Clinical trials: Refractive Error
Myopia
A 3-year Cross-sectional Assessment of the Tianjin Child and Adolescent Large-scale Eye Study
This is a school-based, cross-sectional study to assess the incidence and prevalence, risk factors of myopia among schoolchildren in both eye-use environment, eye-use habits, lifestyle, and family and subjective factors before…
- Trial name
- NCT05967702
- Where
- China
- Volunteers
- 126,810 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Refractive Assessment, Refractive Disorders
Algorithm-assisted Subjective Refraction Program Dedicated to Children
Current refraction assessment in children is dependent on the Eye Care Specialist and lacks standardization. Essilor has developed new algorithm assisted subjective refraction software dedicated to children of 6-12 years old and…
- Conditions
- Refractive Assessment, Refractive Disorders, Hyperopia and Myopia, Astigmatism
- Trial name
- NCT07046065
- Testing
- Non-cycloplegic Objective refraction, Non-cycloplegic conventional subjective refraction, Non-cycloplegic subjective refraction (Kids refraction software vA with Vision-R™)
- Where
- Portugal
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia, Myopia Progression
Myopia Control Spectacle Lens Cessation Study
To quantify myopic progression (cycloplegic spherical equivalent refraction - cSER) following the cessation of use of specific spectacle lenses.
- Conditions
- Myopia, Myopia Progression, Juvenile Myopia
- Trial name
- BIRCH (NCT05893979)
- Testing
- Spectacle Lenses
- Where
- 8 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Myopia
Myopia Prevention With Reading Glasses
The last decades have seen a significant increase in myopia in children and young adults. Possible cause: increased near-work (school, computer, smartphone).
- Trial name
- SMART2 (NCT05030103)
- Testing
- Reading glasses, +2.0 diopters
- Where
- Liechtenstein
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Reis Augenklinik AG
Myopia
The Collaborative Longitudinal Evaluation of Ethnicity and Refractive Error (CLEERE) Study
To compare and contrast normal eye growth, ocular component development, and refractive error development in Hispanic, African-American, and Asian schoolchildren with what happens in Caucasian children from the Orinda…
- Trial name
- NCT00000169
- Where
- 3 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Myopia
A Clinical Study to Evaluate the Remote Monitoring of Myopia Patients With the EyeQue Insight
The objective of this study is to determine whether the remote monitoring of myopia patients with the EyeQue Insight (visual acuity test) can replace regularly scheduled follow-up visits.
- Trial name
- NCT04693260
- Testing
- Visual Acuity with a Hand-held Device Supported by Mobile App.
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- EyeQue Corp.
Myopia, Astigmatism
An Outcomes Study Comparing the Intralase FS 60 to the Intralase iFS When Performing LASIK Surgery for Nearsightedness
The purpose of the study is to compare the results of LASIK surgery when using two versions of a femtosecond laser in patients with nearsightedness with and without astigmatism.
- Trial name
- NCT01365728
- Testing
- LASIK with the iFS femtosecond laser
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Stanford University
Myopia
Effect of Using Myopia Prediction Algorithm on Myopia School-aged Children
In this study, the investigators aim to perform a prospective, randomized controlled study to compare the myopia development between myopia children using myopia prediction algorithm and myopia children without using myopia…
- Trial name
- NCT04045951
- Testing
- Myopia prediction algorithm
- Where
- China
- Volunteers
- 2,138 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Presbyopia
Safety and Efficacy of an Intrastromal Transform™ Corneal Allograft (TCA) for Presbyopia Correction
The objective of this clinical study is to evaluate the safety and effectiveness of intrastromal implantation of the Allotex TransForm corneal allograft (TCA) for improving near vision in presbyopic subjects.
- Trial name
- NCT03671135
- Testing
- TCA Intrastromal Inlay
- Where
- 4 sites in Belgium, Ireland and 1 more
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Allotex, Inc.
