Clinical trials: Rupture
Anterior Cruciate Ligament Injuries, Quadriceps Muscle Atrophy
Vitamin D to Improve Quadricep Muscle Strength
Quadriceps muscle strength is one of the key determinants for patients to fulfill the Return-to-Play (RTP) criteria after an anterior cruciate ligament reconstruction (ACLR), in which the muscle size is directly linked to muscle…
- Conditions
- Anterior Cruciate Ligament Injuries, Quadriceps Muscle Atrophy, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- NCT05174611
- Testing
- Vitamin D3
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Rotator Cuff Tear Arthropathy, Spine Degeneration
Cutibacterium Acnes in Deep Tissues in Primary Spine and Shoulder Surgery
Obtain deep tissue samples from patients undergoing primary prosthetic surgery of the shoulder and patients undergoing primary instrumented surgery of the spine.
- Trial name
- NCT05355844
- Testing
- Benzoyl peroxide
- Volunteers
- 200 people
- Sponsor
- Hospital del Mar
Shoulder Pain, Rotator Cuff Injuries
Exercise Program in Patients With Shoulder Pain and Rotator Cuff Tear
Introduction: Atraumatic and degenerative rotator cuff tears are common in individuals over 55 years of age. This condition can have a high impact on social life and is associated with chronic pain, weakness and dysfunction of…
- Conditions
- Shoulder Pain, Rotator Cuff Injuries, Rehabilitation
- Trial name
- NCT03962231
- Testing
- Rotator Cuff Unloading Exercise Program, Rotator Cuff Loading Exercise Program
- Where
- Brazil
- Volunteers
- 78 people
- Sponsor
- Larissa Pechincha Ribeiro
Medial Collateral Ligament, Medial Mensical Tear
Knee Medial Collateral Ligament Recovery After Pie-Crusting Release Technique
Medial meniscus tears requiring surgical interventions are mostly being done by arthroscopic procedures. During the arthroscopy, accessing the medial joint space is challenging.
- Conditions
- Medial Collateral Ligament, Medial Mensical Tear, Shear Wave Elastography
- Trial name
- NCT06863077
- Testing
- MCL Pie-Crusting
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kastamonu University
Hip Injuries, Acetabular Labral Tear
A 12 Months Prospective Study Comparing Functional Outcome Scores in Hip Arthroscopic Labral Repair Versus Debridement
This study aims to address hip labral tears and compare arthroscopic labral repair versus debridement in non-athletic population aged 20 to 50 years old, including both sexes.
- Conditions
- Hip Injuries, Acetabular Labral Tear, Femoro Acetabular Impingement
- Trial name
- NCT06288867
- Testing
- Arthroscopic Labral Repair, Arthroscopic Labral Debridement
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Hamstring Injury, Muscle Rupture
Effect of NMES+ on Hamstring Lesion (3a/3b)
The goal of this clinical trial is to analyze the effect of the electrical stimulation superimposed onto movement in healthy semi-professional athletes who sustained a type 3a/3b hamstring strain injury.
- Conditions
- Hamstring Injury, Muscle Rupture, Hamstring Sprain
- Trial name
- NCT05786300
- Testing
- NMES+, Rehab
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Università degli studi di Roma Foro Italico
Dry Eye Syndrome, Ocular Surface Disease
Dry Eye Syndrome Description During Cataract Surgery, With Multimodal Analysis of the Ocular Surface
The main objective is to describe the characteristics of dry eye syndrome before and after surgery at one month of cataract surgery, using a multimodal analysis of the ocular surface.
- Trial name
- C-SS0 (NCT03923244)
- Testing
- OSDI survey
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Rotator Cuff Tears, Rotator Cuff Injuries
The Effect of Cross-Education on Shoulder Arthroscopy
The purpose of this study is to examine the effectiveness of a strength training protocol on the uninjured upper extremity either alone or with the addition of blood flow restriction (BFR) training on subjects who have undergone…
- Conditions
- Rotator Cuff Tears, Rotator Cuff Injuries, Rotator Cuff Repair
- Trial name
- NCT04470570
- Testing
- Cross-Education, Blood-Flow Restriction Training
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Cedars-Sinai Medical Center
Aneurysm Aortic, Aneurysm Aortic Root
Strength Tracking From Wall Tichness Over Aortic Biomechanics (STORM)
The aim of the study is to analyse the resected portion of aneurysmatic ascending aorta in order to assess its strength to rupture, standardise the various measurements performed within the lab and try to correlate these…
- Trial name
- STORM (NCT07453251)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS Policlinico S. Donato
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Exploring Prolonged AMR in ACL Reconstructed Patients
The goal of this observational study is to explore the significance of subject-reported outcomes and clinical parameters in relation to the occurence of prolonged presence of arthrogenic muscle responses (AMR) in anterior…
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, ACL
- Trial name
- NCT06430775
- Where
- Belgium
- Volunteers
- 190 people
- Sponsor
- University Ghent
Dry Eye Syndromes
Treatment of Dry Eye With Supplements
Dry eye syndrome (DES) is a highly prevalent ocular condition inducing an inflammatory response on the ocular surface. Common symptoms include ocular discomfort, visual impairment and instability of the tear film with potential…
- Trial name
- NCT01364311
- Testing
- Vitamac® Tag and Nacht capsules
- Where
- Austria
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Rotator Cuff Tears
Efficacy of Microfragmented Lipoaspirate Tissue in Arthroscopic Rotator Cuff Repair
Increasing the success rate of rotator cuff healing remains a tremendous challenge for orthopedic surgeons, which encourage the development of new biological therapies.
