Clinical trials: Renal Dysfunction
Renal Insufficiency, Chronic
Montelukast for Treatment of Uremic Pruritus
In this study hemodialysis patients that underwent dialysis thrice weekly screen for uremic pruritus and 80 patients that at least have refractive pruritus that lead to sleep and daily activity disorders enroll in this study.
- Trial name
- NCT02559388
- Testing
- Montelukast
- Volunteers
- 73 people
- Sponsor
- Shiraz University of Medical Sciences
Pediatric End Stage Renal Disease, Hemodialysis
More Frequent In-Center Hemodialysis in Pediatric End Stage Renal Disease
A health kidney works 24 hours a day, 7 days a week to remove toxins and fluid from the body. Many children with permanent kidney failure undergo dialysis, a life saving procedure that takes the place of a kidney.
- Trial name
- NCT01352455
- Testing
- Hemodialysis
- Where
- 3 sites in United States, Canada
- Volunteers
- 7 people
- Sponsor
- Children's Hospital of Philadelphia
Kidney Failure
Application and Impact Assessment of Ultrasound Super-Resolution Blood Flow Imaging (URM) in Patients With Renal Failure
The aim of this study is to evaluate the utility of URM technology in imaging renal microcirculatory blood flow in patients with renal failure, and to investigate its clinical feasibility for assessing renal function, disease…
- Trial name
- URM (NCT07484308)
- Testing
- Ultrasound super-resolution blood flow imaging
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Ma Zhe
CKD (Chronic Kidney Disease) Stage 5D
Impact of CKD on Children and Their Families
Based on the available literatures, previous studies have investigated the impact of CKD and dialysis on patient's health among adult and elderly population.
- Trial name
- NCT04538443
- Testing
- functional capacity, muscle strength, Quality of life of children
- Volunteers
- 100 people
- Sponsor
- Cairo University
Acute Kidney Injury, Fluid Overload
Prospective, Multi-center, Single-arm, Observational Study. US FDA 522 Pediatric Post Market Surveillance Study.
The post market surveillance study will employ a prospective, multi-center, single-arm, observational design to capture data on children who undergo CRRT using the Carpediem™ system.
- Trial name
- NCT04608149
- Testing
- Carpediem System
- Where
- 6 sites in United States
- Volunteers
- 36 people
- Sponsor
- Mozarc Medical US LLC
Acute Kidney Injury, Chronic Kidney Diseases
Kidney Recovery After Acute Kidney Injury - Longitudinal Study
The endothelin (ET) system is an active target in human Acute Kidney Injury (AKI). Our primary hypothesis is that the circulating blood concentration of ET will be higher in patients with AKI than in matched controls.
- Trial name
- KRAKIL (NCT04551391)
- Testing
- Blood and urine sampling
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- NHS Lothian
Acute Kidney Injury
Preventing Acute Kidney Injury (AKI) in Pediatric Patients
The purpose of this study is to compare the effects of peri-operative administration of Aminophylline versus Saline placebo in the preservation of renal function and the attenuation of renal injury in pediatric patients…
- Trial name
- AKI (NCT03897335)
- Testing
- Aminophylline
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Le Bonheur Children's Hospital
Chronic Kidney Disease, Bacterial Infection
Study of the Pharmacokinetics of Daptomycin in Children With Renal Disease
The purpose of this study is to: 1. Study the pharmacokinetics and safety of daptomycin in children on hemodialysis (HD) and peritoneal dialysis (PD). 2. Determine urine, HD and PD clearance of daptomycin.
- Trial name
- NCT01012089
- Testing
- Daptomycin
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Oklahoma
Pure Red-cell Aplasia
A Study of Risk Factors for Anti-erythropoietin Antibody Positive Pure Red Cell Aplasia Among Patients With Chronic Kidney Disease Receiving Epoetin Alfa
The purpose of this study is to collect historical occurrences of risk factors that are potentially associated with the development of anti-erythropoietin (EPO) antibody positive pure red cell aplasia (PRCA) in participants with…
- Trial name
- NCT00211068
- Testing
- No intervention
- Where
- 22 sites in Brazil, France and 5 more
- Volunteers
- 124 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Pseudohypoaldosteronism
Phase II Study of the Pathophysiology and Treatment With Enalapril and Polystyrene Sulfonate for Pseudohypoaldosteronism, Type I
OBJECTIVES: I. Establish the sodium and potassium intake that will maintain a normovolemic state in a patient with pseudohypoaldosteronism. II.