Myopia, Progressive
A Unified Index to Predict the Success Probability of Myopia Control
Orthokeratology lenses (OK-lens) and multifocal contact lenses (MFCL) are optical devices designed to slow down the progression of myopia. Both treatments a long-term commitment from doctors and patients.
- Trial name
- NCT05773118
- Testing
- orthokeratology lens, multifocal soft contact lens, Single vision spectacles
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Retinopathy of Prematurity, Myopia
Prematurity and Ophthalmological Changes
Ophthalmological differences in school-aged children with and without a history of retinopathy of prematurity
- Trial name
- NCT06452524
- Testing
- axial length (AU) and anterior chamber depth (ACD), optical coherence tomography (OCT)
- Where
- Turkey (Türkiye)
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Pathological Myopia
Genomewide Screening of Pathological Myopia
The purpose of this study is to evaluate the possible candidate gene of pathological myopia
- Trial name
- NCT00155753
- Where
- Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Myopia, Dental Caries
Bedtime Routines and Children's Health
In Taiwan, the prevalence of sleep problems, myopia, and dental caries in school-age children is high. Little is known regarding the implementation of oral and vision health outcomes around bedtime.
- Conditions
- Myopia, Dental Caries, Sleep, Asthenopia
- Trial name
- NCT05201924
- Testing
- Bedtime routine, Control
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Taiwan University
Myopia
Myopia Prevalence in Canadian School Children - a Pilot Study
The goal of this study is to determine the prevalence of nearsightedness in Canadian school children living in the Waterloo Region.
- Trial name
- Falcon (NCT01942057)
- Where
- Canada
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Myopia, Light; Therapy, Complications
Optimizing Light Exposure for Myopia Prevention and Control (LightSPAN)
The goal of this clinical trial is to evaluate whether the optimization of daily exposure to light in primary school children can lead to better myopia prevention and control.
- Conditions
- Myopia, Light; Therapy, Complications, Myopia Progression, Short-Sighted
- Trial name
- LightSPAN (NCT06631339)
- Testing
- Light Intervention, Digital Intervention, Control Group
- Where
- 5 sites in Singapore
- Volunteers
- 396 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Myopia
SEED-LVPEI Myopia Study
This randomized clinical trial study aims to investigate the efficacy of novel SEED's EDOF based mid-lens design in controlling the myopia progression in Indian children with these specific objectives: 1.
- Trial name
- SLIMS (NCT04618510)
- Testing
- SEED 1-dayPure EDOF soft contact lens, Single Vision Spectacles
- Where
- India
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- L.V. Prasad Eye Institute
Myopia
The Role of SNP of ECM and MMP on the Development of Pathological High Myopia
To study the clinical characteristics and inheritance of pathological myopia in Taiwanese patients.
- Trial name
- NCT00172952
- Where
- Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Myopia, Astigmatism
Toric Orthokeratology - Slowing Eye Elongation
The aims of this study are to investigate the effects of ortho-k for astigmatic and myopic reduction and myopic control in children, and the long term effects on corneal curvatures and biomechanics.
- Trial name
- TO-SEE (NCT00978692)
- Testing
- Toric Orthokeratology lenses, Single-vision spectacles
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Amblyopia, Anisometropia
Enhanced Housing Photoscreeners 2WIN and GoCheckKids Compared in Burma and Alaska
"Adaptica" (Padova, Italy) designed a fixed-distance, dark portable tube with power and remote control for the "2WIN: photoscreener.
- Trial name
- NCT04068129
- Testing
- photoscreen
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Alaska Blind Child Discovery
Myopia, Quality of Life
Functional Vision and Quality of Life in a Modern Society - With Emphasis on Myopia and Cerebral Visual Impairment Among Youth
Society has become increasingly digital, and many everyday services have been replaced by digital self-service solutions. This puts greater demands on our vision and our ability to interpret what we see.
- Trial name
- NCT07653074
- Testing
- ophthalmological examination
- Where
- Sweden
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Region Örebro County