Clinical trials: Root Canal Treatment
Postoperative Pain After Endodontic Treatment, Dental Anxiety
Effect of Intracanal Cryotherapy on Pain, Anxiety, and Salivary Irisin After Root Canal Treatment
Some people feel pain after a root canal treatment. This study will test whether intracanal cryotherapy, a final rinse of the tooth with cold sterile saline, can reduce this pain compared with a room-temperature rinse.
- Conditions
- Postoperative Pain After Endodontic Treatment, Dental Anxiety, Root Canal Treatment
- Trial name
- CRYO-IRIS (NCT07889050)
- Testing
- Intracanal Cryotherapy, Standard Room-Temperature Irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Tooth Discoloration Following Root Canal Treatment
TOOTH DİSCOLORATİON AFTER ROOT CANAL TREATMENT WİTH AH PLUS AND BİOROOT RCS
he purpose of this clinical study is to compare tooth color changes after root canal treatment using two different root canal sealers, AH Plus and BioRoot RCS, in upper front teeth.
- Trial name
- NCT07849296
- Testing
- AH Plus Root Canal Sealer, BioRoot RCS Root Canal Sealer
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Root Canal Treatment
Clinical Performance of AH Plus Jet® Root Canal Sealers in Single-cone Protocols
A prospective, parallel-group, randomised, post-market clinical follow-up investigation evaluating the performance and safety of the modified formula of the AH Plus Jet® Endodontic Sealer (also referred to as ES) and the…
- Trial name
- NCT07642284
- Testing
- AH Plus Jet® Endodontic Sealer, AH Plus Jet® Root Canal Sealing Material
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Dentsply Sirona Implants and Consumables
Tooth Discoloration Following Root Canal Treatment, Tooth Discoloration
Clinical Evaluation of Discoloration Induced by Root Canal Treatment in Vital and Devital Teeth
This prospective observational study aims to evaluate and compare tooth discoloration following root canal treatment in vital and devital teeth.
- Trial name
- NCT07781969
- Testing
- Root Canal Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Marmara University
To Evaluate the Effectiveness of Intra-canal Nano-ketrolac as a Medicament in Reducing Post-endodontic Pain in Patients Undergoing Root Canal Treatment
The Effect of Intra-Canal Ketorolac Application on Post-Endodontic Pain
After obtaining informed consent, the procedure begins with the administration of local anesthesia to ensure patient comfort. A standard approach involves using 2% lidocaine with 1:100,000 epinephrine, delivered either via…
- Trial name
- Post-Endodonti (NCT07064083)
- Testing
- intracanal nano-ketrolac, ketrolac gel
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Root Canal Treatment, Intra-operative Pain
This Clinical Trial Aims to Compare the Effectiveness of Two Intra-pulpal Cryotherapy Techniques-Endo-ice and Ice Sticks-in Decreasing Intra-operative Pain and Enhancing the Success of Local Anesthesia During Pulpectomy of Mandibular Molars With Symptomatic Irreversible Pulpitis.
The goal of this clinical trail is to compare the analgesic effect of endo-ice and ice-sticks in reducing intra-operative pain during pulpectomy in molars with Symptomatic Irreversible Pulpitis.
- Conditions
- Root Canal Treatment, Intra-operative Pain, Symptomatic Irreversible Pulpitis, Cryotherapy Effect
- Trial name
- NCT07264829
- Testing
- Endo-ice (Refrigerant Spray), Ice-sticks
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Dow University of Health Sciences
Root Canal Treatment, Postoperative Pain
Different Kinematics Within a Single-File System and Postoperative Pain
The goal of this clinical trial is to evaluating the influence of single file rotary system for root canal instrumentation using different kinematics on postoperative pain, the primary purpose: measuring post-operative pain by…
- Conditions
- Root Canal Treatment, Postoperative Pain, Apical Periodontitis
- Trial name
- NCT07699432
- Testing
- Twisted Adaptive motion (TFA), canal pro jeni, forward reciprocation
- Where
- Jordan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Root Canal Treatment, Obturation Quality
Diagnostic Accuracy of a Deep Learning Framework for Automated Evaluation of Root Canal Obturation Quality From Periapical Radiographs
This study aims to develop and evaluate an artificial intelligence (AI)-based system that can automatically assess the quality of root canal fillings using dental X-ray images.
- Trial name
- NCT07684482
- Testing
- Deep learning model
- Volunteers
- 490 people
- Sponsor
- Cairo University
Root Canal Treatment, Irreversible Acute Pulpitis
Postoperative Pain Following Root Canal Treatment With Bioceramic Sealers
To evaluate and compare postoperative pain and extrusion of sealers following root canal treatment using NeoSealer Flo and CeraSeal bioceramic sealers
- Trial name
- NCT07574801
- Testing
- root canal treatment
- Volunteers
- 30 people
- Sponsor
- Cairo University
Irreversible Pulpitis, Post-endodontic Pain
Comparative Evaluation of Diclofenac Sodium and Ibuprofen for Post-Endodontic Pain Management
This randomized controlled trial aims to compare the effectiveness of Diclofenac sodium and Ibuprofen in reducing pain after root canal treatment.
