Clinical trials: Risk of Fracture
Osteoporotic Vertebral Compression Fractures
Impact of Diabetes on Patients With Osteoporotic Vertebral Compression Fractures After Vertebral Augmentation
Osteoporotic vertebral compression fractures are common and painful, especially in older adults. A minimally invasive surgery called vertebral augmentation is often used to relieve pain and stabilize the spine.
- Trial name
- NCT07884149
- Testing
- Percutaneous Vertebroplasty (PVP), Percutaneous Kyphoplasty (PKP)
- Where
- China
- Volunteers
- 360 people
- Sponsor
- The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine
Ankle Fracture
Brace Versus Casting in Pediatric Low Risk Ankle Fractures
Acute ankle fractures are common in children. Most of these are stable and have a low risk of problems in the future. Even though these fractures are benign, these injuries are often casted for a fixed time period, which is…
- Trial name
- NCT00132964
- Testing
- Below knee walking cast, Removable ankle brace
- Where
- Canada
- Volunteers
- 111 people
- Sponsor
- The Hospital for Sick Children
Fracture
Risk Taking and Fracture Study
Boys suffer a disproportionately large number of fractures compared to girls (55-60%). This study aims to determine why this is the case by identifying risk factors for wrist fractures.
- Trial name
- NCT01768598
- Testing
- Fracture - Boys, Fracture - Girls, Non Fracture - Boys
- Where
- 2 sites in Canada
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- Canadian Institutes of Health Research (CIHR)
Fracture, Fractures, Hip
The PREVENT Trial: a Pragmatic Cluster Randomized Controlled Trial of a Multifaceted Fracture Prevention Model for Long-term Care
Hip fractures occur nearly twice as often for older adults residing in long-term care as they do in older adults of a similar age still living in other settings.
- Conditions
- Fracture, Fractures, Hip, Osteoporosis
- Trial name
- PREVENT (NCT04947722)
- Testing
- PREVENT Program
- Where
- Canada
- Volunteers
- 3,060 people, healthy volunteers welcome
- Sponsor
- McMaster University
Cardiovascular Diseases, Fracture
Prevalence and Risk Factors for Common Diseases
By using national databases in Sweden the aim of the present project is to: 1. Investigate if the incidence of our most common diseases, such as fracture and cardiovascular disease, has changed from 1970-2017 2.
- Conditions
- Cardiovascular Diseases, Fracture, Cancer
- Trial name
- NCT04091035
- Testing
- To describe the incidence of disease and evaluate risk factors
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Anna Nordström
Fractures in Children, Apophysitis
Total Genotype Score, Growth, Maturation and Loading Exposure as Risk Factors for Injury in Elite Male Youth Football
A total genotype risk score was generated based on the findings of previous research for non-contact injury, non-contact muscle injury, tendon injury, ligament injury, fracture injury and apophysitis injury.
- Conditions
- Fractures in Children, Apophysitis, Muscle Strain, Ligament Injury
- Trial name
- NCT05220969
- Testing
- Total Genotype Risk Score
- Where
- 2 sites in United Kingdom
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- St Mary's University College
Open Fracture
Evaluation of STIMULAN Device and AI Model in Preventing Fracture Infections
This is a prospective, single-center, double-blind randomized clinical trial aimed at evaluating the efficacy and safety of the extended-release antibiotic device, STIMULAN, in preventing infections in patients with open…
- Trial name
- NCT06033534
- Testing
- STIMULAN
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Università Vita-Salute San Raffaele
Proximal Femoral Fracture
Proximal Femoral Fractures - Patient Population, Risk Factors, Surgical Performance and Outcome
Proximal femoral fractures are a typical pathology in elderly patients after a low-energy trauma. This study analyses preexisting risk factors for proximal femoral fractures as well as for failing to reach the previous functional…
- Trial name
- ProFi (NCT03768622)
- Testing
- surgery for pertrochanteric femoral fracture, surgery for femoral neck fracture
- Where
- Switzerland
- Volunteers
- 2,906 people
- Sponsor
- University Hospital, Basel, Switzerland
Osteoporosis, Fracture
Develop and Validate Ultrasonic Device for Osteoporotic Fracture Risk Assessment
Study to demonstrate that the Bone UltraSonic Scanner (BUSS) can aid in detection of osteoporosis and predict prevalent osteoporotic fractures.
- Conditions
- Osteoporosis, Fracture, Aging
- Trial name
- BUSS03 (NCT01123421)
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Artann Laboratories
Osteoporosis
Changes in Bone Mineral Density and Fracture Risk in Patients Receiving Androgen Deprivation Therapy for Prostate Cancer
The aim of this study is to determine the long term effects of two types of hormonal treatment for advanced prostate cancer (LHRH agonists and the antiandrogen bicalutamide)on the bone mineral density of patients.