- Trial name
- NCT00004328
- Testing
- enalapril, polystyrene sulfonate
- Volunteers
- 1 people
- Sponsor
- National Center for Research Resources (NCRR)
Acute Kidney Injury, Renal Replacement Therapy
FST Analysis Supporting Timely Therapy and Risk Assessment Via Clinical Decision Support for Kids
The goal of this study is to learn whether adding a clinical decision support tool to the electronic medical record helps clinicians use the furosemide stress test in critically ill children at high risk for severe acute kidney…
- Conditions
- Acute Kidney Injury, Renal Replacement Therapy, Pediatric Intensive Care Unit
- Trial name
- FAST TRACK (NCT07718464)
- Testing
- Furosemide Stress Test Clinical Decision Support Tool
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autosomal Dominant Polycystic Kidney Disease
A Study to Evaluate Homocysteine Metabolism and Endothelial Function in ADPKD
The purpose of this study is to assess homocysteine metabolism and systemic endothelial function at the early stages of the disease and determine the prognostic value of homocysteine, related metabolites, and markers of…
- Trial name
- HCY (NCT05193981)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Mayo Clinic
Ciliopathies, Nephronophthisis
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM)
The purpose of the C'IL-LICO RICM study is to develop innovative and transformative diagnostic and prognostic for patients suffering from ciliopathies leading to renal failure.
- Conditions
- Ciliopathies, Nephronophthisis, Senior-Loken Syndrome, Joubert Syndrome
- Trial name
- CILLICORIRCM (NCT04874909)
- Testing
- Blood sample, Urine sample
- Where
- France
- Volunteers
- 240 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Kidney Failure, AIDS-Associated Nephropathy
Prevalence of Proteinuria and Chronic Kidney Disease in Pediatric HIV-Infected Patients
Among adults with Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS), Chronic Kidney Disease (CKD) has previously been reported to occur in approximately 10% of children with HIV-infection.
- Conditions
- Chronic Kidney Failure, AIDS-Associated Nephropathy, HIV Infections
- Trial name
- NCT00153621
- Where
- United States
- Volunteers
- 320 people
- Sponsor
- Children's National Research Institute
Obesity, Type 2 Diabetes (T2D)
A Retrospective Real-World Cohort Study
The primary objectives are to determine the prevalence and overlap of major cardiometabolic diseases, identify multimorbidity clusters, and characterize demographic, clinical, laboratory, and treatment patterns across the cohort…
- Conditions
- Obesity, Type 2 Diabetes (T2D), Prediabetes, Cardiovascular Disease (CVD)
- Trial name
- SCALA-TK-CM (NCT07781371)
- Testing
- No treatment given
- Where
- Denmark
- Volunteers
- 100,000 people
- Sponsor
- Novo Nordisk A/S
Vesicoureteral Reflux, Renal Hypodysplasia, Nonsyndromic, 1
Antibiotic Prophylaxis and Renal Damage In Congenital Abnormalities of the Kidney and Urinary Tract
The exact role of urinary tract infection in the appearance of chronic kidney disease is unclear. Children with congenital malformations of kidney and urinary tract have the higher risk of impairment of renal function.
- Conditions
- Vesicoureteral Reflux, Renal Hypodysplasia, Nonsyndromic, 1, Chronic Kidney Disease
- Trial name
- PREDICT (NCT02021006)
- Testing
- nitrofurantoin, No prophylaxis, Amoxicillin-Potassium Clavulanate Combination
- Where
- Italy
- Volunteers
- 292 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Renal Failure Acute Chronic
Efficacy and Tolerability of the APD Treatment in PAED Patients
The Silencia PD (peritoneal dialysis) cycler offers a pediatric (PAED) mode with advanced features such as Time and Volume Optimization (TAVO), supporting precise and individualized treatment.
- Trial name
- SilenciaPAED (NCT07004907)
- Testing
- Treatment with the pedriatic mode of the APD cycler
- Volunteers
- 13 people
- Sponsor
- Fresenius Medical Care Deutschland GmbH
Chronic Renal Failure Patients With Hyperphosphataemia Receiving Hemodialysis
Post-marketing Surveillance of Kiklin Capsules in Hemodialysis Patients
The purpose of this survey is to evaluate the safety and efficacy of long-term use of Kiklin® Capsules in actual clinical settings.
- Trial name
- NCT01901107
- Testing
- Kiklin capsules
- Where
- 8 sites in Japan
- Volunteers
- 1,078 people
- Sponsor
- Astellas Pharma Inc
Chronic Kidney Disease Stage 1, Chronic Kidney Disease Stage 2
The Effect of Vitamin D3 Supplementation on Hepcidin and Ferritin Serum Levels in Children With Chronic Kidney Disease
The goal of this clinical trial is to analyze the effects of in vitamin D3 on serum hepcidin and ferritin levels among children with chronic kidney disease.
- Trial name
- NCT06706271
- Testing
- Vitamin D
- Where
- Indonesia
- Volunteers
- 43 people
- Sponsor
- Hasanuddin University
Chronic Kidney Disease
University of Michigan "Nephrology Research BioBank"
The purpose of the study is to create a Nephrology Tissue Biobank enabling the study of kidney disease from the perspectives of epidemiology, genetics and molecular biology.
- Trial name
- NCT00381121
- Where
- United States
- Volunteers
- 420 people
- Sponsor
- University of Michigan