Clinical trials: Rhizotomy
Spastic/Dystonic Quadriplegia, Cerebral Palsy (CP)
Outcomes of Neurosurgical Tone Management
Patients with spastic/dystonic quadriplegia (GMFCS IV/V) are often severely disabled by their tone, and require surgical tone management to improve quality of life, allow for better function, improve comfort, and range of motion.
- Trial name
- NCT07817745
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Boston Children's Hospital
Cerebral Palsy Spastic Diplegia, Gait, Spastic
The Effect of Selective Dorsal Rhizotomy Surgery on Walking in Children With Ambulatory Cerebral Palsy in Turkey
Cerebral Palsy (CP) is a motor disorder that develops during fetal brain development or due to non-progressive damage to the developing infant brain.
- Trial name
- NCT06617507
- Testing
- Group 1
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Acıbadem Atunizade Hospital
Spastic Cerebral Palsy, Walking, Difficulty
Predicting Postoperative Ambulation Following Selective Dorsal Rhizotomy Based on Preoperative Gross Motor Function Score
Cerebral Palsy (CP) is a neurodevelopmental disorder characterized by abnormalities in muscle tone, movement, and motor skills resulting from permanent, nonprogressive damage to the developing brain before, during, or after birth…
- Conditions
- Spastic Cerebral Palsy, Walking, Difficulty, Ambulation Difficulty
- Trial name
- NCT06610370
- Testing
- Group 1
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people
- Sponsor
- Acıbadem Atunizade Hospital
Post Traumatic Induced Spasticity
Selective Dorsal Rhizotomy as a Cost Effective and Safe Procedure as a Alternative to Intrathecal Baclofen Pump in Patients With Post Traumatic Spasticity
The investigators will investigate the selective dorsal rhizotomy in post traumatic brain and spinal cord injury induced spasticity to evaluate the efficacy of this procedure in reducing the tone of the spastic muscle groups.
- Trial name
- NCT07583277
- Testing
- Selective dorsal rhizotomy with neuromonitoring
- Volunteers
- 32 people
- Sponsor
- Assiut University
Cerebral Palsy
Medium to Long Term Outcomes of Selective Dorsal Rhizotomy
The main purpose of this study is to investigate the medium to long-term outcomes (3-10 years) after Selective Dorsal Rhizotomy (SDR) in ambulatory children and young people with cerebral palsy.
- Trial name
- MOSAiC (NCT06518889)
- Testing
- Selective Dorsal Rhizotomy
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Cerebral Palsy, Selective Dorsal Rhizotomy
Effect Of Closed Kinetic Chain On Hip Stability In Spastic Cerebral Palsy Post Selective Dorsal Rhizotomy
Purpose of the study: To evaluate the effect of closed kinetic chain on hip stability after selective dorsal rhizotomy on spastic cerebral palsy.
- Trial name
- NCT06646718
- Testing
- Close kinetic chain exercise group, Traditional physical therapy.
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Kafrelsheikh University
Diplegic Cerebral Palsy, Muscle Tone Abnormalities
Evaluation of Long-Term Effects of Selective Dorsal Rhizotomy Surgery on Function and Mobility in Children With Cerebral Palsy Using the International Classification of Functioning, Disability, and Health (ICF) Model
Cerebral Palsy (CP) is a neurodevelopmental disorder characterized by abnormalities in muscle tone, movement, and motor skills as a result of permanent, non-progressive damage to the developing brain before, during, or after…
- Trial name
- NCT06610357
- Testing
- Group 1
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Acıbadem Atunizade Hospital
Cerebral Palsy
Selective Dorsal Rhizotomy (SDR) Database
A national database is being set-up to collate clinical outcome information before and after children undergo Selective Dorsal Rhizotomy (SDR).
- Trial name
- SDR (NCT02904694)
- Volunteers
- 137 people
- Sponsor
- King's College London
Spastic Diplegia
Cortical Plasticity in Spastic Diplegia After Selective Dorsal Rhizotomy
The purpose of this study is to characterize the cortical connectivity changes in the brain of spastic diplegic children after Selective Dorsal Rhizotomy.
- Trial name
- NCT02535936
- Testing
- 3Tesla MRI with DTI-MRI and rsfcMRI under general anesthesia
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The University of Texas Health Science Center, Houston
Cerebral Palsy, Neurologic Disorder
Post-operative Lite Run Study
Lite Run is a new assistive device that may have FDA listing as a Class I device by mid 2017 based on clinical testing of adults, independent agency testing and in-house evaluations.
