Clinical trials: Root Canal Treatment
Pulpitis - Irreversible
Full Pulpotomy Versus Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis
Background The European Society of Endodontology (ESE) and the American Association of Endodontists (AAE) position statements on the management of deep caries and exposed pulp recommended adoption and promotion of strategies…
- Trial name
- NCT06002698
- Testing
- Root canal treatment (Control), Full pulpotomy (Experimental)
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Apical Periodontitis
Clinical and Radiographic Success of Regeneration Using Injectable Platelet Rich Fibrin
Study aimed at assessing the clinical and radiographic success of pulp regeneration using injectable platelet-rich fibrin in mature permanent molars with apical periodontitis versus root canal treatment using Gutta Percha (GP)…
- Trial name
- NCT06086249
- Testing
- Regeneration using Injectable platelet-rich fibrin, Root canal treatment
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Lumbar Disc Herniation
Comparative Study Between UBE and PETD for the Treatment of Lumbar Spinal Canal Stenosis
OBJECTIVE Both unilateral biportal endoscopy technique(UBE) and percutaneous endoscopic transforaminal discectomy(PETD) are minimally invasive and effective surgical procedures for lumbar spinal stenosis.The object of this…
- Trial name
- NCT05033457
- Testing
- unilateral biportal endoscopy technique or percutaneous endoscopic transforaminal discectomy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shaanxi Provincial People's Hospital
Endodontic Disease, Root Canal Infection
Comparison of Antibacterial Efficacy of Three Final Irrigants
This study was conducted to determine the antibacterial affect of three different solutions used as final irrigant during endodontic therapy.
- Trial name
- NCT03853200
- Testing
- QMix Root Canal Irrigant, 17%EDTA+2%Chlorhexidine, EDTA
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Apical Extrusion During Root Canal Treatment
Measuring Apical Debris Extrusion With a Novel Laboratory Technique
Endodontic treatment occupies a critical role in dentistry, serving to prolong the longevity of teeth within the oral cavity and prevent early tooth loss.
- Trial name
- NCT07341451
- Testing
- ProTaper Gold Rotary File System, ProTaper Next Rotary File System
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Fatma Selenay Ucas Yildiz
Apical Periodontitis
Comparison of Healing of Apical Periodontitis in Periodontally Diseased and Healthy Patients.
Periodontal health may jeopardize the success of endodontic treatment.Intraorifice barrier apart from enhancing probability of success of endodontic treatment may also augment periodontal therapy as intra pulpal infection is…
- Trial name
- NCT03711942
- Testing
- Intra orifice barrier, Base, Control
- Volunteers
- 90 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Otomycosis
Comparative Efficacy of Topical Clotrimazole Versus 2% Salicylic Acid in Otomycosis
Otomycosis is a fungal infection of the outer ear canal that commonly causes itching, discomfort, discharge, and a feeling of blockage in the ear.
- Trial name
- NCT07535424
- Testing
- clotrimazole, 2% Salicylic Acid
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Mayo Hospital Lahore
Irreversible Pulpitis (toothache)
Garlic Oil As Root Filling Material in Primary Molars
The goal of this study is to test garlic oil mixed with zinc oxide as a potential root canal filling material of primary molars in children aged from four to eight years.
- Trial name
- NCT06755502
- Testing
- Garlic oil, Calcium Hydroxide, Iodoform, paste
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Root Canal Treatment in Children Primary Molars, Postoperative Pain
Efficiency of Sonic Activation During Root Canal Treatment of Primary Molars on Postoperative Pain and Facial Expressions
This study was conducted to evaluate the efficiency of sonic activation of 5%sodium hypochlorite during root canal treatment of primary molars on postoperative pain and facial expressions.
- Conditions
- Root Canal Treatment in Children Primary Molars, Postoperative Pain, Facial Expressions, Facial Emotions
- Trial name
- NCT07138937
- Testing
- Root canal treatment in primary molars with irreversible pulpitis, EDDY system for sonic activation of irrigation, side-vented needle
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Suez Canal University
Ultrasound Therapy; Complications
Ultrasound-Guided Versus Conventional Injection for Caudal Block
Caudal epidural block has been widely used, especially in pediatric surgery, to provide intraoperative and postoperative analgesia by affecting the region between T10 and S5 dermatomes in surgeries below the umbilical level.
