Clinical trials: Respiratory Function
Apnea of Prematurity, Retinopathy of Prematurity
Use of Sucrose to Relieve Pain During Eye Exams in Infants
The purpose of this study is to see if an oral sucrose solution can comfort premature infants during their necessary eye exams. The investigators believe that the use of this solution prior to the eye exams will lead to a…
- Conditions
- Apnea of Prematurity, Retinopathy of Prematurity, Pain
- Trial name
- NCT00161694
- Testing
- sucrose solution
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Weill Medical College of Cornell University
Perennial Allergic Rhinitis
Efficacy Study for the Symptomatic Treatment of Perennial Allergic Rhinitis With a 1 Year Safety Extension
Double-blind phase: The objective of the study was to evaluate the efficacy and safety of Bilastine 20 mg, compared to Cetirizine and placebo for the treatment of perennial allergic rhinitis.
- Trial name
- NCT01127620
- Testing
- Bilastine, Cetirizine
- Volunteers
- 650 people
- Sponsor
- Faes Farma, S.A.
Bronchopulmonary Dysplasia
Trial of Late Surfactant for Prevention of Bronchopulmonary Dysplasia
The purpose of this study is to determine if late doses of Infasurf surfactant given when patients are receiving inhaled nitric oxide will interact to improve surfactant function and increase survival without BPD in treated…
- Trial name
- TOLSURF (NCT01022580)
- Testing
- Infasurf surfactant (ONY, Inc.)
- Where
- 21 sites in United States
- Volunteers
- 511 people
- Sponsor
- Roberta Ballard
Foreign Body Aspiration
Routine Chest X-ray Post Rigid Bronchoscopy for Foreign Body Extraction: is it Necessary?
Airway foreign body is one of the common emergencies. Its clinical presentation is variable, ranging from a clinically asymptomatic state to dire state of respiratory failure needing urgent attention and intervention.
- Trial name
- NCT06106503
- Testing
- chest x-ray, clinical examination
- Volunteers
- 100 people
- Sponsor
- Assiut University
Obstructive Sleep Apnea
Comparing Fitbit® Quality of Measured Sleep to Sleep Measured by Polysomnography in the Sleep Lab
This study is to evaluate a commercial tool on the market (Fitbit®) that also quantifies sleep. No one has studied how pediatric patients perform with it and how accurate it is in measuring their quality of sleep.
- Trial name
- NCT03066479
- Testing
- Fitbit, OSA questionnaire, Polysomnography
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Vidya Raman
Airway Control
Comparative Evaluation of Ambu AuraGain, LarySeal Pro and I-gel in Pediatric Airway Management for Day-Case Surgery Under Controlled Ventilation
This study aims to compare the Ambu AuraGain, LarySeal Pro LMA, and i-gel regarding their insertion characteristics, ventilation efficacy, risk of gastric insufflation, fiberoptic view quality, intraoperative and postoperative…
- Trial name
- NCT07274280
- Testing
- supraglottic airway device
- Where
- Egypt
- Volunteers
- 165 people
- Sponsor
- Kasr El Aini Hospital
Newborns
The Effect of Mother's Voice on the Levels of Pain and Comfort in Newborns
This study was conducted in a randomized controlled experimental type to determine the effect of maternal voice during care on pain and comfort level in term newborns receiving mechanical ventilation.
- Trial name
- Newborn (NCT06387888)
- Testing
- Listening to mother's voice
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Cystic Fibrosis
Combined Inspiratory Muscle and 'Whole Muscle' Training in Children With Cystic Fibrosis
To study the effects of an 8-week combined inspiratory muscle training and exercise (resistance+aerobic) program on of a lung volume, inspiratory muscle strength (maximal inspiratory pressure, PImax) and cardiorespiratory fitness…
- Trial name
- NCT01706445
- Testing
- Other
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidad Europea de Madrid
Pediatric Acute Respiratory Distress Syndrome
Pediatric Positive End Expiratory Pressure (PEEP) Titration Using Electrical Impedence Tomography (EIT)
The goal of this clinical trial is to perform a PEEP titration protocol and use EIT to identify the optimal PEEP at which lung overdistention and collapse are most effectively balanced.
- Trial name
- NCT06684119
- Testing
- Electrical Impedance Tomography positive end-expiratory pressure titration
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Hospital Los Angeles
Infant, Newborn, Diseases, Intubation Complication
Noninvasive Positive Pressure Ventilation During Neonatal Nasal Intubation
The goal of this study is to perform a quality control assessment of our local intubation protocol in any newborn infant requiring endotracheal intubation in the delivery room or neonatal intensive care unit at the Department of…
- Trial name
- IntubAID (NCT06139809)
- Testing
- Intubation
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Malignant Tumor of the Larynx
Stapler Versus Conventional Pharyngeal Repair After Total Larygectomy
This study was done to investigate the efficacy and safety of the linear stapler closure of the pharynx after total laryngectomy.
- Trial name
- NCT06256263
- Testing
- total laryngectomy
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Mansoura University
Apparent Life-Threatening Event in Infants Under One Year of Age
Apparent Life Threatening Events, Sudden Infant Death Syndrome and Muscarinic Receptors
Apparent Life-Threatening Events (ALTE) in infants often lead to severe neurological complications or to sudden death. In such situations, cardio-pediatricians and intensive care physicians have no specific diagnosis or…
- Trial name
- iALTE (NCT03278977)
- Testing
- Blood sample for specific analyzes
- Where
- 4 sites in France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Strasbourg, France
Congenital Heart Disease, Telerehabilitation
The Effect of Telerehabilitation Exercises in Children With Congenital Heart Disease
This study aims to investigate the effects of functional inspiratory muscle training on physical performance and quality of life in pediatric patients with congenital heart disease.
- Conditions
- Congenital Heart Disease, Telerehabilitation, Functional Inspiratory Muscle Training
- Trial name
- CHD (NCT07854171)
- Testing
- Inspiratory Muscle Training, Functional Inspiratory Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Izmir Democracy University
Asthma
Safety Study in Adolescent and Adult Patients With Asthma
E004-C2 is a continuation of E004-C for safety evaluations with additional 3 months to be able to assess the 6-month safety profile for E004 (epinephrine inhalation) versus placebo in a double-blinded manner.
- Trial name
- NCT01476904
- Testing
- Primatene Mist, Epinephrine inhalation
- Where
- 27 sites in United States
- Volunteers
- 208 people
- Sponsor
- Amphastar Pharmaceuticals, Inc.
Depression, Depressive Disorder
Mindful Breathing and tDCS for Depression
This study will investigate whether transcranial direct current stimulation (tDCS) targeting the dorsolateral prefrontal cortex (DLPFC) can enhance the therapeutic effect of mindful breathing training (MBT) for adolescent…
- Trial name
- NCT03897699
- Testing
- Transcranial Direct Current Stimulation, Mindful Breathing
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Minnesota
Altitude Hypoxia, Neonatal Encephalopathy
Neonatal Electrical Activity at Different Altitude Levels
In this study, the objective is to compare neonatal cerebral electrical activity within 3 days after birth across different altitude areas using amplitude-integrated electroencephalography (aEEG), and establish reference value…
- Trial name
- NCT05966714
- Testing
- aEEG
- Where
- 2 sites in China
- Volunteers
- 531 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Otitis Media With Effusion (OME), Otitis Media With Effusion in Children
Evaluation of Blowing Exercises Utilizing a Breathing Exercise Device in Otitis Media With Effusion
Otitis media with effusion (OME) is a common condition in which fluid collects behind the eardrum without signs of infection. It can cause hearing problems and discomfort.
- Conditions
- Otitis Media With Effusion (OME), Otitis Media With Effusion in Children, Breathing Exercise
- Trial name
- NCT06967506
- Testing
- Blowing exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Uşak University
Noninvasive Positive Pressure Ventilation, High Flow Nasal Cannula
A Multicentered Study on Efficiency of Noninvasive Ventilation Procedures
Noninvasive ventilation (NIV) is an alternative form of ventilatory support in critical care encompassing different modes of ventilation such as continuous positive airway pressure (CPAP), bilevel positive airway pressure (BiPAP)…
- Conditions
- Noninvasive Positive Pressure Ventilation, High Flow Nasal Cannula, Failure, Respiratory
- Trial name
- SAFE-NIV (NCT03066934)
- Testing
- noninvasive ventilation respiratory support
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 352 people
- Sponsor
- Akdeniz University
Cystic Fibrosis
Use of Capnography for the Follow-up of Cystic Fibrosis Children
The respiratory system involvement in cystic fibrosis(CF) influences the prognosis and course of disease. Respiratory assessment is based on spirometry, but its main parameter, the maximal expiratory volume in the first second…
- Trial name
- MUCOCAP (NCT04814797)
- Testing
- Capnography data included in Lung Clearance Index measurement
- Where
- 2 sites in France
- Volunteers
- 76 people
- Sponsor
- Central Hospital, Nancy, France
Premature Birth
Reliability Testing of Silverman-Andersen Retraction Score in Preterm Infants
Depending on their gestational age, preterm infants need several weeks with different types of breathing-support due to immature development of the lungs, respiratory muscles, chest-wall and respiratory center in the brain.
- Trial name
- NCT03199898
- Testing
- Silverman-Andersen Retraction Score
- Where
- 2 sites in Norway
- Volunteers
- 40 people
- Sponsor
- St. Olavs Hospital
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