Clinical trials: Respiratory Function
Healthy Lifestyle
Impact of Breathing Exercise Intervention on Breathing Sectors Engagement in Adolescent Runners During Load
Forty-six endurance runners, 23 males (age = 16.4±1.1) and 23 females (age=16.8±1.1) participated in our study. The contribution of abdominal, thoracic, and subclavian musculature to respiration and ventilation parameters during…
- Trial name
- breathing (NCT04950387)
- Testing
- Breathing exercises
- Where
- Czechia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of South Bohemia
Hepatopulmonary Syndrome
Supine Exercise in Hepatopulmonary Syndrome Patients With Orthodeoxia
Hepatopulmonary syndrome (HPS) is a rare condition that presents in about a quarter of patients with liver cirrhosis. In addition, a small subset of these HPS patients also have orthodeoxia, defined as a drop in oxygen levels…
- Trial name
- NCT04004104
- Testing
- Upright Exercise, Supine Exercise
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Unity Health Toronto
Duchene Muscular Dystrophy
Home-Based Tele-Rehabilitation for Respiratory Function in Children With Duchenne Muscular Dystrophy
This study evaluates the feasibility and preliminary clinical effects of a home-based tele-rehabilitation program aimed at improving respiratory function in children with Duchenne Muscular Dystrophy (DMD).
- Trial name
- NCT07629284
- Testing
- Home-Based Respiratory Telerehabilitation Program
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Samsung Medical Center
Pediatric Acute Respiratory Distress Syndrome
Pediatric Positive End Expiratory Pressure (PEEP) Titration Using Electrical Impedence Tomography (EIT)
The goal of this clinical trial is to perform a PEEP titration protocol and use EIT to identify the optimal PEEP at which lung overdistention and collapse are most effectively balanced.
- Trial name
- NCT06684119
- Testing
- Electrical Impedance Tomography positive end-expiratory pressure titration
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Hospital Los Angeles
Respiratory Distress Syndrome in Premature Infant, Surfactant Deficiency Syndrome Neonatal
Feasibility Study - Neofact
For therapy of respiratory distress syndrome (RDS) in premature babies, there are several established options. An important therapeutic aspect is the tracheal administration of exogenous surfactant into the child's lung.
- Trial name
- NCT04086095
- Testing
- Neofact application aid
- Where
- 2 sites in Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Tuebingen
Premature Birth, Fragility
Wireless MicroPremVitals Button Sensor in the NICU
A wireless and miniaturized vital sign (ECG, SpO2, Skin Temperature) sensor system, MicroPremVitals Button Sensors was developed by the Dr.
- Conditions
- Premature Birth, Fragility, Apnea of Prematurity, Bradycardia Neonatal
- Trial name
- NCT07732257
- Testing
- Wireless MicroPremVitals Button Sensor System
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Intensive Care, Neonatal, Neonatal Respiratory Distress Syndrome
Breastfeeding Infants Receiving Respiratory Support Trial
The purpose of this study is to assess whether two methods of breathing support in babies called 'Humidified High-Flow Nasal Cannula' oxygen (HHFNC) and 'nasal Continuous Positive Airways Pressure' (nCPAP) are compatible with…
- Conditions
- Intensive Care, Neonatal, Neonatal Respiratory Distress Syndrome, Continuous Positive Airway Pressure, Breast Feeding
- Trial name
- BIRRST (NCT02999165)
- Testing
- Breast feeding, Nasogastric feeding
- Where
- United Kingdom
- Volunteers
- 1 people
- Sponsor
- Imperial College Healthcare NHS Trust
Pneumonia
Effect of Neurophysiological Facilitation of Respiration on Blood Gases and Hospital Stay in Children With Pneumonia
The goal of this clinical trial is to investigate the effect of respiratory neurophysiological facilitation techniques on arterial blood gases, the severity of respiratory distress and duration of hospital stay in hospitalized…
- Trial name
- NCT07070271
- Testing
- Respiratory neurophysiological facilitation techniques, conventional chest physical therapy
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Asmaa Ahmed Abd El-samad
Acute Leukemia, Multiple Myeloma
INTEGRATIVE "MULTI-OMICS" AND FUNCTIONAL PLATFORM FOR THE COMPLETE DIAGNOSTIC CHARACTERIZATION OF TUMORS: THE ITALIAN TUMOR CHEMOGENOMIC PROFILER (IT-TCP)
This is a multicenter, experimental preclinical study conducted on primary samples from patients diagnosed with hematological or solid neoplasms defined as high risk.
- Conditions
- Acute Leukemia, Multiple Myeloma, Squamous Cell Carcinoma, Pleural Mesothelioma
- Trial name
- IT-TCP POS (NCT07403630)
- Testing
- Functional tests, Multi-omics analyses, Cytogenetics/ FISH
- Where
- 2 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Respiratory Disease
Does NIV-NAVA Improve Diaphragmatic Function in Preterm Infants
Non-Invasive Positive Pressure Ventilation (NIPPV) provides un-synchronized positive pressure and considered to be superior to nCPAP in preventing extubation failure.