- Trial name
- NCT03337191
- Testing
- Levobupivacaine, Morphine Sulfate, Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people
- Sponsor
- Ataturk University
Apexification, Root Canal Therapy
Antimicrobial Pastes and Clinical Cases of Apexogenesis
The aim of this study was to perform a clinical and microbiological evaluation of teeth with incomplete apexogenesis and traumatic necrosis that were treated with a revascularization technique, evaluating the microbial reduction…
- Conditions
- Apexification, Root Canal Therapy, Dental Trauma
- Trial name
- NCT03112291
- Testing
- Apexification
- Where
- Brazil
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Adriana Kelly de Sousa Santiago Barbosa
Pulp and Periapical Tissue Disease
Regenerative Endodontics for Non-vital Primary Molars
Non-vital primary molars will be treated with regenerative endodontic idea using different capping materials aiming to replace the necrotic pulp tissue with biological one and to provide perfect seal over the scaffold
- Trial name
- NCT05098483
- Testing
- Regeneration in primary molars by using MTA, Regeneration in primary molars by using biodentine, Conventional Root canal treatment in primary molars
- Where
- Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Root Canal Treatment
Retrospective Database Study: Influence of Post-endodontic Restoration Placement on Survival of Root Canal-treated Teeth
The aim of this study is to assess the influence (i.e. type and timing) of post-endodontic restorations on the survival of root canal-treated teeth and to determine the influence of patient-, tooth-, treatment-, and…
- Trial name
- NCT06441058
- Testing
- No patient treatment is associated with the study
- Where
- Germany
- Volunteers
- 541 people
- Sponsor
- University of Göttingen
Post Operative Pain
Postoperative Pain After the Use of Different Last Irrigation Method During Root Canal Treatment in Primary Teeth
This study was to evaluate and compare the postoperative pain levels after using EndoActivator and conventional endodontic syringe irrigation in root canal therapy of primary molars.
- Trial name
- NCT04197531
- Testing
- Irrigation Method
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Pulpitis - Irreversible
Pulpotomy vs Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis
high-quality evidence is needed to add to current knowledge and also assess the long-term outcomes for full/complete pulpotomy after carious pulpal exposure in patients with signs and symptoms indicative of irreversible pulpitis
- Trial name
- NCT05726357
- Testing
- vital pulp therapy
- Where
- Egypt
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Postoperative Complication, Root Canal Therapy
Comparison of Endodontic Flare up in Single Visit Root Canal Treatment Versus Multiple Visit Root Canal Treatment in Patients Visiting Scd, Swat.
This randomized controlled trial aims to compare the incidence of endodontic flare-ups in patients undergoing single-visit versus multiple-visit root canal treatment (RCT) at Saidu College of Dentistry, Swat.
- Conditions
- Postoperative Complication, Root Canal Therapy, Pulpitis - Irreversible
- Trial name
- NCT06972433
- Testing
- single visit root canal treatment, Multiple visit root canal treatment
- Volunteers
- 344 people
- Sponsor
- College of Physicians and Surgeons Pakistan
Periapical Diseases
Effect of Combined Root Canal Therapies in Mandibular Molars With Coexistent Mature and Immature Apices on the Healing Outcome
Recent advancements in dentistry are driven by the development of dental materials and therapies that support tissue regeneration, including the application of bioactive, biocompatible calcium silicate-based materials like…
- Trial name
- NCT07891611
- Testing
- Bioceramic apical plug, Regenerative endodontic procedure
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Al-Azhar University
Root Canal Obturation, Root Canal Filling
Outcome of SBO With Calcium Silicate Sealer vs WVC With Resin Based Sealer
A single blinded randomized controlled trial. 212 subjects (teeth), 106 in each of the 2 groups will be recruited from the patients referred to Kuwait Board of Endodontics for primary root canal treatment.
- Conditions
- Root Canal Obturation, Root Canal Filling, Sealer-based Obturation, Randomized Clinical Trial
- Trial name
- NCT04753138
- Testing
- TotalFill Bioceramic Sealer, AH+ Sealer
- Where
- Kuwait
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Kuwait Institute for Medical Specialization
Irreversible Pulpitis With Apical Periodontitis
PRP Regenerative Endodontics vs. Root Canal Treatment for Post-Op Pain and Healing in Mature Teeth
This randomized clinical trial aims to compare the effectiveness of regenerative endodontic treatment using platelet-rich plasma (PRP) with conventional root canal treatment (RCT) in mature single-rooted teeth diagnosed with…
- Trial name
- NCT07124962
- Testing
- Root Canal Therapy, Platelet-Rich Plasma (PRP) Revascularization
- Where
- Pakistan
- Volunteers
- 41 people
- Sponsor
- HITEC-Institute of Medical Sciences
Root Canal Infection, Pain, Postoperative
Effect of Cryotherapy and LLLT on Postoperative Pain After Root Canal Treatment
The aim of this study is to evaluate the effect of low-level laser therapy (LLLT) and intracanal cryotherapy applications on postoperative pain in endodontic interventions of primary molar teeth with apical periodontitis.
- Conditions
- Root Canal Infection, Pain, Postoperative, Cryotherapy Effect, Laser
- Trial name
- NCT05476445
- Testing
- Control, Laser, Cryotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ataturk University