- Trial name
- NCT02783352
- Testing
- arthroscopic rotator cuff repair, autologous micro-fragmented adipose tissue
- Where
- 2 sites in Italy
- Volunteers
- 52 people
- Sponsor
- University of Milan
ACL - Anterior Cruciate Ligament Rupture
Intraoperative Analysis of Knee Kinematics During ACL Reconstruction - an Exploratory Study
Reconstruction of anterior cruciate ligament (ACL) is a common procedure in orthopaedic surgery, aimed at restoring stability to your knee.
- Trial name
- CINEGEN (NCT07655726)
- Testing
- Knee Cinematics
- Where
- France
- Volunteers
- 30 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Dry Eye Syndrome
Efficacy and Safety of the Ophthalmic Solution PRO-087 Versus Systane ® Ultra and Ultra Preservative Free (087LATAMFIV)
Efficacy and Safety of the Ophthalmic Solution PRO-087 versus Systane ® Ultra and Systane ® Ultra Preservative Free on the Tear Film Dysfunction Syndrome from Mild to Moderate Clinical trial To evaluate the effectiveness of…
- Trial name
- 087LATAMFIV (NCT03223909)
- Testing
- PRO-087, Systane Ultra, Systane Ultra Preservative Free
- Where
- Mexico
- Volunteers
- 326 people
- Sponsor
- Laboratorios Sophia S.A de C.V.
Dry Eye
Comparing Efficacy of Tea Tree Oil Versus Topical Azithromycin in Treating Dry Eye
This study aims to compare the effects of azithromycin and tea tree oil on the clinical outcomes and inflammatory profile of patients with MGD-associated DED.
- Trial name
- NCT06921525
- Testing
- Tea Tree Oil Topical Application Oil, Azithromycin Ophthalmic Solution
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ehab Mohamed Elsayed Mohamed Saad
Meniscus Tear, Retention; Meniscus
Circumferential Compression STITCH Repairs of Complex and Horizontal Cleavage Meniscal Tears
The purpose of this study is to understand the benefits and safety of the NOVOSTITCH PRO Meniscal Repair (NOVOSTITCH PRO) system. The meniscus is a tissue in the knee joint.
- Trial name
- NOVOSTITCH PRO (NCT04361487)
- Testing
- NOVOSTITCH™ PRO Meniscal Repair System
- Where
- 6 sites in United States
- Volunteers
- 33 people
- Sponsor
- Smith & Nephew, Inc.
Dry Eye Disease
Optical Coherence Tomography of Tear Film Dynamics In-Vivo
The purpose of this study is to evaluate a new instrument that takes digital images of tear film (a thin film that coats the eye that is made up of oil and water).
- Trial name
- NCT02554084
- Testing
- Optical Coherence Tomography
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Gene Abnormality, Meniscus Injury
Study on Susceptibility Genes of Anterior Cruciate Ligament, Patella Dislocation and Discoid Meniscus
Genomes of all sports medicine-related genes will be exome sequenced to find relevant gene mutations. To further study the molecular mechanisms and signaling pathways related to sports injury.
- Conditions
- Gene Abnormality, Meniscus Injury, Cruciate Ligament Rupture
- Trial name
- NCT04997538
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Tear
Bridge-Enhanced ACL Repair-Safety Study (BEAR Trial)
This study will assess the safety and early efficacy of a newly developed device, bridge-enhanced scaffold (MIACH™,) used to repair a torn anterior cruciate ligament (ACL.) Ten participants will undergo surgery with the new…
- Trial name
- BEAR (NCT02292004)
- Testing
- ACL Repair with MIACH Scaffold, Standard ACL Reconstruction
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Miach Orthopaedics
Rotator Cuff Tear, Postoperative Pain
Oral Ketorolac for Arthroscopic Rotator Cuff Repair
1. The investigators aim to examine the use of IV and oral ketorolac as an adjunctive agent to the standard of care pain protocol for postoperative pain control following arthroscopic rotator cuff repair. 2.
- Trial name
- NCT03967847
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University Hospitals Cleveland Medical Center
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