Clinical trials: Rupture
White Blood Cells
Study of the Cell Response in the Tear Film After Overnight Contact Lens Wear
The purpose of this study was to count and analyze the white blood cells in tear samples collected from study participants following sleep.
- Trial name
- CORNWALL (NCT01379768)
- Testing
- Lotrafilcon A contact lens, Lotrafilcon B contact lens, Clear Care Cleaning and Disinfection Solution
- Where
- Canada
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- CIBA VISION
Meniscus Tear
Motor and Sensory Deficits Following Partial Meniscectomy
To determine changes in thigh muscle function and knee pain after a partial meniscectomy surgery and to also determine the effects of applying electrical stimulation to the knee to determine if this improves thigh muscle function…
- Trial name
- NCT02100059
- Testing
- Transcutaneous Electrical Nerve Stimulation
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Creighton University
ACL Tear
Safe Return to Play After ACL Reconstruction
Recent studies report that as few as 44% of athletes undergoing ACL reconstruction were able to return to their prior level of competitive level of sports.
- Trial name
- NCT04827264
- Testing
- Safe Return to Play Following ACL Reconstruction Checklist
- Where
- United States
- Volunteers
- 222 people
- Sponsor
- Rothman Institute Orthopaedics
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Extended Post-Operative Oral Tranexamic Acid Dosing After ACL Reconstruction
The goal of this clinical trial is to learn whether taking oral tranexamic acid (TXA) for one week after anterior cruciate ligament (ACL) reconstruction improves recovery in adolescents and young adults aged 14 to 25 years.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Pain, Postoperative
- Trial name
- NCT07880743
- Testing
- Tranexamic Acid
- Where
- 6 sites in United States
- Volunteers
- 100 people
- Sponsor
- Dave Bernholt
ACL Tear
Augmentation of Anterior Cruciate Ligament Reconstruction Using Mesenchymal Stem Cells and Collagen Matrix Carrier
The goal of this observational study is to compare patient outcomes for reconstructive surgery of ACL tears. This study utilizes two randomized groups, one being the control group that receives standard ACL reconstructive…
- Trial name
- BioACL (NCT05582226)
- Testing
- ACL reconstruction, Mesenchymal stem cell implantation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Andrews Research & Education Foundation
Dry Eye
Effects of 3% Diquafosol on Tear Film and Vision-related Quality of Life in Orthokeratology Lens Related Dry Eye
Investigate the effect of 3% Diquafosol on tear film and vision-related quality of life in dry eye patients wearing orthokeratology lenses(OK lens), and to provide reference for clinical treatment.This prospective, open label…
- Trial name
- NCT06537349
- Testing
- 3% Diquafosol tetrasodium
- Volunteers
- 30 people
- Sponsor
- He Eye Hospital
Rotator Cuff Tears
A New Modified Suture Bridge Technique
We aimed to introduce a new modified suture bridge technique and report the clinical outcomes and radiological assessments of modified suture bridge technique for medium rotator cuff tears.
- Trial name
- NCT04825249
- Testing
- traditional suture bridge technique, modified suture bridge technique
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Postoperative Complications
Effect of Intravenous Nalbuphine on Emergence Agitation
Our primary objective of this study is to compare the effect of administration of single dose of intravenous nalbuphine given with induction of anesthesia with intravenous nalbuphine given at the end of surgery on the incidence…
- Trial name
- NCT03470077
- Testing
- IV nalbuphine 0.1 mg/kg with induction of anesthesia., IV nalbuphine 0.1 mg/kg at the end of surgery.
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Abdominal Pain, Ovarian Spillage
Single-port LC Might be Preferable for Managing Ovarian Dermoid Cyst.
Minimally invasive surgery has become the standard treatment for many gynecologic disease processes. In the last decade, numerous studies have demonstrated that laparoscopic approaches to various gynecologic oncology…
- Conditions
- Abdominal Pain, Ovarian Spillage, Endobag Rupture, Ovarian Reserve
- Trial name
- NCT02009228
- Testing
- Ovarian cystectomy
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Premature Rupture of Membranes
FOLCROM Trial: Foley Catheter in Rupture of Membranes
Multicenter randomized clinical trial comparing oxytocin versus oxytocin and foley catheter for induction in women who present with premature rupture of membranes who are not in labor.