- Conditions
- Irreversible Pulpitis, Post-endodontic Pain, Root Canal Treatment
- Trial name
- DIPI-PEP (NCT07565012)
- Testing
- Ibuprofen, Diclofenac sodium
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Root Canal Treatment, Irrigation Activation
Treatment Outcome and Patient-reported Outcomes in Patient Undergoing Non-surgical Root Canal Treatment With Different Irrigation Protocols
This study aims to evaluate and compare the clinical and patient-reported outcomes of passive ultrasonic irrigation (PUI) and laser-activated irrigation (LAI) versus conventional syringe irrigation in adult patients undergoing…
- Conditions
- Root Canal Treatment, Irrigation Activation, Oral Health Quality of Life (OHQoL) Was Assessed, Post Operative Pain After Root Canal Therapy
- Trial name
- NCT07453134
- Testing
- root canal treatment and intracanal medicament
- Where
- Thailand
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Root Canal Treatment
Retrospective Database Study: Influence of Post-endodontic Restoration Placement on Survival of Root Canal-treated Teeth
The aim of this study is to assess the influence (i.e. type and timing) of post-endodontic restorations on the survival of root canal-treated teeth and to determine the influence of patient-, tooth-, treatment-, and…
- Trial name
- NCT06441058
- Testing
- No patient treatment is associated with the study
- Where
- Germany
- Volunteers
- 541 people
- Sponsor
- University of Göttingen
Apical Extrusion During Root Canal Treatment
Measuring Apical Debris Extrusion With a Novel Laboratory Technique
Endodontic treatment occupies a critical role in dentistry, serving to prolong the longevity of teeth within the oral cavity and prevent early tooth loss.
- Trial name
- NCT07341451
- Testing
- ProTaper Gold Rotary File System, ProTaper Next Rotary File System
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Fatma Selenay Ucas Yildiz
Symptomatic Irreversible Pulpitis, Postoperative Endodontic Pain Following Emergency Root Canal Treatment
Tobradex as Intracanal Medicament
The goal of this prospective clinical study was to evaluate and compare the short-term effects of two intracanal medicaments-calcium hydroxide and a tobramycin-dexamethasone combination (Tobradex)-on postoperative pain following…
- Trial name
- NCT07332936
- Testing
- Calcium Hydroxide (Ca(OH)2), Tobramycin + Dexamethasone
- Where
- Saudi Arabia
- Volunteers
- 43 people
- Sponsor
- Umm Al-Qura University
Root Canal Treatment
Post-Endodontic Pain According to Menstrual Cycle Phases
This study aimed to evaluate whether the phase of the menstrual cycle affects pain after root canal treatment. A total of 99 patients (72 females and 27 males) who needed root canal treatment in lower molar teeth were included.
- Trial name
- PEP-MC (NCT07291518)
- Testing
- root canal treathment
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Ahter Sanal Cikman
Root Canal Treatment, Irreversible Pulpitis With Apical Periodontitis
Effect of Probiotics, Double Antibiotic Paste, and Calcium Hydroxide on Postoperative Pain in Irreversible Pulpitis: A Randomized Trial
The goal of this clinical trial is to learn whether probiotics, double antibiotic paste (DAP), or calcium hydroxide paste help reduce postoperative pain after root canal treatment in adults with symptomatic irreversible pulpitis.
- Conditions
- Root Canal Treatment, Irreversible Pulpitis With Apical Periodontitis, Pulpitis - Irreversible, Post Operative Pain, Acute
- Trial name
- NCT07270159
- Testing
- Probiotic
- Where
- Pakistan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Root Canal Treatment
Comparison of AH Plus and WellRootST Root Canal Sealers in Terms of Postoperative Pain: One-Month Follow-up
The objective of this research was to identify which of the root canal sealers, AH Plus or WellRootST, yielded more effective outcomes regarding postoperative pain when applied to teeth diagnosed with apical periodontitis.
- Trial name
- NCT07246174
- Testing
- AH-Plus Epoxy Resin Sealer, bioceramic sealer
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medipol University
Irreversible Acute Pulpitis, Root Canal Treatment
Evaluation of the Effects of Different Irrigation Solutions and Activation Methods on Postoperative Pain and Quality of Life in Root Canal Treatment
Brief Summary: This prospective randomized controlled clinical trial aims to evaluate the effects of different irrigation solutions (NaOCl, HEDP) and activation methods (conventional syringe irrigation, EDDY, diode laser) on…
- Trial name
- NCT07241650
- Testing
- Irrigation with Sodium Hypochlorite and Conventional Syringe, Irrigation with Sodium Hypochlorite and EDDY, Procedure: Irrigation with Sodium Hypochlorite and Diode Laser
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara Yildirim Beyazıt University
Root Canal Treatment, Intracanal Medicament
The Success of Root Canal Treatments Performed Using Two Different Intracanal Medicaments
Previously untreated, asymptomatic, single-rooted maxillary anterior teeth with periapical lesions <5 mm, no fractures, resorption, calcification, or recent antibiotic use will performed two-visit root canal treatment.
- Conditions
- Root Canal Treatment, Intracanal Medicament, Post Operative Pain, Apical Periodontitis
- Trial name
- NCT07210177
- Testing
- Bio-C Temp Intracanal Medication, Metapaste Intracanal Medication
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ege University
Root Canal Treatment
Histological Evaluation in the Efficacy of GentleWave in Root Canal Pulp Tissue Debridement and Disinfection of Difficult to Reach Areas in Mandibular Human Molars II. An In-vivo Study.
The purpose of this study is to understand and learn better the efficacy of GentleWave and obtain histological evidence of the efficacy of this new technology done in-vivo
- Trial name
- NCT04105907
- Testing
- GentleWave
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The University of Texas Health Science Center, Houston