Clinical trials: Risk Behavior
Adolescents, Mood Disorders
Mobile-enhanced Group CBT for Adolescents at Risk Severe Mood Disorders
Although cognitive-behavioral therapy (CBT) has shown efficacy in reducing symptoms and rates of mood relapse in adolescents at high risk for severe mood disorders (SMD; i.e., bipolar I/II disorder and recurrent or unremitting…
- Trial name
- NCT04887155
- Testing
- Cognitive behavioral therapy (CBT)
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- University of California, Los Angeles
Sedentary Behavior, Physical Activity
MOVI-OLE! [Open Learning Environments]
This study will evaluate the effectiveness of MOVI-OLE! (Open Learning Environment), a school-based intervention designed to reduce sedentary time and enhance multiple aspects of child development, including cognitive function…
- Conditions
- Sedentary Behavior, Physical Activity, Cognitive Function, Mental Health
- Trial name
- MOVI-OLE! (NCT07103343)
- Testing
- MOVI-OLE intervention
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Depression, Substance-Related Disorders
Middle School to High School Transition Project: Depression and Substance Abuse Prevention
This study will implement a school-based program to prevent depression, academic failure, and substance use in at-risk adolescents transitioning from middle school to high school.
- Trial name
- CAST-T/HSTS (NCT00071513)
- Testing
- CAST-T/HSTS, Brief Intervention
- Where
- United States
- Volunteers
- 497 people, healthy volunteers welcome
- Sponsor
- University of Washington
Suicide, Alcohol Use Disorder
Qungasvik (Toolbox): Prevention of Alcohol/Suicide Risk in Alaska Native Youth
For the past 20+ years the investigators have focused on addressing two interrelated public health issues, alcohol use disorder (AUD) and suicide in Alaska.
- Trial name
- NCT05400135
- Testing
- Qungasvik (Tools for Life)
- Where
- United States
- Volunteers
- 542 people, healthy volunteers welcome
- Sponsor
- University of Alaska Fairbanks
Carbohydrate, Hypoxia
Isolated and Combined Effect of a Low Carbohydrate Diet and Exercise in Hypoxia in Patients With Type 2 Diabetes
The purpose of this study is to determine the effects of isolated chronic exercise in hypoxia and combined exercise in hypoxia with a low carbohydrate diet on hypoxia-induced transcription factor (HIF1-α); glycaemic control and…
- Conditions
- Carbohydrate, Hypoxia, Exercise, Diabetes Mellitus, Type 2
- Trial name
- NCT05094505
- Testing
- Exercise in normoxia, Control diet, Exercise in hypoxia
- Where
- 2 sites in Portugal
- Volunteers
- 42 people
- Sponsor
- Universidade do Porto
Child Rearing, Risk Reduction Behavior
Age 9 Follow-up of Preventive Intervention (Denver)
To examine the impact of prenatal and infancy home visiting by paraprofessionals and by nurses from child age 2 through 9.
- Conditions
- Child Rearing, Risk Reduction Behavior, Reproductive Behavior
- Trial name
- DenverY09 (NCT00438594)
- Testing
- home visitation
- Volunteers
- 584 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Adolescent Suicide, Suicidal Ideation
Shame-Focused Cognitive Behavioral Therapy For Reducing Suicide Risk In Adolescent Psychiatric Inpatients (SF-CBT)
This pilot randomized controlled trial (RCT) aims to evaluate the feasibility, acceptability, and preliminary efficacy of Shame-Focused Cognitive Behavioral Therapy (SF-CBT) among high-risk psychiatric inpatient adolescents.
- Conditions
- Adolescent Suicide, Suicidal Ideation, Suicidal Behavior, Shame
- Trial name
- SF-CBT (NCT07294001)
- Testing
- Supportive Therapy (ST)
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Peking University
Child Rearing, Adolescent Development
Follow-up of Families in Early Preventive Intervention
This project supports the post-third-grade assessment of 693 children and their families who were enrolled in a randomized trial of a program of prenatal and infancy home visitation by nurses that was epidemiologically and…
- Conditions
- Child Rearing, Adolescent Development, Reproductive Behavior, Risk Reduction Behavior
- Trial name
- MemphisYear9 (NCT00438516)
- Testing
- nurse home visitation
- Where
- United States
- Volunteers
- 627 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Overweight, Obese
Post-delivery Maternal-offspring Obesity and Metabolic Risk After a Prepregnancy Weight-loss Intervention
The goal of PrepareD is to examine whether the prepregnancy weight-loss intervention administered during the Prepare trial [NCT02346162] has an influence in the postnatal period.
- Conditions
- Overweight, Obese, Metabolic Disorders, Postpartum
- Trial name
- PrepareD (NCT06067126)
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Kaiser Permanente
Psychosocial Risk Factors
PSYCHosocial Risk Factors of AThletes, Evaluation of a Questionnaire Constructed by CHATGPT
The goal of this observational study was to assess themes generated by ChatGPT to help organize psychosocial risk factors in professional sport.