- Trial name
- FOLCROM (NCT01973036)
- Testing
- Foley Catheter, Oxytocin
- Where
- 5 sites in United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Bruch Rupture, Choroidal Detachment
PASCAL: Safety and Complications, Experience After 1301 Consecutive Cases
To report the safety and incidence of adverse effects, during and after a successful photocoagulation for different pathologies using a Pattern Scan Laser (PASCAL) system and its modified settings
- Trial name
- NCT00803153
- Testing
- Panretinal Photocoagulation [Pattern Scan Laser (PASCAL) system]
- Where
- Mexico
- Sponsor
- Asociación para Evitar la Ceguera en México
Rotator Cuff Tear
Elevated Plasma Levels of TIMP-1 in Patients With Rotator Cuff Tear
The aim of the study was to investigate the levels of matrixmetalloproteinases and their inhibitors in blood samples from patients with rotator cuff tears and compare with blood samples from healthy matched controls.
- Trial name
- NCT01562145
- Testing
- Blood sampling
- Where
- Sweden
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
Chronic Hip Joint Pain, Prearthritic Hip Disease
Movement Pattern Training in People With Intra-articular, Prearthritic Hip Disorders
Intra-articular, prearthritic hip disorders (PAHD) result in substantial dysfunction in young adults and are proposed precursors to hip osteoarthritis (OA).
- Trial name
- NCT02913222
- Testing
- Rehabilitation
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- Washington University School of Medicine
Preterm Premature Rupture of Membranes
The Relation Between Serum Ascorbic Acid Concentration and Preterm Premature Rupture of Membranes
To study the association between maternal serum vitamin C concentration in women with preterm premature rupture of membranes (PPROM) and women without PPROM.
- Trial name
- NCT02635451
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Rotator Cuff Tear
A Long Term Follow-Up of Rotator Cuff Tear Patients Treated With Integrated Complementary and Alternative Medicine
This study is a prospective observational trial. Data of 4 hospitals will be used to find out the efficacy of conservative treatment in rotator cuff tear.
- Trial name
- NCT04566939
- Testing
- Herbal medicine, Chuna manual medicine, Pharmacopuncture
- Where
- South Korea
- Volunteers
- 168 people
- Sponsor
- Jaseng Medical Foundation
Chorioamnionitis, Chorioamnionitis Affecting Fetus or Newborn
Amniotic Fluid & the Preterm Gut
Background: Necrotizing enterocolitis (NEC) and sepsis in preterm infants have been linked to intestinal immaturity and preclinical gut microbiota alterations.
- Conditions
- Chorioamnionitis, Chorioamnionitis Affecting Fetus or Newborn, Necrotizing Enterocolitis of Newborn, Neonatal Sepsis, Early-Onset
- Trial name
- AMFIBIE (NCT07152106)
- Where
- 2 sites in Netherlands
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Maxima Medical Center
ACL - Anterior Cruciate Ligament Rupture
Soft-tissue Quadriceps Autograft ACL-reconstruction in the Skeletally-immature vs. Hamstrings
To date, the use of the quadriceps tendon as an autograft option in primary paediatric Anterior Cruciate Ligament (ACL) reconstruction has not been well studied.
- Trial name
- SQuASH (NCT03896464)
- Testing
- Soft tissue hamstring autograft, Quadriceps tendon autograft
- Where
- 6 sites in Canada, Japan
- Volunteers
- 352 people
- Sponsor
- McMaster University
Complete Tear, Knee, Anterior Cruciate Ligament, Rupture of Anterior Cruciate Ligament
Tibial Tunnel Placement for ACL Reconstruction
Although extensive research has been carried out on Anterior Cruciate Ligament (ACL) femoral tunnel placement, very little attention has been given to the tibial tunnel.
- Trial name
- NCT02374710
- Testing
- ACL Reconstruction: Anterior Tunnel, ACL Reconstruction: Posterior Tunnel
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Virginia
Rotator Cuff Tears
The Hug-up Test: A New, Sensitive Diagnostic Test for Supraspinatus Tears
We developed a new test, the "hug-up test," wherein elevation is resisted as the palm is held on the opposite shoulder with the elbow held in maximal anterior translation.
- Trial name
- NCT04954508
- Testing
- The hug-up test, EC test, FC test
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Rupture
Evaluation of Tibial and Femoral Tunnel Position After Arthroscopic Reconstruction of the Anterior Cruciate Ligament
The purpose of this study is to evaluate the accuracy of tunnel positions in anterior cruciate ligament reconstruction
- Trial name
- NCT01267435
- Testing
- Anterior cruciate ligament reconstruction
- Where
- Iran
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences