Clinical trials: Regional Block
Anesthesia, Local
Ropivacaine Plasma Concentrations and Pharmacokinetics Following Erector Spinae Plane Block in the Pediatric Population
The primary aim of this study is to evaluate the pharmacokinetics of serum ropivacaine concentrations following erector spinae plane peripheral nerve blocks in the pediatric population.
- Trial name
- NCT04298099
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Baylor College of Medicine
Opioid Use, Post-thoracotomy Pain Syndrome
Serratus Anterior Plane Block for Management of Post Thoracotomy Pain
This is a single-center, randomized, prospective study evaluating the effect of serratus anterior plane block performed after induction of anesthesia, but before the start of surgery on postoperative opioid requirements.
- Conditions
- Opioid Use, Post-thoracotomy Pain Syndrome, Local Anaesthetic Agent Overdose, Local Anesthetic Complication
- Trial name
- SAPB (NCT04258436)
- Testing
- Serratus anterior block
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Indiana University
Cholecystitis, Appendicitis
Ultrasound Guided Rectus Sheath Block and Transversus Abdominis Plane Block
The current study aimed to assess the efficacy of Dexmedetomidine (DEX) and Dexamethasone as an adjuvant to ultrasound guided TAP and RS block to prolongation of postoperative analgesia and better pain control in children…
- Trial name
- NCT04838379
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Inguinal or Ovarian Hernia, Hydrocele
Transversus Abdominis Plane Block in Pediatrics: Volume or Concentration ?
The transversus abdominis plane (TAP) block provide a local anesthesia drug diffusion between the transverse abdominis muscle and the internal oblique muscle.
- Conditions
- Inguinal or Ovarian Hernia, Hydrocele, Cord Kyst, Local Analgesia Block
- Trial name
- TAP Bloc (NCT02064088)
- Testing
- Injection of 0,2 ml/kg of 0,2% levobupivacaine for small volume group, Injection of 0,4 ml/kg of 0,1% lévobupivacaine for high volume group
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Montpellier
Postoperative Pain, Tonsillectomy
Sphenopalatine Ganglion Block for Pain Relief After Pediatric Adenotonsillectomy
The aim of this clinical trial is to discover whether sphenopalatine ganglion block (SPGB) reduces postoperative pain in children aged 2 to 13 years undergoing tonsil surgery (with or without adenoid removal).
- Conditions
- Postoperative Pain, Tonsillectomy, Adenotonsillectomy
- Trial name
- SPARK (NCT07793617)
- Testing
- Sphenopalatine ganglion block (Ropivacaine)
- Volunteers
- 145 people
- Sponsor
- Vinícius C Quintão, MD, MSc, PhD
Postoperative Pain, Pediatric Surgery
Caudal Epidural Vs. TAP Block for Postoperative Analgesia in Pediatric Infraumbilical Surgery: a RCT
This randomized controlled trial investigates the postoperative analgesic efficacy of caudal epidural block versus ultrasound-guided transversus abdominis plane (TAP) block in pediatric patients undergoing infraumbilical surgery.
- Conditions
- Postoperative Pain, Pediatric Surgery, Anesthesia, Local, Regional Anesthesia
- Trial name
- NCT06895382
- Testing
- Caudal Epidural Block, Transversus Abdominis Plane (TAP) Block, Bupivacaine 0.25%
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Namik Kemal University
Sacral Erector Spinae Plane Block, Pediatric Regional Anesthesia
Sacral Erector Spinae Plane Block Versus Penile Block For Analgesia In Pediatric Circumcision
Circumcision is one of the most frequently performed surgical procedures in childhood and is associated with significant postoperative pain.
- Conditions
- Sacral Erector Spinae Plane Block, Pediatric Regional Anesthesia, Regional Anaesthesia
- Trial name
- NCT07321717
- Testing
- Sacral Erector Spinae Plane Block, Penile Nerve Block (PNB)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Blood Bupivacaine Concentration
Blood Bupivacaine Concentration After Regional Block Applications in Pediatric Patients
Analgesia methods such as systemic analgesics, quadratus lumborum block, and transversus abdominis plane block are used for pain management after lower abdominal surgery.
- Trial name
- NCT07256535
- Testing
- Transversus Abdominis Plane Block, Quadratus Lumborum Block
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Kocaeli University
Anesthesia, Local
Serratus Anterior Plane Block in Pediatric Patients
The aim of this work is to study the efficacy of ultrasound guided serratus anterior plane block in pediatric patients undergoing thoracic surgeries. It is a randomized controlled trial.
- Trial name
- NCT04444635
- Testing
- Serratus Anterior Plan Block+ Fentanyl infusion, Fentanyl
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Severe Aortic Stenosis
SOURCE XT REGISTRY
This registry is to expand upon existing data sets, to identify patient characteristics and indicators related to complications and clinical benefits for patients with symptomatic severe calcific degenerative aortic stenosis that…
- Trial name
- NCT01238497
- Testing
- TAVR Implantation of the Transcatheter Aortic Valve Prosthesis
- Where
- 104 sites in Austria, Belgium and 16 more
- Volunteers
- 2,954 people
- Sponsor
- Edwards Lifesciences
Analgesia
Comparing the Efficacy of Ultrasound Guided Erector Spinae Plane Block, Ultrasound Guided Caudal Block, and Local Infiltration for Postoperative Pain Control in Pediatric Patients Undergoing Unilateral Inguinal Hernia Repair as a Day-Case Surgeries: A Randomized Controlled Trial
The aim of this study is to evaluate the efficacy of ultrasound guided Erector block versus caudal block versus local wound infiltration perioperatively according to: Primary outcome: to assess and compare the postoperative…
- Trial name
- ECLU (NCT06849804)
- Testing
- Erector Spinae (ESP) Block with Bupivacaine (Marcaine®), Caudal Block Anesthesia, Local infiltration in the wound
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Tanta University
Local Analgesia Via Infiltration, Caudal Epidural Anesthesia
Perioperative Analgesia Using Ultrasound Guided Erector Spinae Block vs Ultrasound Guided Caudal Block for Pain Control in Children Aged 2-7 Years Undergoing Lower Abdominal Surgery
The goal of this prospective study is to is to evaluate the perioperative pain management of Erector Spinae Block versus Caudal Block using the Face, Legs, Activity, Cry, Conceal ability (FLACC) Pain Scale inn children aged 2 to…
- Conditions
- Local Analgesia Via Infiltration, Caudal Epidural Anesthesia, Caudal Block, Caudal Block for Postoperative Analgesia
- Trial name
- NCT07281235
- Testing
- Ultrasound Guided Bilateral single shot Erector Spinae Plane Block, Caudal Block Anesthesia
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Ilioinguinal Nerve Block, Local Anesthesia
Comparing Ilioinguinal Single-shot and Three-layer Blocks
Ilio-inguinal nerve blocks have a long history of efficacy in treatment of post-operative pain following inguinal surgery. Several anatomic studies have shown that the nerves supplying the inguinal area have a certain degree of…
- Conditions
- Ilioinguinal Nerve Block, Local Anesthesia, Post-operative Analgesia
- Trial name
- NCT01625780
- Testing
- 3-layer block, Single-shot block
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of Alberta
Pediatric Anesthesia
Variation of Cerebral Blood Flow in Anterior Cerebral and Basilar Artery in Neonates and Infants in Genreal Anesthesia With Caudal Block
With this study we want to see how the blood flow in the anterior cerebral artery (ACA) and the basilar artery (BA) after the caudal block changes.
- Trial name
- NCT02761954
- Volunteers
- 50 people
- Sponsor
- Bürgerhospital Frankfurt
Local Anesthesia
Buffered Anesthetic Solution in the Treatment of Mandibular Primary Molars
In a prospective, randomized clinical trial, triple-blind, split-mouth study, 40 children aged between 7 to 10 with bilateral mandibular primary molars were diagnosed with pulpitis.
- Trial name
- NCT05793905
- Testing
- Buffered lidocaine in inferior alveolar nerve block injection, lidocaine 2% in inferior alveolar nerve block injection
- Where
- Syria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Damascus University
Pain, Post Operative, Regional Anesthesia
Pain Reduction in Maxillomandibular Surgery Using Maxillary and Mandibular Nerve Blocks
Maxillo-mandibular osteotomy is a painful surgery which requires mostly opioids use. Recent studies on maxillary and mandibular nerve blocks have suggested benefit in maxillo-facial surgery but have been poorly investigated in…
- Trial name
- ECHOMAX (NCT05351151)
- Testing
- bilateral ultra-sound guided maxillary and mandibular nerve blocks, Infiltration of Lidocaine 1%
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Toulouse
Pain, Postoperative
Comparison of Doses of Dexmedetomidine With Bupivacaine in Caudal Block for Duration of Analgesia in Paediatric Infraumblical Surgeries.
Various methods are used to control post-operative pain among children. Amongst these methods, caudal block is one of the most favoured, prominent and dependable methods for providing reliable analgesia in surgeries below…
- Trial name
- NCT04700228
- Testing
- Bupivacaine Hydrochloride, Dexmedetomidine
- Where
- Pakistan
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Dr. Ruth K.M. Pfau Civil Hospital, Karachi
Appendicitis
Transversus Abdominis Plane (TAP) Versus Local Anesthetic for Lap Appendectomies
This study is a prospective, double-blinded, randomized comparison of 2 patient cohorts. One group of patients will receive a transversus abdominis plane (TAP) block.
- Trial name
- NCT01575028
- Testing
- Ropivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Nationwide Children's Hospital
Fractures, Closed, Humeral Fractures
Regional Blocks for Lateral Condyle Fractures
The purpose of this study is to investigate the post-operative pain control in pediatric patients with closed lateral condyle fractures who undergo open reduction and percutaneous pinning.
- Conditions
- Fractures, Closed, Humeral Fractures, Pain
- Trial name
- NCT03796572
- Testing
- Ropivacaine, Puncture Wound and Dressing
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Pain, Postoperative
Bilateral Continuous Erector Spinae Blocks for Post-Sternotomy Pain Management: A Pilot Study
Overall Aim: To evaluate the feasibility and potential benefits of investigating bilateral continuous erector spinae blocks (BESB) for postoperative pain management in a small cohort of children undergoing surgical sternotomy…
- Trial name
- NCT03936387
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital