLORS compared to FRESHLOOK® COLORBLENDS in habitual wearers of the FRESHLOOK® COLORBLENDS .
- Trial name
- NCT01635933
- Testing
- Lotrafilcon B contact lens with color, Phemfilcon A contact lens with color
- Volunteers
- 370 people
- Sponsor
- Alcon Research
Myopia
Tolerability of a Novel Spectacle Design With Reduced Peripheral Contrast
Prospective, randomized, subject-masked 3-arm clinical study to assess the pediatric acceptability across three iterations of a novel spectacle lens design.
- Trial name
- WALNUT (NCT03761758)
- Testing
- Spectacle lenses
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Myopia
An Evaluation of the Effectiveness of Dual Focus Soft Contact Lenses in Slowing Mypoia Progression
The purpose of this study is to determine whether a new type of soft contact lens with a unique optical design (dual focus) is effective at slowing the progression of myopia (near-sightedness) in children.
- Trial name
- NCT01729208
- Testing
- Dual Focus Soft Contact Lens, Single Vision Soft Contact Lens
- Where
- 4 sites in Canada, Portugal and 2 more
- Volunteers
- 144 people
- Sponsor
- CooperVision, Inc.
Myopia
Efficacy and Influencing Factors of Repeated Low-level Red-light in Myopia
To evaluate the long-term efficacy of repeated low-level red-light (RLRL) therapy in the prevention and control of myopia in children, and to analyze the key factors influencing its efficacy (such as individual differences and…
- Trial name
- RLRL (NCT07104513)
- Testing
- Red Light
- Where
- 2 sites in China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Ruihua Wei
Myopia, Progressive, Children, Only
Long-term Efficacy of Orthokeratology Contact Lens Wear in Controlling the Progression of Childhood Myopia
To assess the long-term efficacy of the Menicon Z Night orthokeratology contact lens in controlling the progression of childhood myopia
- Trial name
- MCOS7 (NCT04806698)
- Testing
- Menicon Z Night, Control
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Menicon Co., Ltd.
Myopia, Myopia Progression
The P.A.U.S.E.® Spectacle Study
The goal of this clinical trial is to learn if spectacle lenses using Phase Alteration Utilising Sub Elements (P.A.U.S.E.®) technology works to slow down the rate of myopia progression in myopic children.
- Trial name
- NCT06577948
- Testing
- Single vision spectacle lens, P.A.U.S.E. spectacle lens 1, P.A.U.S.E. spectacle lens 2
- Where
- Vietnam
- Volunteers
- 205 people
- Sponsor
- nthalmic Pty Ltd
Myopia, Hyperopia
Bilateral Dispensing Study of Fanfilcon A Toric Versus Enfilcon A Toric Lenses
Bilateral dispensing clinical trial of fanfilcon A toric lens verses enfilcon A toric lens over two weeks.
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- NCT02423109
- Testing
- fanfilcon A, enfilcon A
- Where
- 2 sites in United States, Canada
- Volunteers
- 44 people
- Sponsor
- CooperVision, Inc.
Myopia, Progressive
Near Horizontal Heterophoria in Chinese Children
This study aimed to assess the association of refraction and axial length with near-horizontal heterophoria in a large population-based study of school-aged Chinese children.
- Trial name
- NCT05007626
- Testing
- axial length and refractive error
- Where
- China
- Volunteers
- 15,081 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital