Clinical trials: Respiratory Function
Laryngeal Mask Airway, Children
Risk Factors for Pediatric Difficult Supraglottic Airway Placement and Ventilation
This study is designed to observe the occurrence of failure or difficulty during placement of supraglottic airway devices (SGAs) and its associated risk factors in pediatric patients.
- Conditions
- Laryngeal Mask Airway, Children, Airway Management
- Trial name
- PEDSGAP (NCT06073977)
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 3,750 people
- Sponsor
- Alper Kilicaslan
Pulmonary Hypertension
Correlation of Right Atrial Strain With Pulmonary Hypertension, Right Ventricular Function And Outcome In Pediatric Patients
This observational study aims to assess correlation of right atrial strain measured by two-dimensional speckle tracking echocardiography with intraoperatively measured pulmonary artery pressures, other indices of right…
- Trial name
- NCT05699681
- Testing
- Transthoracic and transesophageal echocardiography
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Non-invasive Blood Pressure, Temperature
Evaluation Of The GE Monitor Product Line
This investigation is a multi-center study that will demonstrate that the GE Monitor meets equivalency and/or accuracy and/or performance criteria.
- Conditions
- Non-invasive Blood Pressure, Temperature, SpO2, Respiration
- Trial name
- NCT00730119
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- GE Healthcare
Down Syndrome
Evaluation of a Simplified Method for Diagnosis of Sleep Apnea in Children and Adults With Down Syndrome
People with Down syndrome are at increased risk of sleep apnea, not only from obstruction of the upper airway, but also of central origin.
- Trial name
- SAOS/T21 (NCT00951730)
- Testing
- Polysomnography
- Where
- 3 sites in France
- Volunteers
- 97 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Acute Brain Injuries, Consciousness Disorders
CONNECT-ME: Consciousness in Neurocritical Care Cohort Study Using fMRI and EEG
Detecting preserved consciousness in brain-injured patients by traditional clinical means requires presence of motor function. Otherwise, patients may be erroneously classified as being in a vegetative state.
- Trial name
- CONNECT-ME (NCT02644265)
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Tetraplegia, Spinal Cord Injury
Abdominal Functional Electrical Stimulation in Tetraplegia
People with high spinal lesions are at risk of respiratory complications because they have partial or complete paralysis of breathing muscles.
- Trial name
- NCT00202631
- Testing
- Surface Functional Electrical Stimulation
- Where
- United Kingdom
- Volunteers
- 4 people
- Sponsor
- South Glasgow University Hospitals NHS Trust
Nasal Injury
The Effect of Hydrocolloid Tape and Facial Massage in Premature Infants During Noninvasive Mechanical Ventilation
The aim of this study is to assess the effect of nasal injury prevention interventions (NIPI) (hydrocolloid tape and facial massage) on nasal septum injury, stress and comfort of premature neonates (28-35 weeks gestation)…
- Trial name
- NIPI (NCT05844345)
- Testing
- Hydrocolloid barrier group, Facial Massage group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ordu University
Preterm Birth
Repercussions of Respiratory Physiotherapy in Preterm Infants Under Mechanical Ventilation
Respiratory diseases are a major morbidity and mortality causes of neonatal requiring mechanical ventilation, especially in newborn preterm infants (PN), thus respiratory therapy becomes increasingly necessary in order to…
- Trial name
- preterm (NCT03159039)
- Testing
- Conventional Physiotherapy, Prolonged slow exhalation technique
- Volunteers
- 43 people
- Sponsor
- Universidade Cidade de Sao Paulo
Respiratory Tract Diseases, Influenza (Pandemic)
Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia
REMAP-CAP is a randomised, embedded, multifactorial, adaptive platform trial for community-acquired pneumonia. The purpose of this study is to evaluate the effect of a range of interventions to improve outcome of hospitalised…
- Conditions
- Respiratory Tract Diseases, Influenza (Pandemic), Influenza, Community Acquired Pneumonia
- Trial name
- REMAP-CAP (NCT02735707)
- Testing
- Ceftriaxone + Macrolide, Moxifloxacin or Levofloxacin, Piperacillin-tazobactam + Macrolide
- Where
- 408 sites in United States, Australia and 27 more
- Volunteers
- 20,000 people
- Sponsor
- UMC Utrecht
Respiratory Disease
A Study to Identify Errors in Inhaler Technique in Adults
This study will observe the inhaler technique of people using 13 different inhaler types; record any technique errors being made against checklists developed for each inhaler device based on their manufacturer's guidelines, and…
- Trial name
- SCORES (NCT04262271)
- Where
- United Kingdom
- Volunteers
- 734 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Nursing Students
The Effect of 4-7-8 Breathing Exercise Training on Sleep Quality
Research; it will be carried out Kilis 7 Aralik University Yusuf Serefoglu Health Sciences Faculty, Department of Nursing. The training will take approximately 20 minutes in an empty classroom and will be planned when the…
- Trial name
- NCT06103344
- Testing
- 4-7-8 Breathing Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Uğur Doğan
Spinal Hematoma, Spinal Abscess
RICALOR Italian Registry for Complications During Regional Anesthesia
Regional anesthesia is the cornerstone of modern postoperative analgesia, but concerns remain about possible adverse effects and complication.