- Conditions
- Cerebral Palsy, Neurologic Disorder, Chromosome Abnormality, Spina Bifida
- Trial name
- NCT03135145
- Testing
- Lite Run Gait Trainer, Usual Treatments
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Gillette Children's Specialty Healthcare
Spastic Diplegia
Phase II Randomized Study of Selective Dorsal Rhizotomy and Physiotherapy Vs Physiotherapy Alone for Spastic Diplegia
OBJECTIVES: I. Assess the efficacy and safety of selective dorsal rhizotomy and physiotherapy compared with physiotherapy alone in improving gross motor function and reducing spasticity in children with spastic diplegia.
- Trial name
- NCT00004751
- Testing
- Surgery, Physical therapy
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Trigeminal Neuralgia
Comparative Study inTreatment of Trigeminal Neuralgia
This study aims to evaluate the results of percutaneous radiofrequency rhizotomy and the effectiveness of microvascular decompression for the treatment of trigeminal neuralgia and Comparing between them according the different…
- Trial name
- NCT04801407
- Testing
- percutaneous radiofrequency trigeminal rhizotomy, Microvascular decompression of the trigeminal nerve
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sohag University
Cerebral Palsy
The Effect of Selective Dorsal Rhizotomy on a Multidimensional Outcome Set in Children With Spastic Cerebral Palsy: a Retrospective Study
Cerebral palsy or CP is the single largest cause of childhood physical disability, with a prevalence of 2-3 per 1000 livebirths.
- Trial name
- NCT06340425
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Erector Spinae Plane Block, Opioid
Bilateral Erector Spinae Plane Block as an Opioid Sparing Technique for Selective Dorsal Rhizotomy in Pediatric Patients With Spastic Cerebral Palsy
This study aims to evaluate the efficacy of bilateral erector spinae plane block as an opioid-sparing technique for selective dorsal rhizotomy in pediatric patients with spastic cerebral palsy.
- Conditions
- Erector Spinae Plane Block, Opioid, Sparing, Selective Dorsal Rhizotomy
- Trial name
- NCT06600061
- Testing
- Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Spasticity as Sequela of Stroke, Spastic Cerebral Palsy
Radiosurgery Treatment for Spasticity Associated With Stroke, SCI & Cerebral Palsy
A scientific study is being done to test a special treatment for people who have spasticity or tight muscles. This treatment is called "stereotactic radiosurgery dorsal rhizotomy." It uses very accurate beams of radiation to…
- Conditions
- Spasticity as Sequela of Stroke, Spastic Cerebral Palsy, Spasticity, Muscle
- Trial name
- SPASM (NCT06070233)
- Testing
- stereotactic radiosurgery (SRS) dorsal root rhizotomy radiomodulation
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- Ohio State University
Cerebral Palsy
Effect of Designed Physical Training After Selective Dorsal Rhizotomy on Motor Function of Ambulant Children With Spastic Diplegia
The management of cerebral palsy is complex and requires a multidisciplinary approach. Selective dorsal rhizotomy is a neurosurgical technique that aims to reduce spasticity in the lower limbs and improve motor function.
- Trial name
- NCT04997044
- Testing
- Concomitant physical rehabilitation, Standard Orthotic Management, selective dorsal rhizotomy
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Cairo University
Bilateral Cerebral Palsy
Effects of Physical Training Following Selective Dorsal Rhizotomy on Non-ambulant Children With Bilateral Spastic Cerebral Palsy
Children with spastic bilateral cerebral palsy are late developers. delayed gross and fine motor development require early intervention to improve the child performance and avoid secondary impairments.
- Trial name
- NCT05006144
- Testing
- physical therapy excercises, Standard Orthotic Management, selective dorsal rhizotomy
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Spasticity
Optical Stimulation in Peripheral Nerves for Select Rhizotomy Procedures
The purpose of this study is to determine the safe and effective levels of optical stimulation in peripheral nerves of humans otherwise undergoing nerve lesioning in surgery.
- Trial name
- Rhizotomy (NCT00575536)
- Testing
- Rhizotomy for children with spasticity
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Vanderbilt University
Spastic Cerebral Palsy
Extended-release Epidural Morphine for Acute Post-operative Analgesia Following Selective Dorsal Rhizotomy in Children
The purpose of this proposal is to improve the investigators' current Selective Dorsal Rhizotomy (SDR) analgesia protocol by eliminating or minimizing the use of fentanyl in the post-operative period.
- Trial name
- NCT00955877
- Testing
- Extended-release Epidural morphine (EREM) 80, Extended-release Epidural Morphine (EREM) 120, Control: Saline
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Washington University School of Medicine