Clinical trials: Sacral Disorder
Enuresis, Nocturnal Enuresis
Transcutaneous Electric Nerve Stimulation (TENS) in Children With Enuresis
This is a randomized, double blind, placebo controlled study of the effect of Sacral Transcutaneous Electric Nerve Stimulation (TENS) in fifty-two children with monosymptomatic nocturnal enuresis (MNE).
- Conditions
- Enuresis, Nocturnal Enuresis, Urinary Incontinence
- Trial name
- NCT02600676
- Testing
- Transcutaneous Electric Nerve Stimulation (TENS) - active
- Where
- Denmark
- Volunteers
- 52 people
- Sponsor
- University of Aarhus
Pediatric ALL
Exploring the Minimum Effective Concentration and Volume of Ropivacaine for Sacral Plexus Anesthesia
The goal of this clinical trial is to explore the minimum effective concentration and volume of ropivacaine for sacral plexus anesthesia.
- Trial name
- NCT06711679
- Testing
- Low-dose ropivacaine, Medium-dose of ropivacaine, High-dose ropivacaine
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Yilin Zhao
Postoperative Pain, Analgesia
Comparison of Erector Spinae Plane Block and Penile Block in Hypospadias Surgery
In this study, we aimed to compare ultrasound-guided sacral erector spinae plane block and dorsal penile block on postoperative analgesic effect in hypospadias surgery.
- Trial name
- NCT04866368
- Testing
- The ultrasound-guided Sacral Erector spinae plane block, The dorsal penile block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kocaeli University
Fecal Incontinence, Childhood ALL
Management of FI After Surgery of ARM
The posterior sagittal approach to anorectal malformation (ARM) has radically changed the outcome of these patients, improving the preservation of anal sphincters, owing to their anatomical identification.
- Conditions
- Fecal Incontinence, Childhood ALL, Anorectal Malformations
- Trial name
- NCT05621629
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Gastrointestinal Motility Disorders in Children, Hirschsprung Disease
Improvement of Understanding of Pediatric Sacral Neuromodulation: Therapeutic Strategies and Outcome Variables
The goal of this study is to learn about the effects of sacral neuromodulation in pediatric patients with gastrointestinal motility disorders.
- Conditions
- Gastrointestinal Motility Disorders in Children, Hirschsprung Disease, Constipation - Functional
- Trial name
- SMART-GUT (NCT07519915)
- Testing
- SNM/MRI/EMG
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Friedrich-Alexander-Universität Erlangen-Nürnberg
Abdominal Injury, Pelvic Fracture
Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients
Unrecognized abdominal and pelvic injuries can result in catastrophic disability and death. Sporadic reports of "occult" injuries have generated concern, and physicians, fearing that they may miss such an injury, have adopted the…
- Conditions
- Abdominal Injury, Pelvic Fracture, Genital Hemorrhage, Lumbar Spine Injury
- Trial name
- NEXUS AP CT (NCT04937868)
- Testing
- There are no interventions associated with this study
- Where
- United States
- Volunteers
- 12,000 people
- Sponsor
- University of California, Los Angeles
Spinal Cord Stimulation, Deep Brain Stimulation
Implantable Systems Performance Registry
The Implantable Systems Performance Registry (ISPR) was developed to evaluate the long-term reliability and performance of market-released Medtronic Neuromodulation infusion and stimulation products.
- Conditions
- Spinal Cord Stimulation, Deep Brain Stimulation, Drug Infusion (Implantable Pumps), Sacral Neuromodulation
- Trial name
- ISPR (NCT00959296)
- Testing
- Various
- Where
- 50 sites in United States, Austria and 5 more
- Volunteers
- 10,981 people
- Sponsor
- MedtronicNeuro
Hypospadias, Caudal Block
Ultrasound Guided Sacral Erector Spinae Plane Block Versus Ultrasound Guided Caudal Block in Pediatric Undergoing Hypospadias Surgery
Randomized, parallel-group, assessor-blinded clinical trial at Tanta University Hospitals comparing ultrasound-guided sacral erector spinae plane block (sESPB) versus ultrasound-guided caudal epidural block for postoperative…
- Conditions
- Hypospadias, Caudal Block, Erector Spinae Plane Block, Pain, Postoperative
- Trial name
- NCT07099560
- Testing
- Ultrasound-guided sacral erector spinae plane block (sESPB), Ultrasound-guided caudal epidural block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Hypospadias, Postoperative Pain
Comparison of Sacral ESP Block and Caudal Block in Pediatric Hypospadias Surgery
Hypospadias surgery in pediatric patients requires effective postoperative analgesia to ensure patient comfort and reduce perioperative stress.
- Trial name
- NCT07619651
- Testing
- Sacral ESP Block, Caudal Epidural Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Hip Disease, Hip Dysplasia
PENG With LFCB vs. ESP Blocks for Pediatric Hip Surgery
This randomized controlled trial (RCT) compares the analgesic effectiveness of two regional anesthesia techniques-Pericapsular Nerve Group (PENG) block combined with Lateral Femoral Cutaneous Nerve Block (LFCB) versus Lumbar and…
- Conditions
- Hip Disease, Hip Dysplasia, Hip Arthropathy
- Trial name
- NCT07023094
- Testing
- Ropivacaine 0.2% for PENG Block, Ropivacaine 0.2% for LFCB, Ropivacaine 0.2% for L-ESPB
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Perinatal Solid Tumors of the Thoraco-abdomino-pelvic Region
Perinatal Thoraco-abdomino-pelvic Tumors Study
Congenital tumors are a rare diagnosis in the fetus and newborn. They differ from those of children and adults in terms of the nature, location and evolution of the tumor.
- Trial name
- CONTRAST (NCT06365268)
- Testing
- Collection of data from the patient's medical file
- Where
- 5 sites in France
- Volunteers
- 152 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Physical Activity
Daily Physical Activity in Myelomeningocele
Obesity is getting more common and challenging to treat in children and adolescents with myelomeningocele. Therefore, it is becoming more important to determine daily physical activity in these patients.
- Trial name
- NCT04186338
- Testing
- Omnidirectional accelerometer monitor (3x3 cm and 16 g, Actical®, Philips Respironics)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Marmara University
Spinal Cord Injuries
Development and Validation of a Bowel-routine-based Self Report Questionnaire for Sacral Sparing After Spinal Cord Injury
To develop a self-administered tool for assessment of sacral sparing after spinal cord injury (SCI) and to test its validity in individuals with SCI.
- Trial name
- NCT04951297
- Testing
- None, just observation
- Volunteers
- 102 people
- Sponsor
- Peking University Third Hospital
Overactive Bladder, Urinary Incontinence
Surface Nerve Stimulation Treatment for OAB in Children
The purpose of this study is to perform a randomized controlled investigation of the effect of surface nerve stimulation on functional daytime incontinence in children with OAB.
- Trial name
- NCT00282490
- Testing
- Nerve stimulator
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- University of Aarhus
Fecal Incontinence
Sacral Neuromodulation as Treatment for Fecal Incontinence
The objective of this study is to investigate if low level laser therapy will do more good than harm for patients with severe refractory fecal incontinence. It is a proof of concept study without a placebo arm.
- Trial name
- LLLT-FI (NCT03825575)
- Testing
- Low level laser therapy (LLLT)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- McMaster University
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Chronic Constipation With Overflow, Encopresis With Constipation and Overflow Incontinence
Sacral Neuromodulation in Children and Adolescents
The purpose of this study is to assess the efficacy of neuromodulation for treatment of chronic constipation and fecal incontinence in pediatric patients and to evaluate the differences between the invasive vs.
- Conditions
- Chronic Constipation With Overflow, Encopresis With Constipation and Overflow Incontinence, Hirschsprung's Disease, Anorectal Malformations
- Trial name
- NCT04713085
- Testing
- Invasive Sacral Neuromodulation, Non-invasive Sacral Neuromodulation
- Where
- Germany
- Volunteers
- 48 people
- Sponsor
- Friedrich-Alexander-Universität Erlangen-Nürnberg
Analgesia, Pain, Acute
Assessment of Efficacy of Sacral Erector Spinae Plane Block for Postoperative Analgesia in Pediatric Rectal Biopsies
The purpose of this study is to evaluate how sacral erector spinae block changed the postoperative analgesia requirements in pediatric patients undergoing rectal biopsies under general anesthesia.
- Trial name
- NCT06362811
- Testing
- Sacral Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Istanbul University
Urinary Incontinence, Spinal Cord Injury
Lumbar to Sacral Ventral Nerve Re-Routing
To assess the level of improvement in voiding function after lumbar to sacral ventral nerve re-routing procedure in Spinal Cord Injury and spina bifida patients
- Conditions
- Urinary Incontinence, Spinal Cord Injury, Spina Bifida
- Trial name
- NCT00378664
- Testing
- lumbar to sacral ventral nerve re-routing procedure
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Kenneth Peters, MD
Chronic Constipation With Overflow, Encopresis With Constipation and Overflow Incontinence
Non-invasive Sacral Nerve Stimulation in Children and Adolescents With Chronic Constipation
The purpose of this study is to assess the efficacy of additional neuromodulation for treatment of chronic constipation in pediatric patients
- Conditions
- Chronic Constipation With Overflow, Encopresis With Constipation and Overflow Incontinence, Hirschprung's Disease, Anorectal Malformations
- Trial name
- NCT04710433
- Testing
- Non-invasive Neuromodulation, Medical and Behavioral Therapy
- Where
- Germany
- Volunteers
- 59 people
- Sponsor
- Friedrich-Alexander-Universität Erlangen-Nürnberg