- Conditions
- Spinal Hematoma, Spinal Abscess, Neurologic Manifestations, Cardiovascular Diseases
- Trial name
- RICALOR (NCT02038491)
- Testing
- regional anesthesia
- Where
- Italy
- Volunteers
- 63,692 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Paradoxical Vocal Fold Motion Disorder, Vocal Cord Dysfunction
Treatment of Paradoxical Vocal Fold Motion Disorder (PVFMD) With a Form of Respiratory Retraining Technique
Paradoxical Vocal Fold Motion Disorder (PVFMD), otherwise known as vocal cord dysfunction (VCD) is a laryngeal breathing disorder that has several potential causes. In some individuals, exertion is the predominant trigger.
- Trial name
- PVFMDRespRet (NCT02859974)
- Testing
- Respiratory retraining for PVFMD
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Out-of-hospital Setting, Dyspnea
Videoconferencing for the Management of Paediatric Dyspnoea in an Emergency Medical Call Centre
Dyspnoea is defined as the sensation of difficult or uncomfortable breathing experienced by a patient. It is a significant concern in emergency care, accounting for 8% of calls to the emergency medical call centre (EMCC) and 10%…
- Trial name
- VISIODYS-PED (NCT06847997)
- Testing
- Addition of telemedicine to standard medical dispatching process (Experimental Group)
- Where
- France
- Volunteers
- 339 people
- Sponsor
- Poitiers University Hospital
Gastric Perforation
High Altitude Area- A Risk Factor For Gastric Perforation?
This is an original case series on soldiers evacuated from HAA(High Altitude Area) over last one year(Sept 2017- Aug 2018) , of which 100% cases were found to have gastric antrum perforation.
- Trial name
- NCT03724513
- Where
- India
- Volunteers
- 5 people
- Sponsor
- ADITYA PAWAR
Congenital Central Hypoventilation Syndrome
International Congenital Central Hypoventilation Syndrome (CCHS) Registry and CCHS SHARE
The Center for Autonomic Medicine in Pediatrics (CAMP), in collaboration with leading CCHS clinicians, scientists, and patient advocacy groups around the world has built the first International CCHS (Congenital Central…
- Trial name
- NCT03088020
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Ilya Khaytin
to Test the Hypothesis That NHFOV is More Effective Than nCPAP in the Treatment of Respiratory Distress Syndrome (RDS) in Verypreterm Neonates
NHFOV as Primary Support in Very Preterm Infants With RDS
This will be a prospective, multi-center, two-arms,parallel, randomized, controlled trial with a superiority design,conducted in China.
- Trial name
- NCT05141435
- Testing
- infants receive primary non-invasive respiratory support by mean of nCPAP, infants receive primary non-invasive respiratory support by mean of NHFOV
- Where
- 3 sites in China
- Volunteers
- 360 people
- Sponsor
- Jiulongpo No.1 People's Hospital
Respiratory Distress Syndrome
Feasibility Study of Aerosolized Surfaxin in the Prevention of Respiratory Distress Syndrome (RDS) in Premature Infants
To evaluate the feasibility, safety and tolerability of aerosolized lucinactant delivered by nasal continuous positive airway pressure (nCPAP) for the prevention of respiratory distress syndrome (RDS) in premature infants.
- Trial name
- NCT00807235
- Testing
- Aerosolized lucinactant
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Windtree Therapeutics
Infant Respiratory Distress Syndrome, Ventilator Lung; Newborn
Closed-loop Automatic Oxygen Control (CLAC-4) in Preterm Infants
Two-center, randomised controlled, cross-over clinical trial in preterm infants born at gestational age below 34+1/7 weeks receiving supplemental oxygen and respiratory support (Continous positive airway pressure (CPAP) or…
- Trial name
- CLAC-4 (NCT03163108)
- Testing
- Closed-loop automatic oxygen control (CLAC) fast in addition to RMC, Closed-loop automatic oxygen control (CLAC) slow in addition to RMC
- Where
- 2 sites in Germany
- Volunteers
- 19 people
- Sponsor
- University Hospital Tuebingen
Minimal Invasive Surfactant Administration in Two Different Non-invasive Ventilation Modes to NRDS Infants
NIV-MISA-NRDS Trial: a Multicenter Study in China
BACKGROUND Non-invasive ventilation (NIV) treatment have been developed to minimize lung damage and to avoid invasive mechanical ventilation (IMV) in preterm infants, especially in those with gestational age less than 30 weeks.
- Trial name
- NCT05137340
- Testing
- Nasal continuous positive airway pressure, Non-invasive positive pressure ventilation
- Where
- China
- Volunteers
- 312 people
- Sponsor
- Peking University Third Hospital
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