Clinical trials: Resuscitations
Septic Shock, Severe Sepsis
Echocardiography in Septic Shock
BACKGROUND: Echocardiography can provide evaluation of right or left ventricular dysfunction and volume status during resuscitation of patients with sepsis and septic shock and guide intravenous vasopressor and fluid therapy.
- Trial name
- NCT02135796
- Testing
- Echocardiography
- Where
- United States
- Volunteers
- 700 people
- Sponsor
- Intermountain Health Care, Inc.
Prematurity, Oxidant Injury
Use of Blended Oxygen for Delivery Room Resuscitation of Very Low Birth Weight Infants
We propose a preliminary trial to evaluate the safety and efficacy of using more restricted oxygen during resuscitation for VLBW infants than is utilized currently in an effort to reduce the oxidant stress of such treatment, and…
- Trial name
- NCT00369720
- Testing
- Titration of oxygen in delivery room
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Neil Finer
Teamwork During Neonatal Resuscitation
Improving Teamwork for Neonatal Resuscitation
The Neonatal Resuscitation Program (NRP) is the curriculum used to teach providers how to care for newborns in the delivery room. Breakdowns in teamwork and communication contribute to NRP quality problems.
- Trial name
- NCT00651794
- Testing
- Teamwork training, Standard NRP curriculum, Skills practice with low-fidelity mannequin
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Hemorrhagic Shock, Pediatric Trauma
Effect of Resuscitation on Gastric Emptying Using POCUS in Pediatric Trauma Patients
Pediatric trauma often leads to hemorrhagic shock, which reduces blood flow to the digestive tract and delays gastric emptying. This delay can cause fluid and food to remain in the stomach, increasing the risk of pulmonary…
- Conditions
- Hemorrhagic Shock, Pediatric Trauma, Delayed Gastric Emptying, Gastric Dysmotility
- Trial name
- NCT07810907
- Volunteers
- 50 people
- Sponsor
- Assiut University
Hypothermia
Warming Mattress Versus Polyethylene Wrapping to Prevent Hypothermia in Preterm Newborns.
Mean axillary temperatures, taken during NICU resuscitation upon admission to the NICU, will not differ between VLBW babies who are occlusively wrapped and very low birth weight (VLBW) babies who are placed on thermal warming…
- Trial name
- NCT00603837
- Testing
- NeoWrap, InfaTherm
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Resuscitation
Co2 Monitoring at Preterm Delivery-Observational Study
CO2 data, serving as a proxy marker for tidal volume, might enable titration of tidal volume/pressure thereby providing optimal ventilation during neonatal resuscitation.
- Trial name
- COSTA (NCT04699708)
- Testing
- Carbon dioxide monitoring
- Where
- 2 sites in United Kingdom
- Volunteers
- 150 people
- Sponsor
- South Tees Hospitals NHS Foundation Trust
Respiratory Distress
Efficacy and Safety of Gastric Suctioning During Neonatal Resuscitation
The stomach of the newborn baby is often emptied soon after birth to prevent breathing problems (respiratory distress). Babies born with meconium-stained amniotic fluid and those with increased secretions associated with birth by…
- Trial name
- NCT00729989
- Testing
- Gastric suctioning
- Where
- United States
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Benjamin T. Stevens
Shortness of Breath, Chest Pain
Checklists Resuscitation Emergency Department
The study will systematically evaluate how an emergency manual-a collection of checklists and fact sheets-affects the performance of resuscitation teams during the management of priority one patients in an emergency department.
- Conditions
- Shortness of Breath, Chest Pain, Abdominal Pain, Altered Mental Status
- Trial name
- NCT05649891
- Testing
- Emergency Manual
- Volunteers
- 2,000 people
- Sponsor
- Region Skane
Cardiac Arrest
Comparison of Chest Compressions Performed With the Lower Limb and the Classical Method (Lower_limb_CPR).
Chest compressions, alongside early defibrillation, are the most important component of basic life support for adults. High-quality compressions give the patient a chance to survive cardiac arrest.
- Trial name
- Lower_limb_CPR (NCT07646496)
- Testing
- Instruction to perform chest compressions using the lower limb (foot)
- Where
- Poland
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Marcin Muża
Neonatal Resuscitation
Doppler Ultrasound Compared With Stethoscope to Assess Heart Rate (HR)
This is a prospective randomized controlled trial comparing heart rate measurement by Doppler ultrasound or auscultation with a stethoscope in newborn infants who require stabilization or resuscitation immediately after birth.