- Trial name
- PsyChAt (NCT07862855)
- Where
- France
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Overweight/Obesity, Puberty
Improving Health Among Disadvantaged Girls to Slow Pubertal Onset and Reduce Long-term Health Risks
This study is testing whether improving health in girls during the prepubertal period may slow the onset of puberty. This study will focus on prepubertal girls who have a high weight status (at or above the 85th percentile for…
- Conditions
- Overweight/Obesity, Puberty, Health Behavior, Cardiometabolic Health
- Trial name
- NCT07460544
- Testing
- Family-Based Treatment (FBT)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of Washington
Post Traumatic Stress Disorder, Depression
Randomized Control Trial on Trauma Focused CBT in Zambia
The purpose of this study is to study the effectiveness of Trauma Focused Cognitive Behavioral Therapy in subset of children who are affected by trauma with significant mental health symptomatology in order to 1) examine the…
- Conditions
- Post Traumatic Stress Disorder, Depression, Risk Behaviors
- Trial name
- NCT01624298
- Testing
- Trauma Focused Cognitive Behavioral Therapy
- Where
- Zambia
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Suicide Prevention
Feasibility Trial of a Single Session of Crisis Response Planning for Youth at High Risk for Suicide
The current study is a clinical trial, meaning a research study in which human subjects are prospectively assigned to one or more interventions to evaluate the effects of those interventions on health-related behavioral outcomes.
- Trial name
- NCT06164106
- Testing
- Virtual Crisis Response Planning, In-Person Crisis Response Planning, Crisis Risk Counseling
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Ohio State University
Suicide, Mental Health Issue
Proximal Risk for Suicide in Adolescents
The central hypothesis is that biometric data can continuously monitor and allow for early identification/intervention of escalating suicidal symptoms.
- Trial name
- NCT06400810
- Testing
- Analog Devices Inc.
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Oregon Health and Science University
Diarrhea, Malnutrition
Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development
Malnutrition is considered one of the most prevalent risk factors for morbidity and mortality in children under five. An estimated 20% of children in the developing world are malnourished [1] and poor nutrition is linked to more…
- Conditions
- Diarrhea, Malnutrition, Stunting, Wasting
- Trial name
- MAL-ED (NCT02441426)
- Where
- 8 sites in Bangladesh, Brazil and 6 more
- Volunteers
- 1,796 people, healthy volunteers welcome
- Sponsor
- Foundation for the National Institutes of Health
Breastfeeding, SUID
Social Media and Risk Reduction Teaching-Enhanced Reach
This study aims to improve adherence to American Academy of Pediatrics safe sleep (SS) recommendations and improve rates of initiation and duration of partial and exclusive breastfeeding (BF) through direct education of mothers…
- Conditions
- Breastfeeding, SUID, SIDS
- Trial name
- SMARTER (NCT04387552)
- Testing
- Prenatal Safe Sleep Mobile Health (mHealth) Messaging, Prenatal Breastfeeding Mobile Health (mHealth) Messaging, Postnatal Safe Sleep Mobile Health (mHealth) Messaging
- Where
- United States
- Volunteers
- 2,093 people
- Sponsor
- Boston University
Emotional Problem, Behavior Problem
Enhancement of Emotion Regulation Skills in Adolescents
For the current study, a prevention program is developed and applied to enhance the emotion regulation skills of adolescents. Before and after the application of the prevention program, all participants will be assessed for their…
- Trial name
- NCT04001140
- Testing
- Enhancement of emotion regulation skills
- Where
- Cyprus
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Cyprus
Cardiovascular Diseases, Coronary Disease
Hostility, Depression, Social Environment and CHD Risk
To examine the separate and interactive effects of hostility, depressive symptomatology and socioeconomic status (SES) in predicting coronary heart disease risk.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Depression
- Trial name
- NCT00005533
- Volunteers
- 592 people
- Sponsor
- Duke University
Condomless Sex, Human Immunodeficiency Virus (HIV)
Cape Town Young Women's Health CoOp
This two-arm cluster randomized trial tested a gender-focused comprehensive HIV testing and counselling (HTC) program, the Young Women's Health CoOp (YWHC) with a standard HTC program and targeted female adolescents (aged 16-19)…
- Conditions
- Condomless Sex, Human Immunodeficiency Virus (HIV), Sexually Transmitted Infections (STIs), Alcohol and Drug Use
- Trial name
- NCT02974998
- Testing
- Young Women's Health CoOp (YWHC), Standard HTC
- Where
- South Africa
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- RTI International
Exposure to Violent Event, Bullying
Electronic Pre-visit Questionnaire to Prompt Discussions of Youth Violence in Primary Care
Pediatricians are supposed to talk about youth violence at all heath supervision visits, however these types of conversations rarely occur. There have been no studies assessing tools to prompt these discussions.
- Trial name
- NCT02041182
- Testing
- Pre-Visit Questionnaire
- Where
- United States
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital