Clinical trials: Renal Failure
Diabetic Nephropathies, Diabetes Mellitus, Type 2
Comparing The Effect Of Empagliflozin With Dapagliflozin In Reducing Proteinuria In Diabetic Patients With Chronic Kidney Disease With eGFR More Than 45ml/Min/1.73m²
This study was designed to compare empagliflozin and dapagliflozin in reducing protein leakage into the urine in adults with type 2 diabetes and chronic kidney disease.
- Conditions
- Diabetic Nephropathies, Diabetes Mellitus, Type 2, Renal Insufficiency, Chronic
- Trial name
- NCT07866235
- Testing
- Dapagliflozin, Empagliflozin (EMPA)
- Where
- Pakistan
- Volunteers
- 116 people
- Sponsor
- Lahore General Hospital
Chronic Kidney Diseases, Chronic Kidney Disease-Mineral and Bone Disorder
Chinese CKD-MBD Prevalence Survey (CRISS-MBD)
This is a multi-center cross sectional epidemiological study. The purpose of this study is to investigate the prevalence of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD) in Chinese population.
- Trial name
- NCT04714918
- Where
- 40 sites in China
- Volunteers
- 10,254 people
- Sponsor
- Limeng Chen
Kidney Transplantation, Acute Kidney Injury
Molecular Markers of Acute Kidney Injury in Elderly Deceased Donors
Scoring systems that combine donor clinical and morphological parameters to predict outcome of kidney transplantation lack enough specificity to be generally accepted.
- Trial name
- MoliDon (NCT06171438)
- Testing
- Urine Biomarkers, Gene expression profiling of donor kidneys by microarray, Gene expression profiling of recipient kidneys by microarray
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Endothelial Dysfunction, End-Stage Renal Disease
Ramipril vs. Amlodipine in Pediatric Hemodialysis Patients
The goal of this clinical trial is to learn if Ramipril works better than Amlodipine to reduce endothelial dysfunction in pediatric patients (aged 5-18 years) with end-stage kidney disease undergoing maintenance hemodialysis and…
- Conditions
- Endothelial Dysfunction, End-Stage Renal Disease, Pediatric Kidney Disease
- Trial name
- ADMA /PedsQL (NCT07879560)
- Testing
- Ramipril tablet, Amlodipine tablet
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Chronic Kidney Diseases
Clinical and Bioelectrical Impedance Profiles in Children With CKD
This cross-sectional study aims to assess body composition and hydration status using bioelectrical impedance analysis in children with chronic kidney disease.
- Trial name
- NCT07859371
- Volunteers
- 100 people
- Sponsor
- Assiut University
Diabetes, Renal Failure
MR-Evaluation of Renal Function-After-Pancreas-transplantation
The purpose of this study is to evaluate the beneficial effect of pancreas transplantation for long term kidney function in patients undergoing single-pancreas transplantation.
- Conditions
- Diabetes, Renal Failure, Pancreas Transplantation
- Trial name
- MERFAP (NCT01537445)
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Uppsala University
Acute Kidney Injury
Effect of Cumulative Chloride Dose on Development of Acute Kidney Injury in Critically Ill Children
The investigators would like to investigate the effect of chloride dosing on the development of acute kidney injury in critically ill patients.
- Trial name
- NCT02188602
- Where
- United States
- Sponsor
- Stanford University
Kidney Cancer, Renal Failure
Biomarkers in Blood and Tumor Tissue Samples From Patients With Wilms Tumor
RATIONALE: Studying samples of blood and tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT01314391
- Testing
- mutation analysis, polymerase chain reaction, laboratory biomarker analysis
- Volunteers
- 20 people
- Sponsor
- Children's Oncology Group
CKD
Washed Microbiota Transplantation (WMT) for Chronic Kidney Disease (CKD)
Wahsed microbiota transplantation (WMT) is a novel and promising therapeutic method for Chronic Kidney Disease (CKD). This clinical trail aims to evaluate the efficacy and safety of WMT in the treatment of CKD.
- Trial name
- NCT05838118
- Testing
- Fecal Microbiota Transplantation, Standard of Care for Chronic Kidney Disease
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Renal Transplantation, Chronic Renal Allograft Failure
Tacrolimus as Secondary Intervention vs. Continuation of Cyclosporine in Renal Transplant Patients With Chronic Renal Allograft Failure (CRAF)
The purpose of this study is to compare renal transplant recipients on cyclosporine maintenance therapy vs. those converted to tacrolimus-based immunosuppression with respect to renal outcomes.
- Trial name
- NCT00637143
- Testing
- Tacrolimus, Cyclosporine
- Where
- 13 sites in Canada
- Volunteers
- 107 people
- Sponsor
- Astellas Pharma Inc
Pediatric Patients Having Renal Failure and on Regular Hemodialysis
Effects of Curcumin on Inflammation and Oxidative Stress in Pediatric Patients on Regular Hemodialysis: A Randomized, Double-Blind, Placebo-Controlled Pilot Study
The study will be a randomised, double blinded, placebo controlled design. It will include 2 groups : trial group and placebo group Patients in both groups are children on regular hemodialysis The patients in the trial group will…
- Trial name
- NCT05627843
- Testing
- Curcumin capsules 1 gm
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Acute Kidney Injury
Preventing Acute Kidney Injury (AKI) in Pediatric Patients
The purpose of this study is to compare the effects of peri-operative administration of Aminophylline versus Saline placebo in the preservation of renal function and the attenuation of renal injury in pediatric patients…
- Trial name
- AKI (NCT03897335)
- Testing
- Aminophylline
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Le Bonheur Children's Hospital
End-Stage Renal Disease, Secondary Hyperparathyroidism
A Study to Evaluate the Safety of Paricalcitol Capsules in Pediatric Subjects Ages 10 to 16 With Stage 5 Chronic Kidney Disease Receiving Peritoneal Dialysis or Hemodialysis
The objective is to evaluate the safety of paricalcitol capsules in pediatric subjects, ages 10 to 16 years old, with Stage 5 chronic kidney disease (kidney failure) receiving peritoneal dialysis or hemodialysis and being treated…
- Trial name
- NCT01382212
- Testing
- paricalcitol
- Volunteers
- 13 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Acute Renal Failure, Critical Illness
Metabolic Aspects of Citrate Anticoagulation in Renal Replacement Therapy
Citrate anticoagulation is associated with metabolic side effects which are linked to a portion of citrate reaching systemic circulation.
- Trial name
- Citrate (NCT01361581)
- Where
- Czechia
- Volunteers
- 120 people
- Sponsor
- Charles University, Czech Republic
Children, Chronic Renal Failure
Effect of Strict Blood Pressure Control and ACE-Inhibition on Progression of Chronic Renal Failure in Pediatric Patients
In children with chronic kidney disease, progression to end-stage renal failure is associated with high patient morbidity and poor quality of life.
- Conditions
- Children, Chronic Renal Failure, Hypertension, Acquired Kidney Disease
- Trial name
- ESCAPE (NCT00221845)
- Testing
- ACE Inhibition, Intensified Blood Pressure Control, Add-on Angiotensin Receptor Blockade
- Where
- 33 sites in Czechia, France and 10 more
- Volunteers
- 400 people
- Sponsor
- Heidelberg University
Linperlisib, PRCA
Low-Dose Linperlisib Achieves Rapid Hematological Response in a Patient With Pure Red Cell Aplasia and Moderate-to-Severe Renal Insufficiency: A Case Report
This article reports a case of a 70-year-old male patient diagnosed with T-cell large granular lymphocytic leukemia (T-LGLL)-associated pure red cell aplasia (PRCA) complicated by moderate-to-severe renal insufficiency.
- Conditions
- Linperlisib, PRCA, Moderate-to-Severe Renal Insufficiency
- Trial name
- NCT07900282
- Testing
- linperlisib
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Peking Union Medical College Hospital
End Stage Renal Disease
Accelerated Mortality on Renal Replacement
The purpose of this study is to prospectively identify blood markers that identify chronic hemodialysis patients at risk for early (<90 days) and late (>= 1 year) mortality
- Trial name
- ArMORR (NCT00505180)
- Volunteers
- 10,018 people
- Sponsor
- Massachusetts General Hospital
Ureteral Obstruction, Neoplasms
Antibiotic Prophylaxis in Percutaneous Nephrostomy Placements and Replacements for Malignant Urinary Tract Obstruction
This study aims to find out whether taking antibiotics to prevent a urinary tract infection after a medical procedure called percutaneous nephrostomy (placement of a catheter directly into the kidney to keep it working after the…
- Conditions
- Ureteral Obstruction, Neoplasms, Acute Kidney Injury, Nephrostomy; Complications
- Trial name
- NCT06801405
- Testing
- antibiotic prophylaxis
- Where
- Brazil
- Volunteers
- 320 people
- Sponsor
- Barretos Cancer Hospital
Gout, Renal Insufficiency
Optimal Administration of Allopurinol in Dialysis Patients
Gout has a strong association with the metabolic syndrome, and it is often seen in patients with renal insufficiency. Allopurinol is a medication intended to lower uric acid and therefore prevents gout attacks.
- Trial name
- NCT02477488
- Testing
- Allopurinol
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Renal Insufficiency, Infection
Low-dose VS High-dose IV Cyclophosphamide for Proliferative LN in Children
Proliferative lupus nephritis (LN)is the predominant cause of morbidity and mortality in juvenile Systemic Lupus Erythematosus (SLE).
- Trial name
- Low/highIVCY (NCT01861561)
- Testing
- Low-dose intravenous cyclophosphamide, High-dose intravenous cyclophosphamide
- Where
- Thailand
- Volunteers
- 43 people
- Sponsor
- Mahidol University