- Trial name
- NCT04242654
- Testing
- Handheld fetal doppler ultrasound
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Columbia University
Cardiac Arrest
Improving Cardiac Arrest Diagnostic Accuracy of Emergency Medical Dispatchers
The main goal of this project is to help 9-1-1 emergency medical dispatchers save the lives of more cardiac arrest victims. The investigators will develop teaching tools to help the dispatchers recognize abnormal breathing that…
- Trial name
- NCT01872325
- Testing
- Education
- Where
- Canada
- Volunteers
- 1,076 people
- Sponsor
- Ottawa Hospital Research Institute
Carrying Naloxone/Narcan on Their Person or in Their Vehicle, Being Trained to Respond to an Opioid Overdose
The Feasibility of Using the PulsePoint to Facilitate Overdose Education and Naloxone Distribution
This study is a feasibility trial to assess whether, in a random sample of 180 agencies where PulsePoint is already active, revised procedures (hereinafter PulsePoint-OD) to facilitate opioid overdose and naloxone distribution…
- Trial name
- PP-OD (NCT06523985)
- Testing
- Push messages (standard), Push messages (customized)
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Indiana University
Neonatal Resuscitation, Heart Rate Assessment
Impact of a Mobile Application for Heart Rate Assessment in Simulated Neonatal Resuscitation
NeoTapAdvancedSupport (NeoTapAS) is a free-of-charge mobile application that showed good accuracy in HR estimation. This study aims to evaluate the impact of NeoTapAS on timing of HR communication and of resuscitation…
- Trial name
- NCT03730025
- Testing
- Auscultation plus NeoTapAS, Auscultation without NeoTapAS
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital Padova
Dehydration
Hylenex-Assisted Resuscitation in Kenya (HARK) Trial for the Management of Dehydration
One of the leading health issues among patients, particularly children, presenting for care in low- and middle-income countries is dehydration.
- Trial name
- HARK (NCT02265575)
- Testing
- Hyaluronic Acid
- Where
- Kenya
- Volunteers
- 51 people
- Sponsor
- Massachusetts General Hospital
Cardiac Arrest
The Association Between Technical and Non-technical Skills in Real-life ALS Situations. Impact of Pit Crew Model on the Resuscitation Skills.
Cardiac arrest is handled by cardiopulmonary resuscitation which is a time critical emergency situation. The actions during resuscitation are lead by international guidelines.
- Trial name
- NCT03017144
- Testing
- Pit crew model education
- Volunteers
- 36 people
- Sponsor
- Turku University Hospital
Osbtetric Brachial Plexus Palsy
Kinematic Analysis of Latissimus Dorsi Transfer Results for Shoulder External Rotation Resuscitation
Neonatal brachial plexus palsy is a pathology that remains common and one of its sequelae is lack of external rotation of the shoulder.
- Trial name
- CinéLDSS (NCT06845228)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Intubation, Cardiopulmonary Resuscitation
Intubation During Resuscitation
The aim of the study was to compare time and success rates of four intubation devices ( in a cardiopulmonary scenario with uninterrupted chest compressions with a standardized manikin model.
- Trial name
- IDR (NCT02277951)
- Testing
- The Bonfils Intubation Fibrescope, The Video Rigid Flexing Laryngoscope, The C-MAC® S Video Laryngoscope
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- International Institute of Rescue Research and Education
Cardiopulmonary Arrest, Cardiac Arrest
Trial of Vasopressin and Epinephrine to Epinephrine Only for In-Hospital Pediatric Cardiopulmonary Resuscitation
Cardiac arrest has a very poor prognosis, especially with prolonged efforts at resuscitation, and unfortunately, survivors are often severely neurologically impaired.
- Trial name
- Vasopressin (NCT00628550)
- Testing
- Vasopressin, Epinephrine
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- University of Texas Southwestern Medical Center
Heart Arrest, Heart Arrest, Out-Of-Hospital
An Educational Program to Improve Cardiac Arrest Diagnostic Accuracy of Ambulance Telecommunicators
Cardiac arrest is the number one cause of death in Canada. It is often the first symptom of cardiac disease for the victims. Eighty-five percent of victims collapse in their own home.
- Conditions
- Heart Arrest, Heart Arrest, Out-Of-Hospital, Cardiac Arrest, Death, Sudden, Cardiac
- Trial name
- NCT03894059
- Testing
- Educational Intervention
- Where
- Canada
- Volunteers
- 12,224 people
- Sponsor
- Ottawa Hospital Research Institute
Vital Signs
The Effect of Postnatal Lying Position on Cerebral Oxygenation in Newborns
In the international delivery room guidelines, it is not specified which position is optimal for the baby stabilization. Here, the investigators want to evaluate the effects of the positions on postnatal adaptation and cerebral…
- Trial name
- NCT05868980
- Testing
- vital signs by postpartum position
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr. Behcet Uz Children's Hospital