- Trial name
- NCT05079412
- Testing
- Chest ultrasound
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Mount Sinai Hospital, Canada
Mouth Breathing Syndrome
Buteyko vs Diaphragmatic Breathing Technique Among the Adolescents
This study is about Mouth breathing adolescents. This study is a comparative study between buteyko and diaphragmatic breathing technique to check that which technique is more suitable for mouth breathing children.
- Trial name
- NCT07097467
- Testing
- Buteyko Breathing Technique
- Where
- India
- Volunteers
- 64 people
- Sponsor
- Dr. Kashish Sahota
Acute Viral Bronchiolitis
Prone Position in Acute Bronchiolitis
Acute viral bronchiolitis is the leading cause of community-acquired acute respiratory failure in developed countries (20 000 to 30 000 hospitalizations each year in France).
- Trial name
- PROPOSITIS (NCT03976895)
- Testing
- Supine position (SP), Prone position (PP)
- Where
- 16 sites in France
- Volunteers
- 452 people
- Sponsor
- Hospices Civils de Lyon
Respiratory Distress in Neonates, Mechanical Ventilation
Pressure Rise Time Modulation During Volume-Guaranteed Neonatal Ventilation
This study investigates the short-term physiological effects of pressure rise time modulation during volume-guaranteed ventilation in neonates.
- Trial name
- NCT07465237
- Testing
- Pressure Rise Time Adjustment
- Where
- Turkey (Türkiye)
- Volunteers
- 17 people
- Sponsor
- Hacettepe University
Sickle Cell Disease, Acute Chest Syndrome
Efficacy and Safety of Tocilizumab for Acute Chest Syndrome Treatment in Patients With Sickle Cell Disease
The purpose of this study is to determine whether a single infusion of tocilizumab is effective in reducing the time to successful weaning from both supplemental oxygen and any respiratory support, in pediatric and adult patients…
- Trial name
- TOCIACS (NCT06818266)
- Testing
- Tocilizumab (RoActemra®, 20 mg/mL).
- Where
- France
- Volunteers
- 130 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Respiratory Distress Syndrome
Extubation Readiness Study in Very Low Birthweight Infants
The objective of this study is to determine whether use of the spontaneous breathing trial allows for earlier successful extubation of very low birth weight (VLBW) infants who are intubated for >48 hours and have not yet been…
- Trial name
- NCT01471431
- Testing
- spontaneous breathing trial
- Where
- 2 sites in United States
- Volunteers
- 81 people
- Sponsor
- University of Pennsylvania
Infant, Premature, Diseases, Respiratory Tract Diseases
Effect of Volume Guarantee-High Frequency Oscillatory Ventilation on Cerebral Blood Flow in Neonates
A randomized controlled clinical trial evaluates cerebral blood flow changes associated with HFOV-VG in comparison to HFOV alone in preterm neonates with respiratory insufficiency during the period of invasive respiratory support
- Conditions
- Infant, Premature, Diseases, Respiratory Tract Diseases, Cerebral Blood Flow
- Trial name
- NCT05592431
- Testing
- High Frequency Oscillatory Ventilation with Volume Guarantee (SLE6000;SLE), High Frequency Oscillatory Ventilation (SLE6000;SLE)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Respiratory Insufficiency
Assessing Diaphragm Muscle Inactivity in Mechanically Ventilated ICU Patients
Background: Mechanical ventilation is a life saving intervention in patients with acute respiratory failure, for instance, due to infection or trauma.
- Trial name
- DIVIP (NCT02434016)
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- Unity Health Toronto
Obstructive Sleep Apnea
Knowledge, Attitude, and Practice of Pediatric Dentists Toward Obstructive Sleep Apnea Among Children
The main objective of this study is to assess the knowledge, attitude, and practice of Egyptian pediatric dentists toward obstructive sleep apnea among children.
- Trial name
- NCT06970873
- Testing
- Evaluation of Knowledge, Attitude, and Practice of Pediatric Dentists
- Volunteers
- 362 people
- Sponsor
- Cairo University
Thyroidectomy, Voice Alteration
Impact of Total Thyroidectomy on Voice and Swallowing
Purpose of this study is to evaluate the outcome of total thyroidectomy on vocal and swallowing function.
- Conditions
- Thyroidectomy, Voice Alteration, Swallowing Alteration
- Trial name
- NCT01607242
- Testing
- Endoscopy of larynx, Voice Handicap Index, Swallowing Assesment
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- University of Thessaly
Bradycardia, Hypoxemia
Nose-close and Abdomen-compression in Pediatric Flexible Bronchoscopy
The nasopharyngeal oxygen (NPO) with Nose-close (NC) and Abdomen-compression (AC) technique may use for support or rescue asphyxiated infants during Flexible bronchoscopy.
- Trial name
- NPO-NC-AC (NCT01629186)
- Testing
- NPO with Nose-close and Abdomen-compression
- Where
- Taiwan
- Volunteers
- 156 people
- Sponsor
- Cho-yu Chan, MD
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