- Trial name
- NCT00536653
- Testing
- Bicalutamide and Calcium/ Vitamin D supplementation, LHRH agonists (Goserelin acetate) and Calcium/ Vitamin D supplementation, LHRH agonists (Goserelin acetate)
- Where
- United Kingdom
- Volunteers
- 618 people
- Sponsor
- Wirral University Teaching Hospital NHS Trust
Hip Fracture
Nutritional Risk Factors for Hip Fracture: a Case Control Study
Low Body Mass Index (BMI) is a risk factor for hip fracture, but it is unknown if it is the low BMI per se that increases risk of hip fracture or if specific micro-nutrients contribute.
- Trial name
- NCT01738776
- Where
- Norway
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Sternum Wound Infection, Nonunion of Fracture of Sternum
Sternal Closure With STERNUMFIX in Patients With High Risk
The primary objective is to establish if the SternumFix System improves sternal closure. The study should test the hypothesis that in a high risk patient population with increased risk for the development of sternal wound…
- Trial name
- STEPHIX (NCT01408745)
- Testing
- Sternumfix, steel wire
- Where
- 4 sites in Germany, Switzerland
- Volunteers
- 166 people
- Sponsor
- Aesculap AG
Hip Fracture, Blood Loss
Can Thrombelastography Predict Blood Loss in Patients With Hip Fractures
Hip fractures are associated with a large hidden blood loss. That is, the total blood loss associated with hip fracture surgery is much greater than that observed intra operatively.
- Trial name
- NCT02297061
- Testing
- Thrombelastography analysis (TEG)
- Where
- Denmark
- Volunteers
- 180 people
- Sponsor
- Hvidovre University Hospital
Blood Transfusion, Hip Fracture Surgeries
Hip Fracture Surgery Timing and Blood Transfusion Risk in Patients on DOACs
This study looks at patients with hip fractures who are taking direct oral anticoagulants (DOACs), a type of blood thinner. In many hospitals, surgery for these patients is delayed because of concerns about bleeding, but waiting…
- Conditions
- Blood Transfusion, Hip Fracture Surgeries, Geriatric, Bleeding Complications
- Trial name
- OPTIMIZEDOAC (NCT07309848)
- Where
- 7 sites in Netherlands
- Volunteers
- 374 people
- Sponsor
- St. Antonius Hospital
Stress Fracture, Injury
Vitamin D Supplementation in the Armed Forces
The study will comprise of an original investigation that will take the form of a prospective intervention (two matched groups) study.
- Trial name
- D_SAF (NCT03963128)
- Testing
- Supplementation Vitamin D3
- Where
- United Kingdom
- Volunteers
- 4,450 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Femoral Neck Fracture, Osteoarthritis
Dual Mobility Cup in Total Hip Arthroplasty Preventing Dislocation in Patients at Risk
Retrospectively study reviewing 34 patients operated with dual mobility cups in total hip arthroplasty between January 2009 and June 2012 at Sundsvall Hospital.
- Trial name
- NCT01644227
- Where
- Sweden
- Volunteers
- 34 people
- Sponsor
- Sundsvall Hospital
Osteoporosis, Osteoporosis Risk
Risk of Osteoporotic Fracture in Home Care Patients in Turkey
This study will assess the incidence of osteoporosis and osteoporotic fracture risk of registered home health patients in the Anatolian side of Istanbul.
- Conditions
- Osteoporosis, Osteoporosis Risk, Osteoporotic Fractures
- Trial name
- NCT05738785
- Testing
- Document review and scanning
- Where
- Turkey (Türkiye)
- Volunteers
- 370 people
- Sponsor
- Uskudar State Hospital
Osteoporosis
Real-World Evidence of Adherence to Denosumab Therapy and Fracture Risk Associated With Drug Withdrawal: A Cross-sectional Study
In the light of current literature data, it is not recommended to discontinue Denosumab therapy without initiating another antiresorptive therapy.
- Trial name
- NCT06414616
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people
- Sponsor
- Trakya University
Nonunion of Fracture of Tibia (Diagnosis)
Risk Factors for Post-Operative Nonunion of Tibial Shaft Fractures Based on a Path Analysis Model
Tibial shaft fractures is common long tubular fracture that account for about 13.7% of all fractures. And the incidence of nonunion of tibial shaft fracture varied from 1% to 80%.
- Trial name
- NCT03928912
- Where
- China
- Volunteers
- 234 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Vitamin D Deficiency, Stress Fracture
Vitamin D3 Supplementation and Stress Fracture Occurrence in High-Risk Collegiate Athletes
The main objective of this study is to find a correlation between vitamin D deficiency and stress fracture occurrences in athletes who participate in high-risk activities.
- Conditions
- Vitamin D Deficiency, Stress Fracture, Athletic Injuries, Orthopedic Disorder
- Trial name
- NCT03395171
- Testing
- Cholecalciferol (Vitamin D3)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Prisma Health-Midlands