Clinical trials: Respiratory Effort
Respiratory Distress Syndrome, Adult, Ventilator-Induced Lung Injury
Long Term Follow up of Children Enrolled in the REDvent Study
This is a prospective observational follow-up study of children enrolled in a single center randomized controlled trial (REDvent).
- Conditions
- Respiratory Distress Syndrome, Adult, Ventilator-Induced Lung Injury, Neurocognitive Dysfunction, Quality of Life
- Trial name
- NCT03709199
- Testing
- Ventilation Inhomogeneity, Diaphragm Ultrasound, Respiratory Inductance Plethysmography
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- Children's Hospital Los Angeles
Apnea, Respiration
Functional Bed Sheet Capturing Pressure Variation and Respiratory Effort Over Time
Apnea, a cessation in breathing is critical condition that affects the person regardless of age. In infants, an apneic state occurs when there is an absence of respirations for 20 seconds (Alvaro \& Rigatto, 2012).
- Trial name
- NCT03119103
- Testing
- Functional Bed Sheet
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Studio 1 Labs
Respiratory Insufficiency
Thoracoabdominal Asynchrony and Respiratory Distress
The investigators hypothesize that a simple 3-point tracking device that uses motion sensors attached to the abdomen and chest of a child will provide information regarding thoracoabdominal asynchrony (TAA), a major component of…
- Trial name
- NCT04626154
- Testing
- Objectively monitoring thoracoabdominal asynchrony
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Neonatal Respiratory Distress
DIaphragmatic Swing According to Cpap Flow Output in NEOnates (DISCONEO)
The hypothesis behind the study is that the performance of constant flow CPAP (Continuous Positive Airway Pressure) devices (CF-CPAP) is not inferior to that of variable flow CPAP devices (VF-CPAP) in terms of respiratory efforts…
- Trial name
- NCT07513051
- Testing
- CF-CPAP; CF-CPAP; VF-CPAP; VF-CPAP, VF-CPAP; VF-CPAP; CF-CPAP; CF-CPAP, CF-CPAP; VF-CPAP; VF-CPAP; CF-CPAP
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Speech Perception, Communication Barriers
The Effects of Operating Room COVID-19 Personal Protective Equipment on Speech Perception and Listening Effort
BACKGROUND: The aim of this study is to evaluate the effects of the combination surgical mask+N95 mask+face shield in operating room on speech perception and listening effort during the COVID-19 process.
- Conditions
- Speech Perception, Communication Barriers, Operating Rooms, Protective Devices
- Trial name
- NCT07505953
- Where
- Turkey (Türkiye)
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Deep Venous Thrombosis, Pulmonary Embolism
FUVID Study: Functional Characterization of Children With Chronic Venous Thromboembolic Disease
This is a multi-center prospective cohort study of patients with first-episode deep venous thrombosis and pulmonary embolism.
- Trial name
- NCT04583878
- Testing
- Blood draw (Visit 1), Blood draw (Visits 2 and 3)
- Where
- 14 sites in United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Paradoxical Vocal Fold Motion Disorder, Vocal Cord Dysfunction
Treatment of Paradoxical Vocal Fold Motion Disorder (PVFMD) With a Form of Respiratory Retraining Technique
Paradoxical Vocal Fold Motion Disorder (PVFMD), otherwise known as vocal cord dysfunction (VCD) is a laryngeal breathing disorder that has several potential causes. In some individuals, exertion is the predominant trigger.
- Trial name
- PVFMDRespRet (NCT02859974)
- Testing
- Respiratory retraining for PVFMD
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Influenza
Influenza Reminder Text-Messaging
Through a large, population-level quality improvement effort within the Children's Hospital of Philadelphia Care Network, we will evaluate text message reminders on flu vaccination rates for both patients with and without a…
- Trial name
- NCT06587984
- Testing
- Text message reminder
- Where
- United States
- Volunteers
- 228,361 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Respiratory Mechanics, Monitoring, Physiologic
Dynamic Non-invasive Monitoring of Inspiratory Effort
This prospective, observational cohort study aims to evaluate whether the dynamic monitoring of a patient's breathing effort can predict successful liberation from invasive mechanical ventilation.
- Conditions
- Respiratory Mechanics, Monitoring, Physiologic, Respiratory Insufficiency Requiring Mechanical Ventilation, Critical Illness
- Trial name
- NCT07839949
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Premature Birth
Changes in Respiratory Effort in Preterm Infants
Continuous Positive Airway Pressure (CPAP) is used to treat preterm infants with an immature respiratory center and having respiratory distress. CPAP requires intensive care monitoring and special qualified staff.
- Trial name
- NCT02014493
- Testing
- High Flow Nasal Cannulae (HFNC), Continuous Positive Airway Pressure (CPAP)
- Where
- Norway
- Volunteers
- 21 people
- Sponsor
- St. Olavs Hospital
Pediatric Acute Respiratory Distress Syndrome (PARDS)
Role of Dyspnea in the Progression of Pediatric Acute Respiratory Distress Syndrome
Pediatric acute respiratory distress syndrome (ARDS) is a life-threatening clinical syndrome, and dyspnea is its key symptom. Strenuous respiratory effort is a "second hit" for ARDS lungs, inducing changes in regional lung…
- Trial name
- NCT07750288
- Testing
- Noninvasive respiratory support, Transition from controlled to assisted mechanical ventilation, Weaning from mechanical ventilation
- Where
- Chile
- Volunteers
- 68 people
- Sponsor
- Universidad Nacional Andres Bello
Cystic Fibrosis
Exercise Training Study for Patients With Cystic Fibrosis
The aim of this study is to test the effect of a 6-month program of self-regulated, home-based exercise with telephone reinforcement on the cardiorespiratory fitness, pulmonary function and health-related quality of life of…
- Trial name
- NCT00609050
- Testing
- Self-Regulated Exercise with Telephone Reinforcement, Standard Treatment, Qualitative Approach
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Pittsburgh
Ventilation Therapy; Complications, Diaphragm Disease
Real-time Effort Driven VENTilator Management
This study is a Phase II controlled clinical trial that will obtain comprehensive, serial assessments of respiratory muscle strength and architecture to understand the evolution of ventilator-induced respiratory muscle weakness…
- Conditions
- Ventilation Therapy; Complications, Diaphragm Disease, Pediatric Respiratory Diseases
- Trial name
- REDvent (NCT03266016)
- Testing
- Computerized Ventilator Protocol, Esophageal Manometry, Respiratory Inductance Plethysmography (RIP)
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- Children's Hospital Los Angeles
Respiratory Muscles, Respiration, Artificial
Visualization of Inspiratory Effort and Respiratory Mechanics to Promote Lung- and Diaphragm Protective Ventilation
This is a multicentre prospective cohort trial in adult and pediatric ICU patients. The investigators will measure the effect of a patient's inspiratory effort during mechanical ventilation on the lungs and diaphragm.
- Conditions
- Respiratory Muscles, Respiration, Artificial, Respiratory Function Tests
- Trial name
- VIREM (NCT05459116)
- Testing
- Placement of nasogastric balloon
- Where
- 3 sites in Belgium, Canada
- Volunteers
- 150 people
- Sponsor
- University Hospital, Antwerp
Asthma in Children, Dyspnea; Asthmatic
Mechanisms for Dyspnea on Exertion in Children With Obesity and Asthma: Distinct Physiological Phenotypes
The overall objective of this study is to better understand the respiratory mechanisms provoking dyspnea on exertion in obese asthmatic children.
- Conditions
- Asthma in Children, Dyspnea; Asthmatic, Obesity, Childhood
- Trial name
- NCT04184609
- Testing
- Control, Albuterol
- Where
- United States
- Sponsor
- Ohio State University
High Flow Nasal Cannula
HFNC Flow Titration and Effort of Breathing in the PICU
High-flow nasal cannula (HFNC) is a method of non-invasive respiratory support used to decrease the effort of breathing (EOB) in patients with a wide variety of respiratory diseases in the pediatric intensive care unit.
- Trial name
- HFNCandEOB (NCT02793674)
- Testing
- Fisher & Paykel high flow nasal cannula, Vapotherm high flow nasal cannula
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Children's Hospital Los Angeles
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) (ICD-10 G93.3)
Munich ME/CFS Cohort Study
The Munich cohort study MUC-CFS aims at the characterization and long-term follow-up of myalgic encephalitis/chronic fatigue syndrome (ME/CFS) in young people aged up to 25 years, as well as at the identification of…
- Trial name
- MUC-CFS (NCT06005246)
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Technical University of Munich